G E Smith

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. ncbi request reprint A plateau in pre-Alzheimer memory decline: evidence for compensatory mechanisms?
    G E Smith
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    Neurology 69:133-9. 2007
  2. ncbi request reprint What is the outcome we seek? A commentary on Keith et al. (2002)
    Glenn E Smith
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55901, USA
    Neuropsychology 16:432-3. 2002
  3. pmc Atrophy rates accelerate in amnestic mild cognitive impairment
    C R Jack
    Department of Radiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Neurology 70:1740-52. 2008
  4. pmc Brain atrophy rates predict subsequent clinical conversion in normal elderly and amnestic MCI
    C R Jack
    Department of Diagnostic Radiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Neurology 65:1227-31. 2005
  5. pmc DWI predicts future progression to Alzheimer disease in amnestic mild cognitive impairment
    K Kantarci
    Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
    Neurology 64:902-4. 2005
  6. pmc Rates of hippocampal atrophy correlate with change in clinical status in aging and AD
    C R Jack
    Department of Diagnostic Radiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Neurology 55:484-89. 2000
  7. pmc Prediction of AD with MRI-based hippocampal volume in mild cognitive impairment
    C R Jack
    Department of Diagnostic Radiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Neurology 52:1397-403. 1999
  8. pmc Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiologic phenotype
    K A Josephs
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Neurology 70:1850-7. 2008
  9. pmc Mild cognitive impairment and Alzheimer disease: regional diffusivity of water
    K Kantarci
    Department of Diagnostic Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Radiology 219:101-7. 2001
  10. ncbi request reprint DLB fluctuations: specific features that reliably differentiate DLB from AD and normal aging
    T J Ferman
    Department of Psychiatry and Psychology, Mayo Clinic and Foundation, Jacksonville, FL 32224, USA
    Neurology 62:181-7. 2004

Detail Information

Publications96

  1. ncbi request reprint A plateau in pre-Alzheimer memory decline: evidence for compensatory mechanisms?
    G E Smith
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    Neurology 69:133-9. 2007
    ..To compare logistic and bilogistic models to describe the pattern of cognitive decline in the preclinical phase of Alzheimer disease (AD)...
  2. ncbi request reprint What is the outcome we seek? A commentary on Keith et al. (2002)
    Glenn E Smith
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55901, USA
    Neuropsychology 16:432-3. 2002
    ..Rather, the pertinent question may now be, under what conditions and for which people does CABG have the least neuropsychological impact?..
  3. pmc Atrophy rates accelerate in amnestic mild cognitive impairment
    C R Jack
    Department of Radiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Neurology 70:1740-52. 2008
    ..We included comparisons to subjects with aMCI who did not progress (labeled aMCI-S) and also to cognitively normal elderly subjects (CN)...
  4. pmc Brain atrophy rates predict subsequent clinical conversion in normal elderly and amnestic MCI
    C R Jack
    Department of Diagnostic Radiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Neurology 65:1227-31. 2005
    ....
  5. pmc DWI predicts future progression to Alzheimer disease in amnestic mild cognitive impairment
    K Kantarci
    Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
    Neurology 64:902-4. 2005
    ..002). Magnetic resonance diffusion-weighted imaging may help identify patients with aMCI who will progress to AD as well as or better than structural MRI measures of hippocampal atrophy...
  6. pmc Rates of hippocampal atrophy correlate with change in clinical status in aging and AD
    C R Jack
    Department of Diagnostic Radiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Neurology 55:484-89. 2000
    ..69%, AD 3. 5%. CONCLUSION: Rates of hippocampal atrophy match both baseline cognitive status and the change in cognitive status over time in elderly persons who lie along the cognitive continuum from normal to MCI to AD...
  7. pmc Prediction of AD with MRI-based hippocampal volume in mild cognitive impairment
    C R Jack
    Department of Diagnostic Radiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Neurology 52:1397-403. 1999
    ..CONCLUSION: In older patients with MCI, hippocampal atrophy determined by premorbid MRI-based volume measurements is predictive of subsequent conversion to AD...
  8. pmc Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiologic phenotype
    K A Josephs
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Neurology 70:1850-7. 2008
    ....
  9. pmc Mild cognitive impairment and Alzheimer disease: regional diffusivity of water
    K Kantarci
    Department of Diagnostic Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Radiology 219:101-7. 2001
    ..Elevation in hippocampal ADC may reflect early ultrastructural changes in the progression of Alzheimer disease...
