Michael Sarr

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. ncbi request reprint 2012 revision of the Atlanta classification of acute pancreatitis
    Michael G Sarr
    Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA
    Pol Arch Med Wewn 123:118-24. 2013
  2. doi request reprint The new revised classification of acute pancreatitis 2012
    Michael G Sarr
    Department of Surgery, Mayo Clinic GU 10 01, 200 First Street Southwest, Rochester, MN 55905, USA
    Surg Clin North Am 93:549-62. 2013
  3. doi request reprint Classification of acute pancreatitis--2012: revision of the Atlanta classification and definitions by international consensus
    Peter A Banks
    Division of Gastroenterology, Hepatology, and Endoscopy, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Gut 62:102-11. 2013
  4. doi request reprint The EMPOWER study: randomized, prospective, double-blind, multicenter trial of vagal blockade to induce weight loss in morbid obesity
    Michael G Sarr
    Mayo Clinic, Rochester, MN, USA
    Obes Surg 22:1771-82. 2012
  5. ncbi request reprint CT scan in complicated appendicitis diagnosis: a very costly option
    M G Sarr
    Mayo Clinic College of Medicine, 200 First Street S W, Rochester, MN 55905, USA
    Dig Liver Dis 36:174. 2004
  6. ncbi request reprint Reoperative bariatric surgery
    Michael G Sarr
    Department of Surgery, Mayo Clinic College of Medicine, 200 First Street SW AL 2 435, Rochester, MN 55905, USA
    Surg Endosc 21:1909-13. 2007
  7. ncbi request reprint Open Roux-en-Y gastric bypass: indications and technique
    Michael G Sarr
    Department of Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Gastrointest Surg 8:390-2. 2004
  8. ncbi request reprint Is a bariatric procedure appropriate in patients with portal hypertension secondary to cirrhosis?
    Michael G Sarr
    Department of Surgery, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Surg Obes Relat Dis 2:405-6, discussion 406-7. 2006
  9. ncbi request reprint The laparoscopic adjustable gastric band: we need to keep an open mind--YET STILL
    Michael G Sarr
    Department of Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Gastrointest Surg 9:42-3. 2005
  10. ncbi request reprint Ethical misconduct in publishing: the editors' perspective
    Michael G Sarr
    Gastroenterology Research Unit AL2 435, Mayo Clinic College of Medicine, 200 First Street S W, Rochester, MN 55905, and Harvard Medical School, Massachusetts General Hospital, Boston, USA
    World J Surg 30:1374-6. 2006

Research Grants

  1. ENTERIC PHYSIOLOGY OF THE TRANSPLANTED GUT
    Michael Sarr; Fiscal Year: 2003
  2. ENTERIC PHYSIOLOGY AND FUNCTION OF THE TRANSPLANTED GUT
    Michael Sarr; Fiscal Year: 1993
  3. ENTERIC PHYSIOLOGY OF THE TRANSPLANTED GUT
    Michael Sarr; Fiscal Year: 2007

Detail Information

Publications91

  1. ncbi request reprint 2012 revision of the Atlanta classification of acute pancreatitis
    Michael G Sarr
    Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA
    Pol Arch Med Wewn 123:118-24. 2013
    ..This classification will help the clinician to predict the outcome of patients with acute pancreatitis and will allow comparison of patients and disease treatment/management across countries and practices...
  2. doi request reprint The new revised classification of acute pancreatitis 2012
    Michael G Sarr
    Department of Surgery, Mayo Clinic GU 10 01, 200 First Street Southwest, Rochester, MN 55905, USA
    Surg Clin North Am 93:549-62. 2013
    ..The accurate and consistent description of acute pancreatitis will help to improve the stratification and reporting of new methods of care of acute pancreatitis across different practices, geographic areas, and countries...
  3. doi request reprint Classification of acute pancreatitis--2012: revision of the Atlanta classification and definitions by international consensus
    Peter A Banks
    Division of Gastroenterology, Hepatology, and Endoscopy, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Gut 62:102-11. 2013
    ..The Atlanta classification of acute pancreatitis enabled standardised reporting of research and aided communication between clinicians. Deficiencies identified and improved understanding of the disease make a revision necessary...
  4. doi request reprint The EMPOWER study: randomized, prospective, double-blind, multicenter trial of vagal blockade to induce weight loss in morbid obesity
    Michael G Sarr
    Mayo Clinic, Rochester, MN, USA
    Obes Surg 22:1771-82. 2012
    ..EMPOWER, a randomized, double-blind, prospective, controlled trial was conducted in USA and Australia...
