Research Topics
| Ann M ReedSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Juvenile dermatomyositis: recognition and treatmentAnn M Reed
Division of Rheumatology, Mayo Clinic, Rochester, Minnesota 55905, USA
Paediatr Drugs 4:315-21. 2002..Many other new biological agents are also being tested in myositis...
Antiphospholipid syndrome with catastrophic bleeding and recurrent ischemic strokes as initial presentation of systemic lupus erythematosusVilmarie Rodriguez
Division of Pediatric Hematology Oncology, Mayo Clinic, Rochester, MN 55905, USA
J Pediatr Hematol Oncol 27:403-7. 2005....
Recent advances in juvenile dermatomyositisAnn M Reed
Mayo Medical School, Department of Internal Medicine, 200 First Street, SW E15, Rochester, MN 55905, USA
Curr Rheumatol Rep 7:94-8. 2005..Specifically, this criterion reflects the upregulation of major histocompatibility complex molecules on muscle tissue during acute inflammation...
Epidemiology of sporadic inclusion body myositis and polymyositis in Olmsted County, MinnesotaFloranne C Wilson
Division of Rheumatology, Mayo Clinic, College of Medicine, Rochester, Minnesota 55905, USA
J Rheumatol 35:445-7. 2008..To determine the incidence and prevalence of sporadic inclusion body myositis (sIBM) and polymyositis (PM) in a population-based study...
Dendritic cells and the immunopathogenesis of idiopathic inflammatory myopathiesConsuelo M López de Padilla
Division of Rheumatology, Departments of Medicine, Pediatrics, and Immunology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Curr Opin Rheumatol 20:669-74. 2008..Here, we will discuss the role of dendritic cells in the induction of adaptive immune response in IIM and review the recent literature addressing the role of dendritic cells in the cause and pathogenesis of inflammatory myopathies...
Atypical presentation of Henoch-Schönlein purpuraMark S Mannenbach
Department of Pediatric and Adolescent Medicine and daggerDivision of Pediatric Surgery, Mayo College of Medicine, MN, USA
Pediatr Emerg Care 25:513-5. 2009..Many other organ systems beyond the skin can be involved for children with HSP. We report a case of a 7-year-old girl with HSP who presented with status epilepticus and onset of rash 2 weeks after her initial symptoms...
Does HLA-dependent chimerism underlie the pathogenesis of juvenile dermatomyositis?Ann M Reed
Division of Rheumatology, Department of Medicine, Mayo Clinic and Medical School, Rochester, MN 55905, USA
J Immunol 172:5041-6. 2004..These combined data indicate that chimeric cells play a direct role in the JDM disease process and that the mother's HLA genotype facilitates the transfer and/or persistence of maternal cells in the fetal circulation...
Microchimerism in children with rheumatic disorders: what does it mean?Ann M Reed
Division of Rheumatology, Mayo Clinic, 200 First Street, SW, E15, Rochester, MN 55905, USA
Curr Rheumatol Rep 5:458-62. 2003....
Chimerism in myositisAnn M Reed
Division of Rheumatology, Mayo Clinic, 200 First Street, SW, E15, Rochester, MN 55905, USA
Curr Rheumatol Rep 5:421-4. 2003..Children and adults with inflammatory myositis are reported to have persistence of microchimeric cells more often than healthy individuals in their peripheral blood and muscle tissue...
Steroid-responsive encephalopathy associated with Hashimoto's thyroiditis in an adolescent with chronic hallucinations and depression: case report and reviewFarid H Mahmud
Division of Pediatric Endocrinology and Metabolism, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN 55905, USA
Pediatrics 112:686-90. 2003
Genetic and environmental risk factors for idiopathic inflammatory myopathiesAnn M Reed
Division of Pediatric Rheumatology, Departments of Pediatrics and Internal Medicine, Mayo Clinic Rochester, Mayo Medical School, 200 First Street SW, Rochester, MN 55905, USA
Rheum Dis Clin North Am 28:891-916. 2002....
The inflammatory milieu in idiopathic inflammatory myositisAnn M Reed
Division of Rheumatology, Departments of Pediatrics and Medicine, Mayo Clinic, Rochester, MN 55905, USA
Curr Rheumatol Rep 11:295-301. 2009....
Update in juvenile rheumatoid arthritisThomas G Mason
Mayo Clinic, Rochester, MN 55905, USA
Arthritis Rheum 53:796-9. 2005
Immunopathogenesis of juvenile dermatomyositisSahil Khanna
Division of Rheumatology, Department of Medicine and Pediatrics, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, Minnesota 55905, USA
Muscle Nerve 41:581-92. 2010..These findings also point toward the potential prognostic value of muscle biopsies and have helped expand our understanding of the etiopathogenesis of IIM...
Enzyme elevation in patients with juvenile dermatomyositis and steroid myopathyMaryam Y Naim
Division of Pediatric Rheumatology, Department of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
J Rheumatol 33:1392-4. 2006..We recommend that muscle derived enzyme levels should not be used to differentiate steroid myopathy from inflammatory myopathies...
Extranodal lymphoid microstructures in inflamed muscle and disease severity of new-onset juvenile dermatomyositisConsuelo M López De Padilla
Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Arthritis Rheum 60:1160-72. 2009..We undertook this study to examine the cellular composition, organization, and molecular milieu of the cellular infiltrates in muscle in juvenile DM and to correlate the infiltrates with clinical disease manifestations...
Frequency of abnormal hand and wrist radiographs at time of diagnosis of polyarticular juvenile rheumatoid arthritisTom Mason
Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
J Rheumatol 29:2214-8. 2002..More studies are needed to determine to what extent these radiographic abnormalities correlate with clinical outcomes...