  10. ncbi request reprint DLB fluctuations: specific features that reliably differentiate DLB from AD and normal aging
    T J Ferman
    Department of Psychiatry and Psychology, Mayo Clinic and Foundation, Jacksonville, FL 32224, USA
    Neurology 62:181-7. 2004
    ..To determine whether certain aspects of fluctuations reliably distinguish dementia with Lewy bodies (DLB) from Alzheimer's disease (AD) and normal aging...
  11. pmc 1H MR spectroscopy in common dementias
    K Kantarci
    Department of Diagnostic Radiology, Mayo Clinic 200 First St SW, Rochester, MN 55905, USA
    Neurology 63:1393-8. 2004
    ..To determine the 1H MR spectroscopic (MRS) findings and intergroup differences among common dementias: Alzheimer disease (AD), vascular dementia (VaD), dementia with Lewy bodies (DLB), and frontotemporal lobar degeneration (FTLD)...
  12. ncbi request reprint Diagnostic accuracy of four approaches to interpreting neuropsychological test data
    R J Ivnik
    Psychology Division, Mayo Clinic, Rochester, Minnesota 55905, USA
    Neuropsychology 14:163-77. 2000
    ..0 (i.e., chance) to 34.9. The clinical usefulness of absolute scores and difference scores in data interpretation is supported. Neither profile variability measures nor measures of change over time were diagnostically useful...
  13. pmc Comparison of different MRI brain atrophy rate measures with clinical disease progression in AD
    C R Jack
    Department of Diagnostic Radiology and MR Research Laboratory, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Neurology 62:591-600. 2004
    ....
  14. pmc Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease
    C R Jack
    Department of Diagnostic Radiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Neurology 49:786-94. 1997
    ..99 SD, and moderate AD (CDR 2) -2.22 SD. Age- and gender-adjusted, normalized MRI-based hippocampal volumetric measurements provide a sensitive marker of the MTL neuroanatomic degeneration in AD early in the disease process...
  15. ncbi request reprint Mayo's Older Americans Normative Studies: Visual Form Discrimination and copy trial of the Rey-Osterrieth Complex Figure
    M M Machulda
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    J Clin Exp Neuropsychol 29:377-84. 2007
    ..Limitations and unique features of the MOANS normative data are also discussed...
  16. pmc The anatomic correlate of prosopagnosia in semantic dementia
    K A Josephs
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Neurology 71:1628-33. 2008
    ..To determine the anatomic correlate of prosopagnosia in subjects with semantic dementia...
  17. pmc Diffusion tensor imaging and cognitive function in older adults with no dementia
    K Kantarci
    Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Neurology 77:26-34. 2011
    ..To determine the patterns of diffusivity associated with cognitive domain functions in older adults without dementia...
  18. ncbi request reprint Mayo's older Americans normative studies: category fluency norms
    J A Lucas
    Department of Psychiatry and Psychology, Mayo Foundation, Rochester, MN, USA
    J Clin Exp Neuropsychol 20:194-200. 1998
    ..Limitations and unique features of MOANS normative data are also discussed...
  19. ncbi request reprint Normative data for the Mattis Dementia Rating Scale
    J A Lucas
    Department of Psychiatry and Psychology, Mayo Foundation, Rochester, MN, USA
    J Clin Exp Neuropsychol 20:536-47. 1998
    ..Limitations and unique features of MOANS normative data are also discussed...
  20. ncbi request reprint Confrontation naming does not add incremental diagnostic utility in MCI and Alzheimer's disease
    Julie A Testa
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55901, USA
    J Int Neuropsychol Soc 10:504-12. 2004
    ..Collectively these results suggest that although BNT impairments become more common as AD progresses, they are neither necessary for the diagnosis of AD nor particularly useful in identifying early AD...
  21. ncbi request reprint Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease
    B F Boeve
    Department of Neurology, 6Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Brain 130:2770-88. 2007
    ..Furthermore, longitudinal studies in patients with idiopathic RBD are warranted to characterize the natural history of such patients and prepare for future therapeutic trials...
  22. ncbi request reprint REM sleep behavior disorder and dementia: cognitive differences when compared with AD
    T J Ferman
    Department of Psychiatry and Psychology, Mayo Clinic and Foundation, Rochester, MN, USA
    Neurology 52:951-7. 1999
    ....
  23. ncbi request reprint Testing normal older people three or four times at 1- to 2-year intervals: defining normal variance
    R J Ivnik
    Department of Psychiatry and Psychology, Mayo Foundation, Rochester, Minnesota, USA
    Neuropsychology 13:121-7. 1999
    ....
