David Warner

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. pmc Survey of self-assessed preparedness for clinical practice in one Croatian medical school
    Katarina Bojanic
    Department of Obstetrics, Section of Neonatology, Merkur Clinical Hospital, Zagreb, Croatia
    BMC Res Notes 2:152. 2009
  2. doi request reprint Feasibility of tobacco interventions in anesthesiology practices: a pilot study
    David O Warner
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    Anesthesiology 110:1223-8. 2009
  3. doi request reprint Telephone quitlines to help surgical patients quit smoking patient and provider attitudes
    David O Warner
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Prev Med 35:S486-93. 2008
  4. ncbi request reprint Tobacco dependence in surgical patients
    David O Warner
    Department of Anesthesiology, Anesthesia Clinical Research Unit and Nicotine Dependence Center, Mayo Clinic, Rochester, Minnesota 55905, USA
    Curr Opin Anaesthesiol 20:279-83. 2007
  5. pmc Nicotine increases initial blood flow responses to local heating of human non-glabrous skin
    David O Warner
    Department of Anaesthesiology, Mayo Clinic College of Medicine, Rochester, MN, USA
    J Physiol 559:975-84. 2004
  6. ncbi request reprint Helping surgical patients quit smoking: why, when, and how
    David O Warner
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Anesth Analg 101:481-7, table of contents. 2005
  7. ncbi request reprint Anesthesiologists, general surgeons, and tobacco interventions in the perioperative period
    David O Warner
    Department of Anesthesiology, Mayo Clinic, 200 First St S W, Rochester, MN 55905, USA
    Anesth Analg 99:1766-73, table of contents. 2004
  8. ncbi request reprint Preoperative smoking cessation: the role of the primary care provider
    David O Warner
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 80:252-8. 2005
  9. ncbi request reprint Cough following initiation of smoking abstinence
    David O Warner
    Mayo Clinic, Rochester, MN 55905, USA
    Nicotine Tob Res 9:1207-12. 2007
  10. ncbi request reprint The effects of halothane pretreatment on manganese influx induced by muscarinic stimulation of airway smooth muscle
    D O Warner
    Department of Anesthesiology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Anesth Analg 84:1366-71. 1997

Research Grants

  1. ANANESTHESIA AND AIRWAYS
    David Warner; Fiscal Year: 2001
  2. ANANESTHESIA AND AIRWAYS
    David Warner; Fiscal Year: 2000
  3. ANANESTHESIA AND AIRWAYS
    David Warner; Fiscal Year: 1999
  4. ANESTHESIA AND AIRWAYS
    David Warner; Fiscal Year: 1993
  5. ANESTHESIA AND AIRWAYS
    David Warner; Fiscal Year: 1992
  6. ANESTHESIA AND AIRWAYS
    David Warner; Fiscal Year: 1991
  7. ANESTHESIA AND AIRWAYS
    David Warner; Fiscal Year: 1990
  8. Elective Surgery as a Teachable Moment for Smoking Cessation
    David Warner; Fiscal Year: 2007

Detail Information

Publications74

  1. pmc Survey of self-assessed preparedness for clinical practice in one Croatian medical school
    Katarina Bojanic
    Department of Obstetrics, Section of Neonatology, Merkur Clinical Hospital, Zagreb, Croatia
    BMC Res Notes 2:152. 2009
    ..The purpose of the survey was to identify self-perceived deficiencies in education and to establish a reference point for the later assessment of ongoing educational reform...
  2. doi request reprint Feasibility of tobacco interventions in anesthesiology practices: a pilot study
    David O Warner
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    Anesthesiology 110:1223-8. 2009
    ..This pilot project determined the feasibility and acceptability of the AAR strategy in anesthesiology practices...
  3. doi request reprint Telephone quitlines to help surgical patients quit smoking patient and provider attitudes
    David O Warner
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Prev Med 35:S486-93. 2008
    ..This qualitative, formative research identified themes to guide the development of a brief intervention used by the providers of surgical services to promote the use of telephone quitlines...
  4. ncbi request reprint Tobacco dependence in surgical patients
    David O Warner
    Department of Anesthesiology, Anesthesia Clinical Research Unit and Nicotine Dependence Center, Mayo Clinic, Rochester, Minnesota 55905, USA
    Curr Opin Anaesthesiol 20:279-83. 2007
    ..This review will introduce basic concepts important to perioperative tobacco control and cover recent advances in the field...
