Affiliation: Mayo Clinic
Romero M, Chen A, Parker M, Boron W. The SLC4 family of bicarbonate (HCO??) transporters. Mol Aspects Med. 2013;34:159-82 pubmed publisher
..SLC4 proteins play important roles many modes of acid-base homeostasis: the carriage of CO2 by erythrocytes, the transport of H(+) or HCO3(-) by several epithelia, as well as the regulation of cell volume and intracellular pH...
Rossano A, Romero M. Optical Quantification of Intracellular pH in Drosophila melanogaster Malpighian Tubule Epithelia with a Fluorescent Genetically-encoded pH Indicator. J Vis Exp. 2017;: pubmed publisher
Landry G, Hirata T, Anderson J, Cabrero P, Gallo C, Dow J, et al
. Sulfate and thiosulfate inhibit oxalate transport via a dPrestin (Slc26a6)-dependent mechanism in an insect model of calcium oxalate nephrolithiasis. Am J Physiol Renal Physiol. 2016;310:F152-9 pubmed publisher
..Overall, our findings predict that thiosulfate or oxalate-mimics may be effective as therapeutic competitive inhibitors of CaOx crystallization. ..