  24. pmc Comparison of memory fMRI response among normal, MCI, and Alzheimer's patients
    M M Machulda
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    Neurology 61:500-6. 2003
    ..To determine whether an fMRI memory encoding task distinguishes among cognitively normal elderly individuals, patients with mild cognitive impairment (MCI), and patients with early Alzheimer's disease (AD)...
  25. pmc Inclusion of RBD improves the diagnostic classification of dementia with Lewy bodies
    T J Ferman
    Department of Psychiatry and Psychology, Mayo Clinic, Jacksonville, FL 32224, USA
    Neurology 77:875-82. 2011
    ..To determine whether adding REM sleep behavior disorder (RBD) to the dementia with Lewy bodies (DLB) diagnostic criteria improves classification accuracy of autopsy-confirmed DLB...
  26. ncbi request reprint Using word recognition tests to estimate premorbid IQ in early dementia: longitudinal data
    G E Smith
    Psychology Division, Mayo Clinic, Rochester, MN 55905, USA
    J Int Neuropsychol Soc 3:528-33. 1997
    ..To aid in clinical interpretation, a table of the normal frequencies of predicted Mayo Verbal IQ minus contemporaneously obtained Mayo Verbal IQ is provided...
  27. ncbi request reprint Neuropathology of cognitively normal elderly
    D S Knopman
    Department of Neurology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    J Neuropathol Exp Neurol 62:1087-95. 2003
    ..The few subjects with more severe AD pathology can be expected based on incidence rates of AD in the very elderly...
  28. ncbi request reprint Subjective memory complaints, psychological distress, and longitudinal change in objective memory performance
    G E Smith
    Department of Psychiatry and Psychology, Mayo Clinic Rochester, Minnesota 55905, USA
    Psychol Aging 11:272-9. 1996
    ..In an approximate census sample of these older people, minor memory problems were reported to be frequent but not serious...
  29. ncbi request reprint Understanding the diagnostic capabilities of cognitive tests
    R J Ivnik
    Department of Psychiatry and Psychology, Mayo Foundation, Rochester, MN, USA
    Clin Neuropsychol 15:114-24. 2001
    ..Information is also provided that helps clinicians quantify a person's risk for cognitive impairment based on specific cognitive test score(s)...
  30. ncbi request reprint Atypical progressive supranuclear palsy underlying progressive apraxia of speech and nonfluent aphasia
    K A Josephs
    Department of Neurology, Division of Behavioural Neurology, Mayo Clinic, Mayo Foundation, Rochester, MN 55905, USA
    Neurocase 11:283-96. 2005
    ..These cases demonstrate that atypical PSP can present as AOS and PNFA without the classic features of PSP...
  31. pmc The influence of apolipoprotein E genotype on visuospatial attention dissipates after age 80
    Selam Negash
    Department of Neurology, Mayo Clinic, USA
    Neuropsychology 23:81-9. 2009
    ..The dissipation of the APOE effect in old-old individuals at lower risk of AD suggests that visuospatial attention impairments seen as early as midlife in APOE-e4 carriers may be a preclinical marker of AD...
  32. pmc 1H magnetic resonance spectroscopy, cognitive function, and apolipoprotein E genotype in normal aging, mild cognitive impairment and Alzheimer's disease
    Kejal Kantarci
    Department of Diagnostic Radiology, Mayo Clinic, Rochester, Minnesota 55901, USA
    J Int Neuropsychol Soc 8:934-42. 2002
    ..Among 1H-MRS measurements, the NAA/MI ratio maybe the most efficient predictor of memory and cognitive function in patients with MCI and AD...
  33. ncbi request reprint Synucleinopathy pathology and REM sleep behavior disorder plus dementia or parkinsonism
    B F Boeve
    Department of Neurology, Mayo Clinic, Rochester, Minneapolis, MN 55905, USA
    Neurology 61:40-5. 2003
    ..To determine if synucleinopathy pathology is related to REM sleep behavior disorder (RBD) plus dementia or parkinsonism...
  34. ncbi request reprint Argyrophilic grain disease in demented subjects presenting initially with amnestic mild cognitive impairment
    Gregory A Jicha
    Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    J Neuropathol Exp Neurol 65:602-9. 2006
    ..AGD is a common pathologic finding in subjects who have been diagnosed with amnestic MCI...
  35. pmc Comparative diagnostic utility of different MR modalities in mild cognitive impairment and Alzheimer's disease
    Kejal Kantarci
    Department of Diagnostic Radiology, Mayo Clinic, Rochester, Minn, USA
    Dement Geriatr Cogn Disord 14:198-207. 2002
    ..Selection of imaging measures used for clinical assessment or monitoring efficiency of therapeutic intervention should be tailored to the clinical stage of the disease...
