Rajiv K Pruthi

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. ncbi request reprint Haemostatic efficacy and safety of bolus and continuous infusion of recombinant factor VIIa are comparable in haemophilia patients with inhibitors undergoing major surgery. Results from an open-label, randomized, multicenter trial
    Rajiv K Pruthi
    Comprehensive Hemophilia Center, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Thromb Haemost 98:726-32. 2007
  2. doi request reprint Review of the American College of Chest Physicians 2012 Guidelines for Anticoagulation Therapy and Prevention of Thrombosis
    Rajiv K Pruthi
    Division of Hematology, Department of Internal Medicine, Mayo Clinic Rochester, Rochester, MN, USA
    Semin Hematol 50:251-8. 2013
  3. doi request reprint Plasma von Willebrand factor multimer quantitative analysis by in-gel immunostaining and infrared fluorescent imaging
    Rajiv K Pruthi
    Special Coagulation Laboratory, Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester, MN 55905, USA
    Thromb Res 126:543-9. 2010
  4. ncbi request reprint Autoimmune factor VIII inhibitors
    R K Pruthi
    Department of Internal Medicine and Hematology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Curr Opin Hematol 6:314-22. 1999
  5. ncbi request reprint Molecular analysis in a patient with severe factor VII deficiency and an inhibitor: report of a novel mutation (S103G)
    Rajiv K Pruthi
    Special Coagulation Laboratory, Mayo Clinic, Rochester, MN 55905, USA
    Eur J Haematol 79:354-9. 2007
  6. ncbi request reprint A practical approach to genetic testing for von Willebrand disease
    Rajiv K Pruthi
    Department of Internal Medicine and Division of Hematology, Special Coagulation DNA Diagnostic Laboratory, Comprehensive Hemophilia Center, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 81:679-91. 2006
  7. ncbi request reprint Hemophilia: a practical approach to genetic testing
    Rajiv K Pruthi
    Department of Internal Medicine, Division of Hematology, Special Coagulation DNA Diagnostic Laboratory, and Comprehensive Hemophilia Center, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 80:1485-99. 2005
  8. ncbi request reprint Five things oculoplastic surgeons should know about the preoperative assessment of hemostasis
    Rajiv K Pruthi
    Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
    Ophthal Plast Reconstr Surg 18:396-401. 2002
  9. doi request reprint Health-related quality of life and patient satisfaction after global endometrial ablation for menorrhagia in women with bleeding disorders: a follow-up survey and systematic review
    Sherif A El-Nashar
    Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Obstet Gynecol 202:348.e1-7. 2010
  10. doi request reprint Comparison of complication rates of Hickman(®) catheters versus peripherally inserted central catheters in patients with acute myeloid leukemia undergoing induction chemotherapy
    Ming Y Lim
    Department of Internal Medicine, Mayo Clinic Rochester, Rochester, MN, USA
    Leuk Lymphoma 54:1263-7. 2013

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Haemostatic efficacy and safety of bolus and continuous infusion of recombinant factor VIIa are comparable in haemophilia patients with inhibitors undergoing major surgery. Results from an open-label, randomized, multicenter trial
    Rajiv K Pruthi
    Comprehensive Hemophilia Center, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Thromb Haemost 98:726-32. 2007
    ..Serious adverse events were related to continued or increased bleeding. In conclusion, haemostatic efficacy and safety of BI and CI of rFVIIa are comparable for the surgical management of haemophilia subjects with inhibitors...
  2. doi request reprint Review of the American College of Chest Physicians 2012 Guidelines for Anticoagulation Therapy and Prevention of Thrombosis
    Rajiv K Pruthi
    Division of Hematology, Department of Internal Medicine, Mayo Clinic Rochester, Rochester, MN, USA
    Semin Hematol 50:251-8. 2013
    ..The AT9 recommendations are presented with, if included, the AT8 recommendations in parenthesis for comparison purposes. ..
  3. doi request reprint Plasma von Willebrand factor multimer quantitative analysis by in-gel immunostaining and infrared fluorescent imaging
    Rajiv K Pruthi
    Special Coagulation Laboratory, Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester, MN 55905, USA
    Thromb Res 126:543-9. 2010
    ....
