David Warner

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..This pilot project determined the feasibility and acceptability of the AAR strategy in anesthesiology practices...

..This qualitative, formative research identified themes to guide the development of a brief intervention used by the providers of surgical services to promote the use of telephone quitlines...

..This review will introduce basic concepts important to perioperative tobacco control and cover recent advances in the field...

..There are now proven methods to help them do so...

..In contrast, nicotine decreases SkBF responses to prolonged heating by activating noradrenergic nerves...

..Intervention opportunities are not exploited consistently in the surgical population; educational efforts directed at physicians in surgical specialties are indicated...

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..We conclude that an initial increase in cough is unlikely to occur among relatively healthy smokers who stop smoking and that changes in cough do not represent a barrier to maintaining abstinence for most smokers...

..This study tested the hypotheses that surgery increases the likelihood of smoking cessation and that cessation is more likely after major surgical procedures compared with outpatient surgery...

..It will also consider current evidence regarding how nicotine replacement therapy, a valuable adjunct to help patients maintain abstinence, may affect perioperative physiology...

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..The authors tested the hypothesis that abstinence from cigarette smoking contributes to psychological stress in the perioperative period...

..A basic understanding of the principles involved will help prevent the misuse of this important information...

..This study developed and tested a clinician-delivered intervention to facilitate quitline use by adult patients scheduled for elective surgery...

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..Although many factors determining survival may not be amenable to modification, the fact that arrests during nonregular working hours had worse outcomes may indicate that the availability of human resources influences survival...

..An intrinsic smooth muscle mechanism accounting for greater NO responsiveness in PASM vs. TSM is greater sGC activity...

..CONCLUSION: Pharmacological therapy for narcolepsy should be continued during the perioperative period. In addition, treated narcolepsy patients are at no increased risk for postoperative complications...

..The authors studied association between anesthetic exposure before age 4 yr and the development of reading, written language, and math learning disabilities (LD)...

..Thus, during muscarinic stimulation, stimulation of pGC relaxes ASM exclusively by decreasing [Ca(2+)](i), whereas stimulation of sGC decreases both [Ca(2+)](i) and Ca(2+) sensitivity...

..However, little is known about the practices, knowledge, and attitudes of Chinese anesthesiologists regarding perioperative tobacco interventions...

..On the basis of these data, a multicenter, double-blind, placebo-controlled, crossover, randomized trial was conducted to evaluate the effect of gabapentin on symptoms of chemotherapy-induced peripheral neuropathy (CIPN)...

..We tested the hypothesis that the use of subarachnoid block (SAB) for vaginal hysterectomy produces superior postoperative analgesia and improves functional status at 12 weeks postoperatively...

..We conclude that prolonged NO treatment induces decreased acute NO responsiveness in part by decreasing both sGC expression and sGC-specific activity...

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..To test the hypothesis that obesity is an independent risk factor for unplanned hospital admission or readmission among patients scheduled for ambulatory surgery in a tertiary medical center...

..To develop and validate time-efficient automated electronic search strategies for identifying preoperative risk factors for postoperative acute lung injury...

..This study found that pain severity was associated with greater depression but not smoking; however, smoking was associated with greater opioid use, independent of depression...

..These effects were more pronounced in cases where myofascial pain was not present...

..Secondary aims included determining the associations between smoking status, admission opioid use, and pain severity...

..min(-1).ng cGKI(-1), respectively). We conclude that prolonged NO treatment induces decreased acute NO responsiveness in PA in part by decreasing cGMP sensitivity. It does so by decreasing both cGKI expression and cGKI specific activity...

..Current smoking is associated with less favorable clinical presentations...

..The primary aim of this study was to determine the effects of smoking on treatment outcomes following multidisciplinary pain rehabilitation. A secondary aim was to assess the tobacco use characteristics of smokers with chronic pain...

..The primary aim of this study was to determine the influence of sex and the interactions between sex and smoking status on the immediate treatment outcomes of patients undergoing multidisciplinary pain treatment...

..Pancreatic cancer is an aggressive tumor associated with high mortality. Optimal pain control may improve quality of life (QOL) for these patients...

..However, there was no correlation between preoperative CO and nausea over the first 24 h. These preliminary data suggest that the effect of smoking in reduced PONV is not directly related to preoperative exhaled CO levels...

