William G Morice

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. ncbi request reprint Distinct bone marrow findings in T-cell granular lymphocytic leukemia revealed by paraffin section immunoperoxidase stains for CD8, TIA-1, and granzyme B
    William G Morice
    Division of Hematopathology, Mayo Clinic, Rochester, MN 55905, USA
    Blood 99:268-74. 2002
  2. ncbi request reprint The expression of the novel cytotoxic protein granzyme M by large granular lymphocytic leukaemias of both T-cell and NK-cell lineage: an unexpected finding with implications regarding the pathobiology of these disorders
    William G Morice
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Br J Haematol 137:237-9. 2007
  3. doi request reprint Novel immunophenotypic features of marrow lymphoplasmacytic lymphoma and correlation with Waldenström's macroglobulinemia
    William G Morice
    Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Mod Pathol 22:807-16. 2009
  4. ncbi request reprint Diffuse large B-cell lymphoma with distinctive patterns of splenic and bone marrow involvement: clinicopathologic features of two cases
    William G Morice
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Mod Pathol 18:495-502. 2005
  5. doi request reprint Predictive value of blood and bone marrow flow cytometry in B-cell lymphoma classification: comparative analysis of flow cytometry and tissue biopsy in 252 patients
    William G Morice
    Division of Hematopathology, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 83:776-85. 2008
  6. ncbi request reprint Demonstration of aberrant T-cell and natural killer-cell antigen expression in all cases of granular lymphocytic leukaemia
    William G Morice
    Division of Hematopathology, Mayo Clinic, Rochester, MN 55905, USA
    Br J Haematol 120:1026-36. 2003
  7. pmc B-cell count and survival: differentiating chronic lymphocytic leukemia from monoclonal B-cell lymphocytosis based on clinical outcome
    Tait D Shanafelt
    Mayo Clinic, Rochester, MN, USA
    Blood 113:4188-96. 2009
  8. pmc CD5-positive chronic B-cell lymphoproliferative disorders: diagnosis and prognosis of a heterogeneous disease entity
    Roxana S Dronca
    Division of Hematology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cytometry B Clin Cytom 78:S35-41. 2010
  9. ncbi request reprint CD5+ B-cell lymphoproliferative disorders: Beyond chronic lymphocytic leukemia and mantle cell lymphoma
    Dragan Jevremovic
    Division of Hematopathology, Mayo Clinic, 200 1 st Street SW, Hilton 8200, Rochester, MN 55905, USA
    Leuk Res 34:1235-8. 2010
  10. ncbi request reprint Inflammatory pseudotumor of the spleen associated with a clonal Epstein-Barr virus genome. Case report and review of the literature
    Jason T Lewis
    Dept of Pathology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Am J Clin Pathol 120:56-61. 2003

Detail Information

Publications35

  1. ncbi request reprint Distinct bone marrow findings in T-cell granular lymphocytic leukemia revealed by paraffin section immunoperoxidase stains for CD8, TIA-1, and granzyme B
    William G Morice
    Division of Hematopathology, Mayo Clinic, Rochester, MN 55905, USA
    Blood 99:268-74. 2002
    ..These findings clarify the bone marrow histopathology of T-cell GLL and provide an additional tool by which the discrete, abnormal lymphocyte population required for a diagnosis of T-cell GLL can be identified...
  2. ncbi request reprint The expression of the novel cytotoxic protein granzyme M by large granular lymphocytic leukaemias of both T-cell and NK-cell lineage: an unexpected finding with implications regarding the pathobiology of these disorders
    William G Morice
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Br J Haematol 137:237-9. 2007
    ..These unexpected results suggest commonality between T- and NK-LGL, providing further support to the notion that T-LGL is a disorder of dysregulated, chronically stimulated, adaptive cytotoxic T-cells...
  3. doi request reprint Novel immunophenotypic features of marrow lymphoplasmacytic lymphoma and correlation with Waldenström's macroglobulinemia
    William G Morice
    Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Mod Pathol 22:807-16. 2009
    ..Apart from this, no other pathological correlates of the clinical or laboratory features of symptomatic Waldenström's macroglobulinemia were identified...
