Gary L Schwartz

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. ncbi request reprint Association of ambulatory blood pressure with ischemic brain injury
    Gary L Schwartz
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Hypertension 49:1228-34. 2007
  2. pmc The role of plasma renin activity, age, and race in selecting effective initial drug therapy for hypertension
    Gary L Schwartz
    Division of Nephrology and Hypertension, Department of Internal Medicine, College of Medicine, Mayo Clinic, Rochester, MN, USA
    Am J Hypertens 26:957-64. 2013
  3. ncbi request reprint Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity
    Gary L Schwartz
    Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Clin Chem 51:386-94. 2005
  4. ncbi request reprint Interacting effects of gender and genotype on blood pressure response to hydrochlorothiazide
    Gary L Schwartz
    Division of Hypertension, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Kidney Int 62:1718-23. 2002
  5. ncbi request reprint Screening for primary aldosteronism: implications of an increased plasma aldosterone/renin ratio
    Gary L Schwartz
    Division of Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Clin Chem 48:1919-23. 2002
  6. ncbi request reprint Pharmacogenetics of antihypertensive drug responses
    Gary L Schwartz
    Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Am J Pharmacogenomics 4:151-60. 2004
  7. pmc Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker
    Stephen T Turner
    Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, College of Medicine, Rochester, MN 55905, USA
    Hypertension 59:1204-11. 2012
  8. ncbi request reprint Predictors of blood pressure response to the angiotensin receptor blocker candesartan in essential hypertension
    Vincent J Canzanello
    Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, USA
    Am J Hypertens 21:61-6. 2008
  9. pmc Power to identify a genetic predictor of antihypertensive drug response using different methods to measure blood pressure response
    Stephen T Turner
    Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Transl Med 10:47. 2012
  10. pmc Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide
    Stephen T Turner
    Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Hypertension 62:391-7. 2013

Detail Information

Publications38

  1. ncbi request reprint Association of ambulatory blood pressure with ischemic brain injury
    Gary L Schwartz
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Hypertension 49:1228-34. 2007
    ..009 for each). Higher ambulatory blood pressure levels and a nondipping circadian pattern contribute to greater leukoaraiosis volume after controlling for office blood pressure...
  2. pmc The role of plasma renin activity, age, and race in selecting effective initial drug therapy for hypertension
    Gary L Schwartz
    Division of Nephrology and Hypertension, Department of Internal Medicine, College of Medicine, Mayo Clinic, Rochester, MN, USA
    Am J Hypertens 26:957-64. 2013
    ..6ng/ml/h (suppressed PRA) and a renin-angiotensin system blocker for PRA ≥ 0.6ng/ml/h (nonsuppressed PRA)...
  3. ncbi request reprint Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity
    Gary L Schwartz
    Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Clin Chem 51:386-94. 2005
    ..Uncertainty exists, however, regarding its diagnostic accuracy and the effects of antihypertensive drugs and dietary sodium balance on test characteristics...
  4. ncbi request reprint Interacting effects of gender and genotype on blood pressure response to hydrochlorothiazide
    Gary L Schwartz
    Division of Hypertension, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Kidney Int 62:1718-23. 2002
    ..The insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene is associated with variation in serum ACE activity and may influence BP in a gender-specific manner...
  5. ncbi request reprint Screening for primary aldosteronism: implications of an increased plasma aldosterone/renin ratio
    Gary L Schwartz
    Division of Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Clin Chem 48:1919-23. 2002
    ..We determined the sensitivity, specificity, and predictive value of the ratio to identify combinations of renin and aldosterone compatible with primary aldosteronism...
  6. ncbi request reprint Pharmacogenetics of antihypertensive drug responses
    Gary L Schwartz
    Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Am J Pharmacogenomics 4:151-60. 2004
    ..Such studies will require huge sample sizes and novel statistical methods, but the theoretical and technical framework is in place to make this possible...
  7. pmc Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker
    Stephen T Turner
    Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, College of Medicine, Rochester, MN 55905, USA
    Hypertension 59:1204-11. 2012
    ....
  8. ncbi request reprint Predictors of blood pressure response to the angiotensin receptor blocker candesartan in essential hypertension
    Vincent J Canzanello
    Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, USA
    Am J Hypertens 21:61-6. 2008
    ..Response to antihypertensive drugs varies widely among individuals...
  9. pmc Power to identify a genetic predictor of antihypertensive drug response using different methods to measure blood pressure response
    Stephen T Turner
    Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Transl Med 10:47. 2012
    ....
  10. pmc Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide
    Stephen T Turner
    Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Hypertension 62:391-7. 2013
    ....