  5. pmc Nicotine increases initial blood flow responses to local heating of human non-glabrous skin
    David O Warner
    Department of Anaesthesiology, Mayo Clinic College of Medicine, Rochester, MN, USA
    J Physiol 559:975-84. 2004
    ..In contrast, nicotine decreases SkBF responses to prolonged heating by activating noradrenergic nerves...
  6. ncbi request reprint Helping surgical patients quit smoking: why, when, and how
    David O Warner
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Anesth Analg 101:481-7, table of contents. 2005
    ..Although specific strategies tailored for the surgical patient remain to be developed, there are steps that anesthesiologists can implement into their practices now that can help their patients quit smoking...
  7. ncbi request reprint Anesthesiologists, general surgeons, and tobacco interventions in the perioperative period
    David O Warner
    Department of Anesthesiology, Mayo Clinic, 200 First St S W, Rochester, MN 55905, USA
    Anesth Analg 99:1766-73, table of contents. 2004
    ..Intervention opportunities are not exploited consistently in the surgical population; educational efforts directed at physicians in surgical specialties are indicated...
  8. ncbi request reprint Preoperative smoking cessation: the role of the primary care provider
    David O Warner
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 80:252-8. 2005
    ....
  9. ncbi request reprint Cough following initiation of smoking abstinence
    David O Warner
    Mayo Clinic, Rochester, MN 55905, USA
    Nicotine Tob Res 9:1207-12. 2007
    ..We conclude that an initial increase in cough is unlikely to occur among relatively healthy smokers who stop smoking and that changes in cough do not represent a barrier to maintaining abstinence for most smokers...
  10. ncbi request reprint The effects of halothane pretreatment on manganese influx induced by muscarinic stimulation of airway smooth muscle
    D O Warner
    Department of Anesthesiology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Anesth Analg 84:1366-71. 1997
    ....
  11. doi request reprint Surgery as a teachable moment for smoking cessation
    Yu Shi
    Department of Anesthesiology and Nicotine Research Center, Mayo Clinic, Rochester, Minnesota 55905, USA
    Anesthesiology 112:102-7. 2010
    ..This study tested the hypotheses that surgery increases the likelihood of smoking cessation and that cessation is more likely after major surgical procedures compared with outpatient surgery...
  12. ncbi request reprint Effect of nicotine replacement therapy on stress and smoking behavior in surgical patients
    David O Warner
    Department of Anesthesiology, Anesthesia Clinical Research Unit, and Nicotine Dependence Center, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Anesthesiology 102:1138-46. 2005
    ....
  13. ncbi request reprint Smoking behavior and perceived stress in cigarette smokers undergoing elective surgery
    David O Warner
    Department of Anesthesiology, the Anesthesia Clinical Research Unit, and the Nicotine Research Center, Mayo Clinic, Rochester, Minnesota, USA
    Anesthesiology 100:1125-37. 2004
    ..The authors tested the hypothesis that abstinence from cigarette smoking contributes to psychological stress in the perioperative period...
  14. ncbi request reprint Airway obstruction and perioperative complications in smokers undergoing abdominal surgery
    D O Warner
    Department of Anesthesiology, Mayo Foundation, Rochester, Minnesota 55905, USA
    Anesthesiology 90:372-9. 1999
    ....
  15. ncbi request reprint So you want to be a pulmonary mechanic: a clinical guide
    D O Warner
    Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Clin Monit Comput 16:417-23. 2000
    ..A basic understanding of the principles involved will help prevent the misuse of this important information...
  16. ncbi request reprint Perioperative abstinence from cigarettes: physiologic and clinical consequences
    David O Warner
    Department of Anesthesiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Anesthesiology 104:356-67. 2006
    ..It will also consider current evidence regarding how nicotine replacement therapy, a valuable adjunct to help patients maintain abstinence, may affect perioperative physiology...
  17. doi request reprint Clinician-delivered intervention to facilitate tobacco quitline use by surgical patients
    David O Warner
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Anesthesiology 114:847-55. 2011
    ..This study developed and tested a clinician-delivered intervention to facilitate quitline use by adult patients scheduled for elective surgery...
  18. doi request reprint Smoking and pain: pathophysiology and clinical implications
    Yu Shi
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA
    Anesthesiology 113:977-92. 2010
    ....
