Frank M Rusnak

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. ncbi Calcineurin: form and function
    F Rusnak
    Section of Hematology Research and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Physiol Rev 80:1483-521. 2000
  2. ncbi Interaction of bacteriophage lambda protein phosphatase with Mn(II): evidence for the formation of a [Mn(II)]2 cluster
    F Rusnak
    Department of Biochemistry and Molecular Biology, Section of Hematology Research, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Biochemistry 38:6943-52. 1999
  3. ncbi Correlation between isoniazid resistance and superoxide reactivity in mycobacterium tuberculosis KatG
    Reza A Ghiladi
    Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143-2280, USA
    J Am Chem Soc 127:13428-42. 2005

Research Grants

  1. MOLECULAR STUDIES OF THE PROTEIN PHOSPHATASE CALCINEURIN
    Frank Rusnak; Fiscal Year: 1993
  2. MOLECULAR STUDIES OF THE PROTEIN PHOSPHATASE CALCINEURIN
    Frank Rusnak; Fiscal Year: 1999
  3. MOLECULAR STUDIES OF THE PROTEIN PHOSPHATASE CALCINEURIN
    Frank Rusnak; Fiscal Year: 2001

Collaborators

Detail Information

Publications3

  1. ncbi Calcineurin: form and function
    F Rusnak
    Section of Hematology Research and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Physiol Rev 80:1483-521. 2000
    ..This review provides a comprehensive examination of the biological roles of calcineurin and reviews aspects related to its structure and catalytic mechanism...
  2. ncbi Interaction of bacteriophage lambda protein phosphatase with Mn(II): evidence for the formation of a [Mn(II)]2 cluster
    F Rusnak
    Department of Biochemistry and Molecular Biology, Section of Hematology Research, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Biochemistry 38:6943-52. 1999
    ..These results are discussed in the context of divalent metal ion activation of this enzyme and possible roles for Mn2+ activation of other serine/threonine protein phosphatases...
  3. ncbi Correlation between isoniazid resistance and superoxide reactivity in mycobacterium tuberculosis KatG
    Reza A Ghiladi
    Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143-2280, USA
    J Am Chem Soc 127:13428-42. 2005
    ....

Research Grants9

  1. MOLECULAR STUDIES OF THE PROTEIN PHOSPHATASE CALCINEURIN
    Frank Rusnak; Fiscal Year: 1993
    ..These experiments will hopefully provide information about the molecular architecture at the surface of this inhibitory complex which interacts with calcineurin and will provide a blueprint for future immunosuppressant drug design...
  2. MOLECULAR STUDIES OF THE PROTEIN PHOSPHATASE CALCINEURIN
    Frank Rusnak; Fiscal Year: 1999
    ....
  3. MOLECULAR STUDIES OF THE PROTEIN PHOSPHATASE CALCINEURIN
    Frank Rusnak; Fiscal Year: 2001
    ..The possibility that calcineurin phosphatase activity may be regulated by the cellular redox provides a link between oxidative stress and calcium- dependent signal transduction pathways. ..