Research Topics
Species | Mandeep SinghSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Primary angioplasty should be performed in hospitals without on-site surgeryMandeep Singh
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, 200 SW First Street, Rochester, MN 55905, USA
Catheter Cardiovasc Interv 65:1-7. 2005
Thirty-year trends in outcomes of percutaneous coronary interventions in diabetic patientsMandeep Singh
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA
Mayo Clin Proc 88:22-30. 2013..To characterize in-hospital and long-term outcomes after percutaneous coronary interventions (PCIs) in patients with diabetes mellitus (DM)...
Outcomes of a system-wide protocol for elective and nonelective coronary angioplasty at sites without on-site surgery: the Mayo Clinic experienceMandeep Singh
Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Mayo Clin Proc 84:501-8. 2009..To compare outcomes of percutaneous coronary interventions (PCIs) at 2 community hospitals without on-site surgery (Franciscan Skemp Healthcare and Immanuel St. Joseph's Hospital) with a center with on-site surgery (Saint Marys Hospital)...
A critical appraisal of current models of risk stratification for percutaneous coronary interventionsMandeep Singh
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Am Heart J 149:753-60. 2005
Prediction of complications following nonemergency percutaneous coronary interventionsMandeep Singh
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Am J Cardiol 96:907-12. 2005....
Risk stratification following acute myocardial infarctionMandeep Singh
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic College of Medicine, 200 1st Street South West, Rochester, MN 55905, USA
Med Clin North Am 91:603-16; x. 2007..This article highlights the models used for ST-elevation MI (STEMI) and non-ST elevation MI (NSTEMI) and provides an additional description of models used to assess risks after primary angioplasty (ie, angioplasty performed for STEMI)...
Relation of preprocedural statin therapy to in-hospital procedural complications following percutaneous coronary interventions in patients with hyperlipidemiaMandeep Singh
The Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Am J Cardiol 98:325-30. 2006..In conclusion, hyperlipidemia per se is not associated with lower in-hospital complications after PCI. The benefit is largely limited to patients on statin treatment...
Mortality differences between men and women after percutaneous coronary interventions. A 25-year, single-center experienceMandeep Singh
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
J Am Coll Cardiol 51:2313-20. 2008..Our aim was to examine whether gender-based differences in mortality after percutaneous coronary interventions (PCIs) have changed in the past 25 years...
Comorbid conditions and outcomes after percutaneous coronary interventionM Singh
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
Heart 94:1424-8. 2008..To evaluate whether adding comorbid conditions to a risk model can help predict in-hospital outcome and long-term mortality after percutaneous coronary intervention (PCI)...
Twenty-five-year trends in in-hospital and long-term outcome after percutaneous coronary intervention: a single-institution experienceMandeep Singh
Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Circulation 115:2835-41. 2007..Little is known about the impact of technological and pharmacological advances on long-term outcome after percutaneous coronary intervention in general clinical practice...
Bedside estimation of risk from percutaneous coronary intervention: the new Mayo Clinic risk scoresMandeep Singh
Division of Cardiovascular Diseases, College of Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Mayo Clin Proc 82:701-8. 2007..To derive risk models for percutaneous coronary intervention (PCI) outcomes from clinical and laboratory variables available before the procedure so they can be used for preprocedure risk stratification...
Validation of the Mayo clinic risk score for in-hospital mortality after percutaneous coronary interventions using the national cardiovascular data registryMandeep Singh
Mayo Clinic, Rochester, MN 55905, USA
Circ Cardiovasc Interv 1:36-44. 2008..External validation using an independent data set would support broader applicability of the model...
Trends in the association between age and in-hospital mortality after percutaneous coronary intervention: National Cardiovascular Data Registry experienceMandeep Singh
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minn 55905, USA
Circ Cardiovasc Interv 2:20-6. 2009..We sought to determine the importance of age by assessing the in-hospital mortality of stratified age groups in the National Cardiovascular Data Registry...
Percutaneous coronary intervention at centers with and without on-site surgery: a meta-analysisMandeep Singh
Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
JAMA 306:2487-94. 2011..Percutaneous coronary interventions are performed at centers without onsite surgery, despite current guidelines discouraging this...
Comparison of Mayo Clinic risk score and American College of Cardiology/American Heart Association lesion classification in the prediction of adverse cardiovascular outcome following percutaneous coronary interventionsMandeep Singh
Division of Cardiovascular Diseases and Internal Medicine, Rochester, Minnesota, USA
J Am Coll Cardiol 44:357-61. 2004..We compared American College of Cardiology/American Heart Association (ACC/AHA) lesion classification with the recently proposed Mayo Clinic risk score to predict complications following percutaneous coronary intervention (PCI)...