  19. ncbi request reprint NO responsiveness in pulmonary artery and airway smooth muscle: the role of cGMP regulation
    Young L Kwak
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Am J Physiol Lung Cell Mol Physiol 290:L200-8. 2006
    ..An intrinsic smooth muscle mechanism accounting for greater NO responsiveness in PASM vs. TSM is greater sGC activity...
  20. ncbi request reprint Predictors of survival following cardiac arrest in patients undergoing noncardiac surgery: a study of 518,294 patients at a tertiary referral center
    Juraj Sprung
    Department of Anesthesiology, Division of Biostatistics, Mayo Clinic, Rochester, MN 55905, USA
    Anesthesiology 99:259-69. 2003
    ..The authors determined the incidence of cardiac arrest and predictors of survival following perioperative cardiac arrest in a large population of patients at a tertiary referral center...
  21. ncbi request reprint Postoperative outcome of patients with narcolepsy. A retrospective analysis
    Bethanie Burrow
    Department of Anesthesiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    J Clin Anesth 17:21-5. 2005
    ..To determine the postoperative outcome of narcolepsy patients, a population that may be at increased risk of perioperative complications, including postoperative hypersomnia, prolonged emergence after general anesthesia, and apnea...
  22. ncbi request reprint Differential effects of soluble and particulate guanylyl cyclase on Ca(2+) sensitivity in airway smooth muscle
    Edwin H Rho
    Department of Anesthesiology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    J Appl Physiol 92:257-63. 2002
    ..Thus, during muscarinic stimulation, stimulation of pGC relaxes ASM exclusively by decreasing [Ca(2+)](i), whereas stimulation of sGC decreases both [Ca(2+)](i) and Ca(2+) sensitivity...
  23. pmc Early exposure to anesthesia and learning disabilities in a population-based birth cohort
    Robert T Wilder
    Department of Anesthesiology, College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Anesthesiology 110:796-804. 2009
    ..The authors studied association between anesthetic exposure before age 4 yr and the development of reading, written language, and math learning disabilities (LD)...
  24. doi request reprint Perioperative tobacco interventions by Chinese anesthesiologists: practices and attitudes
    Yu Shi
    Department of Anesthesiology and Nicotine Research Center, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Anesthesiology 112:338-46. 2010
    ..However, little is known about the practices, knowledge, and attitudes of Chinese anesthesiologists regarding perioperative tobacco interventions...
  25. ncbi request reprint Reduction in soluble guanylyl cyclase-specific activity following prolonged treatment of porcine pulmonary artery with nitric oxide
    William J Perkins
    Department of Anesthesiology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
    Am J Physiol Lung Cell Mol Physiol 293:L84-95. 2007
    ..We conclude that prolonged NO treatment induces decreased acute NO responsiveness in part by decreasing both sGC expression and sGC-specific activity...
  26. ncbi request reprint Pain relief and functional status after vaginal hysterectomy: intrathecal versus general anesthesia
    Juraj Sprung
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Can J Anaesth 53:690-700. 2006
    ..We tested the hypothesis that the use of subarachnoid block (SAB) for vaginal hysterectomy produces superior postoperative analgesia and improves functional status at 12 weeks postoperatively...
  27. ncbi request reprint Efficacy of gabapentin in the management of chemotherapy-induced peripheral neuropathy: a phase 3 randomized, double-blind, placebo-controlled, crossover trial (N00C3)
    Ravi D Rao
    Department of Medical Oncology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Cancer 110:2110-8. 2007
    ..On the basis of these data, a multicenter, double-blind, placebo-controlled, crossover, randomized trial was conducted to evaluate the effect of gabapentin on symptoms of chemotherapy-induced peripheral neuropathy (CIPN)...
  28. ncbi request reprint Review article: age related alterations in respiratory function - anesthetic considerations
    Juraj Sprung
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Can J Anaesth 53:1244-57. 2006
    ....
  29. doi request reprint Obesity as a risk factor for unanticipated admissions after ambulatory surgery
    Roger E Hofer
    Department of Anesthesiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Mayo Clin Proc 83:908-16. 2008
    ..To test the hypothesis that obesity is an independent risk factor for unplanned hospital admission or readmission among patients scheduled for ambulatory surgery in a tertiary medical center...