  5. ncbi request reprint CT scan in complicated appendicitis diagnosis: a very costly option
    M G Sarr
    Mayo Clinic College of Medicine, 200 First Street S W, Rochester, MN 55905, USA
    Dig Liver Dis 36:174. 2004
  6. ncbi request reprint Reoperative bariatric surgery
    Michael G Sarr
    Department of Surgery, Mayo Clinic College of Medicine, 200 First Street SW AL 2 435, Rochester, MN 55905, USA
    Surg Endosc 21:1909-13. 2007
  7. ncbi request reprint Open Roux-en-Y gastric bypass: indications and technique
    Michael G Sarr
    Department of Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Gastrointest Surg 8:390-2. 2004
  8. ncbi request reprint Is a bariatric procedure appropriate in patients with portal hypertension secondary to cirrhosis?
    Michael G Sarr
    Department of Surgery, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Surg Obes Relat Dis 2:405-6, discussion 406-7. 2006
  9. ncbi request reprint The laparoscopic adjustable gastric band: we need to keep an open mind--YET STILL
    Michael G Sarr
    Department of Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Gastrointest Surg 9:42-3. 2005
  10. ncbi request reprint Ethical misconduct in publishing: the editors' perspective
    Michael G Sarr
    Gastroenterology Research Unit AL2 435, Mayo Clinic College of Medicine, 200 First Street S W, Rochester, MN 55905, and Harvard Medical School, Massachusetts General Hospital, Boston, USA
    World J Surg 30:1374-6. 2006
  11. ncbi request reprint Primary cystic neoplasms of the pancreas. Neoplastic disorders of emerging importance-current state-of-the-art and unanswered questions
    Michael G Sarr
    Department of Surgery, Mayo Clinic, Rochester, MN, USA
    J Gastrointest Surg 7:417-28. 2003
  12. doi request reprint Structural and functional changes in left and right ventricles after major weight loss following bariatric surgery for morbid obesity
    Carolina A Garza
    Department of Medicine, Caritas St Elizabeth Medical Center, Boston, Massachusetts, USA
    Am J Cardiol 105:550-6. 2010
    ..Weight loss improved the RV end-diastolic area and might prevent progression to RV dysfunction...
  13. doi request reprint Factors influencing lymph node recovery from the operative specimen after gastrectomy for gastric adenocarcinoma
    Scott J Schoenleber
    Division of Gastroenterologic and General Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Gastrointest Surg 13:1233-7. 2009
    ..Currently, the number of lymph nodes examined is frequently less than requirements for accurate staging. Clinical factors associated with lymph node recovery are understood poorly...
  14. ncbi request reprint Unsatisfactory weight loss after vertical banded gastroplasty: is conversion to Roux-en-Y gastric bypass successful?
    Fernando Cordera
    Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA
    Surgery 136:731-7. 2004
    ..Long-term results with VBG are disappointing. We wondered whether patients who had "adapted" to the VBG anatomy and had regained weight would lose weight after conversion to RYGB...
  15. ncbi request reprint Diagnosis and contemporary management of anastomotic leaks after gastric bypass for obesity
    Rodrigo Gonzalez
    Interdisciplinary Obesity Treatment Group, Department of Surgery, University of South Florida Health Sciences Center, Tampa, FL 33601, USA
    J Am Coll Surg 204:47-55. 2007
    ..The objective of this study was to describe the clinical presentation and outcomes of treatment in patients who develop anastomotic leaks after Roux-en-Y gastric bypass for obesity...
  16. ncbi request reprint Ileal resection enhances jejunal absorptive adaptation for water and electrolytes to extrinsic denervation: implications for segmental small bowel transplantation
    Karen D Libsch
    Gastroenterology Research Unit and Department of Surgery, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    J Pediatr Surg 38:502-7. 2003
    ..Segmental small bowel transplantation (SBT) may be an alternative to whole jejunoileal SBT. The aim of this study was to evaluate adaptability of extrinsically denervated jejunum after ileectomy...
  17. ncbi request reprint Staging strategies for pancreatic adenocarcinoma: what the surgeon really wants to know
    Juan M Sarmiento
    Division of Gastroenterologic and General Surgery, Mayo Clinic, 200 First Street SW AL 2 435, Rochester, MN 55905, USA
    Curr Gastroenterol Rep 5:117-24. 2003
    ..This paper addresses the current controversy in staging methodology for pancreatic and periampullary malignancies and offers an approach to the staging of pancreatic cancer...
  18. pmc Expression and function of intestinal hexose transporters after small intestinal denervation
    Corey W Iqbal
    Department of Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Surgery 146:100-12. 2009
    ..We hypothesize that denervation of the small intestine decreases expression of hexose transporters, which leads to decreased glucose absorption...
  19. doi request reprint Refractory strictures after Roux-en-Y gastric bypass: operative management
    Daniel Cusati
    Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA
    Surg Obes Relat Dis 7:165-9. 2011
    ....
