Samih H Nasr

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. pmc Proliferative glomerulonephritis with monoclonal IgG deposits recurs in the allograft
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Clin J Am Soc Nephrol 6:122-32. 2011
  2. doi request reprint Myeloproliferative neoplasms cause glomerulopathy
    Samar M Said
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Kidney Int 80:753-9. 2011
  3. doi request reprint Acquired glomerular lesions in patients with Down syndrome
    Samar M Said
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Hum Pathol 43:81-8. 2012
  4. doi request reprint Triamterene crystalline nephropathy
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Electronic address
    Am J Kidney Dis 63:148-52. 2014
  5. pmc Renal amyloidosis: origin and clinicopathologic correlations of 474 recent cases
    Samar M Said
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA
    Clin J Am Soc Nephrol 8:1515-23. 2013
  6. doi request reprint Bacterial infection-related glomerulonephritis in adults
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Division of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Kidney Int 83:792-803. 2013
  7. ncbi request reprint The diagnosis and characteristics of renal heavy-chain and heavy/light-chain amyloidosis and their comparison with renal light-chain amyloidosis
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Division of Anatomic Pathology, Hilton 10 20 200 First Street, SW, Rochester, Minnesota 55905, USA
    Kidney Int 83:463-70. 2013
  8. doi request reprint Immunotactoid glomerulopathy: clinicopathologic and proteomic study
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Nephrol Dial Transplant 27:4137-46. 2012
  9. doi request reprint Clinicopathologic correlations in multiple myeloma: a case series of 190 patients with kidney biopsies
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Kidney Dis 59:786-94. 2012
  10. doi request reprint Renal monoclonal immunoglobulin deposition disease: a report of 64 patients from a single institution
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Hilton 10 20, Rochester, MN 55905, USA
    Clin J Am Soc Nephrol 7:231-9. 2012