  30. doi request reprint Effects of smoking status on immediate treatment outcomes of multidisciplinary pain rehabilitation
    W Michael Hooten
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Pain Med 10:347-55. 2009
    ..The primary aim of this study was to determine the effects of smoking on treatment outcomes following multidisciplinary pain rehabilitation. A secondary aim was to assess the tobacco use characteristics of smokers with chronic pain...
  31. ncbi request reprint An assessment of the association between smoking status, pain intensity, and functional interference in patients with chronic pain
    Toby N Weingarten
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    Pain Physician 11:643-53. 2008
    ..Current smoking is associated with less favorable clinical presentations...
  32. pmc Prolonged treatment of porcine pulmonary artery with nitric oxide decreases cGMP sensitivity and cGMP-dependent protein kinase specific activity
    William J Perkins
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Am J Physiol Lung Cell Mol Physiol 296:L121-9. 2009
    ..min(-1).ng cGKI(-1), respectively). We conclude that prolonged NO treatment induces decreased acute NO responsiveness in PA in part by decreasing cGMP sensitivity. It does so by decreasing both cGKI expression and cGKI specific activity...
  33. doi request reprint The effects of smoking status on opioid tapering among patients with chronic pain
    W Michael Hooten
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Anesth Analg 108:308-15. 2009
    ..Secondary aims included determining the associations between smoking status, admission opioid use, and pain severity...
  34. doi request reprint Impact of tobacco use on the symptoms of painful temporomandibular joint disorders
    Toby N Weingarten
    Department of Anesthesiology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    Pain 147:67-71. 2009
    ..These effects were more pronounced in cases where myofascial pain was not present...
  35. pmc The effects of depression and smoking on pain severity and opioid use in patients with chronic pain
    W Michael Hooten
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55902, USA
    Pain 152:223-9. 2011
    ..This study found that pain severity was associated with greater depression but not smoking; however, smoking was associated with greater opioid use, independent of depression...
  36. pmc Derivation and validation of automated electronic search strategies to identify pertinent risk factors for postoperative acute lung injury
    Anas Alsara
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 86:382-8. 2011
    ..To develop and validate time-efficient automated electronic search strategies for identifying preoperative risk factors for postoperative acute lung injury...
  37. doi request reprint Sex differences in characteristics of smokers with chronic pain undergoing multidisciplinary pain rehabilitation
    W Michael Hooten
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Pain Med 10:1416-25. 2009
    ..The primary aim of this study was to determine the influence of sex and the interactions between sex and smoking status on the immediate treatment outcomes of patients undergoing multidisciplinary pain treatment...
  38. ncbi request reprint Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer: a randomized controlled trial
    Gilbert Y Wong
    Department of Anesthesiology and Division of Pain Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
    JAMA 291:1092-9. 2004
    ..Pancreatic cancer is an aggressive tumor associated with high mortality. Optimal pain control may improve quality of life (QOL) for these patients...
  39. ncbi request reprint Recent smoking behavior and postoperative nausea and vomiting
    Francis Whalen
    Anesthesia Clinical Research Unit, Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA
    Anesth Analg 103:70-5, table of contents. 2006
    ..However, there was no correlation between preoperative CO and nausea over the first 24 h. These preliminary data suggest that the effect of smoking in reduced PONV is not directly related to preoperative exhaled CO levels...
  40. ncbi request reprint The diagnosis of obstructive sleep apnea as a risk factor for unanticipated admissions in outpatient surgery
    Candace Sabers
    Anesthesia Clinical Research Unit, Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA
    Anesth Analg 96:1328-35, table of contents. 2003
    ....
  41. ncbi request reprint The impact of morbid obesity, pneumoperitoneum, and posture on respiratory system mechanics and oxygenation during laparoscopy
    Juraj Sprung
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Anesth Analg 94:1345-50. 2002
    ..02). In conclusion, respiratory mechanics during laparoscopy are affected by obesity and pneumoperitoneum but vary little with body position. The PaO(2) was adversely affected only by increased body weight...
  42. ncbi request reprint Nitric oxide sensitivity in pulmonary artery and airway smooth muscle: a possible role for cGMP responsiveness
    Miwa Taniguchi
    Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Am J Physiol Lung Cell Mol Physiol 290:L1018-27. 2006
    ..A novel intrinsic smooth muscle mechanism accounting for greater NO responsiveness in PASM vs. TSM is thus greater cGMP responsiveness from increased cGKI-specific activity in PASM...
