R Houston Thompson

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. ncbi Applications of positron emission tomography imaging, intraoperative ultrasonography, magnetic resonance imaging, and angiography in the evaluation of renal masses
    R Houston Thompson
    Department of Urology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Curr Urol Rep 5:30-4. 2004
  2. ncbi Endoscopic management of upper tract transitional cell carcinoma in patients with normal contralateral kidneys
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    Urology 71:713-7. 2008
  3. ncbi Radical nephrectomy: too radical for small renal masses?
    R Houston Thompson
    Department of Urology, Mayo Clinic, Rochester, MN 55905, USA
    Lancet 368:823-4. 2006
  4. ncbi Is renal sinus fat invasion the same as perinephric fat invasion for pT3a renal cell carcinoma?
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 174:1218-21. 2005
  5. ncbi Complications of contemporary open nephron sparing surgery: a single institution experience
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 174:855-8. 2005
  6. ncbi Comparison of warm ischemia versus no ischemia during partial nephrectomy on a solitary kidney
    R Houston Thompson
    Department of Urology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Eur Urol 58:331-6. 2010
  7. ncbi Should direct ipsilateral adrenal invasion from renal cell carcinoma be classified as pT3a?
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 173:918-21. 2005
  8. ncbi Every minute counts when the renal hilum is clamped during partial nephrectomy
    R Houston Thompson
    Department of Urology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Eur Urol 58:340-5. 2010
  9. ncbi Costimulatory molecule B7-H1 in primary and metastatic clear cell renal cell carcinoma
    R Houston Thompson
    Department of Urology, Mayo Medical School, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 104:2084-91. 2005
  10. ncbi Renal function after partial nephrectomy: effect of warm ischemia relative to quantity and quality of preserved kidney
    R Houston Thompson
    Mayo Medical School and Mayo Clinic, Rochester, Minnesota, USA
    Urology 79:356-60. 2012

Collaborators

Detail Information

Publications69

  1. ncbi Applications of positron emission tomography imaging, intraoperative ultrasonography, magnetic resonance imaging, and angiography in the evaluation of renal masses
    R Houston Thompson
    Department of Urology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Curr Urol Rep 5:30-4. 2004
    ....
  2. ncbi Endoscopic management of upper tract transitional cell carcinoma in patients with normal contralateral kidneys
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    Urology 71:713-7. 2008
    ..We report our experience using ureteroscopic or percutaneous management of upper tract transitional cell carcinoma (TCC) in elective situations...
  3. ncbi Radical nephrectomy: too radical for small renal masses?
    R Houston Thompson
    Department of Urology, Mayo Clinic, Rochester, MN 55905, USA
    Lancet 368:823-4. 2006
  4. ncbi Is renal sinus fat invasion the same as perinephric fat invasion for pT3a renal cell carcinoma?
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 174:1218-21. 2005
    ..We investigated the prognostic significance of each of these pathological features using a cohort of pT3a patients...
  5. ncbi Complications of contemporary open nephron sparing surgery: a single institution experience
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 174:855-8. 2005
    ..We reviewed our experience with contemporary open NSS, comparing complication rates to those of historical controls and updating data for comparison with minimally invasive procedures...
  6. ncbi Comparison of warm ischemia versus no ischemia during partial nephrectomy on a solitary kidney
    R Houston Thompson
    Department of Urology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Eur Urol 58:331-6. 2010
    ..The safe duration of warm ischemia during partial nephrectomy (PN) remains controversial...
  7. ncbi Should direct ipsilateral adrenal invasion from renal cell carcinoma be classified as pT3a?
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 173:918-21. 2005
    ..In the current study we evaluated the association of direct ipsilateral adrenal invasion with outcome to determine if reclassification of these tumors as pT4 would improve the accuracy of the current tumor classification...
  8. ncbi Every minute counts when the renal hilum is clamped during partial nephrectomy
    R Houston Thompson
    Department of Urology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Eur Urol 58:340-5. 2010
    ..The safe duration of warm ischemia during partial nephrectomy remains controversial...
  9. ncbi Costimulatory molecule B7-H1 in primary and metastatic clear cell renal cell carcinoma
    R Houston Thompson
    Department of Urology, Mayo Medical School, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 104:2084-91. 2005
    ..The authors surmised that B7-H1 blockade may augment current immunotherapy, including patients treated for metastases after cytoreductive nephrectomy...
