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Genomes and GenesSpecies | Andre M OliveiraSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Frequency of USP6 rearrangements in myositis ossificans, brown tumor, and cherubism: molecular cytogenetic evidence that a subset of "myositis ossificans-like lesions" are the early phases in the formation of soft-tissue aneurysmal bone cystWilliam R Sukov
Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Skeletal Radiol 37:321-7. 2008..Several lesions show histologic features that may overlap with ABC, including myositis ossificans (MO), brown tumor, and cherubism. The objective of this study was to assess whether these lesions harbored USP6 rearrangements...- USP6 and CDH11 oncogenes identify the neoplastic cell in primary aneurysmal bone cysts and are absent in so-called secondary aneurysmal bone cystsAndre M Oliveira
Department of Pathology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
Am J Pathol 165:1773-80. 2004..By contrast, secondary ABC lack CDH11 and USP6 rearrangements, and although morphological mimics of primary ABC, appear to represent a non-specific morphological pattern of a diverse group of non-ABC neoplasms... - Aneurysmal bone cyst variant translocations upregulate USP6 transcription by promoter swapping with the ZNF9, COL1A1, TRAP150, and OMD genesAndre M Oliveira
Department of Pathology, Brigham and Women s Hospital, Boston, MA 02115, USA
Oncogene 24:3419-26. 2005..In summary, these studies show that USP6 oncogenic activation results from heterogeneous genomic mechanisms involving USP6 transcriptional upregulation by juxtaposition with ectopic promoters... - USP6 (Tre2) fusion oncogenes in aneurysmal bone cystAndre M Oliveira
Department of Pathology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
Cancer Res 64:1920-3. 2004..CDH11 is expressed strongly in bone, and our findings implicate a novel oncogenic mechanism in which deregulated USP6 transcription results from juxtaposition to the highly active CDH11 promoter... - KIT-negative gastrointestinal stromal tumors: proof of concept and therapeutic implicationsFabiola Medeiros
Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA
Am J Surg Pathol 28:889-94. 2004..Notably, some KIT-negative GISTs contain imatinib-sensitive KIT or PDGFRA mutations; therefore, patients with KIT-negative GISTs should not, a priori, be denied imatinib therapy... - Synovial sarcoma of the sellar regionBernd W Scheithauer
Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First St, SW, Rochester, MN 55905, USA
Neuro Oncol 9:454-9. 2007..Subtotal resection and radiosurgery proved to be efficacious. The spectrum of primary sellar region sarcomas is summarized... - KIT is an independent prognostic marker for pancreatic endocrine tumors: a finding derived from analysis of islet cell differentiation markersLizhi Zhang
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
Am J Surg Pathol 33:1562-9. 2009..These results indicate that KIT is a new and independent prognostic marker for PETs. The classification system derived from KIT and CK19 was able to predict clinical behavior of PET... - Correlation of IHC and FISH for ALK gene rearrangement in non-small cell lung carcinoma: IHC score algorithm for FISHEunhee S Yi
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA
J Thorac Oncol 6:459-65. 2011..Fluorescent in situ hybridization (FISH) is used to detect ALK+, but it is expensive and not routinely available. We explored the potential of an immunohistochemistry (IHC) scoring system as an affordable, accessible approach... - Successful treatment of a child with T/myeloid acute bilineal leukemia associated with TLX3/BCL11B fusion and 9q deletionJennifer L Oliveira
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
Pediatr Blood Cancer 56:467-9. 2011..Our patient has been in extended remission following ALL-based chemotherapy and a matched unrelated cord blood transplant. Inc... - Ependymal tumors with sarcomatous change ("ependymosarcoma"): a clinicopathologic and molecular cytogenetic studyFausto J Rodriguez
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
Am J Surg Pathol 32:699-709. 2008..Although rare, ependymal neoplasms must be included among the gliomas prone to undergo sarcomatous change and we propose the term "ependymosarcoma" for these tumors... - Pleomorphic liposarcoma: clinicopathologic analysis of 57 casesJason L Hornick
Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
Am J Surg Pathol 28:1257-67. 2004..By multivariate analysis, wide local excision or amputation and postoperative radiotherapy protected against local recurrence... - Applications of fluorescence in situ hybridization in cytopathology: a reviewAndre M Oliveira
Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Acta Cytol 49:587-94. 2005..Furthermore, due to its feasibility for virtually all types of cytologic specimens, a new and exciting era in both investigative and clinical cytopathology is expected... - Aneurysmal bone cyst: a neoplasm driven by upregulation of the USP6 oncogeneAndre M Oliveira
J Clin Oncol 24:e1; author reply e2. 2006 - Gains of COL1A1-PDGFB genomic copies occur in fibrosarcomatous transformation of dermatofibrosarcoma protuberansJared J Abbott
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