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..IMPLICATIONS: Morbid obesity significantly decreases respiratory system compliance and increases inspiratory resistance. Increased body weight, and not altered mechanics of breathing, was associated with worse PaO(2) during laparoscopy...

..A novel intrinsic smooth muscle mechanism accounting for greater NO responsiveness in PASM vs. TSM is thus greater cGMP responsiveness from increased cGKI-specific activity in PASM...

..2.25%, P = 0.006). No other differences between the groups were found. Although the study was retrospective and nonrandomized, the results suggest that the use of deep sedation for outpatient BMBA is as safe as using local anesthesia...

..Patients who received CPR in the cardiac catheterization lab have a remarkably frequent survival to hospital discharge rate. Long-term survival of these patients is only minimally reduced...

..The authors tested the hypothesis that the addition of intrathecal analgesia to general anesthesia would improve long-term functional status and decrease pain in patients undergoing radical retropubic prostatectomy...

..The goal of this project was to describe the frequency and natural history of perioperative changes in vision...

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..Based on experimental and clinical evidence, this study assessed the potential of intravenously administered lidocaine to reduce postoperative cognitive dysfunction after cardiac surgery using cardiopulmonary bypass...

..To determine 30-day mortality and predictors of mortality following perioperative pulmonary embolism (PE)...

..The period before surgery represents an opportunity for perioperative nurses, including certified registered nurse anesthetists (CRNAs), to address the tobacco use of their patients...

..Anesthesiologists can play a key role in helping their patients quit smoking. Effective tobacco control measures applied to surgical patients will not only improve immediate perioperative outcomes but also long-term health...

..The objective of this study was to determine the incidence and outcome of perioperative cardiac arrest (CA) in children younger than 18 yr undergoing anesthesia for noncardiac and cardiac procedures at a tertiary care center...

..However, no consensus has been reached regarding the best preoperative preparation regimen...

..Our results showed the effect to be short lived and associated with more frequent intraoperative use of vasopressors...

..This finding implies that this is not a mechanism by which hexanol interferes with receptor-G protein function...

..We investigated whether reversal of intraoperative atelectasis with the lung recruitment maneuver (RM) affects desflurane arterial concentrations during bariatric surgery...

..These differential effects also suggest a mode of anesthetic action that could be due to anesthetic-protein interactions and not simply anesthetic accumulation in the lipid membrane...

..The association between perinatal exposure to anesthetics during Cesarean delivery (CD) and development of learning disabilities (LD) was determined in a population-based birth cohort...

..This is consistent with recent clinical studies suggesting that IV lidocaine may cause airway narrowing in asthmatics. Practitioners should be aware of this potential complication...

..The aim of this study was to determine the association between smoking cessation and changes in pain symptoms by secondary analysis of a large longitudinal dataset of older adults...

..Hexanol may represent a useful experimental tool to study the effect of anesthetics on heterotrimeric G-protein function...

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..No differences in postoperative complications were found between groups. In conclusion, discontinuation of ACEI/ARA therapy at least 10 h before anesthesia was associated with a reduced risk of immediate postinduction hypotension...

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..We compare two periods, before formal introduction of ECMO in our institution (1993-1999, pre-ECMO era) and after ECMO became a formalized program (2000-2006, ECMO era)...

..Therefore, halothane should not affect the efficacy of beta2 agonists, as suggested by studies of in vivo animal models of asthma...

..Reversal of this cGMP-dependent process with DTT suggests that it occurs via mechanisms that are thiol redox sensitive...

..CONCLUSION: Prolonged air travel before major surgery significantly increases the risk of perioperative VTE. Such patients should receive more Intensive VTE prophylactic measures during the flight and throughout the perioperative period...

..These actions mimic those of volatile anesthetics on ASM, a circumstance suggesting that the primary alcohols may be useful tools for further exploring mechanisms of anesthetic effects on ASM...

..In these preparations, calcium levels can be controlled, and membrane receptor second messenger systems that alter calcium sensitivity are intact. ..

..This may cause increased VA/Q mismatch during anesthesia. We wish to test our hypothesis that injectable anesthetics may interfere less with hypocapnic bronchoconstriction than volatile anesthetics...

..Our overall goal is to develop effective tobacco use interventions for surgical patients; this project will be an important step in this process. ..