  4. ncbi request reprint Autoimmune factor VIII inhibitors
    R K Pruthi
    Department of Internal Medicine and Hematology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Curr Opin Hematol 6:314-22. 1999
    ..Future laboratory and clinical studies are necessary for advancement of pathophysiologic knowledge and therapeutic options for patients with this uncommon but clinically important disorder...
  5. ncbi request reprint Molecular analysis in a patient with severe factor VII deficiency and an inhibitor: report of a novel mutation (S103G)
    Rajiv K Pruthi
    Special Coagulation Laboratory, Mayo Clinic, Rochester, MN 55905, USA
    Eur J Haematol 79:354-9. 2007
    ..This mutation in the heterozygous form was also present in a mildly affected, unrelated patient. We also report on the natural history of an FVII inhibitor in the patient with severe FVII deficiency...
  6. ncbi request reprint A practical approach to genetic testing for von Willebrand disease
    Rajiv K Pruthi
    Department of Internal Medicine and Division of Hematology, Special Coagulation DNA Diagnostic Laboratory, Comprehensive Hemophilia Center, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 81:679-91. 2006
    ..This article provides a practical approach to utilization of genetic testing in vWD...
  7. ncbi request reprint Hemophilia: a practical approach to genetic testing
    Rajiv K Pruthi
    Department of Internal Medicine, Division of Hematology, Special Coagulation DNA Diagnostic Laboratory, and Comprehensive Hemophilia Center, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 80:1485-99. 2005
    ..This article provides a practical approach to using genetic testing for hemophilia A and B...
  8. ncbi request reprint Five things oculoplastic surgeons should know about the preoperative assessment of hemostasis
    Rajiv K Pruthi
    Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
    Ophthal Plast Reconstr Surg 18:396-401. 2002
  9. doi request reprint Health-related quality of life and patient satisfaction after global endometrial ablation for menorrhagia in women with bleeding disorders: a follow-up survey and systematic review
    Sherif A El-Nashar
    Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Obstet Gynecol 202:348.e1-7. 2010
    ..The purpose of this study was to describe health-related quality of life and satisfaction after global endometrial ablation in women with bleeding disorders and a systematic review of the literature...
  10. doi request reprint Comparison of complication rates of Hickman(®) catheters versus peripherally inserted central catheters in patients with acute myeloid leukemia undergoing induction chemotherapy
    Ming Y Lim
    Department of Internal Medicine, Mayo Clinic Rochester, Rochester, MN, USA
    Leuk Lymphoma 54:1263-7. 2013
    ..The choice of type of CVAD inserted into patients with newly diagnosed AML will depend on ease of catheter placement, cost, perception of frequency and severity of complications, and clinician preference...
  11. doi request reprint Therapy-related acute promyelocytic leukemia: observations relating to APL pathogenesis and therapy
    Michelle A Elliott
    Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Eur J Haematol 88:237-43. 2012
    ..Therapy-related APL is sensitive to standard therapy with no cases of resistance or relapse seen. The inferior OS of the t-APL was due to induction mortality, possibly reflecting prior therapy...
  12. doi request reprint Cancer-associated microangiopathic hemolytic anemia with thrombocytopenia: an important diagnostic consideration
    Michelle A Elliott
    Division of Hematology Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Eur J Haematol 85:43-50. 2010
    ..Recognition of cancer-associated microangiopathic hemolytic anemia with thrombocytopenia (CA-MHA) is paramount to avoid inappropriate PE therapy and delays in cancer-specific chemotherapy...
  13. ncbi request reprint Acquired von Willebrand's syndrome: a single institution experience
    Shaji Kumar
    Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Hematol 72:243-7. 2003
    ..AVWS may be more prevalent than has been appreciated; we estimate up to 0.04%. Awareness of the existence of AVWS is essential for diagnosis and appropriate management. Therapy of associated diseases may improve the bleeding disorder...
  14. doi request reprint Bacterial endocarditis and septic arthritis in a patient with severe hemophilia A: a case report
    Ruetima Titapiwatanakun
    Division of Pediatric Hematology and Oncology, Mayo Clinic, Rochester, MN 55905, USA
    J Pediatr Hematol Oncol 31:344-5. 2009
    ..Endocarditis and septic arthritis in patients with hemophilia are rare infectious complications but should be considered in patients with persistent bacteremia...