  10. ncbi Renal function after partial nephrectomy: effect of warm ischemia relative to quantity and quality of preserved kidney
    R Houston Thompson
    Mayo Medical School and Mayo Clinic, Rochester, Minnesota, USA
    Urology 79:356-60. 2012
    ..To evaluate the effects of warm ischemia time (WIT) and quantity and quality of kidney preserved on renal functional recovery after partial nephrectomy (PN). The effect of WIT relative to these other parameters has recently been challenged...
  11. ncbi Reclassification of patients with pT3 and pT4 renal cell carcinoma improves prognostic accuracy
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 104:53-60. 2005
    ..61 vs. 0.55, respectively). CONCLUSIONS: Direct adrenal invasion from RCC should be reclassified as pT4. In addition, the proposed reclassification for patients with pT3 RCC improved prognostic accuracy...
  12. ncbi Elective endoscopic management of transitional cell carcinoma first diagnosed in the upper urinary tract
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, MN 55905, USA
    BJU Int 102:1107-10. 2008
    ..To report our experience using ureteroscopic or percutaneous management of upper urinary tract (UUT) transitional cell carcinoma (TCC) in patients with no history of bladder TCC...
  13. ncbi Survivin and b7-h1 are collaborative predictors of survival and represent potential therapeutic targets for patients with renal cell carcinoma
    Amy E Krambeck
    Department of Urology, Mayo Medical School, Mayo Clinic, Rochester, MN 55905, USA
    Clin Cancer Res 13:1749-56. 2007
    ..Herein, we examine the clinical effect of ccRCC combined expression of both survivin and B7-H1...
  14. ncbi Routine adrenalectomy in patients with locally advanced renal cell cancer does not offer oncologic benefit and places a significant portion of patients at risk for an asynchronous metastasis in a solitary adrenal gland
    Christopher J Weight
    Department of Urology, Mayo Clinic, Rochester, MN 55905, USA
    Eur Urol 60:458-64. 2011
    ..The indications for the removal of the ipsilateral adrenal gland in patients with renal cell carcinoma (RCC) and the long-term outcomes have not been well studied...
  15. ncbi Imperative indications for conservative management of upper tract transitional cell carcinoma
    Amy E Krambeck
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 178:792-6; discussion 796-7. 2007
    ..We report our experience with patients with imperative indications for endoscopic treatment for upper tract transitional cell carcinoma...
  16. ncbi Long-term risk of clinical progression after biochemical recurrence following radical prostatectomy: the impact of time from surgery to recurrence
    Stephen A Boorjian
    Department of Urology, Mayo Clinic, Rochester, MN, USA
    Eur Urol 59:893-9. 2011
    ..The natural history of biochemical recurrence (BCR) after radical retropubic prostatectomy (RRP) is variable and does not always translate into systemic progression or prostate cancer (PCa) death...
  17. ncbi Histologic coagulative tumor necrosis as a prognostic indicator of renal cell carcinoma aggressiveness
    Shomik Sengupta
    Department of Urology, Mayo Medical School and Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Cancer 104:511-20. 2005
    ..90; P < 0.001). CONCLUSIONS: Histologic coagulative tumor necrosis is an independent predictor of outcome for clear cell and chromophobe RCC, and it should be routinely reported and used in clinical assessment...
  18. ncbi B7-H4 expression in renal cell carcinoma and tumor vasculature: associations with cancer progression and survival
    Amy E Krambeck
    Department of Urology, Mayo Medical School, Mayo Clinic, Rochester, MN 55905, USA
    Proc Natl Acad Sci U S A 103:10391-6. 2006
    ..Last, we demonstrate that patients with RCC tumors expressing both B7-H4 and B7-H1 are at an even greater risk of death from RCC...
  19. ncbi B7-H1 glycoprotein blockade: a novel strategy to enhance immunotherapy in patients with renal cell carcinoma
    R Houston Thompson
    Department of Urology, Mayo Medical School, Mayo Clinic, Rochester, Minnesota 55905, USA
    Urology 66:10-4. 2005
    ..35-9.15; P = 0.010). Tumor-associated B7-H1 expression is significantly associated with poor prognosis among patients with clear-cell RCC. Manipulation of B7-H1 with therapeutic intent remains a realistic and viable therapeutic option...
