Research Topics
Genomes and GenesSpecies | K G RasmussenSummaryAffiliation: Mayo Clinic Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Electroconvulsive therapy for phantom limb painK G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, USA
Pain 85:297-9. 2000..Both patients enjoyed substantial pain relief. In one case, phantom pain was still in remission 3.5 years after ECT. It is concluded that phantom limb patients who are refractory to multiple therapies may respond to ECT...
The effect of electroconvulsive therapy treatments on blood sugar in nondiabetic patientsKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
J ECT 21:232-4. 2005..We conclude that ECT does not have a clinically significant effect on blood sugar in non-diabetic patients...
The clinical utility of inhalational anesthesia with sevoflurane in electroconvulsive therapyKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
J ECT 21:239-42. 2005..In all patients, this method was well tolerated and offered distinct advantages compared with an intravenous induction agent. We conclude that ECT practitioners should keep this option in mind for select patients...
Anesthesia outcomes in a randomized double-blind trial of sevoflurane and thiopental for induction of general anesthesia in electroconvulsive therapyKeith G Rasmussen
Department of Psychiatry, Mayo Clinic, Rochester, MN 55905, USA
J ECT 23:236-8. 2007..Sevoflurane was associated with significantly better postictal orientation 20 minutes after the treatment. We conclude that inhalational anesthesia with sevoflurane presents a well-tolerated alternative for ECT anesthesia...
Patterns of psychotropic medication use among patients with severe depression referred for electroconvulsive therapy: data from the Consortium for Research on Electroconvulsive TherapyKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 22:116-23. 2006..Use of hypnotic agents and anticonvulsants was common. In conclusion, patients with severe depression referred for ECT with a unipolar depressive episode have high rates of psychotropic usage, much of which is inadequate...
Blood glucose before and after ECT treatments in Type 2 diabetic patientsKeith G Rasmussen
Department of Psychiatry, Mayo Clinic, Rochester, MN 55905, USA
J ECT 22:124-6. 2006..There were no cases of clinically significant rise or fall in blood glucose. We provide recommendations for management of diabetics during ECT...
Electrode placement and ictal EEG indices in electroconvulsive therapyKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
J Neuropsychiatry Clin Neurosci 19:453-7. 2007..These data provide a groundwork for future research on the neurophysiological aspects of ECT...
Seizure length with sevoflurane and thiopental for induction of general anesthesia in electroconvulsive therapy: a randomized double-blind trialKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 22:240-2. 2006..Absolute values for seizure duration with both sevoflurane and thiopental are well within typical ranges for those seen with the more commonly used methohexital as anesthetic...
Electroconvulsive therapy in patients with cavernous hemangiomasKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 22:272-3. 2006..We describe 3 patients with cavernous hemangiomas who received safe, uncomplicated ECT. We provide recommendations for ECT practice in such patients...
Antidepressant medication treatment failure does not predict lower remission with ECT for major depressive disorder: a report from the consortium for research in electroconvulsive therapyKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Clin Psychiatry 68:1701-6. 2007..To test whether antidepressant medication treatment failure predicts differential remission with electroconvulsive therapy (ECT) in nonpsychotic unipolar depression...
Patients who develop epilepsy during extended treatment with electroconvulsive therapyKeith G Rasmussen
Mayo Clinic, Department of Psychiatry and Psychology, 200 First St SW, Rochester, MN 55905, USA
Seizure 16:266-70. 2007..We describe some of the clinical challenges in this scenario and provide recommendations regarding continued use of ECT in the newly diagnosed epileptic patient...
ECT in patients with intracranial massesKeith G Rasmussen
Mayo Clinic Department of Psychiatry and Psychology, 200 First Street, Southwest, Rochester, MN 55905, USA
J Neuropsychiatry Clin Neurosci 19:191-3. 2007..None suffered any neurological deterioration during ECT. They provide recommendations for clinical practice with such patients...