  4. ncbi request reprint Diffuse large B-cell lymphoma with distinctive patterns of splenic and bone marrow involvement: clinicopathologic features of two cases
    William G Morice
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Mod Pathol 18:495-502. 2005
    ....
  5. doi request reprint Predictive value of blood and bone marrow flow cytometry in B-cell lymphoma classification: comparative analysis of flow cytometry and tissue biopsy in 252 patients
    William G Morice
    Division of Hematopathology, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 83:776-85. 2008
    ..To study the effectiveness of peripheral blood (PB) and bone marrow flow cytometric immunophenotyping (FCIP) in predicting the histologic B-cell lymphoma type...
  6. ncbi request reprint Demonstration of aberrant T-cell and natural killer-cell antigen expression in all cases of granular lymphocytic leukaemia
    William G Morice
    Division of Hematopathology, Mayo Clinic, Rochester, MN 55905, USA
    Br J Haematol 120:1026-36. 2003
    ..These studies delineate the unique immunophenotypic features diagnostic of T-GLL and provide strong evidence that NK-GLL, like T-GLL, represents a clonal lymphoproliferative disorder...
  7. pmc B-cell count and survival: differentiating chronic lymphocytic leukemia from monoclonal B-cell lymphocytosis based on clinical outcome
    Tait D Shanafelt
    Mayo Clinic, Rochester, MN, USA
    Blood 113:4188-96. 2009
    ..Using clinically relevant criteria to distinguish between monoclonal B-cell lymphocytosis (MBL) and CLL could minimize patient distress caused by labeling asymptomatic people at low risk for adverse clinical consequences as having CLL...
  8. pmc CD5-positive chronic B-cell lymphoproliferative disorders: diagnosis and prognosis of a heterogeneous disease entity
    Roxana S Dronca
    Division of Hematology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cytometry B Clin Cytom 78:S35-41. 2010
    ..e. CD5+B-CLPD) are poorly defined...
  9. ncbi request reprint CD5+ B-cell lymphoproliferative disorders: Beyond chronic lymphocytic leukemia and mantle cell lymphoma
    Dragan Jevremovic
    Division of Hematopathology, Mayo Clinic, 200 1 st Street SW, Hilton 8200, Rochester, MN 55905, USA
    Leuk Res 34:1235-8. 2010
    ..Applying strict flow cytometry criteria, using genetic studies, and deferring to a lymph node/tissue diagnosis in non-classical cases are critical for accurate diagnosis and classification of CD5+ B-cell LPD...
  10. ncbi request reprint Inflammatory pseudotumor of the spleen associated with a clonal Epstein-Barr virus genome. Case report and review of the literature
    Jason T Lewis
    Dept of Pathology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Am J Clin Pathol 120:56-61. 2003
    ..The presence of clonal EBV DNA suggests some splenic IPTs may be true neoplasms...
  11. pmc Bone marrow histopathology in POEMS syndrome: a distinctive combination of plasma cell, lymphoid, and myeloid findings in 87 patients
    Linda N Dao
    Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Blood 117:6438-44. 2011
    ....
  12. pmc Brief report: natural history of individuals with clinically recognized monoclonal B-cell lymphocytosis compared with patients with Rai 0 chronic lymphocytic leukemia
    Tait D Shanafelt
    Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 27:3959-63. 2009
    ..The natural history of clinically identified MBL is unclear. The goal of this study was to explore the outcome of patients with MBL relative to that of individuals with Rai stage 0 chronic lymphocytic leukemia (CLL)...
  13. ncbi request reprint Expression of cytolytic lymphocyte-associated antigens in pulmonary lymphomatoid granulomatosis
    William G Morice
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Clin Pathol 118:391-8. 2002
    ....
  14. ncbi request reprint The immunophenotypic attributes of NK cells and NK-cell lineage lymphoproliferative disorders
    William G Morice
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Clin Pathol 127:881-6. 2007
    ....