  20. doi request reprint Number of lymph nodes evaluated: prognostic value in pancreatic adenocarcinoma
    Marianne Huebner
    Department of Surgery, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    J Gastrointest Surg 16:920-6. 2012
    ..The impact of the number of lymph node (LN) evaluated pathologically on accurate staging is unknown. Our primary aim was to determine a minimum number of evaluated LN needed to provide accurate staging of pancreatic cancer...
  21. ncbi request reprint Cystic neoplasms of the pancreas; what a clinician should know
    George H Sakorafas
    Department of Surgery, 251 Hellenic Air Force HAF Hospital, Messogion and Katehaki Avenue, 115 25 Athens, Greece, and Department of Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Cancer Treat Rev 31:507-35. 2005
    ..In the absence of invasive disease, prognosis is excellent after appropriate surgery. The presence of invasive malignancy signifies a poor prognosis...
  22. pmc Peripancreatic collections in acute pancreatitis: correlation between computerized tomography and operative findings
    Santhi Swaroop Vege
    Miles and Shirley Fiterman Center for Digestive Diseases, 200 First Street SW, Rochester, MN 55905, USA
    World J Gastroenterol 16:4291-6. 2010
    ..To evaluate the ability of contrast-enhanced computerized tomography (CECT) to characterize the nature of peripancreatic collections...
  23. ncbi request reprint Clinical management after bariatric surgery: value of a multidisciplinary approach
    M Molly McMahon
    Division of Endocrinology, Diabetes, Metabolism, and Nutrition Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 81:S34-45. 2006
    ..We present our multidisciplinary approach to postoperative care that is provided after bariatric surgery and that builds on our presurgical evaluation...
  24. ncbi request reprint Development of a simple model of extrinsic denervation of the small bowel in mouse
    Javairiah Fatima
    Department of Surgery, Gastroenterology Research Unit AL 2 435, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Gastrointest Surg 11:1052-6. 2007
    ..This technique in the mouse accomplishes a complete extrinsic denervation of jejunoileum early postoperatively (1 and 3 months); reinnervation occurs by 6 months. This is an easily learned murine model of orthotopic SBT...
  25. doi request reprint Small bowel obstruction-who needs an operation? A multivariate prediction model
    Martin D Zielinski
    Division of Trauma, Critical Care, and General Surgery, Mary Brigh 2 810, St Mary s Hospital, Mayo Clinic, 1216 Second Street SW, Rochester, MN, 55902, USA
    World J Surg 34:910-9. 2010
    ..Our hypothesis was that free intraperitoneal fluid on computed tomography (CT) is associated with the presence of bowel ischemia and need for exploration...
  26. ncbi request reprint Sexual abuse survivors and psychiatric hospitalization after bariatric surgery
    Matthew M Clark
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN, 55905, USA
    Obes Surg 17:465-9. 2007
    ..Some investigators have postulated that a history of being the victim of childhood sexual abuse may impact outcome of bariatric surgery...
  27. doi request reprint Outcomes of intra-abdominal fungal vs. bacterial infections in severe acute pancreatitis
    Santhi Swaroop Vege
    Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Am J Gastroenterol 104:2065-70. 2009
    ..We aimed to compare the morbidity and mortality of IFI compared with intra-abdominal bacterial infection (IBI) and no intra-abdominal infection (NII) in patients with SAP...
  28. doi request reprint Low mortality and high morbidity in severe acute pancreatitis without organ failure: a case for revising the Atlanta classification to include "moderately severe acute pancreatitis"
    Santhi Swaroop Vege
    Department of Medicine, Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Gastroenterol 104:710-5. 2009
    ..Organ failure (OF) is a main cause of death in severe acute pancreatitis (SAP). Our primary aim was to evaluate the morbidity and mortality of patients admitted with SAP with no OF (NOF), single OF (SOF), and multiple (> or =2) OF (MOF)...
  29. doi request reprint Frequency of extrapancreatic neoplasms in intraductal papillary mucinous neoplasm of the pancreas: implications for management
    Kaye M Reid-Lombardo
    Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA
    Ann Surg 251:64-9. 2010
    ..To estimate the frequency of extrapancreatic neoplasms in patients with IPMN compared with those with ductal pancreatic cancer and a general referral population...
  30. doi request reprint Experience with 208 resections for intraductal papillary mucinous neoplasm of the pancreas
    Thomas Schnelldorfer
    Division of Gastroenterologic and General Surgery, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Arch Surg 143:639-46; discussion 646. 2008
    ..Intraductal papillary mucinous neoplasm (IPMN) is an increasingly recognized disease of the pancreas. We report our experience with pancreatic resection for IPMN...