QTc dispersion on the baseline ECG predicts arrhythmias during electroconvulsive therapyKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Acta Cardiol 62:345-7. 2007..Our objective in this study was to test the hypothesis that prolonged QTc dispersion predisposes to arrhythmias in electroconvulsive therapy (ECT)...
Electroconvulsive therapy in patients with multiple sclerosisKeith G Rasmussen
Department of Psychiatry and Psycology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 23:179-80. 2007..However, review of the literature and of our 3 cases does reveal that ECT can be used safely, at least in the short term. Long-term outcomes in such patients remain uncertain...
Serum sodium does not correlate with seizure length or seizure threshold in electroconvulsive therapyKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 23:175-6. 2007..We conclude that although it is ideal to have normal sodium values before ECT, mild abnormalities do not necessarily presage prolonged seizures or lower seizure thresholds in ECT...
Patients who inappropriately demand electroconvulsive therapyKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 23:109-13. 2007..We argue that some ECT patients are primarily motivated by the primary or secondary gain of being medical patients and that this needs to be considered by the clinician so as not to administer the treatments unnecessarily...
Data management and design issues in an unmasked randomized trial of electroconvulsive therapy for relapse prevention of severe depression: the consortium for research in electroconvulsive therapy trialKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 23:244-50. 2007..The purpose of this article is to describe the design characteristics and challenges of the trial and of our method of dealing with the lack of double-blind outcome assessment...
Relationship between somatization and remission with ECTKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
Psychiatry Res 129:293-5. 2004..In the less severely depressed group, high somatic anxiety and hypochondriasis predicted a low likelihood of sustained remission with ECT. In the more severely depressed group, these traits were not predictive of ECT outcome...
Electroconvulsive therapy in the management of chronic painKeith G Rasmussen
Mayo Clinic, Department of Psychiatry and Psychology, 200 First Street SW, Rochester, MN 55905, USA
Curr Pain Headache Rep 6:17-22. 2002..In this article, we review the literature on the use of ECT in pain patients, suggest possible neurobiologic bases for the efficacy of ECT in such patients, and conclude with our recommendations for current clinical practice...
Electroconvulsive therapy in the medically illKeith G Rasmussen
Departments of Psychiatry and Psychology, Mayo Medical School, Rochester, Minnesota, USA
Psychiatr Clin North Am 25:177-93. 2002..Although the available data consist largely of cases and case series, ECT is effective in treating psychopathology despite the comorbidity. With appropriate precautions and monitoring during and after ECT, complications can be minimized...
Some considerations in choosing electroconvulsive therapy versus transcranial magnetic stimulation for depressionKeith G Rasmussen
Department of Psychiatry, Mayo Clinic, Rochester, MN, USA
J ECT 27:51-4. 2011....
Electroconvulsive therapy and newer modalities for the treatment of medication-refractory mental illnessKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minn 55905, USA
Mayo Clin Proc 77:552-6. 2002..Besides providing therapeutic benefits, these 3 methods may help elucidate the pathophysiology of psychiatric illness...
Electroconvulsive therapy in palliative careKeith G Rasmussen
Department of Psychiatry and Psychology, Hospice and Palliative Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN55905, USA
Am J Hosp Palliat Care 28:375-7. 2011..We conclude that ECT should not be automatically discarded in patients receiving palliative care and offer some guidelines for its use in this population...
Serotonin transporter gene status and electroconvulsive therapy outcomes: a retrospective analysis of 83 patientsKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
J Clin Psychiatry 70:92-4. 2009..Carrier status for the long allele has been associated with a better response to serotonin reuptake inhibitor antidepressant medications in most studies...
Electroconvulsive therapy for patients with major depression and probable Lewy body dementiaKeith G Rasmussen
Department of Psychiatry and Psychology Mayo Clinic, Rochester, Minnesota, USA
J ECT 19:103-9. 2003..All of them enjoyed substantial relief from depression with ECT, which they tolerated well. It is concluded that ECT can be effective in treating depression associated with probable Lewy Body dementia...