  43. ncbi request reprint Morbidity and mortality of deep sedation in outpatient bone marrow biopsy
    Christopher M Burkle
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Am J Hematol 77:250-6. 2004
    ..2.25%, P = 0.006). No other differences between the groups were found. Although the study was retrospective and nonrandomized, the results suggest that the use of deep sedation for outpatient BMBA is as safe as using local anesthesia...
  44. ncbi request reprint Outcomes of cardiopulmonary resuscitation and predictors of survival in patients undergoing coronary angiography including percutaneous coronary interventions
    Juraj Sprung
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Anesth Analg 102:217-24. 2006
    ..Patients who received CPR in the cardiac catheterization lab have a remarkably frequent survival to hospital discharge rate. Long-term survival of these patients is only minimally reduced...
  45. ncbi request reprint Intrathecal anesthesia and recovery from radical prostatectomy: a prospective, randomized, controlled trial
    Daniel R Brown
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Anesthesiology 100:926-34. 2004
    ..The authors tested the hypothesis that the addition of intrathecal analgesia to general anesthesia would improve long-term functional status and decrease pain in patients undergoing radical retropubic prostatectomy...
  46. ncbi request reprint Perioperative visual changes
    Mary E Warner
    Department of Anesthesiology, Mayo Foundation, Rochester, Minnesota 55905, USA
    Anesthesiology 96:855-9. 2002
    ..The goal of this project was to describe the frequency and natural history of perioperative changes in vision...
  47. ncbi request reprint Radical retropubic prostatectomy and blood transfusion
    Gregory A Nuttall
    Department of Anesthesiology, Mayo Clinic, Rochester, Minn 55905, USA
    Mayo Clin Proc 77:1301-5. 2002
    ....
  48. pmc Randomized, double-blinded, placebo controlled study of neuroprotection with lidocaine in cardiac surgery
    Joseph P Mathew
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Stroke 40:880-7. 2009
    ..Based on experimental and clinical evidence, this study assessed the potential of intravenously administered lidocaine to reduce postoperative cognitive dysfunction after cardiac surgery using cardiopulmonary bypass...
  49. ncbi request reprint Predictors of mortality following symptomatic pulmonary embolism in patients undergoing noncardiac surgery
    Thomas B Comfere
    Department of Anesthesiology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Can J Anaesth 54:634-41. 2007
    ..To determine 30-day mortality and predictors of mortality following perioperative pulmonary embolism (PE)...
  50. doi request reprint Tobacco intervention attitudes and practices among certified registered nurse anesthetists
    Chad S Houghton
    Department of Anesthesiology, Anesthesia Clinical Research Unit, Nicotine Research Center, Mayo Clinic, Rochester, Minnesota 55905, USA
    Nurs Res 57:123-9. 2008
    ..The period before surgery represents an opportunity for perioperative nurses, including certified registered nurse anesthetists (CRNAs), to address the tobacco use of their patients...
  51. ncbi request reprint Tobacco control for anesthesiologists
    David O Warner
    Department of Anesthesiology, the Anesthesia Clinical Research Unit, and the Nicotine Dependence Center, Mayo Clinic, Rochester, MN, USA
    J Anesth 21:200-11. 2007
    ..Anesthesiologists can play a key role in helping their patients quit smoking. Effective tobacco control measures applied to surgical patients will not only improve immediate perioperative outcomes but also long-term health...
  52. ncbi request reprint Perioperative cardiac arrests in children between 1988 and 2005 at a tertiary referral center: a study of 92,881 patients
    Randall P Flick
    Department of Anesthesiology, Mayo Clinic College of Medicine, MN 55905, USA
    Anesthesiology 106:226-37; quiz 413-4. 2007
    ..The objective of this study was to determine the incidence and outcome of perioperative cardiac arrest (CA) in children younger than 18 yr undergoing anesthesia for noncardiac and cardiac procedures at a tertiary care center...
  53. doi request reprint Comparison of two preoperative medical management strategies for laparoscopic resection of pheochromocytoma
    Toby N Weingarten
    Department of Anesthesiology and Anesthesia Clinical Research Unit, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Urology 76:508.e6-11. 2010
    ..However, no consensus has been reached regarding the best preoperative preparation regimen...
  54. ncbi request reprint The effects of the alveolar recruitment maneuver and positive end-expiratory pressure on arterial oxygenation during laparoscopic bariatric surgery
    Francis X Whalen
    Department of Anesthesiology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Anesth Analg 102:298-305. 2006
    ..Our results showed the effect to be short lived and associated with more frequent intraoperative use of vasopressors...