  31. doi request reprint CT findings of walled-off pancreatic necrosis (WOPN): differentiation from pseudocyst and prediction of outcome after endoscopic therapy
    Naoki Takahashi
    Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN, USA
    Eur Radiol 18:2522-9. 2008
    ..Presence of pancreatic duct dilation was associated with pseudocyst. Using a CT score of 2 or higher as a threshold, CT differentiated WOPN from pseudocyst with an accuracy of 79.5-83.6%. Thus, CT can differentiate WOPN from pseudocysts...
  32. doi request reprint Long-term survival after pancreatoduodenectomy for pancreatic adenocarcinoma: is cure possible?
    Thomas Schnelldorfer
    Division of Gastroenterologic and General Surgery Mayo Clinic, Rochester, MN 55905, USA
    Ann Surg 247:456-62. 2008
    ..To determine long-term survival after pancreatoduodenectomy for pancreatic ductal adenocarcinoma and to identify clinical factors associated with long-term survival...
  33. ncbi request reprint Forgotten pioneers of pancreatic surgery: beyond the favorite few
    Thomas Schnelldorfer
    Division of Gastroenterologic and General Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Ann Surg 247:191-202. 2008
  34. pmc Coordinated, diurnal hexose transporter expression in rat small bowel: implications for small bowel resection
    Scott G Houghton
    Department of Surgery, GI Research Unit, Alfred 2, St Mary s Hospital, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
    Surgery 143:79-93. 2008
    ..We hypothesized that hexose transporter levels and glucose absorption follow a coordinated, site-specific diurnal rhythm in rat duodenum and jejunum, but not in ileum...
  35. pmc Hexose transporter expression and function in mouse small intestine: role of diurnal rhythm
    Javairiah Fatima
    Gastroenterology Research Unit GU 1001, Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Gastrointest Surg 13:634-41. 2009
    ..Expression and function of hexose transporters vary diurnally in rat small intestine; however, this subject remains unexplored in mice...
  36. ncbi request reprint A prospective randomized trial comparing standard pancreatoduodenectomy with pancreatoduodenectomy with extended lymphadenectomy in resectable pancreatic head adenocarcinoma
    Michael B Farnell
    Mayo Clinic, Rochester, Minnesota 55905, USA
    Surgery 138:618-28; discussion 628-30. 2005
    ..To compare operative morbidity, mortality, quality of life, and survival after pancreatoduodenectomy (PD) versus pancreatoduodenectomy with extended lymphadenectomy (PD/ELND) in patients with resectable pancreatic cancer...
  37. ncbi request reprint Regional uptake of meal fatty acids in humans
    Michael D Jensen
    1Division of Endocrinology and Metabolism, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Am J Physiol Endocrinol Metab 285:E1282-8. 2003
    ..Using [3H]triolein, we were able to account for virtually 100% of meal fatty acids 24 h after meal ingestion. These results support the meal fatty acid tracer model as a way to study the metabolic fate of dietary fat...
  38. ncbi request reprint Complications of temporary pancreatic stent insertion for pancreaticojejunal anastomosis during pancreaticoduodenectomy
    Michael J Levy
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Gastrointest Endosc 59:719-24. 2004
    ..Four patients with retained transanastomotic pancreatic stent-induced complications after pancreaticduodenectomy were identified...
  39. ncbi request reprint Intraductal papillary mucinous neoplasm: did it exist prior to 1980?
    Matthew K Tollefson
    Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA
    Pancreas 26:e55-8. 2003
    ..Intraductal papillary mucinous neoplasm (IPMN) of the pancreas was first reported in 1982. It is not clear whether the appearance of this neoplasm is a new epidemic or an old disease previously overlooked...
  40. ncbi request reprint Psychosocial factors and 2-year outcome following bariatric surgery for weight loss
    Matthew M Clark
    Departments of Psychiatry and Psychology, Mayo Clinic Rochester, MN 55905, USA
    Obes Surg 13:739-45. 2003
    ..The purpose of this study was to examine the relationship between preoperative psychosocial factors and eventual weight loss...
  41. ncbi request reprint Anesthesiologists, general surgeons, and tobacco interventions in the perioperative period
    David O Warner
    Department of Anesthesiology, Mayo Clinic, 200 First St S W, Rochester, MN 55905, USA
    Anesth Analg 99:1766-73, table of contents. 2004
    ..Intervention opportunities are not exploited consistently in the surgical population; educational efforts directed at physicians in surgical specialties are indicated...
  42. pmc Canine ileal motor activity after a model of jejunoileal autotransplantation
    Toshiyuki Tanaka
    Gastroenterology Research Unit, Mayo Clinic, Rochester, Minnesota 55905, USA
    Ann Surg 237:192-200. 2003
    ..To determine mechanisms by which extrinsic innervation to the jejunoileum controls ileal motility...