Development and validation of risk adjustment models for long-term mortality and myocardial infarction following percutaneous coronary interventionsMandeep Singh
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA
Circ Cardiovasc Interv 3:423-30. 2010..Our goal was to derive 1- and 5-year mortality and mortality/myocardial infarction (MI) risk models for PCI outcomes from simple, easily obtainable clinical and laboratory variables...
Validation of Mayo Clinic risk adjustment model for in-hospital complications after percutaneous coronary interventions, using the National Heart, Lung, and Blood Institute dynamic registryMandeep Singh
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota55905, USA
J Am Coll Cardiol 42:1722-8. 2003..We sought to validate the recently proposed Mayo Clinic risk score model for complications after percutaneous coronary interventions (PCI), using an independent data set...
Frailty and its potential relevance to cardiovascular careMandeep Singh
Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Mayo Clin Proc 83:1146-53. 2008..We also elaborate on reasons to consider frailty in older adults with cardiovascular disease and focus on its early identification, on referral to specialists, and on care after serious cardiac events...
Influence of frailty and health status on outcomes in patients with coronary disease undergoing percutaneous revascularizationMandeep Singh
Divisions of Cardiovascular Diseases and Department of Health Sciences Research, Division of Endocrinology, Diabetes, Metabolism, and Nutrition, and the Mayo Clinic and Mid America Heart Institute, Rochester, MN 55905, USA
Circ Cardiovasc Qual Outcomes 4:496-502. 2011..Their inclusion improves the discriminatory ability of the Mayo Clinic risk score derived from the routine cardiovascular risk factors...
Safety and efficacy of drug-eluting stent for ST-segment elevation myocardial infarction in an unselected consecutive cohortPieter J Vlaar
Division of Cardiovascular Disease and Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Catheter Cardiovasc Interv 71:764-9. 2008..The objective of this study is to investigate the clinical outcome of a large cohort of patients with ST-segment elevation myocardial infarction (STEMI) treated with drug-eluting stents (DES) compared to bare metal stents (BMS)...
Incidence and prognostic importance of acute renal failure after percutaneous coronary interventionCharanjit S Rihal
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
Circulation 105:2259-64. 2002..0 mg/dL are at higher risk than nondiabetic patients, whereas all patients with a serum Cr >2.0 are at high risk for ARF. ARF was highly correlated with death during the index hospitalization and after dismissal...
Trends in outcomes after percutaneous coronary intervention for chronic total occlusions: a 25-year experience from the Mayo ClinicAbhiram Prasad
Division of Cardiovascular Diseases, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
J Am Coll Cardiol 49:1611-8. 2007....
Major femoral bleeding complications after percutaneous coronary intervention: incidence, predictors, and impact on long-term survival among 17,901 patients treated at the Mayo Clinic from 1994 to 2005Brendan J Doyle
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
JACC Cardiovasc Interv 1:202-9. 2008....
Clinical and economic outcomes after introduction of drug-eluting stentsCharanjit S Rihal
Division of Cardiovascular Diseases, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Am J Manag Care 16:580-7. 2010..In clinical trials, drug-eluting stents (DES) improve clinical outcomes but are more expensive than bare-metal stents (BMS)...
Comparison of frail patients versus nonfrail patients ≥65 years of age undergoing percutaneous coronary interventionS Michael Gharacholou
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA
Am J Cardiol 109:1569-75. 2012..001 for each health status domain). In conclusion, 1/5 of older patients are frail at the time of PCI and have greater comorbid burden, angiographic disease severity, and poorer health status than nonfrail adults...
Elective percutaneous coronary intervention without on-site cardiac surgery: clinical and economic implicationsKirsten Hall Long
Department of Health Sciences Research, Division of Health Care Policy and Research, Mayo Clinic, Rochester, Minnesota 55905, USA
Med Care 44:406-13. 2006....
Correlates of procedural complications and a simple integer risk score for percutaneous coronary interventionMandeep Singh
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
J Am Coll Cardiol 40:387-93. 2002..782 (standard deviation, 0.018). CONCLUSIONS: Eight variables were combined into a convenient bedside risk scoring system that estimates the risk of complications after PCIs...
Predictive factors for ischemic target vessel revascularization in the Prevention of Restenosis with Tranilast and its Outcomes (PRESTO) trialMandeep Singh
Division of Internal Medicine and Cardiovascular Diseases, Mayo Clinic and Foundation, 200 Second Street SW, Rochester, MN 55905, USA
J Am Coll Cardiol 45:198-203. 2005..CONCLUSIONS: Despite being the largest prospective trial designed to test restenosis, the discriminatory ability of the clinical and angiographic variables to predict TVR is modest...