  20. ncbi Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up
    R Houston Thompson
    Department of Urology, Mayo Medical School, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Cancer Res 66:3381-5. 2006
    ..RCC patients with tumor B7-H1 are at significant risk of rapid cancer progression and accelerated rates of mortality. B7-H1 may function as a key determinant in RCC, abrogating immune responses directed against this immunogenic tumor...
  21. ncbi Ki-67 and coagulative tumor necrosis are independent predictors of poor outcome for patients with clear cell renal cell carcinoma and not surrogates for each other
    Matthew K Tollefson
    Department of Urology, Mayo Clinic and Mayo Medical School, Rochester, MN 55905, USA
    Cancer 110:783-90. 2007
    ..Thus, the goal was to directly test whether Ki-67 and necrosis convey similar or distinct information for the prognostic assessment of ccRCC...
  22. ncbi Carbonic anhydrase IX is not an independent predictor of outcome for patients with clear cell renal cell carcinoma
    Bradley C Leibovich
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 25:4757-64. 2007
    ..We attempted to validate the prognostic utility of CAIX expression using a large cohort of ccRCC patients with long-term follow-up...
  23. ncbi Mononuclear cell infiltration in clear-cell renal cell carcinoma independently predicts patient survival
    W Scott Webster
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 107:46-53. 2006
    ..61; P = .028). CONCLUSIONS: Mononuclear cell infiltration is associated with death from RCC even after multivariate adjustment. Routine documentation of mononuclear cell infiltration is recommended during the pathologic assessment of RCC...
  24. ncbi The preoperative erythrocyte sedimentation rate is an independent prognostic factor in renal cell carcinoma
    Shomik Sengupta
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 106:304-12. 2006
    ..For patients with clear cell RCC, the ESR provided useful information above and beyond traditional prognostic algorithms, and it may be valuable for preoperative prognostication...
  25. ncbi Comparative effectiveness for survival and renal function of partial and radical nephrectomy for localized renal tumors: a systematic review and meta-analysis
    Simon P Kim
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 188:51-7. 2012
    ..We performed a systematic review and meta-analysis of partial vs radical nephrectomy for localized renal tumors, considering all cause and cancer specific mortality, and severe chronic kidney disease...
  26. ncbi Endoscopic management of upper tract urothelial carcinoma in patients with a history of bladder urothelial carcinoma
    Amy E Krambeck
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 177:1721-6. 2007
    ..We evaluate the role of endoscopic management of upper tract urothelial carcinoma in patients with a history of primary bladder urothelial carcinoma...
  27. ncbi PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma
    R Houston Thompson
    Department of Urology, Mayo Medical School, Mayo Clinic, Rochester, MN 55905, USA
    Clin Cancer Res 13:1757-61. 2007
    ..Levels of immune cells expressing PD-1 (PD-1(+)) in clinical RCC tumors have not been evaluated. Thus, we tested whether immune cell PD-1 expression is observed within aggressive RCC tumors...
  28. ncbi Tumor cell and tumor vasculature expression of B7-H3 predict survival in clear cell renal cell carcinoma
    Paul L Crispen
    Department of Urology, Mayo Clinic, Rochester, Minnesota, USA
    Clin Cancer Res 14:5150-7. 2008
    ..As such, we evaluated the association of B7-H3 expression with clinicopathologic outcomes in patients treated for ccRCC...
  29. ncbi Radical nephrectomy for pT1a renal masses may be associated with decreased overall survival compared with partial nephrectomy
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota, USA
    J Urol 179:468-71; discussion 472-3. 2008
    ..We reviewed our surgical experience with small renal tumors, comparing overall survival in patients treated with radical and partial nephrectomy...
  30. ncbi Assessment of the pathologic inclusion criteria from contemporary adjuvant clinical trials for predicting disease progression after nephrectomy for renal cell carcinoma
    Simon P Kim
    Department of Urology, Mayo Clinic, Rochester, MN, USA
    Cancer 118:4412-20. 2012
    ..The objective of this study was to evaluate the accuracy of the pathologic inclusion criteria from all contemporary adjuvant trials in predicting disease progression (DP) for renal cell carcinoma (RCC)...
  31. ncbi Metastatic potential of a renal mass according to original tumour size at presentation
    Eric C Umbreit
    Department of Urology, Mayo Clinic, Rochester, MN, USA
    BJU Int 109:190-4; discussion 194. 2012
    ..To determine the metastatic potential of renal masses based on original tumour size...