  11. ncbi request reprint Patent foramen ovale: innocent or guilty? Evidence from a prospective population-based study
    Irene Meissner
    Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Am Coll Cardiol 47:440-5. 2006
    ..We sought to determine the association between patent foramen ovale (PFO), atrial septal aneurysm (ASA), and stroke prospectively in a unselected population sample...
  12. pmc Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic
    Stephen T Turner
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA
    Hypertension 52:359-65. 2008
    ..These results support the use of genome-wide association analyses to identify novel genes influencing antihypertensive drug responses...
  13. ncbi request reprint Effects of endothelial nitric oxide synthase, alpha-adducin, and other candidate gene polymorphisms on blood pressure response to hydrochlorothiazide
    Stephen T Turner
    Division of Hypertension, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Am J Hypertens 16:834-9. 2003
    ....
  14. pmc Associations of microalbuminuria with brain atrophy and white matter hyperintensities in hypertensive sibships
    David S Knopman
    Division of Behavioral Neurology, Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, United States
    J Neurol Sci 271:53-60. 2008
    ..Because of similarities between brain and kidney microvascular disease, there may be a relationship between measures of renal microvascular disease and brain structural changes in middle aged or elderly individuals...
  15. pmc Plasma renin activity predicts blood pressure responses to beta-blocker and thiazide diuretic as monotherapy and add-on therapy for hypertension
    Stephen T Turner
    Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA
    Am J Hypertens 23:1014-22. 2010
    ..Whether these or other characteristics predict blood pressure responses when the drugs are administered as add-on therapy is uncertain...
  16. ncbi request reprint Atherosclerosis of the aorta: risk factor, risk marker, or innocent bystander? A prospective population-based transesophageal echocardiography study
    Irene Meissner
    Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Am Coll Cardiol 44:1018-24. 2004
    ..The goal of this study was to investigate whether complex aortic atherosclerosis is associated with increased risk of vascular events in a non-selected population...
  17. ncbi request reprint Is aortic dilatation an atherosclerosis-related process? Clinical, laboratory, and transesophageal echocardiographic correlates of thoracic aortic dimensions in the population with implications for thoracic aortic aneurysm formation
    Yoram Agmon
    Division of Cardiovascular Diseases and Internal Medicine, Rochester, Minnesota 55905, USA
    J Am Coll Cardiol 42:1076-83. 2003
    ..The study determined, in a population-based setting, whether dilatation of the thoracic aorta is an atherosclerosis-related process...
  18. ncbi request reprint Lack of agreement between office and ambulatory blood pressure responses to hydrochlorothiazide
    Javier Daniel Finkielman
    Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, USA
    Am J Hypertens 18:398-402. 2005
    ..We studied whether the OBP and 24-h ABPM responses to hydrochlorothiazide differ and, if so, the relevance of these differences...
  19. ncbi request reprint WNK1 kinase polymorphism and blood pressure response to a thiazide diuretic
    Stephen T Turner
    Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, MN, USA
    Hypertension 46:758-65. 2005
    ..Polymorphisms in genes regulating renal sodium transport, in particular WNK1, predict interindividual differences in antihypertensive responses to hydrochlorothiazide...
  20. ncbi request reprint Gene markers and antihypertensive therapy
    Stephen T Turner
    Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Curr Hypertens Rep 7:21-30. 2005
    ..Eventually, knowledge of genetic variants that influence BP responses may allow more individualized tailoring of therapy to optimally reduce BP and target-organ damage...
  21. pmc Risk factor profile for chronic kidney disease is similar to risk factor profile for small artery disease
    Stephen T Turner
    Division of Nephrology and Hypertension, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    J Hypertens 29:1796-801. 2011
    ..We then used logistic regression to evaluate the dependency of each measure of disease on conventional risk factors for arteriosclerosis to assess whether the risk factors' effects were proportional across different measures of disease...
  22. ncbi request reprint Reproducibility of blood pressure response to hydrochlorothiazide
    Javier D Finkielman
    Division of Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA
    J Clin Hypertens (Greenwich) 4:408-12. 2002
    ..These results show that the average systolic and diastolic blood pressure responses to hydrochlorothiazide for a group of subjects are reproducible; however, the responses for individual subjects are unpredictable...
  23. ncbi request reprint Ambulatory blood pressure and coronary artery calcification in middle-aged and younger adults
    Stephen T Turner
    Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Am J Hypertens 15:518-24. 2002
    ....
  24. pmc For estimating creatinine clearance measuring muscle mass gives better results than those based on demographics
    Andrew D Rule
    Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA
    Kidney Int 75:1071-8. 2009
    ..Our study shows that the likelihood of chronic kidney disease in the elderly and in women and the risk of adverse outcomes may be inflated by equations that use patient demographics to estimate creatinine generation...