  55. ncbi request reprint The effects of hexanol on Galpha(i) subunits of heterotrimeric G proteins
    John Streiff
    Departments of Anesthesiology and Physiology and Biophysics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Anesth Analg 98:660-7, table of contents. 2004
    ..This finding implies that this is not a mechanism by which hexanol interferes with receptor-G protein function...
  56. doi request reprint Alveolar recruitment and arterial desflurane concentration during bariatric surgery
    Juraj Sprung
    Department of Anesthesiology, College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Anesth Analg 108:120-7. 2009
    ..We investigated whether reversal of intraoperative atelectasis with the lung recruitment maneuver (RM) affects desflurane arterial concentrations during bariatric surgery...
  57. ncbi request reprint Differential effects of volatile anesthetics on M3 muscarinic receptor coupling to the Galphaq heterotrimeric G protein
    Tetsuzo Nakayama
    Department of Anesthesiology, Mayo Foundation, Rochester, Minnesota 55905, USA
    Anesthesiology 105:313-24. 2006
    ....
  58. pmc Anesthesia for cesarean delivery and learning disabilities in a population-based birth cohort
    Juraj Sprung
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA
    Anesthesiology 111:302-10. 2009
    ..The association between perinatal exposure to anesthetics during Cesarean delivery (CD) and development of learning disabilities (LD) was determined in a population-based birth cohort...
  59. doi request reprint Bronchospasm after intravenous lidocaine
    Bobby R Burches
    Department of Anesthesiology, Mayo Clinic, 200 1st St SW, Rochester, MN 55905, USA
    Anesth Analg 107:1260-2. 2008
    ..This is consistent with recent clinical studies suggesting that IV lidocaine may cause airway narrowing in asthmatics. Practitioners should be aware of this potential complication...
  60. pmc Effects of smoking cessation on pain in older adults
    Yu Shi
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    Nicotine Tob Res 13:919-25. 2011
    ..The aim of this study was to determine the association between smoking cessation and changes in pain symptoms by secondary analysis of a large longitudinal dataset of older adults...
  61. ncbi request reprint Succinylcholine and the open globe. Tracing the teaching
    Claude A Vachon
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Anesthesiology 99:220-3. 2003
  62. ncbi request reprint Dual effects of hexanol and halothane on the regulation of calcium sensitivity in airway smooth muscle
    Hayashi Yoshimura
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Anesthesiology 98:871-80. 2003
    ..The authors tested the hypothesis that hexanol, like halothane, inhibits agonist-induced increases in calcium sensitivity in airway smooth muscle by inhibiting G-protein pathways...
  63. ncbi request reprint Anesthetics inhibit acetylcholine-promoted guanine nucleotide exchange of heterotrimeric G proteins of airway smooth muscle
    Chie Sakihara
    Department of Anesthesiology, Mayo Foundation, Rochester, Minnesota 55905, USA
    Anesthesiology 101:120-6. 2004
    ..e., they inhibit muscarinic receptor-Galphaq/11 coupling)...
  64. ncbi request reprint Angiotensin system inhibitors in a general surgical population
    Thomas Comfere
    Department of Anesthesiology, Mayo Clinic College of Medicine, 200 First St S W, Rochester, MN 55905, USA
    Anesth Analg 100:636-44, table of contents. 2005
    ..No differences in postoperative complications were found between groups. In conclusion, discontinuation of ACEI/ARA therapy at least 10 h before anesthesia was associated with a reduced risk of immediate postinduction hypotension...
  65. ncbi request reprint Anesthetics inhibit membrane receptor coupling to the Gq/11 heterotrimeric G protein in airway smooth muscle
    Tetsuzo Nakayama
    Department of Anesthesiology, Mayo Foundation, Rochester, Minnesota 55905, USA
    Anesthesiology 103:296-305. 2005
    ..This study tested the hypothesis that these anesthetic effects are not unique to the muscarinic receptor but are a general property of the heptahelical receptors that increase Ca2+ sensitivity in airway smooth muscle...
  66. doi request reprint Intraoperative extracorporeal membrane oxygenation and survival of pediatric patients undergoing repair of congenital heart disease
    Randall P Flick
    Department of Anesthesiology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Paediatr Anaesth 18:757-66. 2008
    ..We compare two periods, before formal introduction of ECMO in our institution (1993-1999, pre-ECMO era) and after ECMO became a formalized program (2000-2006, ECMO era)...