Collaborators

Detail Information

Publications38

  1. pmc Proliferative glomerulonephritis with monoclonal IgG deposits recurs in the allograft
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Clin J Am Soc Nephrol 6:122-32. 2011
    ..Proliferative GN with monoclonal IgG deposits (PGNMID) is a newly described entity resembling immune complex GN. Its potential to recur in the allograft is undefined...
  2. doi request reprint Myeloproliferative neoplasms cause glomerulopathy
    Samar M Said
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Kidney Int 80:753-9. 2011
    ..Greater awareness of this entity and larger studies are needed to define possible therapies...
  3. doi request reprint Acquired glomerular lesions in patients with Down syndrome
    Samar M Said
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Hum Pathol 43:81-8. 2012
    ..Renal biopsy is necessary to determine the type of glomerular lesion and appropriate treatment...
  4. doi request reprint Triamterene crystalline nephropathy
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Electronic address
    Am J Kidney Dis 63:148-52. 2014
    ..We report 2 cases of triamterene crystalline nephropathy, one of which initially was misdiagnosed as 2,8-dihydroxyadenine crystalline nephropathy. ..
  5. pmc Renal amyloidosis: origin and clinicopathologic correlations of 474 recent cases
    Samar M Said
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA
    Clin J Am Soc Nephrol 8:1515-23. 2013
    ..The kidney is the organ most commonly involved in systemic amyloidosis. This study reports the largest clinicopathologic series of renal amyloidosis...
  6. doi request reprint Bacterial infection-related glomerulonephritis in adults
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Division of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Kidney Int 83:792-803. 2013
    ..This review will address the current status of sporadic bacterial IRGN in adults...
  7. ncbi request reprint The diagnosis and characteristics of renal heavy-chain and heavy/light-chain amyloidosis and their comparison with renal light-chain amyloidosis
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Division of Anatomic Pathology, Hilton 10 20 200 First Street, SW, Rochester, Minnesota 55905, USA
    Kidney Int 83:463-70. 2013
    ..The accurate histological diagnosis of renal AH/AHL and distinction from AL may have important clinical and prognostic implications...
  8. doi request reprint Immunotactoid glomerulopathy: clinicopathologic and proteomic study
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Nephrol Dial Transplant 27:4137-46. 2012
    ..Immunotactoid glomerulopathy (ITG) is a rare glomerular disease. Here, we report the largest clinicopathologic series of ITG and define its proteomic profile...
  9. doi request reprint Clinicopathologic correlations in multiple myeloma: a case series of 190 patients with kidney biopsies
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Kidney Dis 59:786-94. 2012
    ..Renal involvement is common in multiple myeloma. In this study, we examined kidney biopsy findings in patients with multiple myeloma and correlated them with their clinical renal and hematologic characteristics...
  10. doi request reprint Renal monoclonal immunoglobulin deposition disease: a report of 64 patients from a single institution
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Hilton 10 20, Rochester, MN 55905, USA
    Clin J Am Soc Nephrol 7:231-9. 2012
    ..To better define the clinical-pathologic spectrum and prognosis of monoclonal immunoglobulin deposition disease (MIDD), this study reports the largest series...
  11. ncbi request reprint Crystalline nephropathy due to 2,8-dihydroxyadeninuria: an under-recognized cause of irreversible renal failure
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Nephrol Dial Transplant 25:1909-15. 2010
    ..Only rare cases of DHA nephrolithiasis have been reported from the USA. Herein, we report three American patients who developed DHA crystalline nephropathy leading to end-stage renal disease (ESRD) with recurrence in the allograft...
  12. doi request reprint IgA-dominant postinfectious glomerulonephritis: a new twist on an old disease
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Nephron Clin Pract 119:c18-25; discussion c26. 2011
    ..The pathogenetic mechanism of selective IgA deposition in patients with poststaphylococcal glomerulonephritis likely involves specific host responses to the inciting pathogen...
  13. doi request reprint Postinfectious glomerulonephritis in the elderly
    Samih H Nasr
    Mayo Clinic, Division of Anatomic Pathology, Hilton 10 20, 200 First Street, SW, Rochester, MN 55905, USA
    J Am Soc Nephrol 22:187-95. 2011
    ..Prognosis for these older patients is poor, with fewer than 25% recovering full renal function...
  14. pmc Fibrillary glomerulonephritis: a report of 66 cases from a single institution
    Samih H Nasr
    Mayo Clinic, Division of Anatomic Pathology, Hilton 10 20, 200 First Street SW, Rochester, MN 55905, USA
    Clin J Am Soc Nephrol 6:775-84. 2011
    ..Most previously reported cases were idiopathic. To better define the clinical-pathologic spectrum and prognosis, we report the largest single-center series with the longest follow-up...
  15. ncbi request reprint C3 glomerulonephritis: clinicopathological findings, complement abnormalities, glomerular proteomic profile, treatment, and follow-up
    Sanjeev Sethi
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Kidney Int 82:465-73. 2012
    ..Thus, C3GN results from diverse abnormalities of the alternative complement pathway leading to subsequent glomerular injury...
  16. pmc Laser microdissection and proteomic analysis of amyloidosis, cryoglobulinemic GN, fibrillary GN, and immunotactoid glomerulopathy
    Sanjeev Sethi
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Clin J Am Soc Nephrol 8:915-21. 2013
    ..Organized deposits are present in amyloidosis, fibrillary GN, and immunotactoid glomerulopathy. However, the constituents of the deposits are not known...
  17. pmc Mass spectrometry-based proteomic diagnosis of renal immunoglobulin heavy chain amyloidosis
    Sanjeev Sethi
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Clin J Am Soc Nephrol 5:2180-7. 2010
    ..We also describe the clinicopathologic findings of four problematic cases of renal Ig heavy chain amyloidosis that required LMD/MS proteomic analysis for accurate typing of the amyloid...
  18. pmc Laser microdissection and mass spectrometry-based proteomics aids the diagnosis and typing of renal amyloidosis
    Sanjeev Sethi
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Kidney Int 82:226-34. 2012
    ....
  19. doi request reprint Clinical features of patients with immunoglobulin light chain amyloidosis (AL) with vascular-limited deposition in the kidney
    Alfonso Eirin
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA
    Nephrol Dial Transplant 27:1097-101. 2012
    ..There was a preference for λ light chain in the D-AL that was not noted in the V-AL. Patients with D-AL in this study had a longer median survival but most of them were stem cell transplantation candidates...
  20. pmc Urinary albumin excretion patterns of patients with cast nephropathy and other monoclonal gammopathy-related kidney diseases