  32. ncbi Second primary malignancies associated with renal cell carcinoma histological subtypes
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Urol 176:900-3; discussion 903-4. 2006
    ..These results may have important implications for patient education and followup evaluation, and they should prompt mechanistic investigations...
  33. ncbi Cancer specific survival for patients with pT3 renal cell carcinoma-can the 2002 primary tumor classification be improved?
    Bradley C Leibovich
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 173:716-9. 2005
    ..We evaluated the association of tumor thrombus level and fat invasion with outcome to determine if further subclassification would improve the prognostic accuracy of the current classification...
  34. ncbi Renal oncocytoma growth rates before intervention
    Anil Nicholas Kurup
    Departments of Radiology Urology Biomedical Statistics and Informatics Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    BJU Int 110:1444-8. 2012
    ..Secondarily, we found considerable similarity in tumour measurements between observers, suggesting that even low growth rates may be reproducibly documented...
  35. ncbi Approach to the small renal mass: to treat or not to treat
    Simon P Kim
    Department of Urology, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA
    Urol Clin North Am 39:171-9, vi. 2012
    ....
  36. ncbi Histological subtype is an independent predictor of outcome for patients with renal cell carcinoma
    Bradley C Leibovich
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 183:1309-15. 2010
    ..We examined the significance of histological subtype on progression to distant metastasis and cancer specific death after nephrectomy...
  37. ncbi Partial versus radical nephrectomy for 4 to 7 cm renal cortical tumors
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55902, USA
    J Urol 182:2601-6. 2009
    ..We evaluated survival in patients with 4 to 7 cm renal tumors in a bi-institutional collaboration...
  38. ncbi Outcomes and clinicopathologic variables associated with late recurrence after nephrectomy for localized renal cell carcinoma
    Simon P Kim
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Urology 78:1101-6. 2011
    ..To characterize the incidence and clinicopathologic factors associated with late recurrence after surgical resection for renal cell carcinoma (RCC) because the recurrence patterns >5 years after nephrectomy have been poorly described...
  39. ncbi Dynamic outcome prediction in patients with clear cell renal cell carcinoma treated with radical nephrectomy: the D-SSIGN score
    R Houston Thompson
    Department of Urology, Health Sciences Research, Mayo Medical School, Mayo Clinic, Rochester, Minnesota, USA
    J Urol 177:477-80. 2007
    ..We created a dynamic outcome prediction model for continual surveillance that accounts for the disease-free interval following surgery...
  40. ncbi Targeting molecular and cellular inhibitory mechanisms for improvement of antitumor memory responses reactivated by tumor cell vaccine
    W Scott Webster
    Department of Urology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    J Immunol 179:2860-9. 2007
    ..These results have implications for developing clinical antitumoral vaccination regimens in the setting in which tumors express elevated levels of B7-H1 in the presence of abundant Treg cells...
  41. ncbi Surgical resection provides excellent outcomes for patients with cystic clear cell renal cell carcinoma
    W Scott Webster
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Urology 70:900-4; discussion 904. 2007
    ..However, long-term outcome data are lacking. We reviewed our experience with RCC and report on pathologic features and patient outcome associated with the cystic variant...
  42. ncbi Is the GPSM scoring algorithm for patients with prostate cancer valid in the contemporary era?
    R Houston Thompson
    Department of Urology and Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Urol 178:459-63; discussion 463. 2007
    ..It was developed from patients who underwent radical retropubic prostatectomy from 1990 to 1993. We investigated the predictive ability of GPSM in the contemporary era...
  43. ncbi Implications of B7-H1 expression in clear cell carcinoma of the kidney for prognostication and therapy
    R Houston Thompson
    Departments of Urology and Immunology, Mayo Medical School, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Clin Cancer Res 13:709s-715s. 2007
    ..In summary, B7-H1 encompasses a potent independent predictor of prognosis for patients with RCC and an extremely promising target to facilitate immunotherapeutic responses during the management of this treatment-refractory tumor...
  44. ncbi The impact of ischemia time during open nephron sparing surgery on solitary kidneys: a multi-institutional study
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota, USA
    J Urol 177:471-6. 2007
    ..The safe duration of ischemia during nephron sparing surgery remains controversial. We performed a multi-institutional study to evaluate the renal effects of vascular clamping in patients with solitary kidneys...
