CELINE M contact VACHON

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. pmc Mammographic breast density response to aromatase inhibition
    Celine M Vachon
    Department of Health Sciences, Mayo Clinic College of Medicine, Rochester, Minnesota, 55905, USA
    Clin Cancer Res 19:2144-53. 2013
  2. pmc No evidence for association of inherited variation in genes involved in mitosis and percent mammographic density
    Celine M Vachon
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Breast Cancer Res 14:R7. 2012
  3. pmc A novel automated mammographic density measure and breast cancer risk
    John J Heine
    Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    J Natl Cancer Inst 104:1028-37. 2012
  4. pmc Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study
    Roger L Milne
    Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre CNIO, Madrid, 28029, Spain
    Breast Cancer Res 12:R110. 2010
  5. pmc Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer
    Jingmei Li
    Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden
    Breast Cancer Res 12:R19. 2010
  6. pmc Linkage analysis of obesity phenotypes in pre- and post-menopausal women from a United States mid-western population
    Linda E Kelemen
    Department of Population Health Research, Alberta Health Services Cancer Care, Calgary, AB, Canada
    BMC Med Genet 11:156. 2010
  7. pmc Mammographic density, breast cancer risk and risk prediction
    Celine M Vachon
    Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Breast Cancer Res 9:217. 2007
  8. ncbi request reprint Mammographic breast density as a general marker of breast cancer risk
    Celine M Vachon
    Mayo Clinic College of Medicine, Charlton 6 239, 200 First Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 16:43-9. 2007
  9. ncbi request reprint Strong evidence of a genetic determinant for mammographic density, a major risk factor for breast cancer
    Celine M Vachon
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Cancer Res 67:8412-8. 2007
  10. ncbi request reprint Pilot study of the impact of letrozole vs. placebo on breast density in women completing 5 years of tamoxifen
    C M Vachon
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, USA
    Breast 16:204-10. 2007

Research Grants

  1. Risk factors for breast cancer molecular subtypes
    CELINE M contact VACHON; Fiscal Year: 2010
  2. Identifying Genes for Mammographic Breast Density
    Celine M Vachon; Fiscal Year: 2010
  3. Identifying Genes for Mammographic Breast Density
    Celine Vachon; Fiscal Year: 2009
  4. A Mayo Cohort Study of Mammographic Breast Density
    Celine Vachon; Fiscal Year: 2007
  5. Identifying Genes for Mammographic Breast Density
    Celine Vachon; Fiscal Year: 2009

Detail Information

Publications66

  1. pmc Mammographic breast density response to aromatase inhibition
    Celine M Vachon
    Department of Health Sciences, Mayo Clinic College of Medicine, Rochester, Minnesota, 55905, USA
    Clin Cancer Res 19:2144-53. 2013
    ..Mammographic breast density (MBD) is decreased by tamoxifen, but the effect of aromatase inhibitors is less clear...
  2. pmc No evidence for association of inherited variation in genes involved in mitosis and percent mammographic density
    Celine M Vachon
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Breast Cancer Res 14:R7. 2012
    ....
  3. pmc A novel automated mammographic density measure and breast cancer risk
    John J Heine
    Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    J Natl Cancer Inst 104:1028-37. 2012
    ..We developed an automated and objective measurement of the grayscale value variation within a mammogram, evaluated its association with breast cancer, and compared its performance with that of percent density (PD)...
  4. pmc Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study
    Roger L Milne
    Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre CNIO, Madrid, 28029, Spain
    Breast Cancer Res 12:R110. 2010
    ....
  5. pmc Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer
    Jingmei Li
    Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden
    Breast Cancer Res 12:R19. 2010
    ..In this study, we evaluate the association between mammographic density and genetic variants of the estrogen metabolic pathway...
  6. pmc Linkage analysis of obesity phenotypes in pre- and post-menopausal women from a United States mid-western population
    Linda E Kelemen
    Department of Population Health Research, Alberta Health Services Cancer Care, Calgary, AB, Canada
    BMC Med Genet 11:156. 2010
    ..Women are also more likely to distribute weight in the abdomen following menopause. We investigated whether genetic loci link with obesity-related phenotypes differently by menopausal status...
  7. pmc Mammographic density, breast cancer risk and risk prediction
    Celine M Vachon
    Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Breast Cancer Res 9:217. 2007
    ..Promising new measures of mammographic density, including volumetric density, which can be standardized using full-field digital mammography, will likely result in a stronger risk factor and improve accuracy of risk prediction models...
