Veronique Roger

..The objectives of this study were to determine the effects of sex and of test verification bias on the diagnostic performance of exercise echocardiography...

..In 2000, the definition of myocardial infarction (MI) changed to rely on troponin rather than creatine kinase (CK) and its MB fraction (CK-MB). The implications of this change on trends in MI incidence and outcome are not defined...

..The use of troponins will increase the detection of MI by a magnitude to be quantified, and the clinical acceptance of the new definition is unknown...

..The epidemic of heart failure has yet to be fully investigated, and data on incidence, survival, and sex-specific temporal trends in community-based populations are limited...

..The change in biomarkers used to diagnose myocardial infarction raises several methodologic, clinical, and public health challenges, which are discussed herein...

..To determine the trends in the prevalence of overweight and obese individuals among patients with myocardial infarction (MI), and to assess the association between weight and outcomes after MI...

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..The combination of standardized methodology and of the longitudinal data via the record linkage system of the Rochester Epidemiology Project will allow reliable measures of CHD trends and help define preventive strategies...

..We sought to examine the utilization of exercise stress testing in relation to age and gender in a population-based setting...

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..Accordingly, it is unclear whether the trend in increased use of PCI versus CABG will continue...

..Few population-based studies have been performed. We aimed to estimate the population attributable risk (PAR) associated with key risk factors for heart failure in the community...

..We examined the associations of neutrophil count with mortality and post-MI heart failure (HF) and their incremental value for risk discrimination in the community...

..Earlier recognition of CHD may be associated with higher levels of recognition and treatment of CHD risk factors that may delay incident AMI. To assess timing of CHD and CHD risk factor diagnoses prior to incident AMI...

..We sought to examine temporal trends in the utilization of coronary revascularization in a geographically defined population...

..To estimate the 10-year absolute risk of cardiovascular (CV) events in newly diagnosed rheumatoid arthritis (RA) patients and the potential contribution of CV risk factors to absolute risk assessment...

..However, adjusting for these secular trends in patient characteristics, mortality after HF admission is improving. These data enhance our understanding of the changing natural history of HF...

..To determine the association between asthma and proinflammatory conditions...

..These trends underscore the importance of this growing public health problem...

..This study was designed to determine the effect of gender on the prognostic value of exercise echocardiography...

..To further the understanding of this patient cohort, we performed a population-based study of post-coronary bypass patients who developed recurrent angina...

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..To understand when women's coronary heart disease (CHD) and CHD risk factors are recognized prior to first myocardial infarction (MI)...

..To compare the clinical presentation, management, and outcome of heart failure in patients with rheumatoid arthritis (RA) compared with non-RA patients...

..We also elaborate on reasons to consider frailty in older adults with cardiovascular disease and focus on its early identification, on referral to specialists, and on care after serious cardiac events...

..To examine possible adverse effects of sulfonylureas on survival among patients with diabetes mellitus (DM) who experience a myocardial infarction (MI)...

..In conclusion, kidney stone formers are at increased risk for MI, and this risk is independent of CKD and other risk factors...

..We sought to assess sex differences in clinical presentation, management and outcome in emergency department (ED) patients with chest pain, and to measure the association between female sex and coronary angiography within 30 days...

..As HF is heterogeneous syndrome categorized according to ejection fraction (EF), the association between EF and causes of death is important, yet elusive...

..Adherence to evidence-based medications after myocardial infarction is associated with improved outcomes. However, long-term data on factors affecting medication adherence after myocardial infarction are lacking...

..We assessed these trends by applying the Framingham Heart Study prediction model to national data...

..Mortality among patients with heart failure is high. Though individual biomarkers have been investigated to determine their value in mortality risk prediction, the role of a multimarker strategy requires further evaluation...

..We examined, in a geographically defined community, the prevalence of COPD in patients with MI, its impact on mortality, and how these associations changed over time...

..To examine the impact of systemic inflammation and serum lipids on cardiovascular disease (CVD) in rheumatoid arthritis (RA)...

..We also examined whether RA disease characteristics are associated with the presence of MetS in RA patients without CVD...

..Coronary artery disease is the leading cause of death after TIA. Reliable estimates of the risk of MI after TIA, however, are lacking...

..BACKGROUND; The exercise capacity of patients with known or suspected coronary artery disease (CAD) is of prognostic importance, as is the extent of exercise-related left ventricular (LV) hypoperfusion or dysfunction...

..To compare the characteristics and survival of participants and nonparticipants in a community-based study of myocardial infarction (MI)...

..To identify patients with heart failure (HF) by using language contained in the electronic medical record (EMR)...

..To determine the relationship between glucocorticoid exposure and cardiovascular (CV) events in patients with rheumatoid arthritis (RA)...