  45. ncbi Long-term outcome after radical prostatectomy for patients with lymph node positive prostate cancer in the prostate specific antigen era
    Stephen A Boorjian
    Department of Urology and Division of Biostatistics, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 178:864-70; discussion 870-1. 2007
    ..We examined the impact of lymph node metastases on the outcome of patients following radical prostatectomy and investigated prognostic factors that affect survival...
  46. ncbi Natural history of biochemical recurrence after radical prostatectomy with adjuvant radiation therapy
    Stephen A Boorjian
    Department of Urology, Mayo Clinic, Rochester, Minnesota Electronic address
    J Urol 188:1761-6. 2012
    ..We evaluated the long-term outcome of patients with biochemical recurrence following radical prostatectomy with adjuvant radiation therapy and determined predictors of systemic progression in these men...
  47. ncbi Complications following 573 percutaneous renal radiofrequency and cryoablation procedures
    Thomas D Atwell
    Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55902, USA
    J Vasc Interv Radiol 23:48-54. 2012
    ..To review complications related to percutaneous renal tumor ablation...
  48. ncbi A multidisciplinary evaluation of inter-reviewer agreement of the nephrometry score and the prediction of long-term outcomes
    Christopher J Weight
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 186:1223-8. 2011
    ..However, the reproducibility of scoring has not been rigorously validated across specialty or level of training, nor has it been evaluated with regard to meaningful clinical outcomes...
  49. ncbi Identification of a soluble form of B7-H1 that retains immunosuppressive activity and is associated with aggressive renal cell carcinoma
    Xavier Frigola
    Department of Immunology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Clin Cancer Res 17:1915-23. 2011
    ..Our objective was to determine whether soluble B7-H1 (sB7-H1) levels in patients with clear cell renal cell carcinoma (ccRCC) are associated with pathologic features and patient outcome...
  50. ncbi Radical retropubic prostatectomy in immunosuppressed transplant recipients
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55902, USA
    J Urol 179:1349-52; discussion 1352-3. 2008
    ..We reviewed our experience with radical retropubic prostatectomy in patients with solid organ transplants...
  51. ncbi Preoperative nomogram predicting 12-year probability of metastatic renal cancer
    Ganesh V Raj
    Department of Urology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    J Urol 179:2146-51; discussion 2151. 2008
    ..We developed a predictive model that could be used in the preoperative setting...
  52. ncbi Prognostic Significance of Measured Depth of Invasion of Urothelial Carcinoma of the Bladder Compared to the 2010 American Joint Committee on Cancer pT2 and pT3 Classifications
    Shabnam Zarei
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota
    J Urol 188:1706-11. 2012
    ..We compared the prognostic ability of the current American Joint Committee on Cancer (AJCC) staging system to direct measurement of the depth of tumor invasion into the muscularis propria and perivesical fat...
  53. ncbi High rate of pathologic upgrading at nephroureterectomy for upper tract urothelial carcinoma
    Jeffrey K Wang
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Urology 79:615-9. 2012
    ..Endoscopic biopsy is an important tool for patients with UTUC because the results can influence the management decisions...
  54. ncbi Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target
    R Houston Thompson
    Department of Urology, Mayo Medical School, Mayo Clinic, Rochester, MN 55905, USA
    Proc Natl Acad Sci U S A 101:17174-9. 2004
    ..In addition, B7-H1 may represent a promising target to facilitate more favorable responses in patients who require immunotherapy for treatment of advanced RCC...
  55. ncbi Metachronous renal tumours after surgical management of oncocytoma
    M Adam Childs
    Department of Urology, Mayo Clinic, Rochester, MN 55905, USA
    BJU Int 108:816-9. 2011
    ..To assess the risk of metachronous renal cell carcinoma (RCC) and benign renal tumours after surgical treatment of primary renal oncocytoma...
  56. ncbi TFE3 rearrangements in adult renal cell carcinoma: clinical and pathologic features with outcome in a large series of consecutively treated patients
    William R Sukov
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 36:663-70. 2012
    ..Our findings confirm that RCCs with TFE3 rearrangement account for only approximately 1% of adult RCCs. The results also suggest that adult RCC with TFE3 rearrangement may be a clinically aggressive tumor...