  36. pmc Age and apoE associations with complex pathologic features in Alzheimer's disease
    Gregory A Jicha
    Department of Neurology, Mayo Clinic, Rochester, MN, Jacksonville, FL, United States
    J Neurol Sci 273:34-9. 2008
    ....
  37. ncbi request reprint Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: evidence of effect modification by apolipoprotein E (APOE)
    S D Edland
    Division of Clinical Epidemiology, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
    Neurosci Lett 345:21-4. 2003
    ..Confirmation of this finding with a larger sample of cases and controls is warranted...
  38. ncbi request reprint Prospective analysis of risk factors for nursing home placement of dementia patients
    G E Smith
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55901, USA
    Neurology 57:1467-73. 2001
    ..To examine risk factors for nursing home placement in a community-based dementia cohort...
  39. pmc Prominent phenotypic variability associated with mutations in Progranulin
    Brendan J Kelley
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Neurobiol Aging 30:739-51. 2009
    ..Some kindreds with PGRN mutations exhibited lateralized topography of degeneration across all affected individuals...
  40. pmc Patterns of atrophy differ among specific subtypes of mild cognitive impairment
    Jennifer L Whitwell
    Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Arch Neurol 64:1130-8. 2007
    ..It follows, however, that subjects with MCI who have impairment in nonmemory domains may progress to non-AD degenerative dementias...
  41. pmc Hippocampal volumes, proton magnetic resonance spectroscopy metabolites, and cerebrovascular disease in mild cognitive impairment subtypes
    Kejal Kantarci
    Department of Diagnostic Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Arch Neurol 65:1621-8. 2008
    ..Noninvasive imaging surrogates for underlying pathological findings in MCI would be clinically useful for identifying patients who may benefit from disease-specific treatments at the prodromal stage of dementia...
  42. ncbi request reprint Dementia with Lewy bodies may present as dementia and REM sleep behavior disorder without parkinsonism or hallucinations
    Tanis J Ferman
    Department of Psychiatry and Psychology, Mayo Clinic and Foundation, Jacksonville, Florida 32224, USA
    J Int Neuropsychol Soc 8:907-14. 2002
    ..This provides further evidence in support of including RBD as one of the core diagnostic features of DLB...
  43. ncbi request reprint Minimal hepatic encephalopathy
    Charmaine A Stewart
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA
    Nat Clin Pract Gastroenterol Hepatol 4:677-85. 2007
    ..This Review focuses on the pathogenesis and neuropsychological findings (incorporating neuroimaging) of MHE, as well as the effect of MHE on quality of life and survival, and developments in treatment...
  44. ncbi request reprint Implicit learning of sequential regularities and spatial contexts in corticobasal syndrome
    Selam Negash
    Mayo Clinic, Rochester, MN 55905, USA
    Neurocase 13:133-43. 2007
    ..These findings provide the first characterization of implicit learning systems in CBS, and show that the two systems are differentially affected in patients with CBS...
  45. ncbi request reprint Comparison of the short test of mental status and the mini-mental state examination in mild cognitive impairment
    David F Tang-Wai
    Department of Neurology, the Mayo Alzheimer s Disease Research Center, Mayo Clinic, Rochester, Minn 55905, USA
    Arch Neurol 60:1777-81. 2003
    ..The Short Test of Mental Status (STMS) was specifically developed for use in dementia assessment and was intended to be more sensitive to problems of learning and mental agility that may be seen in mild cognitive impairment (MCI)...
  46. ncbi request reprint Telehealth home monitoring of solitary persons with mild dementia
    Glenn E Smith
    Alzheimer s Disease Research Center, Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Alzheimers Dis Other Demen 22:20-6. 2007
    ..This difference was also significant. Quantitative and qualitative outcome data from this project are presented...
  47. ncbi request reprint Reliable change on the Dementia Rating Scale
    Otto Pedraza
    Department of Psychiatry and Psychology, Mayo Clinic, Jacksonville, Florida 32224, USA
    J Int Neuropsychol Soc 13:716-20. 2007
    ..In addition, preliminary cross-validation was performed in a clinical comparison sample of another 22 older adults. The findings are discussed in the context of potential clinical and research applications...
  48. ncbi request reprint Long-term subjective memory function in ventricular fibrillation out-of-hospital cardiac arrest survivors resuscitated by early defibrillation
    T Jared Bunch
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
    Resuscitation 60:189-95. 2004
    ..Therefore this study was designed to determine if long-term memory complaints persist in VF OHCA survivors resuscitated in an early defibrillation program when compared with a healthy control population not experiencing cardiac arrest...
