Damon S Perez
Affiliation: Mayo Clinic
- Long, abundantly expressed non-coding transcripts are altered in cancerDamon S Perez
Division of Experimental Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic and Foundation, 200 First Street, S W, Rochester, MN 55905, USA
Hum Mol Genet 17:642-55. 2008..Although the function of these NCTs is currently unknown, our study indicates that they may play an important function in both normal cells and in cancer development...
- Gene expression changes associated with altered growth and differentiation in benzo[a]pyrene or arsenic exposed normal human epidermal keratinocytesDamon S Perez
Quantitative and Computational Toxicology Group, Center for Environmental Toxicology and Technology, Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA
J Appl Toxicol 28:491-508. 2008..Mechanistic studies with a subset of genes may allow the correlation of alterations in these molecular markers with chemical-specific blocks to differentiation in NHEK...
- Identification of long stress-induced non-coding transcripts that have altered expression in cancerJessica M Silva
Division of Experimental Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
Genomics 95:355-62. 2010..LSINCTs interestingly also have increased expression in a number of cancer-derived cell lines, indicating that the expression is increased in both, correlating cellular stress and cancer...
- Disabled-1 is a large common fragile site gene, inactivated in multiple cancersSarah McAvoy
Division of Experimental Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55902, USA
Genes Chromosomes Cancer 47:165-74. 2008..In summary, DAB1 is another gene that resides within an unstable CFS region and might play a role in human tumorigenesis. These data may provide further linkage between neurological development and cancer...
- Large common fragile site genes and cancerDavid I Smith
Division of Experimental Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, 200 First Street, S W, Rochester, MN 55905, United States
Semin Cancer Biol 17:31-41. 2007..In this review we will discuss the large common fragile site genes that have been identified to date, and the role that these genes appear to play both in cellular responses to stress and in the development of cancer...