  8. ncbi request reprint Mammographic breast density as a general marker of breast cancer risk
    Celine M Vachon
    Mayo Clinic College of Medicine, Charlton 6 239, 200 First Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 16:43-9. 2007
    ..Overall mammographic density seems to represent a general marker of breast cancer risk that is not specific to breast side or location of the eventual cancer...
  9. ncbi request reprint Strong evidence of a genetic determinant for mammographic density, a major risk factor for breast cancer
    Celine M Vachon
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Cancer Res 67:8412-8. 2007
    ..4 cM). The putative locus on chromosome 5p is likely to account for up to 22% of variation in MD. Hence, 1 or more of the 45 candidate genes in this region could explain a large proportion of MD and, potentially, breast cancer...
  10. ncbi request reprint Pilot study of the impact of letrozole vs. placebo on breast density in women completing 5 years of tamoxifen
    C M Vachon
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, USA
    Breast 16:204-10. 2007
    ..Results were similar for longitudinal change (-0.68% per year, LET; -0.12% per year, PLAC (P=0.23)). Breast density does not appear to be a clinically relevant biomarker in women who already have low PD following 5 years of TAM...
  11. pmc Increased risk of monoclonal gammopathy in first-degree relatives of patients with multiple myeloma or monoclonal gammopathy of undetermined significance
    Celine M Vachon
    Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Blood 114:785-90. 2009
    ..0; 95% CI, 1.4 to 2.8) and MGUS probands (RR, 3.3; 95% CI, 2.1 to 4.8). The increased risk of MGUS in first-degree relatives of MGUS or MM patients implies shared environment and/or genetics...
  12. pmc Aromatase immunoreactivity is increased in mammographically dense regions of the breast
    Celine M Vachon
    Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Breast Cancer Res Treat 125:243-52. 2011
    ..45, SD = 0.39) breast tissue (β(H) = 0.45; P < 0.001). Overall, aromatase IR was greater for mammographically dense versus non-dense tissue and may partly explain how MBD influences breast cancer...
  13. ncbi request reprint Alcohol intake in adolescence and mammographic density
    Celine M Vachon
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Int J Cancer 117:837-41. 2005
    ..0-23.4%). However, these associations were not statistically significant (p = 0.27 and p = 0.22, respectively). In summary, there was no evidence that adolescent alcohol use was associated with large and persistent effects on adult PD...
  14. pmc Novel breast tissue feature strongly associated with risk of breast cancer
    Kevin P McKian
    Department of Oncology, Mayo Clinic Cancer Center, Mayo Graduate School of Medical Education, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Clin Oncol 27:5893-8. 2009
    ..Breast lobules are the anatomic sites of origin of breast cancer. As women age, these lobular structures should regress, which results in reduced breast cancer risk. However, this does not occur in all women...
  15. pmc Association between mammographic density and age-related lobular involution of the breast
    Karthik Ghosh
    Division of General Internal Medicine, Department of Internal Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    J Clin Oncol 28:2207-12. 2010
    ..We examined the involution and density association in a large benign breast disease (BBD) cohort...
  16. ncbi request reprint Age-related lobular involution and risk of breast cancer
    Tia R Milanese
    Mayo Medical School, Rochester, MN 55905, USA
    J Natl Cancer Inst 98:1600-7. 2006
    ..As women age, the lobules in their breasts undergo involution or regression. We investigated whether lobular involution in women with benign breast disease was associated with subsequent breast cancer risk...
  17. doi request reprint Age-specific trends in mammographic density: the Minnesota Breast Cancer Family Study
    Linda E Kelemen
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Am J Epidemiol 167:1027-36. 2008
    ..These data suggest that menopause, baseline PD, postmenopausal hormone use, and body mass index predict changes in mammographic density trends during adult life...
  18. ncbi request reprint Does folate intake decrease risk of postmenopausal breast cancer among women with a family history?
    Thomas A Sellers
    Mayo Clinic Cancer Center, Rochester, MN 55905, USA
    Cancer Causes Control 15:113-20. 2004
    ..We examined whether the putative benefit extends to women with a family history (FH) of breast cancer using a cohort of 33,552 postmenopausal women aged 55-69 years in 1986...