  25. ncbi request reprint A comparison of serum creatinine-based methods for identifying chronic kidney disease in hypertensive individuals and their siblings
    Andrew D Rule
    Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Hypertens 19:608-14. 2006
    ..This study compared kidney disease as defined by reduced eGFR, elevated serum creatinine, or elevated urinary albumin-to-creatinine ratio (ACR)...
  26. ncbi request reprint Renovascular hypertension: balancing the controversies in diagnosis and treatment
    Vesna D Garovic
    Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Cleve Clin J Med 72:1135-44, 1146-7. 2005
    ..Which noninvasive diagnostic test should be considered, and when is renal angiography called for? Which patients will benefit from conservative medical therapy, and when is PTRA appropriate?..
  27. pmc The treatment of hypertension during pregnancy: when should blood pressure medications be started?
    Dawn C Scantlebury
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA
    Curr Cardiol Rep 15:412. 2013
    ....
  28. pmc Obstructive sleep apnea and aldosterone
    Anna Svatikova
    Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    Sleep 32:1589-92. 2009
    ..We tested the hypothesis that serum levels of aldosterone and plasma renin activity (PRA) are increased by apneic sleep in subjects without cardiovascular disease, compared to healthy control subjects...
  29. pmc Screening for adrenal-endocrine hypertension: overview of accuracy and cost-effectiveness
    Gary L Schwartz
    Division of Nephrology and Hypertension, College of Medicine, Mayo Clinic, West 19, Mayo Building, 200 First Street SW, Rochester, MN 55905, USA
    Endocrinol Metab Clin North Am 40:279-94, vii. 2011
    ..Pheochromocytoma is rare; however, because it is a potentially fatal disease, screening strategies should err on the side of not missing the diagnosis, especially in high-risk clinical settings...
  30. ncbi request reprint Correspondence between the adult treatment panel III criteria for metabolic syndrome and insulin resistance
    Justo Sierra-Johnson
    Division of Nephrology and Hypertension, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Diabetes Care 29:668-72. 2006
    ....
  31. ncbi request reprint Relation of coronary artery disease and cerebrovascular disease with atherosclerosis of the thoracic aorta in the general population
    Yoram Agmon
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Am J Cardiol 89:262-7. 2002
    ..Cerebrovascular disease is weakly associated with aortic atherosclerosis, thereby questioning the overall importance of aortic atherosclerosis in the pathogenesis of cerebrovascular events in the general population...
  32. ncbi request reprint Predictors of antihypertensive response to a standard dose of hydrochlorothiazide for essential hypertension
    Arlene B Chapman
    Renal Division, Department of Medicine, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Kidney Int 61:1047-55. 2002
    ....
  33. ncbi request reprint Linear dynamic features of ambulatory blood pressure in a population-based study
    Sharon L R Kardia
    Department of Epidemiology, University of Michigan, 611 Church Street 246, Ann Arbor, MI 48109 2029, USA
    Blood Press Monit 9:259-67. 2004
    ....
  34. ncbi request reprint A multilocus approach to the antihypertensive pharmacogenetics of hydrochlorothiazide
    Anke Hilse Maitland-van der Zee
    Human Genetics Center, University of Texas Health Science Center, Houston, TX 77030, USA
    Pharmacogenet Genomics 15:287-93. 2005
    ..To assess the influence of variations in multiple candidate genes on inter-individual variation in diastolic blood pressure (DBP) response to hydrochlorothiazide...
  35. ncbi request reprint Demographic, environmental, and genetic predictors of metabolic side effects of hydrochlorothiazide treatment in hypertensive subjects
    Anke Hilse Maitland-van der Zee
    Human Genetics Center, University of Texas Health Science Centre, Houston, TX 77030, USA
    Am J Hypertens 18:1077-83. 2005
    ..The aim of this study was to characterize interindividual variation in glucose and lipid responses to hydrochlorothiazide and to identify demographic, environmental, and genetic predictors associated with this variation...
  36. ncbi request reprint Atherosclerotic Vascular Disease Conference: Writing Group V: medical decision making and therapy
    Mark A Creager
    Circulation 109:2634-42. 2004
  37. ncbi request reprint The new hypertension guidelines from JNC 7: is the devil in the details?
    Stephen C Textor
    Mayo Clin Proc 78:1078-81. 2003
  38. ncbi request reprint Personalized medicine for high blood pressure
    Stephen T Turner
    Hypertension 50:1-5. 2007