  15. doi request reprint Hemostatic management of an infant with severe hemophilia A and tetralogy of Fallot for cardiac bypass surgery
    Vilmarie Rodriguez
    Division of Pediatric Hematology and Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Pediatr Blood Cancer 55:1399-401. 2010
    ..Although cardiac surgery is successful, exposure to factor concentrates in severe hemophilia early in life might predispose a patient to inhibitor development...
  16. doi request reprint JAK2V617F mutation screening as part of the hypercoagulable work-up in the absence of splanchnic venous thrombosis or overt myeloproliferative neoplasm: assessment of value in a series of 664 consecutive patients
    Animesh Pardanani
    Division of Hematology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Mayo Clin Proc 83:457-9. 2008
    ..Our study also suggests that the natural history of a JAK2V617F-positive "occult" MPN might be different from that of a typical MPN...
  17. ncbi request reprint How to interpret and pursue an abnormal prothrombin time, activated partial thromboplastin time, and bleeding time in adults
    Arif H Kamal
    Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 82:864-73. 2007
    ....
  18. doi request reprint Novel splice site mutations in the gamma glutamyl carboxylase gene in a child with congenital combined deficiency of the vitamin K-dependent coagulation factors (VKCFD)
    Ruetima Titapiwatanakun
    Division of Pediatric Hematology Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Pediatr Blood Cancer 53:92-5. 2009
    ..Oral vitamin K supplementation resulted in partial resolution of proteins and complete resolution of bleeding...
  19. doi request reprint Pelvic pseudotumor and pseudoaneurysm in a pediatric patient with moderate hemophilia B: successful management with arterial embolization and surgical excision
    Riten Kumar
    Division of Pediatric Hematology Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Pediatr Blood Cancer 56:484-7. 2011
    ..He was successfully treated with Bead Block and coil embolization followed by surgical extirpation of the lesion 24 hr later...
  20. doi request reprint Transient neonatal acquired von Willebrand syndrome due to transplacental transfer of maternal monoclonal antibodies
    Amulya A Nageswara Rao
    Division of Pediatric Hematology Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Pediatr Blood Cancer 53:655-7. 2009
    ....
  21. ncbi request reprint Acquired von Willebrand disease
    Shaji Kumar
    Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
    Mayo Clin Proc 77:181-7. 2002
    ..Intravenous immunoglobulins have also shown some efficacy in the management of AvWD, especially cases associated with monoclonal gammopathies. Awareness of AvWD is essential for diagnosis and appropriate management...
  22. ncbi request reprint Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukaemia
    Gordon W Dewald
    Division of Laboratory Genetics, Mayo Clinic, Rochester, MN 55905, USA
    Br J Haematol 121:287-95. 2003
    ..Importantly, only CD38+ was significantly associated with high-risk FISH categories (+12, 11q- and 17p-) after adjustment for the effects of other variables...
  23. ncbi request reprint A highly-sensitive plasma von Willebrand factor ristocetin cofactor (VWF:RCo) activity assay by flow cytometry
    D Chen
    Special Coagulation Laboratory, Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Thromb Haemost 6:323-30. 2008
    ..However, current manual or automated VWF:RCo assay methods have relatively poor operating characteristics. Our goal was to develop and validate a simple, accurate, specific and sensitive platelet-based VWF:RCo assay...
  24. ncbi request reprint Intracranial haemorrhage as initial presentation of severe haemophilia B: case report and review of Mayo Clinic Comprehensive Hemophilia Center experience
    V Rodriguez
    Division of Pediatric Hematology Oncology, Mayo Clinic, Rochester, MN, USA
    Haemophilia 11:73-7. 2005
    ..His family history was negative for haemophilia. Review of our institutional experience as well as the literature indicates that intracranial bleeding as the initial presentation of haemophilia is rare...
  25. doi request reprint To circumcise or not to circumcise? Circumcision in patients with bleeding disorders
    V Rodriguez
    Division of Pediatric Hematology and Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Haemophilia 16:272-6. 2010
    ..Some of our patients had significant bleeding despite adequate factor replacement before and after the procedure. Parents and patients must be aware that bleeding risk is a possibility despite adequate factor replacement for hemostasis...
  26. doi request reprint Central venous access devices for paediatric patients with haemophilia: a single-institution experience
    R Titapiwatanakun
    Division of Pediatric Hematology and Oncology, Mayo Clinic, Rochester, Minnesota, USA
    Haemophilia 15:168-74. 2009
    ..The low rate of clinically apparent thrombosis reflects our practice of not screening for thrombosis. The low infection rate reflects our practice of using and reinforcing the aseptic technique...