  19. ncbi request reprint Association of aspirin and nonaspirin nonsteroidal anti-inflammatory drugs with cancer incidence and mortality
    Aditya Bardia
    Department of Internal Medicine, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
    J Natl Cancer Inst 99:881-9. 2007
    ..We evaluated associations between aspirin and nonaspirin NSAID use with cancer incidence and mortality stratified by smoking history in the Iowa Women's Health Study, a prospective cohort of postmenopausal women...
  20. ncbi request reprint Postmenopausal cancer risk after self-reported endometriosis diagnosis in the Iowa Women's Health Study
    Janet E Olson
    Mayo Foundation, Health Sciences Research, Rochester, Minnesota 55905, USA
    Cancer 94:1612-8. 2002
    ..A recent study reported that women with a hospital discharge diagnosis of endometriosis were at increased risk of cancer at any site, breast cancer, ovarian cancer, and hematopoietic malignancies, especially non-Hodgkin lymphoma (NHL)...
  21. ncbi request reprint Benign breast disease and the risk of breast cancer
    Lynn C Hartmann
    Division of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    N Engl J Med 353:229-37. 2005
    ..Benign breast disease is an important risk factor for breast cancer. We studied a large group of women with benign breast disease to obtain reliable estimates of this risk...
  22. pmc Relative weight at age 12 and risk of postmenopausal breast cancer
    Aditya Bardia
    Department of Internal Medicine, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 17:374-8. 2008
    ....
  23. pmc Association of genetic variation in genes implicated in the beta-catenin destruction complex with risk of breast cancer
    Xianshu Wang
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Stabile 2 42, 200 First Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 17:2101-8. 2008
    ....
  24. ncbi request reprint Recreational physical activity and risk of postmenopausal breast cancer based on hormone receptor status
    Aditya Bardia
    Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Arch Intern Med 166:2478-83. 2006
    ..The objective of this study was to examine the association of physical activity with breast cancer incidence based on ER/PR status of the tumor...
  25. pmc Texture features from mammographic images and risk of breast cancer
    Armando Manduca
    Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 1st Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 18:837-45. 2009
    ..However, simultaneous inclusion of these features in a model with PD did not significantly improve the ability to predict breast cancer...
  26. ncbi request reprint Menstrual and reproductive factors and risk of non-Hodgkin lymphoma: the Iowa women's health study (United States)
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Cancer Causes Control 13:131-6. 2002
    ..Endogenous sex hormones, particularly estrogens, modulate the immune system, and non-Hodgkin lymphoma (NHL) is a tumor that is related to immunologic status...
  27. ncbi request reprint Prenatal and perinatal correlates of adult mammographic breast density
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 14:1502-8. 2005
    ..We examined the hypothesis that those factors associated with higher levels of estrogen during pregnancy or shortly after birth are associated with higher mammographic breast density in adulthood...
  28. pmc Assessment of the accuracy of the Gail model in women with atypical hyperplasia
    V Shane Pankratz
    Division of Biostatistics, Medical Oncology, General Surgery, Internal Medicine, Epidemiology, and Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 26:5374-9. 2008
    ..Women with biopsy-confirmed atypical hyperplasia of the breast (atypia) are at high risk for breast cancer. The Gail model is widely used in these women, but has not been validated in them...
  29. ncbi request reprint Clinical characteristics of familial vs. sporadic non-Hodgkin lymphoma in patients diagnosed at the Mayo Clinic (1986-2000)
    Celine M Vachon
    Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Leuk Lymphoma 45:929-35. 2004
    ..none (50%) (P = 0.20). We found little evidence of large differences between familial and sporadic NHL with regard to age, gender, site or histologic subtype...
  30. ncbi request reprint Interaction of adolescent anthropometric characteristics and family history on breast cancer risk in a Historical Cohort Study of 426 families (USA)
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Cancer Causes Control 15:1-9. 2004
    ..To determine whether the association of adolescent anthropometric characteristics with breast cancer is modified by a family history of the disease...
  31. pmc Healthy women's motivators and barriers to participation in a breast cancer cohort study: a qualitative study
    Pamela S Sinicrope
    Behavioral Health Program, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Ann Epidemiol 19:484-93. 2009
    ..These women would then be followed up long term for breast cancer incidence and mortality...