  57. ncbi ALK alterations in adult renal cell carcinoma: frequency, clinicopathologic features and outcome in a large series of consecutively treated patients
    William R Sukov
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Mod Pathol 25:1516-25. 2012
    ..Additional studies are necessary to determine whether patients RCCs with ALK rearrangement and/or those with an increase in ALK copy number would benefit from ALK inhibitor treatment...
  58. ncbi Clinical and pathological features associated with prognosis in patients with papillary renal cell carcinoma
    William R Sukov
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    J Urol 187:54-9. 2012
    ..We determined the clinical and pathological features associated with death from papillary renal cell carcinoma in 395 surgically treated patients...
  59. ncbi The impact of squamous and glandular differentiation on survival after radical cystectomy for urothelial carcinoma
    Simon P Kim
    Department of Urology, Mayo Clinic, Rochester, Minnesota, USA
    J Urol 188:405-9. 2012
    ..We investigated the clinicopathological outcomes of patients treated with cystectomy for pure urothelial carcinoma vs urothelial carcinoma, and squamous and/or glandular differentiation...
  60. ncbi Contemporary trends in nephrectomy for renal cell carcinoma in the United States: results from a population based cohort
    Simon P Kim
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 186:1779-85. 2011
    ..We describe national trends in partial and radical nephrectomy using a contemporary, population based cohort...
  61. ncbi Renal function outcomes in patients treated with partial nephrectomy versus percutaneous ablation for renal tumors in a solitary kidney
    Christopher R Mitchell
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 186:1786-90. 2011
    ..Currently to our knowledge data are lacking on the impact of thermal ablation on renal function preservation. We examined the impact on renal function of partial nephrectomy vs percutaneous ablation in patients with a solitary kidney...
  62. ncbi Significance of B7-H1 overexpression in kidney cancer
    R Houston Thompson
    Departments of Urology and Immunology, Mayo Medical School, Mayo Clinic, Rochester, MN 55905, USA
    Clin Genitourin Cancer 5:206-11. 2006
    ..Based on the current literature, B7-H1 is an independent predictor of prognosis in RCC and represents a promising target for immune manipulation in this refractory tumor...
  63. ncbi Anti-cytotoxic T lymphocyte antigen-4 (CTLA-4) immunotherapy for the treatment of prostate cancer
    R Houston Thompson
    Department of Urology, Mayo Clinic and Mayo Medical School, Rochester, MN 55905, USA
    Urol Oncol 24:442-7. 2006
    ..We review the preclinical and clinical experience with CTLA-4 blockade as a promising immunotherapeutic approach to treat patients with advanced prostate cancer...
  64. ncbi Radical prostatectomy for octogenarians: how old is too old?
    R Houston Thompson
    Department of Urology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Urology 68:1042-5. 2006
    ..Some of these patients will request radical prostatectomy (RP), although outcome data in this population group are lacking. We report our experience with patients undergoing RP during their ninth decade of age...
  65. ncbi Positive surgical margins at partial nephrectomy: predictors and oncological outcomes
    Ofer Yossepowitch
    Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Urol 179:2158-63. 2008
    ..We combine data from 2 tertiary care intuitions, and report predictors of positive surgical margins and long-term oncological outcomes for patients with positive surgical margins...
  66. ncbi Renal cell carcinoma in young and old patients--is there a difference?
    R Houston Thompson
    Department of Surgery Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    J Urol 180:1262-6; discussion 1266. 2008
    ..We reviewed our experience with young patients with renal cell carcinoma and compared them to their older counterparts...
  67. ncbi At what point does warm ischemia cause permanent renal damage during partial nephrectomy?
    R Houston Thompson
    Eur Urol 52:961-3. 2007
  68. ncbi Re: Location of extrarenal tumor extension does not impact survival of patients with pT3a renal cell carcinoma. V. Margulis, P. Tamboli, S. F. Matin, M. Meisner, D. A. Swanson and C. G. Wood. J Urol 2007; 178: 1878-1882
    R Houston Thompson
    J Urol 180:409; author reply 409-10. 2008
  69. ncbi Serum-soluble B7x is elevated in renal cell carcinoma patients and is associated with advanced stage
    R Houston Thompson
    Department of Surgery, Urology Service, Ludwig Center for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Cancer Res 68:6054-8. 2008
    ..These early results merit further investigation of this serum marker for potential diagnostic and prognostic purposes...