  27. doi request reprint The new oral anticoagulants in clinical practice
    Wilson I Gonsalves
    Division of Hematology, Mayo Clinic, Rochester, MN 55906, USA
    Mayo Clin Proc 88:495-511. 2013
    ..Studies published in English were selected for inclusion in this review, as were additional articles identified from bibliographies...
  28. doi request reprint Outcomes of management of acute coronary syndrome in patients with congenital bleeding disorders: a single center experience and review of the literature
    Ming Y Lim
    Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Thromb Res 130:316-22. 2012
    ..Evidence-based guidelines for the management of acute coronary syndrome (ACS) in patients with congenital bleeding disorders are lacking and largely confined to case reports...
  29. doi request reprint Use of plasma exchange in patients with heparin-induced thrombocytopenia: a report of two cases and a review of the literature
    Elizabeth A Jaben
    Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine, Mayo Clinic, Rochester, Minnesota, USA
    J Clin Apher 26:219-24. 2011
    ..Following PE and subsequent CPB, neither patient had clinical or laboratory evidence of HIT. The literature regarding the use of PE for the treatment of complications of HIT and as prophylaxis before CPB is reviewed...
  30. doi request reprint Rituximab for refractory and or relapsing thrombotic thrombocytopenic purpura related to immune-mediated severe ADAMTS13-deficiency: a report of four cases and a systematic review of the literature
    Mischelle A Elliott
    Department of Internal Medicine Division of Hematology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Eur J Haematol 83:365-72. 2009
    ..Prospective studies are urgently needed to define the true efficacy and long-term safety of rituximab...
  31. doi request reprint Cardiovascular disease risk factors: prevalence and management in adult hemophilia patients
    Ming Y Lim
    Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Blood Coagul Fibrinolysis 22:402-6. 2011
    ..Collaborative efforts between primary care providers, cardiologists and hemophilia center specialists remain essential in managing these complex patients...
  32. ncbi request reprint Haemorrhage into a popliteal cyst: an unusual complication of haemophilia A
    V Rodriguez
    Comprehensive Hemophilia Center, Mayo Clinic, Rochester, Minnesota 55905, USA
    Haemophilia 8:725-8. 2002
    ..Imaging studies showed that by day 10 a popliteal cyst had ruptured, with diffusion of blood into the calf muscles. This case illustrates another possible bleeding complication in patients with a bleeding disorder and a popliteal cyst...
  33. ncbi request reprint Global endometrial ablation for menorrhagia in women with bleeding disorders
    Sherif A El-Nashar
    Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Obstet Gynecol 109:1381-7. 2007
    ..To evaluate the efficacy of global endometrial ablation in women with bleeding disorders who presented with menorrhagia...
  34. ncbi request reprint Thromboembolism in adults with acute lymphoblastic leukemia during induction with L-asparaginase-containing multi-agent regimens: incidence, risk factors, and possible role of antithrombin
    Michelle A Elliott
    Department of Internal Medicine, Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA
    Leuk Lymphoma 45:1545-9. 2004
    ..021). These observations merit further study to gain insight into disease and/or therapy-specific pathogenesis of TE in this population and call for the prospective evaluation of appropriate prophylactic interventions...
  35. ncbi request reprint Neutropenic colitis after treatment of acute myelogenous leukemia with idarubicin and cytosine arabinoside
    William J Hogan
    Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
    Mayo Clin Proc 77:760-2. 2002
    ..To determine the gastrointestinal toxic effects of idarubicin and cytosine arabinoside combination therapy in patients with newly diagnosed acute myelogenous leukemia (AML)...
  36. ncbi request reprint Hemostatic gene polymorphisms and the prevalence of thrombotic complications in polycythemia vera and essential thrombocythemia
    Vahid Afshar-Kharghan
    Thrombosis Research Section, Baylor College of Medicine, Houston, Texas, USA
    Blood Coagul Fibrinolysis 15:21-4. 2004
    ..In view of previous studies linking the presence of the PlA2 allele of GPIIIa to a higher risk for coronary artery thrombosis, our data have physiologic relevance. However, they need to be confirmed in a larger study...