  43. ncbi request reprint Safety and efficacy of bariatric surgery in patients with coronary artery disease
    Francisco Lopez-Jimenez
    Department of Internal Medicine and Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 80:1157-62. 2005
    ..To determine the safety and efficacy of bariatric surgery in obese patients with documented coronary artery disease (CAD)...
  44. ncbi request reprint Study of recurrence after surgical resection of intraductal papillary mucinous neoplasm of the pancreas
    Suresh T Chari
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Gastroenterology 123:1500-7. 2002
    ....
  45. ncbi request reprint Differential adrenergic response to extrinsic denervation in canine longitudinal jejunal and ileal smooth muscle
    Nicholas J Zyromski
    Gastroenterology Research Unit and Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA
    J Gastrointest Surg 6:418-25. 2002
    ....
  46. pmc Effect of bariatric surgery on the metabolic syndrome: a population-based, long-term controlled study
    John A Batsis
    Division of Primary Care Internal Medicine, Mayo Clinic, Rochester, MN, USA
    Mayo Clin Proc 83:897-907. 2008
    ..To assess the effect of weight loss by bariatric surgery on the prevalence of the metabolic syndrome (MetS) and to examine predictors of MetS resolution...
  47. ncbi request reprint Role of extrinsic innervation in jejunal absorptive adaptation to subtotal small bowel resection: a model of segmental small bowel transplantation
    Karen D Libsch
    Gastroenterology Research Unit and Department of Surgery, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Gastrointest Surg 6:240-7. 2002
    ..The extrinsic denervation necessitated by small bowel transplantation does not appear to blunt the net jejunal adaptive response to total ileal resection, but may temporarily alter glutamine absorption...
  48. pmc Ano1 is a selective marker of interstitial cells of Cajal in the human and mouse gastrointestinal tract
    Pedro J Gomez-Pinilla
    Enteric Neuroscience Program, Miles and Shirley Fiterman Center for Digestive Diseases and Department of Physiology and Biomedical Engineering, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Am J Physiol Gastrointest Liver Physiol 296:G1370-81. 2009
    ..Ano1 labels all classes of ICC and represents a highly specific marker for studying the distribution of ICC in mouse and human tissues with an advantage over Kit since it does not label mast cells...
  49. ncbi request reprint Open and laparoscopic Roux-en-Y gastric bypass: our techniques
    Sayeed Ikramuddin
    Department of Surgery, University of Minnesota, 420 Delaware Street S E, Mayo Mail Code 195, Minneapolis, MN 55455, USA
    J Gastrointest Surg 11:217-28. 2007
  50. pmc Role of vagal innervation in diurnal rhythm of intestinal peptide transporter 1 (PEPT1)
    Hisham G Qandeel
    Gastrointestinal Research Unit and Department of Surgery, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA
    J Gastrointest Surg 13:1976-85. 2009
    ..We demonstrated previously diurnal variations in expression and function of duodenal and jejunal but not ileal PEPT1; neural regulation of this pattern is unexplored...
  51. ncbi request reprint The malabsorptive very, very long limb Roux-en-Y gastric bypass for super obesity: results in 257 patients
    Wayne K Nelson
    Division of Gastroenterologic and General Surgery, Mayo Clinic College of Medicine, Rochester, Minn, USA
    Surgery 140:517-22, discussion 522-3. 2006
    ..This modified distal gastric bypass establishes a 100-cm common channel (for digestion and absorption) and a "very, very" long Roux limb of 400 to 500 cm...
  52. pmc Major weight loss prevents long-term left atrial enlargement in patients with morbid and extreme obesity
    Carolina A Garza
    Division of Cardiovascular Diseases, Department of Medicine, 200 First St SW, Rochester 55905, MN, USA
    Eur J Echocardiogr 9:587-93. 2008
    ....
  53. doi request reprint Pancreatoduodenectomy for ductal adenocarcinoma: implications of positive margin on survival
    Javairiah Fatima
    Department of Surgery, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Arch Surg 145:167-72. 2010
    ..To assess the effect of R0 resection margin status and R0 en bloc resection in pancreatoduodenectomy outcomes...
  54. ncbi request reprint Anesthesia for a patient with morbid obesity using dexmedetomidine without narcotics
    Roger E Hofer
    Department of Anesthesiology, Mayo Clinic College of Medicine, 200 First Street S W, Rochester, MN 55905, USA
    Can J Anaesth 52:176-80. 2005
    ..To describe the anesthetic management of a patient with extreme obesity undergoing bariatric surgery whose intraoperative narcotic management was entirely substituted with dexmedetomidine...