    Nelson Leung
    Division of Hematology, Mayo Clinic, Rochester, Minnesota 55901, USA
    Clin J Am Soc Nephrol 7:1964-8. 2012
    ....
  21. ncbi request reprint Membranous glomerulonephritis is a manifestation of IgG4-related disease
    Mariam P Alexander
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA
    Kidney Int 83:455-62. 2013
    ..4 mg/dl). Thus, MGN should be included in the spectrum of IgG4-RD and should be suspected in proteinuric IgG4-RD patients. Conversely, patients with MGN and an appropriate clinical history should be evaluated for IgG4-RD...
  22. doi request reprint C3 glomerulonephritis associated with monoclonal gammopathy: a case series
    Ladan Zand
    Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA
    Am J Kidney Dis 62:506-14. 2013
    ..Functional inhibition of the complement-regulating proteins may result from a monoclonal gammopathy...
  23. doi request reprint C1q deposition in the renal allograft: a report of 24 cases
    Samar M Said
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Mod Pathol 23:1080-8. 2010
    ..The rate of preceding infection and the prevalence of proteinuria seem to be similar to the renal transplant recipients in general. Most cases show mesangial hypercellularity or no glomerular changes on light microscopy...
  24. pmc Atypical postinfectious glomerulonephritis is associated with abnormalities in the alternative pathway of complement
    Sanjeev Sethi
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Kidney Int 83:293-9. 2013
    ..Hence, the sequela is continual glomerular deposition of complement factors with resultant inflammation and development of an 'atypical' postinfectious glomerulonephritis...
  25. doi request reprint Monoclonal gammopathy of renal significance: when MGUS is no longer undetermined or insignificant
    Nelson Leung
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA
    Blood 120:4292-5. 2012
    ....
  26. pmc Low- and high-molecular-weight urinary proteins as predictors of response to rituximab in patients with membranous nephropathy: a prospective study
    Maria V Irazabal
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN, USA
    Nephrol Dial Transplant 28:137-46. 2013
    ..Selective urinary biomarkers have been considered superior to total proteinuria in predicting response to treatment and outcome in patients with membranous nephropathy (MN)...
  27. doi request reprint How I treat amyloidosis: the importance of accurate diagnosis and amyloid typing
    Nelson Leung
    Division of Nephrology and Hypertension, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Blood 120:3206-13. 2012
    ....
  28. pmc Proliferative glomerulonephritis secondary to dysfunction of the alternative pathway of complement
    Sanjeev Sethi
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Clin J Am Soc Nephrol 6:1009-17. 2011
    ..A recently described entity referred to as GN with C3 deposition (GN-C3) bears many similarities to DDD. The purpose of this study was to evaluate AP function in cases of GN-C3...
  29. doi request reprint Renal crescentic alpha heavy chain deposition disease: a report of 3 cases and review of the literature
    Mariam P Alexander
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Am J Kidney Dis 58:621-5. 2011
    ..In this report, we describe 3 additional cases of α HCDD, all with a crescentic pattern of injury and one of which was associated with cutis laxa. We compare their clinicopathologic features with all previously reported cases of HCDD...
  30. pmc Utility of urine eosinophils in the diagnosis of acute interstitial nephritis
    Angela K Muriithi
    Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, Department of Laboratory Medicine and Pathology Mayo Clinic, Rochester, Minnesota
    Clin J Am Soc Nephrol 8:1857-62. 2013
    ..Urine eosinophils (UEs) have been shown to correlate with acute interstitial nephritis (AIN) but the four largest series that investigated the test characteristics did not use kidney biopsy as the gold standard...
  31. ncbi request reprint Membranous nephropathy with crescents: a series of 19 cases
    Erika F Rodriguez
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
    Am J Kidney Dis 64:66-73. 2014
    ..Only rare cases of crescentic MN without ANCA or anti-GBM have been reported...
  32. pmc A novel mutation of LAMB2 in a multigenerational mennonite family reveals a new phenotypic variant of Pierson syndrome
    Brian G Mohney
    Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Ophthalmology 118:1137-44. 2011
    ..To describe a novel laminin β-2 (LAMB2) mutation associated with nephrotic syndrome and severe retinal disease without microcoria in a large, multigenerational family with Pierson syndrome...
  33. doi request reprint Membranoproliferative glomerulonephritis associated with autoimmune diseases
    Ladan Zand
    Mayo Clinic, Rochester, MN, USA
    J Nephrol 27:165-71. 2014
    ..In summary, this study describes the clinical features, renal biopsy findings, laboratory evaluation, treatment and prognosis of MPGN associated with autoimmune diseases. ..
  34. pmc Diagnosis of IgG4-related tubulointerstitial nephritis
    Yassaman Raissian
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 1 Street SW, Rochester, MN 55905, USA
    J Am Soc Nephrol 22:1343-52. 2011
    ..When the disease manifests in the kidney, our data support diagnostic criteria that can distinguish IgG4-TIN from other types of TIN...
  35. doi request reprint Diagnosis and treatment of glomerular diseases in elderly patients
    Qi Qian
    Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN and Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Electronic address
    Adv Chronic Kidney Dis 21:228-46. 2014
    ..We provide a comprehensive review and update of the diagnosis and treatment of glomerular diseases in the elderly. ..
  36. doi request reprint Myeloma-related kidney disease
    Nelson Leung
    Division of Nephrology and Hypertension, and Hematology, Mayo Clinic, Rochester, MN and Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN Electronic address
    Adv Chronic Kidney Dis 21:36-47. 2014
    ..In some cases, direct invasion by myeloma cells and/or bone marrow cells can also result in kidney injury. A kidney biopsy can help distinguish the various myeloma-related kidney diseases and aid in the treatment plan. ..
  37. pmc Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity
    Katharina Hopp
    Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Clin Invest 122:4257-73. 2012
    ..Altogether, this study highlights the role that in trans variants at the disease locus can play in phenotypic modification of dominant diseases and provides a truly orthologous PKD1 model, optimal for therapeutic testing...
  38. doi request reprint Myoglobin-associated acute kidney injury in the setting of ciprofloxacin administration
    Qi Qian
    Department of Medicine, Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Am J Kidney Dis 59:462-6. 2012
    ..We present a case of myoglobin-associated kidney failure in the setting of repeated ciprofloxacin administration in a lung transplant patient. Kidney biopsy was critical to establishing the diagnosis and avoiding future exposure...