Is baseline medication resistance associated with potential for relapse after successful remission of a depressive episode with ECT? Data from the Consortium for Research on Electroconvulsive Therapy (CORE)Keith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J Clin Psychiatry 70:232-7. 2009..To test whether pre-electroconvulsive therapy (ECT) medication resistance is associated with post-ECT relapse rates...
Lack of effect of ECT on Holter monitor recordings before and after treatmentKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
J ECT 20:45-7. 2004..There has been concern about persisting cardiac effects of electroconvulsive therapy (ECT). Several studies have analyzed Holter monitor recordings before and after ECT, and generally have found no significant effects...
Sham electroconvulsive therapy studies in depressive illness: a review of the literature and consideration of the placebo phenomenon in electroconvulsive therapy practiceKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
J ECT 25:54-9. 2009..In this report, the sham ECT literature is reviewed in detail, and the author discusses possible mechanisms by which sham-treated patients improved...
Orthostatic hemodynamic changes after electroconvulsive therapy treatmentsKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 24:134-6. 2008..We conclude that none of the commonly used perianesthetic medications or variations in ECT electrode placement are associated with orthostatic hypotension after ECT treatments...
Electroconvulsive therapy in patients taking steroid medication: should supplemental doses be given on the days of treatment?Keith G Rasmussen
Department of Psychiatry, Division of Cardiovascular Anesthesia, Mayo Clinic, Rochester, MN 55905, USA
J ECT 24:128-30. 2008..We conclude that use of "stress doses" of extra steroid medication is unnecessary in ECT practice and recommend that patients receive their usual morning dose of steroid before ECT treatments...
Remifentanil/Thiopental combination and seizure length in electroconvulsive therapyKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
J ECT 25:31-3. 2009..We conclude that if thiopental is used for anesthetic induction in electroconvulsive therapy in the dose range described herein, modest dose reduction and combination with remifentanil does not reliably prolong seizure duration...
Correlates of myalgia in electroconvulsive therapyKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 24:84-7. 2008..The results indicated that neither of these factors, nor dose of succinylcholine, correlated with myalgias. We conclude that dose adjustments to succinylcholine are unlikely to affect complaints of myalgias in ECT patients...
ECT in patients with psychopathology related to acute neurologic illnessKeith G Rasmussen
Mayo Clinic Dept of Psychiatry and Psychology, 200 First St SW, Rochester, MN 55905, USA
Psychosomatics 49:67-72. 2008..The authors provide recommendations for the approach to acutely ill neurologic patients with regard to the use of ECT...
Attempts to validate melancholic depression: some observations on modern research methodologyKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
Bull Menninger Clin 71:150-63. 2007..In this article, the author outlines what he believes are methodological problems that have been common in research studies to validate melancholia...
Electroconvulsive therapy and melancholia: review of the literature and suggestions for further studyKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
J ECT 27:315-22. 2011..Suggestions for future ECT/melancholia studies are offered...
The safety of electroconvulsive therapy and lithium in combination: a case series and review of the literatureTamara J Dolenc
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
J ECT 21:165-70. 2005..In this report, we describe 12 patients in whom the combination of lithium and ECT was deemed safe. We also provide a comprehensive review of published literature and provide detailed recommendations for clinical practice...
Electroconvulsive therapy for agitation in Alzheimer disease: a case seriesBruce Sutor
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 24:239-41. 2008..Electroconvulsive therapy (ECT) is a potential treatment option for patients who have failed medication trials...
Long-term maintenance ECT: a retrospective review of efficacy and cognitive outcomeJ Calvin Russell
Mayo Clinic, Rochester, Minnesota, USA
J ECT 19:4-9. 2003..We conclude that extended maintenance ECT is efficacious and well tolerated and reduces hospital use for a population of chronically depressed patients refractory to medication...