  55. ncbi request reprint Is Roux-en-Y gastric bypass safe after previous antireflux surgery? Technical feasibility and postoperative symptom assessment
    Scott G Houghton
    Department of Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Surg Obes Relat Dis 1:475-80. 2005
    ..The aim of our study was to assess the technical considerations, morbidity, and safety of RYGBP after previous antireflux surgery and evaluate postoperative reflux symptoms...
  56. ncbi request reprint Postprandial augmentation of absorption of water and electrolytes in jejunum is neurally modulated: implications for segmental small bowel transplantation
    Abdalla E Zarroug
    Gastroenterology Research Unit, Mayo Clinic College of Medicine and Department of Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Gastrointest Surg 10:586-92. 2006
    ..Postprandial augmentation of absorption of water and electrolytes occurs in the in situ jejunum. Disrupting intrinsic neural continuity or extrinsic denervation (as after intestinal transplantation) abolishes postprandial augmentation...
  57. doi request reprint NAFLD and insulin resistance do not increase the risk of postoperative complications among patients undergoing bariatric surgery--a prospective analysis
    Tarsila Ribeireiro
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA
    Obes Surg 21:310-5. 2011
    ..Insulin resistance and NAFLD have been reported to be associated with postoperative complications following major surgery...
  58. ncbi request reprint Pylorus-preserving pancreaticoduodenectomy with complete preservation of the pyloroduodenal blood supply and innervation
    Jeffrey M Gauvin
    Division of Gastroenterologic and General Surgery, Mayo Clinic, Rochester, MN 55905, USA
    Arch Surg 138:1261-3. 2003
  59. ncbi request reprint Small bowel extrinsic denervation does not alter water and electrolyte absorption from the colon in the fasting or early postprandial state
    Troy M Duininck
    Department of Surgery and Gastroenterology Research Unit, Mayo Clinic and Mayo Foundation, Rochester, MN, USA
    J Gastrointest Surg 7:347-53. 2003
    ..These observations suggest that the neurally intact colon has a minimal role in the diarrhea after SBT...
  60. doi request reprint Predictive and prognostic value of CA 19-9 in resected pancreatic adenocarcinoma
    Joshua G Barton
    Department of Surgery, Division of GI and General Surgery, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA
    J Gastrointest Surg 13:2050-8. 2009
    ..Preoperative serum values of CA 19-9 have been reported to be associated with survival in patients undergoing resection of pancreatic adenocarcinoma...
  61. ncbi request reprint Quality-of-life after total pancreatectomy: is it really that bad on long-term follow-up?
    Brian J Billings
    Department of Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Gastrointest Surg 9:1059-66; discussion 1066-7. 2005
    ..QoL after TP is decreased compared with age- and gender-matched controls but not with diabetes from other causes; however, the changes are not overwhelming. TP should remain a viable option but in selected patients...
  62. ncbi request reprint Errant and unrecognized antiperistaltic Roux limb construction during Roux-en-Y gastric bypass for clinically significant obesity
    Lana G Nelson
    Department of Surgery, University of South Florida Health Sciences Center, Tampa, Florida, USA
    Surg Obes Relat Dis 2:523-7. 2006
    ..Proper isoperistaltic orientation of the Roux limb is important. We report on 5 patients with errant anatomic construction of the Roux limb during Roux-en-Y gastric bypass for clinically significant obesity...
  63. ncbi request reprint Nitrergic mechanisms mediating inhibitory control of longitudinal smooth muscle contraction in mouse small intestine
    Tatsuya Ueno
    Department of Surgery and Gastroenterology Research Unit, Mayo Clinic, Rochester, MN 55905, USA
    J Gastrointest Surg 8:831-41. 2004
    ..Nitrergic mechanisms mediate inhibitory control of murine longitudinal small intestinal muscle. Differences exist in neuroregulatory control between jejunum and ileum that may be related to their known difference in motor patterns...
  64. ncbi request reprint Osteomalacia after Roux-en-Y gastric bypass
    Maria L Collazo-Clavell
    Division of Endocrinology, Metabolism and Nutrition, Mayo Clinic Rochester, Rochester, Minnesota 55905, USA
    Endocr Pract 10:195-8. 2004
    ....
  65. ncbi request reprint The diurnal periodicity of hexose transporter mRNA and protein levels in the rat jejunum: role of vagal innervation
    Scott G Houghton
    Department of Surgery, GI Research Unit, Alfred 2, St Mary s Hospital, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Surgery 139:542-9. 2006
    ..Because vagal innervation mediates the diurnal activity of other proteins in the rat small bowel, we hypothesized that the diurnal variation of mRNA and protein levels of these hexose transport proteins are mediated by vagal innervation...