  32. ncbi request reprint Association of aspirin and other non-steroidal anti-inflammatory drug use with incidence of non-Hodgkin lymphoma
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Int J Cancer 106:784-8. 2003
    ..These data suggest that use of NSAIDs, either aspirin or other non-aspirin NSAIDs, are associated positively with risk of NHL, and that this association is independent of RA history...
  33. ncbi request reprint High-folate diets and breast cancer survival in a prospective cohort study
    Thomas A Sellers
    Department of Health Sciences Research, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, MN 55905, USA
    Nutr Cancer 44:139-44. 2002
    ..These findings, although preliminary, afford some reassurance that folate supplementation is unlikely to have a significant adverse effect on survival after chemotherapy for breast cancer...
  34. pmc Genetic susceptibility variants for chronic lymphocytic leukemia
    Susan L Slager
    Mayo Clinic College of Medicine, 200 1st Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 19:1098-102. 2010
    ..A recent genome-wide association study of CLL identified seven genetic variants that increased the risk of CLL within a European population...
  35. ncbi request reprint Association of parity and ovarian cancer risk by family history of breast or ovarian cancer in a population-based study of postmenopausal women
    Celine M Vachon
    Department of Health Sciences Research, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    Epidemiology 13:66-71. 2002
    ..Nulliparity may be more strongly associated with an increased risk of ovarian cancer among women with a family history of breast or ovarian cancer, compared with women who do not have a family history of those cancers...
  36. ncbi request reprint Hormone replacement therapy and risk of non-hodgkin lymphoma and chronic lymphocytic leukemia
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 11:1466-71. 2002
    ..For diffuse NHL, 64% of the cases were nodal, and there was no association of HRT with either nodal or extra-nodal sites. These data suggest that HRT is a risk factor for follicular NHL but not for diffuse or small lymphocyte NHL or CLL...
  37. pmc Independent association of lobular involution and mammographic breast density with breast cancer risk
    Karthik Ghosh
    Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Natl Cancer Inst 102:1716-23. 2010
    ..Lobular involution, or age-related atrophy of breast lobules, is inversely associated with breast cancer risk, and mammographic breast density (MBD) is positively associated with breast cancer risk...
  38. ncbi request reprint Interaction of dietary folate intake, alcohol, and risk of hormone receptor-defined breast cancer in a prospective study of postmenopausal women
    Thomas A Sellers
    Department of Health Sciences Research, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 11:1104-7. 2002
    ....
  39. ncbi request reprint Anthropometric characteristics, physical activity, and risk of non-Hodgkin's lymphoma subtypes and B-cell chronic lymphocytic leukemia: a prospective study
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Am J Epidemiol 156:527-35. 2002
    ..The opposite associations of body mass index with small lymphocytic lymphoma versus B-CLL may be a chance finding but, if confirmed, would suggest different etiologies for these malignancies...
  40. pmc Malignant melanoma in the 21st century: the emerging molecular landscape
    Aleksandar Sekulic
    Department of Dermatology, Mayo Clinic, Scottsdale, AZ 85259, USA
    Mayo Clin Proc 83:825-46. 2008
    ..We review the emerging molecular landscape of melanoma and its implications for better management of patients with melanoma...
  41. pmc Association of mammographic density with the pathology of subsequent breast cancer among postmenopausal women
    Karthik Ghosh
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 17:872-9. 2008
    ..Limited studies have examined the associations between mammographic density and subsequent breast tumor characteristics...
  42. ncbi request reprint Prepregnancy exposure to cigarette smoking and subsequent risk of postmenopausal breast cancer
    Janet E Olson
    Division of Epidemiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 80:1423-8. 2005
    ..To examine the association of cigarette smoking before first pregnancy with risk of postmenopausal breast cancer in a large population-based cohort...
  43. ncbi request reprint Longitudinal trends in mammographic percent density and breast cancer risk
    Celine M Vachon
    Mayo Clinic College of Medicine, Charlton 6 239, 200 First Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 16:921-8. 2007
    ..Mammographic density is a strong risk factor for breast cancer. However, whether changes in mammographic density are associated with risk remains unclear...
  44. ncbi request reprint Case-control study of increased mammographic breast density response to hormone replacement therapy
    Celine M Vachon
    Department of Health Sciences Research, Mayo Clinic Cancer Center, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 11:1382-8. 2002
    ..Because all risk factors examined accounted for only 26% of the variation in the HRT response, genes or other unmeasured factors are thought to be involved...