A randomized controlled trial comparing the memory effects of continuation electroconvulsive therapy versus continuation pharmacotherapy: results from the Consortium for Research in ECT (CORE) studyGlenn E Smith
Mayo Clinic, Department of Psychiatry and Psychology W11, 200 First Street, SW, Rochester, MN 55905, USA
J Clin Psychiatry 71:185-93. 2010..To compare the memory effects of continuation electroconvulsive therapy (C-ECT) versus continuation pharmacologic intervention (C-PHARM) at 12 and 24 weeks after completion of acute electroconvulsive therapy (ECT)...
Safety of electroconvulsive therapy in patients with unrepaired abdominal aortic aneurysm: report of 8 patientsPaul S Mueller
Division of General Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
J ECT 25:165-9. 2009..It is unclear whether ECT, which transiently, yet markedly, increases blood pressure and heart rate, can be safely performed in patients with AAA. We investigated the safety of ECT in patients with unrepaired AAA...
Effects of general anesthetic agents in adults receiving electroconvulsive therapy: a systematic reviewW Michael Hooten
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J ECT 24:208-23. 2008..Our secondary objective was to determine the differential effects of induction agents on emergence time, recovery time, and the occurrence of adverse cardiac events and drug effects...
Bradycardia and hypotension in a patient with severe aortic stenosis receiving electroconvulsive therapy dose titration for treatment of depressionBruce Sutor
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 24:281-2. 2008..We discuss practical considerations and risk reduction strategies when using ECT in patients with severe AS...
Changes in heart rate variability in response to treatment with electroconvulsive therapyVictor M Karpyak
Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J ECT 20:81-8. 2004..Heart rate variability (HRV) has proven predictive value for patients with cardiac and neurologic disorders and correlates with depression severity and treatment effects. Variable changes in HRV after ECT have been reported...
The safety of electroconvulsive therapy in patients with severe aortic stenosisPaul S Mueller
Division of General Internal Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Mayo Clin Proc 82:1360-3. 2007..Hence, ECT was safe in 10 patients with severe aortic stenosis treated at our institution. Our findings may be informative to clinicians who manage the care of patients with severe aortic stenosis who are undergoing ECT...
Nonconvulsive seizures in electroconvulsive therapy: further evidence of differential neurophysiological aspects of bitemporal versus bifrontal electrode placementPaul T Teman
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 22:46-8. 2006..Seizure threshold was also higher among the bifrontal patients. We hypothesize that this provides further evidence of differential neurophysiology of seizures induced with these 2 electrode placements...
Safety of electroconvulsive therapy in patients with asthmaP S Mueller
Divisions of General Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Neth J Med 64:417-21. 2006..Since ECT requires the administration of general anaesthesia, it is assumed that extra care should be taken with asthmatic patients before and during ECT. We sought to investigate the safety of ECT in asthmatic patients...
Electroconvulsive therapy in patients with epilepsyMary E Lunde
Mayo Clinic Department of Psychiatry, Rochester, MN 55905, USA
Epilepsy Behav 9:355-9. 2006..We conclude that most epileptic patients can be treated with ECT without dose adjustment in antiepileptic medications and provide general recommendations for safe use of ECT in this population...
Blood pressure before and after electroconvulsive therapy in hypertensive and nonhypertensive patientsScott M Albin
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 23:9-10. 2007..In neither group was there a statistically significant change in blood pressure with a course of ECT. We conclude that a course of ECT does not worsen blood pressure in hypertensive patients beyond the peritreatment period...
Seizure length in electroconvulsive therapy as a function of age, sex, and treatment numberJoseph J Rasimas
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 23:14-6. 2007..The biggest drop in seizure duration along a course of treatments occurs between the first and second treatments; beyond that, seizure duration remains relatively constant...