Eptifibatide vs abciximab as adjunctive therapy during primary percutaneous coronary intervention for acute myocardial infarctionGanesh Raveendran
Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 82:196-202. 2007..To compare outcomes among patients receiving eptifibatide or abciximab during primary percutaneous coronary intervention (PCI) for acute myocardial infarction (MI) with ST elevation or new left bundle branch block...
Emergency coronary artery bypass surgery for percutaneous coronary interventions: changes in the incidence, clinical characteristics, and indications from 1979 to 2003Eric H Yang
Division of Cardiovascular Disease and Internal Medicine, Mayo College of Medicine, Rochester, Minnesota 55905, USA
J Am Coll Cardiol 46:2004-9. 2005..However, the in-hospital mortality rate for those requiring emergency CABG remains high and unchanged...
Percutaneous revascularization for stable coronary artery disease temporal trends and impact of drug-eluting stentsAnthony A Hilliard
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
JACC Cardiovasc Interv 3:172-9. 2010..We sought to determine the characteristics, outcomes, and temporal trends among patients undergoing percutaneous coronary intervention (PCI) for stable coronary artery disease (CAD) from a single-center registry...
Scores for post-myocardial infarction risk stratification in the communityMandeep Singh
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Foundation, Rochester, Minn 55905, USA
Circulation 106:2309-14. 2002..CONCLUSION: In the community, comorbidity and EF convey important prognostic information and should be included in approaches for stratifying risk after MI...
Drug-eluting stents in octogenarians: early and intermediate outcomePieter J Vlaar
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA
Am Heart J 155:680-6. 2008..Large randomized controlled trials have demonstrated that percutaneous coronary intervention with the routine use of drug-eluting stents is safe and effective. However, octogenarians are usually excluded from these trials...
In-hospital and long-term outcomes of multivessel percutaneous coronary revascularization after acute myocardial infarctionLin Y Chen
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA
Am J Cardiol 95:349-54. 2005....
Geographical differences in the rates of angiographic restenosis and ischemia-driven target vessel revascularization after percutaneous coronary interventions: results from the Prevention of Restenosis With Tranilast and its Outcomes (PRESTO) TrialMandeep Singh
Division of Internal Medicine and Cardiovascular Diseases, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
J Am Coll Cardiol 47:34-9. 2006..In the absence of a definitive clinical trial to support this view, how should the prudent, cutting-edge cardiologist proceed?..
Low-risk percutaneous coronary interventions without on-site cardiac surgery: two years' observational experience and follow-upHenry H Ting
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
Am Heart J 145:278-84. 2003..We studied the safety and efficacy of performing low-risk elective and acute infarct percutaneous coronary interventions at a community hospital without cardiac surgical capability...
A total of 1,007 percutaneous coronary interventions without onsite cardiac surgery: acute and long-term outcomesHenry H Ting
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
J Am Coll Cardiol 47:1713-21. 2006....
Effect of peripheral arterial disease in patients undergoing percutaneous coronary intervention with intracoronary stentsMandeep Singh
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 79:1113-8. 2004..On follow-up, the short-term and long-term outcomes of patients with PAD were worse, with higher mortality, MI, and need for repeated target vessel revascularization...
Percutaneous coronary intervention for ST-segment and non-ST-segment elevation myocardial infarction at hospitals with and without on-site cardiac surgical capabilityMandeep Singh
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 79:738-44. 2004..CONCLUSION: This study shows that PCI for acute myocardial infarction can be performed safely and effectively in a community hospital without on-site cardiac surgery...
Rheolytic thrombectomy with Angiojet in thrombus-containing lesionsMandeep Singh
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Catheter Cardiovasc Interv 56:1-7. 2002..It is effective in both native coronary arteries and vein graft interventions. However, the long-term outcome of patients with vein graft intervention was worse...
Percutaneous coronary intervention in native vessels with angiographically visible thrombus temporal trends and impact of drug-eluting stentsManivannan Srinivasan
Division of Cardiovascular Diseases and Department of Internal Medicine, Mayo Clinic College of Medicine and Mayo Foundation, Rochester, Rochester, Minnesota, USA
JACC Cardiovasc Interv 3:937-46. 2010..The aim of our study was to evaluate the temporal trends in outcomes following percutaneous coronary intervention in lesions with angiographically visible thrombus and to assess the impact of drug-eluting stents (DES) on long-term outcomes...