  45. doi request reprint Breast cancer risk in women with radial scars in benign breast biopsies
    Jena C Berg
    Department of Laboratory Medicine and Pathology, Division of Anatomic Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Breast Cancer Res Treat 108:167-74. 2008
    ..We studied the relative risk of radial scar lesions in a large cohort of patients with benign breast disease (BBD)...
  46. ncbi request reprint A comprehensive examination of CYP19 variation and breast density
    Janet E Olson
    Division of Epidemiology, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, MN 55901, USA
    Cancer Epidemiol Biomarkers Prev 16:623-5. 2007
  47. pmc A comprehensive examination of CYP19 variation and risk of breast cancer using two haplotype-tagging approaches
    Janet E Olson
    Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic College of Medicine, Rochester, MN 55901, USA
    Breast Cancer Res Treat 102:237-47. 2007
    ..We recently published resequencing data on 88 polymorphisms identified in that gene. The hypothesis tested in this study was that polymorphisms, or haplotypes, in CYP19 are related to risk of breast cancer...
  48. ncbi request reprint Susceptibility genes and B-chronic lymphocytic leukaemia
    Susan L Slager
    Division of Biostatistics, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, USA
    Br J Haematol 139:762-71. 2007
    ..The challenge of future studies of this type will be overcoming study design issues, including definition of CLL, sample size limitations and multiple testing issues...
  49. pmc Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL
    Susan L Slager
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Blood 117:1911-6. 2011
    ..Our findings support the hypothesis that familial CLL cases have additional genetic variants not seen in sporadic CLL. Additional loci among familial CLL cases may be identified through larger studies...
  50. doi request reprint Palpable presentation of breast cancer persists in the era of screening mammography
    Kellie L Mathis
    Department of Surgery, Mayo Clinic and Mayo Foundation, Rochester, MN, USA
    J Am Coll Surg 210:314-8. 2010
    ..The aim was to describe cancer detection method and frequency of screening mammography in women undergoing breast cancer surgery in 2000...
  51. pmc Factors associated with breast cancer prevention communication between mothers and daughters
    Pamela S Sinicrope
    Behavioral Health Program, Mayo Clinic Rochester College of Medicine, Rochester, Minnesota 55905, USA
    J Womens Health (Larchmt) 17:1017-23. 2008
    ..We examined the degree to which mothers reported providing advice on breast cancer prevention to their daughters, the content of such advice, and correlates of providing such advice...
  52. pmc Lobular involution: localized phenomenon or field effect?
    Robert A Vierkant
    Mayo Clinic Cancer Center, Rochester, MN, USA
    Breast Cancer Res Treat 117:193-6. 2009
    ..75, 95% CI 0.59, 0.89). Our study suggests that lobular involution is a homogeneous process, supporting the use of involution measures from a single benign biopsy as a component in breast cancer risk assessment paradigms...
  53. ncbi request reprint Efficacy of a simple, low-cost educational intervention in improving knowledge about risks and benefits of screening mammography
    Caroline P Haakenson
    Mayo Medical School, Rochester, Minn 55905, USA
    Mayo Clin Proc 81:783-91. 2006
    ..To assess the efficacy of a minimal cost and involvement educational intervention in improving women's knowledge about screening mammography and to explore patient perceptions of the educational intervention...
  54. pmc Adult daughters' reports of breast cancer risk reduction and early detection advice received from their mothers: an exploratory study
    Pamela S Sinicrope
    Mayo Clinic, College of Medicine, Behavioral Science Research, Rochester, MN 55901, USA
    Psychooncology 18:169-78. 2009
    ..Using survey data from 2328 women (mean age 62.5 years) from 372 families enrolled in the Minnesota breast cancer family study, we explored adult daughter's reports of breast cancer risk reduction advice received from their mothers...
  55. ncbi request reprint Malignant melanoma in the 21st century, part 1: epidemiology, risk factors, screening, prevention, and diagnosis
    Svetomir N Markovic
    Division of Hematology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
    Mayo Clin Proc 82:364-80. 2007
    ..Part 2 (which will appear in the April 2007 issue) will review melanoma staging, prognosis, and treatment...
  56. ncbi request reprint Incidence of basal cell and squamous cell carcinomas in a population younger than 40 years
    Leslie J Christenson
    Department of Dermatology, Mayo Clinic, Rochester, Minn 55905, USA
    JAMA 294:681-90. 2005
    ..The incidence of nonmelanoma skin cancer is increasing rapidly among elderly persons, but little is known about its incidence in the population younger than 40 years...