Acute graft-versus-host disease after liver transplantation diagnosed by fluorescent in situ hybridization testing of skin biopsy specimensAlexander Meves
Department of Dermatology, Mayo Clinic, Rochester, Minnesota 55905, USA
J Am Acad Dermatol 55:642-6. 2006..We conclude that early testing of skin biopsy specimens using fluorescent in situ hybridization in sex-mismatched patients with orthotopic liver transplantation can serve as an early diagnostic tool for graft-versus-host disease...
Cushing's syndrome after intra-articular and intradermal administration of triamcinolone acetonide in three pediatric patientsSeema Kumar
Division of Pediatric Endocrinology, Mayo Clinic, Rochester, Minnesota 55905, USA
Pediatrics 113:1820-4. 2004....
Plasmacytoid dendritic cells in inflamed muscle of patients with juvenile dermatomyositisConsuelo M López De Padilla
Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Arthritis Rheum 56:1658-68. 2007..To examine whether dendritic cells (DCs) are constituents of muscle inflammation in juvenile dermatomyositis (DM)...
Rituximab for successful management of probable pediatric catastrophic antiphospholipid syndromeAmulya A Nageswara Rao
Division of Pediatric Hematology and Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA
Pediatr Blood Cancer 52:536-8. 2009..We describe the use of rituximab in the successful initial management of a probable case of pediatric CAPS...
Juvenile dermatomyositis and other idiopathic inflammatory myopathies of childhoodBrian M Feldman
Departments of Pediatrics, Health Policy Management and Evaluation, and Public Health Sciences, University of Toronto, Division of Rheumatology, Hospital for Sick Children, Toronto, ON, Canada
Lancet 371:2201-12. 2008..Disease outcome, if treatment is initiated early, is generally good. Randomised controlled trials are needed to define the most effective treatments...
Immunogenetic risk and protective factors for juvenile dermatomyositis in CaucasiansGulnara Mamyrova
National Institute of Environmental Health Sciences, NIH, Bethesda, Maryland 20892, USA
Arthritis Rheum 54:3979-87. 2006....
Validation and clinical significance of the Childhood Myositis Assessment Scale for assessment of muscle function in the juvenile idiopathic inflammatory myopathiesAdam M Huber
IWK Health Centre and Dalhousie University, 5850 University Avenue, Halifax, Nova Scotia B3J 3G9, Canada
Arthritis Rheum 50:1595-603. 2004....
Alternative scoring of the Cutaneous Assessment Tool in juvenile dermatomyositis: results using abbreviated formatsAdam M Huber
Izaak Walton Killam Health Centre and Dalhousie University, Halifax, Nova Scotia, Canada
Arthritis Rheum 59:352-6. 2008..The goal of this study was to determine whether alternative scoring methods would shorten the CAT without compromising its measurement characteristics...
Preliminary validation and clinical meaning of the Cutaneous Assessment Tool in juvenile dermatomyositisAdam M Huber
Division of Pediatric Rheumatology, IWK Health Centre and Dalhousie University, Halifax, Nova Scotia, Canada
Arthritis Rheum 59:214-21. 2008..To provide preliminary validation of the Cutaneous Assessment Tool (CAT), a new tool to assess cutaneous manifestations of juvenile dermatomyositis (DM), and to explore the clinical meaning of CAT scores...
Normal scores for nine maneuvers of the Childhood Myositis Assessment ScaleRobert M Rennebohm
Division of Pediatric Rheumatolgy, Columbus Children s Hospital and The Ohio State University, 43205, USA
Arthritis Rheum 51:365-70. 2004..To document and evaluate the scores that normal, healthy children achieve when performing 9 maneuvers of the Childhood Myositis Assessment Scale (CMAS)...
Pathogenesis of myositis in childrenThomas A Griffin
William S Rowe Division of Rheumatology, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
Curr Opin Rheumatol 19:487-91. 2007..This review focuses on recent advances in understanding these mechanisms in juvenile dermatomyositis, the most common form of childhood inflammatory myopathy...
An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activityEmily C Baechler
University of Minnesota Medical School, Minneapolis, MN 55455, USA
Mol Med 13:59-68. 2007..These data suggest that the IFN signature may be a useful marker for DM disease activity, and that sampling peripheral blood may be a more practical alternative to muscle biopsy for measuring this signature...
HLA polymorphisms in African Americans with idiopathic inflammatory myopathy: allelic profiles distinguish patients with different clinical phenotypes and myositis autoantibodiesTerrance P O'Hanlon
National Institute of Environmental Health Sciences, Bethesda, Maryland 20892, USA
Arthritis Rheum 54:3670-81. 2006..To investigate possible associations of HLA polymorphisms with idiopathic inflammatory myopathy (IIM) in African Americans, and to compare this with HLA associations in European American IIM patients with IIM...
International consensus on preliminary definitions of improvement in adult and juvenile myositisLisa G Rider
National Institute of Environmental Health Sciences, NIH, Bethesda, Maryland 20892, USA
Arthritis Rheum 50:2281-90. 2004..To use a core set of outcome measures to develop preliminary definitions of improvement for adult and juvenile myositis as composite end points for therapeutic trials...
Gene expression profiling in human autoimmunityEmily C Baechler
University of Minnesota Medical School, Minneapolis, MN 55455, USA
Immunol Rev 210:120-37. 2006..Here, we review the literature on gene profiling in human autoimmune diseases and provide perspective on the current state of the art...
International consensus guidelines for trials of therapies in the idiopathic inflammatory myopathiesChester V Oddis
University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Arthritis Rheum 52:2607-15. 2005