  66. ncbi request reprint Enteric hyperoxaluria, nephrolithiasis, and oxalate nephropathy: potentially serious and unappreciated complications of Roux-en-Y gastric bypass
    Wayne K Nelson
    Mayo Medical School, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Surg Obes Relat Dis 1:481-5. 2005
    ..Our aim was to determine the frequency of the occurrence and effects of enteric hyperoxaluria after RYGBP...
  67. ncbi request reprint Inhibition by nitric oxide and nonadrenergic, noncholinergic (NANC) nerves is preserved in a canine model of extrinsic denervation: implications for small bowel transplantation
    Nicholas J Zyromski
    Gastroenterology Research Unit and Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA
    Surgery 138:905-12. 2005
    ..The aim of this study was to evaluate the role of nitric oxide and nonadrenergic, noncholinergic (NANC) enteric neural input in the nonimmunologic etiology of the dysmotility seen after SBT...
  68. ncbi request reprint In vivo complete neural isolation of the rat jejunoileum: a simple model to study denervation sequelae of intestinal transplantation
    Scott G Houghton
    Department of Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Surg Res 131:53-7. 2006
    ....
  69. ncbi request reprint Effect of Roux-en-Y gastric bypass in obese patients with Barrett's esophagus: attempts to eliminate duodenogastric reflux
    Scott G Houghton
    Department of Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Surg Obes Relat Dis 4:1-4; discussion 4-5. 2008
    ..Obese patients have a high prevalence of gastroesophageal reflux and might be at an increased risk of developing BE and esophageal adenocarcinoma. The effect of eliminating duodenogastroesophageal reflux on BE is not known...
  70. ncbi request reprint Contractile activity of mouse small intestinal longitudinal smooth muscle
    Tatsuya Ueno
    Department of Surgery and the Gastroenterology Research Unit, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Surg Res 118:136-43. 2004
    ..Interest in genomic modulation experimentally often necessitates use of mouse models...
  71. doi request reprint Investigation of antidepressant medication usage after bariatric surgery
    Julie L Cunningham
    Department of Pharmacy, Mayo Clinic, Rochester, MN, USA
    Obes Surg 22:530-5. 2012
    ..While extensive documentation exists on the impact of weight loss surgery on reductions in cardiac, diabetic, and hypertensive medications, little is known about the impact of bariatric surgery on the use of antidepressant medications...
  72. pmc Cellular changes in diabetic and idiopathic gastroparesis
    Madhusudan Grover
    Mayo Clinic, Rochester, Minnesota, USA
    Gastroenterology 140:1575-85.e8. 2011
    ..Cellular changes associated with diabetic and idiopathic gastroparesis are not well described. The aim of this study was to describe histologic abnormalities in gastroparesis and compare findings in idiopathic versus diabetic gastroparesis...
  73. ncbi request reprint Intraductal papillary mucinous neoplasms of the pancreas: a surgical perspective
    George H Sakorafas
    Department of Surgery, 251 Hellenic Air Force Hospital, Arkadias 19 21, GR 115 26 Athens, Greece
    Surg Oncol 14:155-78. 2005
    ..However, invasive IPMNs behave quite similar to ductal adenocarcinoma of the pancreas when analyzed stage-by-stage, with a slightly better prognosis; however, even after an R0 resection, recurrence is common...
  74. ncbi request reprint To the editor: re: "Intraductal papillary-mucinous tumors arising in Santorini's duct"
    Michael G Sarr
    World J Surg 30:481. 2006
  75. ncbi request reprint Chronic extrinsic denervation of the small bowel: effect on adrenergic and cholinergic contractile mechanisms in canine ileal circular muscle
    Bruno M Balsiger
    Gastroenterology Unit, Inselspital, University of Bern, 3010 Bern, Switzerland
    Surgery 134:783-90. 2003
    ..Small bowel transplantation necessitates chronic extrinsic denervation and is often followed by enteric dysfunction. Our aim was to study canine ileal contractile activity after extrinsic denervation...
  76. ncbi request reprint Patients developed symptomatic gallstones between 3 and 21 months after Roux-en-Y gastric bypass (RYGB), neither prophylactic cholecystectomy nor treatment with ursodeoxycholic acid is necessary after open RYGB
    Michael G Sarr
    Surg Obes Relat Dis 2:233; author reply 233. 2006
  77. ncbi request reprint Belsey Mark IV after Roux-en-Y gastric bypass
    Scott G Houghton
    Ann Thorac Surg 82:1171; author reply 1172. 2006
  78. ncbi request reprint Pancreatic mucinous cystic neoplasm defined by ovarian stroma: demographics, clinical features, and prevalence of cancer
    Raghuram P Reddy
    Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, Minnesota, USA
    Clin Gastroenterol Hepatol 2:1026-31. 2004
    ..Our aims were to determine the demographics, clinical features, and prevalence of invasive cancer in MCN defined by the presence of characteristic ovarian stroma...