  49. ncbi request reprint Alzheimer's disease patients' cognitive status and course years prior to symptom recognition
    Jane H Cerhan
    Mayo Clinic College of Medicine Rochester, Minnesota, USA
    Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 14:227-35. 2007
    ..A significant interaction (but no group effect) was seen for verbal comprehension...
  50. ncbi request reprint De novo genesis of neuropsychiatric symptoms in mild cognitive impairment (MCI)
    Yonas E Geda
    Department of Psychiatry and Psychology, Mayo Clinic Rochester, MN 55905, USA
    Int Psychogeriatr 16:51-60. 2004
    ..There is inadequate information regarding the neuropsychiatric aspect of Mild Cognitive Impairment (MCI)...
  51. pmc Age, family history, and memory and future risk for cognitive impairment
    Dona E C Locke
    Department of Psychiatry and Psychology, Mayo Clinic, Scottsdale, AR 85259, USA
    J Clin Exp Neuropsychol 31:111-6. 2009
    ..To provide a clinical tool for calculating a patient's future risk for developing cognitive impairment based on age, family history, and Rey Auditory Verbal Learning Test (AVLT) retention...
  52. pmc Prevalence of neuropsychiatric symptoms in mild cognitive impairment and normal cognitive aging: population-based study
    Yonas E Geda
    Department of Psychiatry and Psychology, College of Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Arch Gen Psychiatry 65:1193-8. 2008
    ..Little is known about the population-based prevalence of neuropsychiatric symptoms in mild cognitive impairment (MCI)...
  53. pmc Predicting functional decline in behavioural variant frontotemporal dementia
    Keith A Josephs
    Department of Neurology Behavioural Neurology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Brain 134:432-48. 2011
    ....
  54. doi request reprint Utility of the DRS for predicting problems in day-to-day functioning
    Julie A Fields
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Clin Neuropsychol 24:1167-80. 2010
    ..Functional impairments were noted even at mild levels of cognitive impairment. The DRS is helpful for determining the level of assistance that is likely needed in daily care and planning future care needs...
  55. pmc Robust and expanded norms for the Dementia Rating Scale
    Otto Pedraza
    Department of Psychiatry and Psychology, Mayo Clinic, Jacksonville, FL 32224, USA
    Arch Clin Neuropsychol 25:347-58. 2010
    ..The current study presents a reappraisal of the original MOANS DRS norms, provides robust and expanded norms based on a sample of 894 adults age 55 and over, and critically evaluates the benefits of robust norming...
  56. doi request reprint A randomized controlled trial comparing the memory effects of continuation electroconvulsive therapy versus continuation pharmacotherapy: results from the Consortium for Research in ECT (CORE) study
    Glenn E Smith
    Mayo Clinic, Department of Psychiatry and Psychology W11, 200 First Street, SW, Rochester, MN 55905, USA
    J Clin Psychiatry 71:185-93. 2010
    ..To compare the memory effects of continuation electroconvulsive therapy (C-ECT) versus continuation pharmacologic intervention (C-PHARM) at 12 and 24 weeks after completion of acute electroconvulsive therapy (ECT)...
  57. pmc Alzheimer disease-like phenotype associated with the c.154delA mutation in progranulin
    Brendan J Kelley
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Arch Neurol 67:171-7. 2010
    ..To characterize a kindred with a familial neurodegenerative disorder associated with a mutation in progranulin (PGRN), with emphasis on the unique clinical features in this kindred...
  58. pmc Differential item functioning of the Boston Naming Test in cognitively normal African American and Caucasian older adults
    Otto Pedraza
    Department of Psychiatry and Psychology, Mayo Clinic, Jacksonville, Florida 32224, USA
    J Int Neuropsychol Soc 15:758-68. 2009
    ..These findings afford a finer characterization of the psychometric properties of the BNT and expand our understanding of between-group performance...
  59. pmc Functional magnetic resonance imaging changes in amnestic and nonamnestic mild cognitive impairment during encoding and recognition tasks
    Mary M Machulda
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Int Neuropsychol Soc 15:372-82. 2009
    ..The diminished parietal and frontal activation in naMCI may reflect compromised ability to perform nonmemory (i.e., attention/executive, visuospatial function) components of the task...
  60. doi request reprint A cognitive training program based on principles of brain plasticity: results from the Improvement in Memory with Plasticity-based Adaptive Cognitive Training (IMPACT) study
    Glenn E Smith
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Am Geriatr Soc 57:594-603. 2009
    ..To investigate the efficacy of a novel brain plasticity-based computerized cognitive training program in older adults and to evaluate the effect on untrained measures of memory and attention and participant-reported outcomes...