Treatment of saphenous vein bypass grafts with ultrasound thrombolysis: a randomized study (ATLAS)Mandeep Singh
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
Circulation 107:2331-6. 2003..1% of abciximab patients (P=0.014). CONCLUSIONS: Use of therapeutic ultrasound in vein graft lesions in patients with acute coronary syndrome had poor angiographic outcome and increased the incidence of acute ischemic complications...
Significance of periprocedural myonecrosis on outcomes after percutaneous coronary intervention: an analysis of preintervention and postintervention troponin T levels in 5487 patientsAbhiram Prasad
Department of Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minn, USA
Circ Cardiovasc Interv 1:10-9. 2008..The aim of this study was to evaluate the relative impact of preprocedural and postprocedural cardiac troponin T (cTnT) levels on survival rate after PCI...
Mayo Clinic Risk Score for percutaneous coronary intervention predicts in-hospital mortality in patients undergoing coronary artery bypass graft surgeryMandeep Singh
Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Circulation 117:356-62. 2008..Our goal was to seek a preprocedure risk model that can predict in-hospital mortality after either percutaneous coronary intervention or coronary artery bypass graft surgery...
Rationale for on-site cardiac surgery for primary angioplasty: a time for reappraisalMandeep Singh
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
J Am Coll Cardiol 39:1881-9. 2002....
Myocardial perfusion in apical ballooning syndrome correlate of myocardial injuryAhmad Elesber
Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
Am Heart J 152:469.e9-13. 2006..Microvascular dysfunction likely play a pivotal role in the pathogenesis of myocardial stunning in ABS...
Cognitive impairment and outcomes in older adult survivors of acute myocardial infarction: findings from the translational research investigating underlying disparities in acute myocardial infarction patients' health status registryS Michael Gharacholou
Mayo Clinic, Rochester, MN, USA
Am Heart J 162:860-869.e1. 2011..Cognitive impairment without dementia (CIND) and acute myocardial infarction (AMI) are prevalent in older adults; however, the association of CIND with outcomes after AMI is unknown...
Isolated elevation in troponin T after percutaneous coronary intervention is associated with higher long-term mortalityAbhiram Prasad
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
J Am Coll Cardiol 48:1765-70. 2006..The aim of this study was to evaluate whether, in patients with normal post-procedure CK-MB, an isolated elevation in cardiac troponin T (cTnT) predicts long-term survival...
Long-term outcome and its predictors among patients with ST-segment elevation myocardial infarction complicated by shock: insights from the GUSTO-I trialMandeep Singh
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
J Am Coll Cardiol 50:1752-8. 2007..This study sought to assess long-term outcome and determine its predictors among 30-day survivors of cardiogenic shock...
Clinical and angiographic predictors of restenosis after percutaneous coronary intervention: insights from the Prevention of Restenosis With Tranilast and Its Outcomes (PRESTO) trialMandeep Singh
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minn 55905, USA
Circulation 109:2727-31. 2004..63. CONCLUSIONS: The preprocedural clinical and angiographic variables from available studies and from the PRESTO trial have only modest predictive ability for restenosis after PCI...
Telemedicine links between developing and developed nationsMandeep Singh
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Indian Heart J 55:188-92. 2003
Prediction of mortality after primary percutaneous coronary intervention for acute myocardial infarction: the CADILLAC risk scoreAmir Halkin
Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York 10022, USA
J Am Coll Cardiol 45:1397-405. 2005..Of note, measurement of baseline left ventricular function is the single most powerful predictor of survival and should be incorporated into risk score models...
The predicament of offering elective percutaneous coronary intervention at sites without on-site cardiac surgeryMandeep Singh
Am Heart J 152:810-1. 2006
Survival benefit with concomitant clopidogrel and glycoprotein IIb/IIIa inhibitor therapy at ad hoc percutaneous coronary interventionRichard J Gumina
Ohio State University, Columbus, USA
Mayo Clin Proc 83:995-1001. 2008..To study clinical outcomes in patients given glycoprotein (GP) IIb/IIIa inhibitors with concomitant clopidogrel at the time of ad hoc percutaneous coronary interventions (PCI)...
Guidelines, lighthouses, and a toe in the waterDavid R Holmes
Circulation 112:2754-5. 2005
Progesterone and the risk of preterm birth among women with a short cervixEduardo B Fonseca
Harris Birthright Research Centre for Fetal Medicine, King s College Hospital, London, United Kingdom
N Engl J Med 357:462-9. 2007..Asymptomatic women found at midgestation to have a short cervix are at greatly increased risk for spontaneous early preterm delivery, and it is unknown whether progesterone reduces this risk in such women...