..To determine the temporal trends in prevalence of confirmed diabetes mellitus (DM), time from the date DM criteria were met to myocardial infarction (MI), and impact of DM on survival...

..In conclusion, hyperlipidemia per se is not associated with lower in-hospital complications after PCI. The benefit is largely limited to patients on statin treatment...

..To describe the subtypes of lymphocytes in coronary arteries of two patients with rheumatoid arthritis (RA) and coronary artery disease (CAD)...

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..To determine how well patient-reported cardiovascular disease (CVD) and CVD risk factor information agrees with medical record information...

..Intervening successfully to reduce the burden of sudden out-of-hospital death due to coronary heart disease (OHCD) requires knowledge of where these deaths occur and whether they are observed by bystanders...

..The purpose of this study was to determine the mortality trends among RA patients compared with those in the general population...

..We studied the relationship between longer delays from symptom onset to hospital presentation and the use of any reperfusion therapy, door-to-balloon time, and door-to-drug time...

..75; 95% CI=1.28-2.41), but not with na-MCI (OR=1.17; 95% CI=0.69-2.00). The association of CHD with prevalent na-MCI but not with a-MCI suggests that CHD and na-MCI may have similar underlying etiologies...

..Our aim was to examine whether gender-based differences in mortality after percutaneous coronary interventions (PCIs) have changed in the past 25 years...

..Previous studies have demonstrated the effects of single factors, such as age, sex, and race, with longer delays from symptom onset to hospital presentation in patients with ST-elevation myocardial infarction...

..To determine whether statin use is associated with a decreased risk of developing benign prostatic enlargement (BPE) and lower urinary tract symptoms (LUTS)...

..To investigate the mortality associated with cardiovascular diseases and the effect of estrogen treatment in women who underwent unilateral or bilateral oophorectomy before menopause...

..We evaluated the association of Lp-PLA2 with mortality in subjects with HF and assessed its incremental value for risk discrimination over established risk factors and biomarkers...

..We compared hospitalized congestive heart failure (CHF) incidence and prognosis estimates using hospital discharge diagnoses or central adjudication...

..The purpose of this study was to determine the lifetime burden and risk factors for hospitalization after heart failure (HF) diagnosis in the community...

..Although always considered, surgical treatment is often denied because of high operative mortality. Moreover, the effects of surgery for PMR on long-term outcome, particularly compared with expected outcome after MI, are undefined...

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..To evaluate the association of neighborhood-level income and individual-level education with post-myocardial infarction (MI) mortality in community patients...

..A standardized and clear definition of preventable harm is the first step towards safer and more efficient healthcare delivery system. We aimed to summarize the definitions of preventable harm and its conceptualization in healthcare...

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..This study sought to define the prevalence, severity, and significance of pulmonary hypertension (PH) in heart failure with preserved ejection fraction (HFpEF) in the general community...

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..We will summarize the ischemic stroke rate at various time points during follow-up among adults with chronic heart failure...

..We evaluated the distribution of TNFalpha, its association with baseline characteristics and mortality, and its benefit in assessing risk in community HF patients...

..To assess participation bias in the assembly of a specimen repository for genetic studies and to examine the association of participation with outcome within the Olmsted County myocardial infarction (MI) cohort...

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..This suggests that inflammation is related to the ventricular remodeling processes, independently of LV systolic function...

..To determine the risk of hospitalization and death in relation to preexisting depression and anxiety among patients with cardiovascular disease (CVD)...

..Recent changes in the epidemiology of MI justify exploring this relationship. We evaluated whether MI constitutes a risk factor for osteoporotic fracture and examined secular trends in this association...

..The aims of our study were to assess the occurrence of AF among MI patients, determine whether it has changed over time, and quantify its impact and the impact of its timing on mortality after MI...

..To determine medication use and adherence among community-dwelling patients with heart failure (HF)...

..This is crucial to understand the implications of MI diagnoses as newly defined and changing CHD trends, both aspects critically needed for clinical care as well as for epidemiological studies. ..

..To optimize the training potential of these series of studies and the learning experience of mentees a strong mentoring plan is outlined in details in this revised application. ..

..In doing so, we will gain important insights into the burden of hospitalizations among persons living with HF, which are a major driver of human, societal and heath care costs in HF. This will help define preventive strategies. ..

..It will determine the importance of novel biomarkers to predict the risk of adverse events in clinical practice. ..

..Thus, the completion of these aims will provide important insights into the epidemiology of HF. ..

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..Thus, the completion of these aims will provide important insights into the epidemiology of HF. ..

..In doing so, we will gain important insights into the burden of hospitalizations among persons living with HF, which are a major driver of human, societal and heath care costs in HF. This will help define preventive strategies. ..