  61. pmc Focal atrophy in dementia with Lewy bodies on MRI: a distinct pattern from Alzheimer's disease
    Jennifer L Whitwell
    Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
    Brain 130:708-19. 2007
    ..Damage to this network of structures in DLB may affect a number of different neurotransmitter systems which in turn may contribute to a number of the core clinical features of DLB...
  62. ncbi request reprint Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease
    Neill R Graff-Radford
    Department of Neuroscience, Mayo College of Medicine, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224, USA
    Arch Neurol 64:354-62. 2007
    ..To develop preventive therapy for Alzheimer disease (AD), it is essential to develop AD-related biomarkers that identify at-risk individuals in the same way that cholesterol levels identify persons at risk for heart disease...
  63. ncbi request reprint Data management and design issues in an unmasked randomized trial of electroconvulsive therapy for relapse prevention of severe depression: the consortium for research in electroconvulsive therapy trial
    Keith G Rasmussen
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    J ECT 23:244-50. 2007
    ..The purpose of this article is to describe the design characteristics and challenges of the trial and of our method of dealing with the lack of double-blind outcome assessment...
  64. ncbi request reprint Neuropathologic features of amnestic mild cognitive impairment
    Ronald C Petersen
    Alzheimer s Disease Research Center and Department of Neurology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Arch Neurol 63:665-72. 2006
    ..The neuropathologic substrate of amnestic mild cognitive impairment (aMCI) is not known...
  65. ncbi request reprint Depression, apolipoprotein E genotype, and the incidence of mild cognitive impairment: a prospective cohort study
    Yonas E Geda
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, Minn, USA
    Arch Neurol 63:435-40. 2006
    ..It remains unknown whether depression and apolipoprotein E genotype are risk factors for incident mild cognitive impairment (MCI)...
  66. ncbi request reprint A brief report on WAIS-R normative data collection in Mayo's Older African Americans Normative Studies
    John A Lucas
    Department of Psychiatry and Psychology, Mayo Clinic, Jacksonville, FL 32224, USA
    Clin Neuropsychol 19:184-8. 2005
    ..As such, WAIS-R normative estimates are not presented here. Interested readers who wish to obtain a full set of MOAANS WAIS-R norms, however, are invited to contact the authors for these data...
  67. pmc Mild cognitive impairment: ten years later
    Ronald C Petersen
    Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Arch Neurol 66:1447-55. 2009
    ..This review summarizes the progress that has been made while also recognizing the challenges that remain...
  68. ncbi request reprint Mayo's Older African Americans Normative Studies: normative data for commonly used clinical neuropsychological measures
    John A Lucas
    Department of Psychiatry and Psychology, Mayo Clinic, Jacksonville, FL 32224, USA
    Clin Neuropsychol 19:162-83. 2005
    ..In most cases, the use of MOAANS norms should improve diagnostic accuracy in dementia evaluations of African American elders...
  69. ncbi request reprint Mayo's Older African Americans Normative Studies: norms for Boston Naming Test, Controlled Oral Word Association, Category Fluency, Animal Naming, Token Test, WRAT-3 Reading, Trail Making Test, Stroop Test, and Judgment of Line Orientation
    John A Lucas
    Department of Psychiatry and Psychology, Mayo Clinic, Jacksonville, FL 32224, USA
    Clin Neuropsychol 19:243-69. 2005
    ..These data should enhance interpretation of individual test performances and facilitate analysis of neuropsychological profile patterns in older African American patients who present for dementia evaluations...
  70. ncbi request reprint Mayo's Older African American Normative Studies: Auditory Verbal Learning Test norms for African American elders
    Tanis J Ferman
    Department of Psychiatry and Psychology, Mayo Foundation, Jacksonville, FL 32224, USA
    Clin Neuropsychol 19:214-28. 2005
    ....
  71. ncbi request reprint Mayo's Older African Americans Normative Studies: WMS-R norms for African American elders
    John A Lucas
    Department of Psychiatry and Psychology, Mayo Clinic, Jacksonville, FL 32224, USA
    Clin Neuropsychol 19:189-213. 2005
    ..We anticipate that these data will enhance the diagnostic utility and clinical interpretation of WMS-R performance in older African Americans...
  72. ncbi request reprint Effects of ApoE genotype and mild cognitive impairment on implicit learning
    Selam Negash
    Mayo Clinic, Rochester, MN 55905, USA
    Neurobiol Aging 28:885-93. 2007
    ....
