Research Topics
Genomes and GenesSpecies | C Vilariño-GüellSummaryAffiliation: Mayo Clinic Country: USA Publications
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Detail Information
Publications
Characterization of DCTN1 genetic variability in neurodegenerationC Vilariño-Güell
Molecular Genetics Laboratory and Core, Morris K Udall Parkinson s Disease Research Center of Excellence, Mayo Clinic, Department of Neuroscience, 4500 San Pablo Road, Jacksonville, FL 32224, USA
Neurology 72:2024-8. 2009....
LINGO1 rs9652490 is associated with essential tremor and Parkinson diseaseCarles Vilariño-Güell
Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA
Parkinsonism Relat Disord 16:109-11. 2010..Our study demonstrates a significant association between LINGO1 rs9652490 and essential tremor (P = 0.014) and Parkinson disease (P = 0.0003), thus providing the first evidence of a genetic link between both diseases...
Association of the MAPT locus with Parkinson's diseaseC Wider
Department of Neuroscience, Mayo Clinic, Molecular Genetics Laboratory and Core, Morris K Udall Parkinsons Disease Research Center of Excellence, Jacksonville, FL 32224, USA
Eur J Neurol 17:483-6. 2010..Whilst an association between the tau gene (MAPT)-containing H1 haplotype and supranuclear gaze palsy (PSP) has long been recognized, the effect of H1 on risk for Parkinson's disease (PD) has remained more contentious...
Death-associated protein kinase 1 variation and Parkinson's diseaseJ C Dachsel
Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA
Eur J Neurol 18:1090-3. 2011..The Lrrk2 protein is a member of the ROCO family, which also includes Lrrk1 and Dapk1. Functional genetic variants of the DAPK1 gene (rs4877365 and rs4878104) have been previously associated with Alzheimer's disease...
SNCA, MAPT, and GSK3B in Parkinson disease: a gene-gene interaction studyC Wider
Division of Neurogenetics, Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA
Eur J Neurol 18:876-81. 2011..In the current study, we attempt to validate previously published findings, evaluating gene-gene interactions between SNCA, MAPT, and GSK3B in association with PD...
Susceptibility genes for restless legs syndrome are not associated with Parkinson diseaseC Vilariño-Güell
Department of Neuroscience, Division of Neurogenetics, Mayo Clinic, Jacksonville, FL 32224, USA
Neurology 71:222-3. 2008
Calbindin-1 association and Parkinson's diseaseA I Soto-Ortolaza
Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL, USA
Eur J Neurol 17:208-11. 2010..Recently, an association was reported between the calcium buffer, calbindin (rs1805874) and risk of PD in a Japanese patient-control series...
A family with Parkinsonism, essential tremor, restless legs syndrome, and depressionA Puschmann
Department of Neurology, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL 32224, USA
Neurology 76:1623-30. 2011..Previous epidemiologic and genetic studies have suggested a link between Parkinson disease (PD), essential tremor (ET), and restless legs syndrome (RLS)...
A comparative study of LRRK2, PINK1 and genetically undefined familial Parkinson's diseaseKenya Nishioka
Division of Neurogenetics, Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA
J Neurol Neurosurg Psychiatry 81:391-5. 2010..As future therapies are targeted to specific protein abnormalities, identifying the genetic causes and associated clinical and pathological features will determine diagnosis, preventative medicine and drug intervention strategies...