Electroconvulsive therapy in patients with cardiac pacemakers and implantable cardioverter defibrillatorsTamara J Dolenc
Department of Psychiatry and Psychology, Mayo Clinic Collage of Medicine, Rochester, Minnesota, USA
Pacing Clin Electrophysiol 27:1257-63. 2004..We conclude from this experience that with proper pre-ECT cardiac and pacemaker/defibrillator assessment, ECT can be safely and effectively administered to patients with an implanted cardiac device...
QTc dispersion in patients referred for electroconvulsive therapyM Leann Dodd
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 24:131-3. 2008..To determine the presence of possible risk factors for arrhythmias during electroconvulsive therapy (ECT) by assessing QTc dispersion on the baseline electrocardiogram...
Electroconvulsive therapy in a patient with glaucomaMargaret S Good
Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota 55905, USA
J ECT 20:48-9. 2004..Though further research would be helpful, this case provides evidence that in a glaucomatous patient controlled with medicines or surgery, ECT probably will not cause a significant rise in IOP...
Clinical applications of recent research on electroconvulsive therapyKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
Bull Menninger Clin 67:18-31. 2003..In this article, I review recent research that bears on these aspects of ECT practice. Additionally, I review some findings on the neurobiological effects of ECT...
Safety, efficacy, and effects on glycemic control of electroconvulsive therapy in insulin-requiring type 2 diabetic patientsPamela J Netzel
Section of Adult Psychiatry, Mayo Clinic, Rochester, Minnesota, USA
J ECT 18:16-21. 2002..CONCLUSIONS: Our findings refute previous reports of dangerous hyperglycemia or improved glycemic control due to ECT in insulin-requiring type 2 diabetes, and suggest that ECT is safe and efficacious in these patients...
Decisional capacity of severely depressed patients requiring electroconvulsive therapyMaria I Lapid
Department of Psychiatry and Psychology and dagger Department of Biostatistics, Mayo Clinic, Rochester, Minnesota, USA
J ECT 19:67-72. 2003..Education improved their decisional capacity. There is an endpoint beyond which additional educational intervention does not result in measurable improvement in decisional capacity...
ECT in patients with arachnoid cystsCandace Lynn Perry
Department of Psychiatry and Psychology, Division of Neuroradiology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 23:36-7. 2007..We describe the safe use of ECT in 6 patients with arachnoid cysts. We conclude that such lesions are probably not associated with increased morbidity in ECT but that neurological evaluation pretreatment is indicated...
Electroconvulsive therapy in patients taking monoamine oxidase inhibitorsTamara J Dolenc
Department of Psychiatry and Psychology, Mayo Clinic College of Medicine Rochester, Rochester, MN 55905, USA
J ECT 20:258-61. 2004..Furthermore, if there is otherwise a reason for continuing the MAOI, it can be continued during index ECT or initiated during maintenance ECT...
The safety of ECT in patients with chronic obstructive pulmonary diseaseKathryn M Schak
Dept of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
Psychosomatics 49:208-11. 2008..Electroconvulsive therapy (ECT) involves the administration of general anesthesia and assisted ventilation while the patient is apneic...
Morbidity and mortality in the use of electroconvulsive therapyGregory A Nuttall
Department of Anesthesiology, Mayo Clinic College of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
J ECT 20:237-41. 2004..There were 18 deaths within 30 days of the final treatment, none related to ECT. These data are concordant with those of other published large series, and we conclude that ECT is an extremely safe procedure...
Antidepressants and manic symptomsKeith G Rasmussen
Am J Psychiatry 165:263-4; author reply 264. 2008
Whole brain kindlingKeith G Rasmussen
J ECT 20:52. 2004
Research Grants
- COMPARING THREE ELECTRODE PLACEMENTS TO OPTIMIZE ECTKeith Rasmussen; Fiscal Year: 2005..The results of this study will promote more effective and safer treatment of the most severely ill depressed patients. ..