  73. pmc Longitudinal 1H MRS changes in mild cognitive impairment and Alzheimer's disease
    Kejal Kantarci
    Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Neurobiol Aging 28:1330-9. 2007
    ..Choline/creatine ratio declined in stable MCI, compared to converter MCI patients and cognitively normal elderly, which may be related to a compensatory mechanism in MCI patients who did not to progress to AD...
  74. ncbi request reprint Neuropsychological differentiation of dementia with Lewy bodies from normal aging and Alzheimer's disease
    Tanis J Ferman
    The Department of Psychiatry and Psychology, Mayo Clinic, Jacksonville, FL 32224, USA
    Clin Neuropsychol 20:623-36. 2006
    ..These finding extend prior research suggesting a cognitive profile that can aid in the clinical diagnosis of DLB. Early attention and visual perceptual disturbance suggests DLB, while early impairment in memory and naming suggests AD...
  75. ncbi request reprint Longitudinal characterization of two siblings with frontotemporal dementia and parkinsonism linked to chromosome 17 associated with the S305N tau mutation
    Bradley F Boeve
    Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, MN 55905, USA
    Brain 128:752-72. 2005
    ..These findings have implications for future drug trial development in FTDP-17 and the sporadic tauopathies...
  76. ncbi request reprint Frontotemporal dementia and parkinsonism associated with the IVS1+1G->A mutation in progranulin: a clinicopathologic study
    Bradley F Boeve
    Department of Neurology, Mayo Clinic Rochester, MN 55905, USA
    Brain 129:3103-14. 2006
    ..These findings suggest that the insR352 PSEN1 is not pathogenic, and the IVS1+1G-->A mutation in PGRN causes FTDP associated with FTLD-U pathology and represents a new class of neurodegenerative disease--the 'hypoprogranulinopathies'...
  77. ncbi request reprint DHEA in elderly women and DHEA or testosterone in elderly men
    K Sreekumaran Nair
    Division of Endocrinology, Mayo Clinic, Rochester, MN 55905, USA
    N Engl J Med 355:1647-59. 2006
    ..Dehydroepiandrosterone (DHEA) and testosterone are widely promoted as antiaging supplements, but the long-term benefits, as compared with potential harm, are unknown...
  78. pmc Validation of the neuropathologic criteria of the third consortium for dementia with Lewy bodies for prospectively diagnosed cases
    Hiroshige Fujishiro
    Department of Pathology and Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA
    J Neuropathol Exp Neurol 67:649-56. 2008
    ....
  79. ncbi request reprint Diagnostic utility of letter fluency, category fluency, and fluency difference scores in Alzheimer's disease
    Jane H Cerhan
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    Clin Neuropsychol 16:35-42. 2002
    ..Likelihood ratio tables are provided for use in calculating the odds of AD for specific category fluency and letter fluency scores generated by individual patients...
  80. ncbi request reprint Assessment and management of behavioral disturbances in nursing home patients with dementia
    B Sutor
    Department of Psychiatry and Psychology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Mayo Clin Proc 76:540-50. 2001
    ....
  81. ncbi request reprint Cognitive measures predict pathologic Alzheimer disease
    Matthew R Powell
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
    Arch Neurol 63:865-8. 2006
    ..Neuropsychologic testing is often used to infer neuropathologic processes, but clinicopathologic correlations for individual cognitive measures are based on a small number of published studies...
  82. pmc Antemortem MRI findings correlate with hippocampal neuropathology in typical aging and dementia
    C R Jack
    Department of Diagnostic Radiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Neurology 58:750-7. 2002
    ....
  83. ncbi request reprint Antemortem diagnosis of frontotemporal lobar degeneration
    David S Knopman
    Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN, USA
    Ann Neurol 57:480-8. 2005
    ..The antemortem consensus diagnosis of FTLD was moderately sensitive and very specific. With experienced clinicians and awareness of the unique manifestations of FTLD, accurate antemortem diagnosis was feasible...
  84. ncbi request reprint Mayo's Older Americans Normative Studies: Age- and IQ-Adjusted Norms for the Wechsler Memory Scale--Revised
    Brett A Steinberg
    Comprehensive Neuropsychological Services, P C, Cheshire, CT 06410, USA
    Clin Neuropsychol 19:378-463. 2005
    ..Dodrill, 19971999). Tables of age- and IQ-adjusted percentile equivalents of Mayo age-adjusted WMS-R index scores and MOANS age-adjusted WMS-R subtest scaled scores are presented for eleven age ranges and seven IQ ranges...
  85. ncbi request reprint Mayo's Older Americans Normative Studies: Age- and IQ-Adjusted Norms for the Boston Naming Test, the MAE Token Test, and the Judgment of Line Orientation Test
    Brett A Steinberg
    Comprehensive Neuropsychological Services, P C, Cheshire, CT 06410, USA
    Clin Neuropsychol 19:280-328. 2005
    ..The article concludes with a discussion of factors that may underlie observed relations among age, intelligence, and neuropsychometric test performances...