  57. ncbi request reprint Malignant melanoma in the 21st century, part 2: staging, prognosis, and treatment
    Svetomir N Markovic
    Division of Hematology, College of Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Mayo Clin Proc 82:490-513. 2007
    ..Although much work remains to be done to improve the survival of patients with melanoma, clinically meaningful results seem within reach...
  58. pmc Evidence of systemic Th2-driven chronic inflammation in patients with metastatic melanoma
    Wendy K Nevala
    Division of Hematology, Department of Internal Medicine, Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA
    Clin Cancer Res 15:1931-9. 2009
    ..To understand this discrepancy, we attempted to define immune homeostasis of 209 patients with melanoma across stages of disease relative to normal controls...
  59. ncbi request reprint Mammographic density of the breast
    Celine M Vachon
    N Engl J Med 348:174-5; author reply 174-5. 2003
  60. ncbi request reprint Association of diabetes with mammographic breast density and breast cancer in the Minnesota breast cancer family study
    Thomas A Sellers
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA
    Cancer Causes Control 18:505-15. 2007
    ..Our findings suggest that breast cancer risk may be increased among women with type II diabetes, but that type II diabetes does not significantly influence mammographic breast density...
  61. ncbi request reprint Preventive health behaviors and familial breast cancer
    Lisa Madlensky
    University of California San Diego Cancer Center, 9500 Gilman Drive, La Jolla, CA 92093 0901, USA
    Cancer Epidemiol Biomarkers Prev 14:2340-5. 2005
    ..To examine medical and lifestyle preventive behaviors among women with varying levels of familial breast cancer risk...
  62. pmc Can genes for mammographic density inform cancer aetiology?
    Linda E Kelemen
    Department of Population Health Research, Alberta Cancer Board, 1, 331 29th Street North West, Calgary, Alberta T2N 4N2, Canada
    Nat Rev Cancer 8:812-23. 2008
    ..In this Perspective, we review the limited genetic studies of MD and propose future directions...
  63. doi request reprint Dietary patterns and breast density in the Minnesota Breast Cancer Family Study
    Marilyn Tseng
    Division of Population Science, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA, 19111, USA
    Cancer Causes Control 19:481-9. 2008
    ..Whether dietary patterns, rather than single foods or nutrients, are associated with breast density is not known. We investigated this in the Minnesota Breast Cancer Family Study...
  64. ncbi request reprint No association between 25-hydroxyvitamin D and mammographic density
    Julia A Knight
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 5th Floor, 60 Murray Street, Toronto, Ontario, Canada M5G 1X5
    Cancer Epidemiol Biomarkers Prev 15:1988-92. 2006
    ..Unlike some previous reports, vitamin D does not seem to be related to mammographic density in this cohort...
  65. pmc Allergic pulmonary inflammation promotes the recruitment of circulating tumor cells to the lung
    Anna G Taranova
    Department of Biochemistry and Molecular Biology, Divisions of Pulmonary Medicine, Mayo Clinic Arizona, Scottsdale, Arizona 85259, USA
    Cancer Res 68:8582-9. 2008
    ....
  66. ncbi request reprint Genetic epidemiology of melanoma: of consortia and conundrums
    Gloria M Petersen
    J Natl Cancer Inst 94:872-3. 2002

Research Grants10

  1. Risk factors for breast cancer molecular subtypes
    CELINE M contact VACHON; Fiscal Year: 2010
    ....
  2. Identifying Genes for Mammographic Breast Density
    Celine M Vachon; Fiscal Year: 2010
    ..At the conclusion of this work, we will have identified at least one gene with a strong genetic influence on breast density and examined the evidence for its role in breast cancer risk. ..
  3. Identifying Genes for Mammographic Breast Density
    Celine Vachon; Fiscal Year: 2009
    ..abstract_text> ..
  4. A Mayo Cohort Study of Mammographic Breast Density
    Celine Vachon; Fiscal Year: 2007
    ..The findings from these proposed studies have obvious translational implications: high-risk groups can be identified for intervention, more aggressive surveillance and perhaps chemoprevention. ..
  5. Identifying Genes for Mammographic Breast Density
    Celine Vachon; Fiscal Year: 2009
    ....