Mod Pathol 19:1512-8. 2006..Copy number of COL1A1-PDGFB fusion gene in the classic dermatofibrosarcoma protuberans areas does not seem to be a major predisposing mechanism for fibrosarcomatous transformation... - Genomic gains of COL1A1-PDFGB occur in the histologic evolution of giant cell fibroblastoma into dermatofibrosarcoma protuberansRicardo S Macarenco
CIPAX, Medicina Diagnostica, Sao Jose dos Campos SP, Brazil
Genes Chromosomes Cancer 47:260-5. 2008.... - Myxoinflammatory fibroblastic sarcoma showing t(2;6)(q31;p21.3) as a sole cytogenetic abnormalityCristiane M Ida
Division of Anatomic Pathology, Hospital das Clinicas C M I, Sao Paulo University School of Medicine, Sao Paulo, SP, Brazil
Cancer Genet Cytogenet 177:139-42. 2007..3) as the only cytogenetic abnormality. This finding is distinct from the two cases previously reported. Additional studies are needed to verify whether any of these chromosome rearrangements are involved recurrently in MIFS... - Primary synovial sarcoma of the mitral valveDylan V Miller
Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
Cardiovasc Pathol 14:331-3. 2005..The histopathologic diagnosis was supported by the immunohistochemical profile and the presence of the SYT-SSX1 fusion transcript identified by molecular genetic studies... - Frequency and characterization of HMGA2 and HMGA1 rearrangements in mesenchymal tumors of the lower genital tractFabiola Medeiros
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
Genes Chromosomes Cancer 46:981-90. 2007..The diagnostic usefulness of HMGA2 rearrangements to differentiate between AAM and other tumors of the lower genital tract may be limited due to the their low frequency... - HMGA2 rearrangements are rare in benign lipomatous lesions of the nervous systemFausto J Rodriguez
Acta Neuropathol 116:337-8. 2008 - Cytogenetic and molecular cytogenetic findings of intimal sarcomaHongying Zhang
Division of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Cancer Genet Cytogenet 179:146-9. 2007..Further studies are needed to determine whether the cytogenetic abnormalities found in this case are recurrent events for this poorly characterized malignancy... - Clonal cytogenetic abnormalities in Erdheim-Chester diseaseEneida F Vencio
Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
Am J Surg Pathol 31:319-21. 2007..However, additional studies are warranted to confirm whether the chromosomal abnormalities found in this case represent recurrent cytogenetic events... - Molecular prognostication for soft tissue sarcomas: are we ready yet?Andre M Oliveira
J Clin Oncol 22:4031-4. 2004 - Sustained complete remission of metastatic dermatofibrosarcoma protuberans with imatinib mesylateStefanos V Labropoulos
First Department of Medical Oncology, Hygeia Hospital, Marousi, Greece
Anticancer Drugs 16:461-6. 2005..We conclude that sustained complete remission of metastatic DFSP with specific FISH abnormalities involving the PDGFB locus can be obtained with imatinib mesylate with minimal toxicity for the patient... - Tumor suppressor genes in breast cancer: the gatekeepers and the caretakersAndre M Oliveira
Department of Laboratory Medicine and Pathology, Mayo Clinic and Mayo Foundation, Rochester, MN, USA
Am J Clin Pathol 124:S16-28. 2005..Other tumor suppressor genes of interest in breast cancer include the retinoblastoma gene (pRb), PTEN, p16, nm23, and maspin... - The prognostic significance of fibrosarcomatous transformation in dermatofibrosarcoma protuberansJared J Abbott
Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
Am J Surg Pathol 30:436-43. 2006..We demonstrate that FS change in DFSP is a form of tumor progression that carries an increased risk of metastasis over classic DFSP and is associated with gains of p53 mutations and increased proliferative activity... - Angiomyxofibromatous tumor of the falx cerebriFabiola Medeiros
Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
Am J Surg Pathol 30:545-7. 2006.... - Formation of the 12q14-q15 amplicon precedes the development of a well-differentiated liposarcoma arising from a nonchondroid pulmonary hamartomaSylvain Trahan
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
Am J Surg Pathol 30:1326-9. 2006.... - Cytogenetic and molecular genetic findings in dedifferentiated liposarcoma with neural-like whorling pattern and metaplastic bone formationRicardo S Macarenco
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
Cancer Genet Cytogenet 171:126-9. 2006..However, the specific cytogenetic and molecular determinants of these peculiar morphologic findings remain unknown... - Cytogenetic and molecular cytogenetic findings in dedifferentiated liposarcoma with neural-like whorling pattern and metaplastic bone formationRicardo S Macarenco
Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street NW, Rochester, MN 55905, USA
Cancer Genet Cytogenet 172:147-50. 2007..The specific cytogenetics and molecular determinants of these peculiar morphologic findings, however, remain unknown... - Primary sarcomas of the brain and spinal cord: a study of 18 casesAndre M Oliveira
Division of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota 55905, U.S.A
Am J Surg Pathol 26:1056-63. 2002..Most involve the cerebrum and show fibrous, "fibrohistiocytic," or no specific differentiation. The prognosis for high-grade sarcomas seems better than that for glioblastoma multiforme...