  79. ncbi request reprint Natural history of intraductal papillary mucinous neoplasms (IPMN): current evidence and implications for management
    Claudio Bassi
    Department of Surgery and Gastroenterology, G B Rossi BorgoRoma Hospital, University of Verona, 37134 Verona, Italy
    J Gastrointest Surg 12:645-50. 2008
    ..4) After resection of noninvasive IPMNs (branch- and main-duct varieties), recurrence is rare (<8%). (5) After resection of invasive IPMN, recurrence occurs in 50-65% of patients...
  80. doi request reprint The success of laparoscopic bariatric surgery--it has come of age and it is safe
    Michael G Sarr
    Ann Surg 248:16-7. 2008
  81. ncbi request reprint Electrogastrography: the study of gastric myoelectric activity. Possible insights into symptoms after restrictive bariatric surgery
    Robert J Greenstein
    Obes Surg 13:669-70. 2003
  82. ncbi request reprint Re: What to expect in the excluded stomach mucosa after vertical banded Roux-en-Y gastric bypass for morbid obesity
    Michael G Sarr
    J Gastrointest Surg 12:396; author reply 398-9. 2008
  83. ncbi request reprint Neuronal adrenergic and muscular cholinergic contractile hypersensitivity in canine jejunum after extrinsic denervation
    Bruno M Balsiger
    Department of Visceral and Transplantation Surgery, University of Bern, Switzerland
    J Gastrointest Surg 7:572-82. 2003
    ..Extrinsic denervation induces enteric neuronal cholinergic and adrenergic smooth muscle hypersensitivity in canine jejunal circular muscle...
  84. ncbi request reprint Research considerations in obesity surgery
    John G Kral
    American Society for Bariatric Surgery, Gainesville, Florida, USA
    Obes Res 10:63-4. 2002
  85. ncbi request reprint Role of extrinsic innervation in modulating nitrergic transmission in the canine ileocolonic region
    Somchai Leelakusolvong
    Division of Gastroenterology and Hepatology, Gastroenterology Research Unit and Enteric Neurosciences Program, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Physiol Gastrointest Liver Physiol 283:G230-9. 2002
    ..Nonnitrergic extrinsic nerve pathways mediate reflex colonic relaxation during ileal distension. Enteric isolation augments the number of NOS fibers, an effect not modified by extrinsic denervation...
  86. ncbi request reprint Scientific data from clinical trials: investigators' responsibilities and rights
    Hiram C Polk
    Arch Surg 137:639-40. 2002
  87. ncbi request reprint Consensus statement on scientific data from clinical trials and investigators' responsibilities and rights
    Hiram C Polk
    Am J Surg 183:605-6. 2002
  88. ncbi request reprint The frequency of respiratory failure in patients with morbid obesity undergoing gastric bypass
    Eleanor L Blouw
    AANA J 71:45-50. 2003
    ..Skillful anesthetic care allows patients with significant comorbid conditions to benefit from bariatric surgery with reasonable risk in terms of postoperative complications...
  89. ncbi request reprint Scientific data from clinical trials: investigators' responsibilities and rights
    Hiram C Polk
    World J Surg 26:637-8. 2002
  90. ncbi request reprint Scientific data from clinical trials: investigators' responsibilities and rights
    Hiram C Polk
    J Vasc Surg 35:1303-4. 2002
  91. doi request reprint Celiac artery stenosis: an underappreciated and unpleasant surprise in patients undergoing pancreaticoduodenectomy
    George H Sakorafas
    4th Department of Surgery, Athens University, Medical School, Attikon University Hospital, Athens, Greece
    J Am Coll Surg 206:349-56. 2008

Research Grants18

  1. ENTERIC PHYSIOLOGY OF THE TRANSPLANTED GUT
    Michael Sarr; Fiscal Year: 2003
    ..This proposal will define important new neural (and hormonal) mechanisms regulating motor and absorptive function in denervated gut. Selected aspects are pertinent to clinical gut transplantation. ..
  2. ENTERIC PHYSIOLOGY AND FUNCTION OF THE TRANSPLANTED GUT
    Michael Sarr; Fiscal Year: 1993
    ..These experiments are directly relevant and will be clinically-applicable in understanding motor and absorptive aspects of the physiology of enteric function after intestinal transplantation...
  3. ENTERIC PHYSIOLOGY OF THE TRANSPLANTED GUT
    Michael Sarr; Fiscal Year: 2007
    ..This proposal will define important, novel neural mechanisms regulating motor and absorptive function in the denervated gut. Selected aspects have translational value to clinical gut transplantation. ..