Affiliation: Mayo Clinic
- Microseizures and the spatiotemporal scales of human partial epilepsyMatt Stead
Department of Neurology, Mayo Systems Electrophysiology Laboratory, Mayo Clinic, 200 First Street SW, Rochester, MN 55901, USA
Brain 133:2789-97. 2010..Epileptogenesis may involve the creation of these topographically fractured microdomains and ictogenesis (seizure generation), the dynamics of their interaction and spread...
- Surgery for movement disordersW Hu
Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN, USA
J Neurosurg Sci 55:305-17. 2011....
- Multiscale electrophysiology format: an open-source electrophysiology format using data compression, encryption, and cyclic redundancy checkBenjamin H Brinkmann
The Mayo Systems Electrophysiology Lab, Rochester, MN 55905, USA
Conf Proc IEEE Eng Med Biol Soc 2009:7083-6. 2009..Open-source software to read, write, and process these files are provided...
- Spatiotemporal neuronal correlates of seizure generation in focal epilepsyMark R Bower
Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, U S A
Epilepsia 53:807-16. 2012..e., "unit") activity in patients with epilepsy have a long history, no studies have examined long-term firing rates leading into seizures and the spatial relationship of unit activity with respect to the seizure-onset zone...
- Metadata and annotations for multi-scale electrophysiological dataMark R Bower
Mayo Systems Electrophysiology Lab, Rochester, MN 55905, USA
Conf Proc IEEE Eng Med Biol Soc 2009:2811-4. 2009..An example of a graphical utility for generating and evaluating metadata and annotations for "big data" files is presented...
- On the recording reference contribution to EEG correlation, phase synchrony, and coherenceSanqing Hu
Department of Neurology, Division of Epilepsy and Electroencephalography, Mayo Clinic, Rochester, MN 55905, USA
IEEE Trans Syst Man Cybern B Cybern 40:1294-304. 2010..The experimental results demonstrate the significant impact that the recording reference may have on these bivariate measures...
- Synchrony in normal and focal epileptic brain: the seizure onset zone is functionally disconnectedChristopher P Warren
Mayo Systems Electrophysiology Laboratory, Department of Neurology, Division of Epilepsy and Electroencephalography, Mayo Clinic, Rochester, Minnesota 55905, USA
J Neurophysiol 104:3530-9. 2010..We further speculate that this functional isolation may contribute to spontaneous seizure generation and may represent a clinically useful electrophysiological signature for mapping epileptic brain...
- Swine model for translational research of invasive intracranial monitoringJamie J Van Gompel
Department of Neurological Surgery, Mayo Clinic, Rochester, Minnesota, USA
Epilepsia 52:e49-53. 2011..Therefore, we feel this model provides a valuable, reliable, and novel platform for translational studies of implantable hardware for intracranial monitoring...
- Deep brain stimulation in tourette syndrome: a description of 3 patients with excellent outcomeRodolfo Savica
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Mayo Clin Proc 87:59-62. 2012..At 1-year follow-up, the mean reduction in the total Yale Global Tic Severity Scale score in the 3 patients was 70% (range, 60%-80%).Our study further supports the role of the CM/Pf DBS target in medically intractable TS...
- Automatic identification and removal of scalp reference signal for intracranial EEGs based on independent component analysisSanqing Hu
Department of Neurology, Division of Epilepsy and Electroencephalography, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
IEEE Trans Biomed Eng 54:1560-72. 2007..The proposed methods should have wide application in quantitative EEG studies...
- Underlying neurobiology and clinical correlates of mania status after subthalamic nucleus deep brain stimulation in Parkinson's disease: a review of the literatureAmit Chopra
Department of Psychiatry and Psychology, Mayo Clinic, Rochester MN, USA
J Neuropsychiatry Clin Neurosci 24:102-10. 2012..Such working models would serve to further our understanding of the neurobiological underpinnings of mania and contribute valuable new insight toward development of future DBS mood-stabilization therapies...
- Statistical parametric mapping demonstrates asymmetric uptake with Tc-99m ECD and Tc-99m HMPAO SPECT in normal brainBenjamin H Brinkmann
Mayo Systems Electrophysiology Laboratory, Mayo Clinic, Rochester, Minnesota 55905, USA
J Cereb Blood Flow Metab 32:190-8. 2012..The results have important implications for the use of normal control SPECT images in the evaluation of patients with neurologic disease...
- Large-scale electrophysiology: acquisition, compression, encryption, and storage of big dataBenjamin H Brinkmann
Mayo Systems Electrophysiology Laboratory, 1216 Second Street SW, Rochester, MN, USA
J Neurosci Methods 180:185-92. 2009..Data are stored in a file format that incorporates lossless data compression using range-encoded differences, a 32-bit cyclically redundant checksum to ensure data integrity, and 128-bit encryption for protection of patient information...
- Deep brain stimulation in benign tremulous parkinsonismRodolfo Savica
Department of Neurology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Arch Neurol 68:1033-6. 2011..This disorder has an uncertain pathophysiologic relationship to idiopathic Parkinson disease. Deep brain stimulation (DBS) should be efficacious for this condition, but there is no previously published experience...
- Surgically treated movement disorders associated with heterotopia: report of 2 casesJeffrey P Mullin
Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota 55905, USA
J Neurosurg Pediatr 6:267-72. 2010..To the best of our knowledge, these cases are the first reported instances of heterotopic gray matter associated with movement disorders. Both patients experienced significant improvements following resection of their heterotopias...