  86. ncbi request reprint Mayo's Older African American Normative Studies: norms for the Mattis Dementia Rating Scale
    Laurie M Rilling
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Clin Neuropsychol 19:229-42. 2005
    ..These norms should help improve interpretation of DRS performance in African Americans and allow for greater diagnostic accuracy in patients with early cognitive decline...
  87. ncbi request reprint Mayo's older African American normative studies: confirmatory factor analysis of a core battery
    Otto Pedraza
    Department of Clinical and Health Psychology and McKnight Brain Institute, University of Florida, Gainesville, Florida, USA
    J Int Neuropsychol Soc 11:184-91. 2005
    ....
  88. ncbi request reprint A collaborative study of the emergence and clinical features of the major depressive syndrome of Alzheimer's disease
    George S Zubenko
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Room E1230, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Am J Psychiatry 160:857-66. 2003
    ....
  89. ncbi request reprint Proton MR spectroscopy in mild cognitive impairment and Alzheimer disease: comparison of 1.5 and 3 T
    Kejal Kantarci
    Department of Diagnostic Radiology, Milwaukee, WI, USA
    AJNR Am J Neuroradiol 24:843-9. 2003
    ..5 and 3 T to diagnostically discriminate among cognitively normal elderly subjects, patients with mild cognitive impairment (MCI), and patients with Alzheimer disease (AD)...
  90. ncbi request reprint Discrepancies between self-reported years of education and estimated reading level among elderly community-dwelling African-Americans: Analysis of the MOAANS data
    Sid E O'Bryant
    Department of Neuropsychiatry and Behavioral Science, Texas Tech University Health Science Center, Lubbock, TX 79430, USA
    Arch Clin Neuropsychol 22:327-32. 2007
    ..South), parental education and literacy, and percentage of segregation in schooling. Implications of these results are discussed, as are areas for further inquiry...
  91. ncbi request reprint Mayo's Older Americans Normative Studies: Age- and IQ-Adjusted Norms for the Trail-Making Test, the Stroop Test, and MAE Controlled Oral Word Association Test
    Brett A Steinberg
    Comprehensive Neuropsychological Services, P C, Cheshire, CT 06410, USA
    Clin Neuropsychol 19:329-77. 2005
    ..Dodrill, 1997, 1999). Tables of age- and IQ-adjusted percentile equivalents of MOANS age-adjusted TMT, Stroop, and COWAT scores are presented for eleven age ranges and seven IQ ranges...
  92. ncbi request reprint Cognitive asymmetries associated with apolipoprotein E genotype in patients with Alzheimer's disease
    Michael J Finton
    The Wallace Kettering Neuroscience Institute, Kettering, Ohio, USA
    J Int Neuropsychol Soc 9:751-9. 2003
    ..The epsilon4 allele may thus be associated with a specific neurocognitive phenotype among patients with AD, with the overall pattern of cognitive asymmetry dependent upon epsilon4 dose...
  93. ncbi request reprint Mayo's Older Americans Normative Studies: expanded AVLT Recognition Trial norms for ages 57 to 98
    Milton E Harris
    Santa Rosa, CA 95404, USA
    J Clin Exp Neuropsychol 24:214-20. 2002
    ..Observations are offered concerning clinical implications of AVLT Recognition Trial performance. Gender differences in recognition memory are discussed...
  94. ncbi request reprint Mayo's Older Americans Normative Studies: Age- and IQ-Adjusted Norms for the Auditory Verbal Learning Test and the Visual Spatial Learning Test
    Brett A Steinberg
    Comprehensive Neuropsychological Services, P C, Cheshire, CT 06410, USA
    Clin Neuropsychol 19:464-523. 2005
    ....
  95. pmc Detecting dementia with the mini-mental state examination in highly educated individuals
    Sid E O'Bryant
    Department of Neuropsychiatry and Behavioral Science, Texas Tech University Health Sciences Center, 3601 4th St, STOP 8321, Lubbock, TX 79430, USA
    Arch Neurol 65:963-7. 2008
    ..To evaluate the utility of Mini-Mental State Examination (MMSE) scores in detecting cognitive dysfunction in a sample of highly educated individuals...
  96. pmc Neuropsychological findings in clinically atypical autopsy confirmed corticobasal degeneration and progressive supranuclear palsy
    Wendy A VanVoorst
    Parkinsonism Relat Disord 14:376-8. 2008