  67. ncbi request reprint Halothane does not inhibit the functional coupling between the beta2-adrenergic receptor and the Galphas heterotrimeric G protein
    Masao Hayashi
    Department of Anesthesiology, Mayo Foundation, Rochester, Minnesota 55905, USA
    Anesthesiology 104:754-62. 2006
    ..The authors hypothesized that halothane does not affect isoproterenol-promoted guanosine nucleotide exchange at Galphas and hence would not affect isoproterenol-induced relaxation of airway smooth muscle...
  68. ncbi request reprint Prolonged relaxation consistent with persistent soluble guanylyl cyclase activation in canine pulmonary artery following brief treatment with nitric oxide donors
    Young L Kwak
    Department of Anesthesia and Pain Medicine, Yonsei University College of Medicine, Republic of Korea
    Life Sci 79:2001-9. 2006
    ..Reversal of this cGMP-dependent process with DTT suggests that it occurs via mechanisms that are thiol redox sensitive...
  69. ncbi request reprint Preoperative smoking cessation: how long is long enough?
    David O Warner
    Anesthesiology 102:883-4. 2005
  70. ncbi request reprint Long-haul air travel before major surgery: a prescription for thromboembolism?
    Ognjen Gajic
    Department of Internal Medicine and Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 80:728-31. 2005
    ..To investigate the Incidence of postoperative venous thromboembolism (VTE) in patients who had flown long distances before major surgery...
  71. ncbi request reprint Diaphragm function during anesthesia: still crazy after all these years
    David O Warner
    Anesthesiology 97:295-7. 2002
  72. ncbi request reprint Are pharmaceutical representatives reliable guides to the medical literature?
    David O Warner
    Anesth Analg 96:1837; author reply 1837. 2003
  73. ncbi request reprint Effects of primary alcohols on airway smooth muscle
    Chie Sakihara
    Department of Anesthesiology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Anesthesiology 96:428-37. 2002
    ....
  74. ncbi request reprint Parenteral vs epidural analgesia for postoperative pain
    Christopher J Jankowski
    JAMA 291:1197-8; author reply 1198. 2004

Research Grants16

  1. ANANESTHESIA AND AIRWAYS
    David Warner; Fiscal Year: 2001
    ..In these preparations, calcium levels can be controlled, and membrane receptor second messenger systems that alter calcium sensitivity are intact. ..
  2. ANANESTHESIA AND AIRWAYS
    David Warner; Fiscal Year: 2000
    ..In these preparations, calcium levels can be controlled, and membrane receptor second messenger systems that alter calcium sensitivity are intact. ..
  3. ANANESTHESIA AND AIRWAYS
    David Warner; Fiscal Year: 1999
    ..In these preparations, calcium levels can be controlled, and membrane receptor second messenger systems that alter calcium sensitivity are intact. ..
  4. ANESTHESIA AND AIRWAYS
    David Warner; Fiscal Year: 1993
    ..This may cause increased VA/Q mismatch during anesthesia. We wish to test our hypothesis that injectable anesthetics may interfere less with hypocapnic bronchoconstriction than volatile anesthetics...
  5. ANESTHESIA AND AIRWAYS
    David Warner; Fiscal Year: 1992
    ..This may cause increased VA/Q mismatch during anesthesia. We wish to test our hypothesis that injectable anesthetics may interfere less with hypocapnic bronchoconstriction than volatile anesthetics...
  6. ANESTHESIA AND AIRWAYS
    David Warner; Fiscal Year: 1991
    ..This may cause increased VA/Q mismatch during anesthesia. We wish to test our hypothesis that injectable anesthetics may interfere less with hypocapnic bronchoconstriction than volatile anesthetics...
  7. ANESTHESIA AND AIRWAYS
    David Warner; Fiscal Year: 1990
    ..This may cause increased VA/Q mismatch during anesthesia. We wish to test our hypothesis that injectable anesthetics may interfere less with hypocapnic bronchoconstriction than volatile anesthetics...
  8. Elective Surgery as a Teachable Moment for Smoking Cessation
    David Warner; Fiscal Year: 2007
    ..Our overall goal is to develop effective tobacco use interventions for surgical patients; this project will be an important step in this process. ..