  15. ncbi request reprint Spectrum of bone marrow findings in patients with angioimmunoblastic T-cell lymphoma
    Karen L Grogg
    Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Br J Haematol 137:416-22. 2007
    ..In two cases, these changes obscured the presence of BM involvement by AITL. The spectrum of BM findings in AITL patients is important to recognise for early and accurate diagnosis in this disease...
  16. ncbi request reprint Human leucocyte antigen class I and killer immunoglobulin-like receptor expression patterns in T-cell large granular lymphocyte leukaemia
    Grzegorz S Nowakowski
    Department of Hematology, Mayo Clinic, Rochester, MN 55905, USA
    Br J Haematol 128:490-2. 2005
    ..Cytopenias occurred in all five 'mismatch' patients but not in two patients with 'match', suggesting that KIR/HLA-I mismatch may contribute to the suppression of haematopoiesis...
  17. ncbi request reprint A comparison of morphologic features, flow cytometry, TCR-Vbeta analysis, and TCR-PCR in qualitative and quantitative assessment of peripheral blood involvement by Sézary syndrome
    William G Morice
    Division of Hematopathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Clin Pathol 125:364-74. 2006
    ....
  18. ncbi request reprint Clinical features in T-cell vs. natural killer-cell variants of large granular lymphocyte leukemia
    Michelle A Neben
    Division of Hematology and Internal Medicine Division of Hematopathology, Mayo Clinic, Mayo Medical School, Rochester, MN 55905, USA
    Eur J Haematol 71:263-5. 2003
    ....
  19. pmc MBL or CLL: which classification best categorizes the clinical course of patients with an absolute lymphocyte count >or= 5 x 10(9) L(-1) but a B-cell lymphocyte count <5 x 10(9) L(-1)?
    Tait D Shanafelt
    Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, United States
    Leuk Res 32:1458-61. 2008
    ..In contrast, CD38 predicted TTT (p=0.02) regardless of the proposed new classification. Molecular characteristics of the leukemic clone are a better predictor of progression than an arbitrary ALC or B lymphocyte count threshold...
  20. ncbi request reprint An unusual case of leukemic mantle cell lymphoma with a blastoid component showing loss of CD5 and aberrant expression of CD10
    William G Morice
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Clin Pathol 122:122-7. 2004
    ..This case illustrates the phenotypic heterogeneity of MCL and underscores the need for histopathologic correlation and, in some instances, ancillary genetic studies to accurately classify B-cell lymphomas...
  21. doi request reprint Immunophenotypic attributes of benign peripheral blood gammadelta T cells and conditions associated with their increase
    Anja C Roden
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN55905, USA
    Arch Pathol Lab Med 132:1774-80. 2008
    ..In comparison to alphabeta T cells, little is known about the immunophenotype of healthy peripheral blood gammadelta T cells or about conditions associated with expansion of this usually minor T-cell subset...
  22. ncbi request reprint Flow cytometric assessment of T-cell chronic lymphoproliferative disorders
    Francois M Cady
    Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA
    Clin Lab Med 27:513-32, vi. 2007
    ....
  23. ncbi request reprint Clinical significance of monoclonal B cells in cerebrospinal fluid
    Grzegorz S Nowakowski
    Division of Hematology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Cytometry B Clin Cytom 63:23-7. 2005
    ..Although flow cytometry is increasingly used to detect a monoclonal B-cell population in the CSF, the significance of this finding in the absence of morphologically identifiable malignant cells is unknown...
  24. ncbi request reprint Flow cytometric assessment of TCR-Vbeta expression in the evaluation of peripheral blood involvement by T-cell lymphoproliferative disorders: a comparison with conventional T-cell immunophenotyping and molecular genetic techniques
    William G Morice
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Clin Pathol 121:373-83. 2004
    ..TCR-Vbeta flow cytometric analysis is a powerful clinical laboratory tool that can be used to aid in the rapid diagnosis of peripheral blood involvement by T-cell malignant neoplasms...
  25. ncbi request reprint Chronic basophilic leukemia: a distinct clinico-pathologic entity?
    Animesh D Pardanani
    Divisions of Hematology and Internal Medicine, Hematopathology, Mayo Clinic, Rochester, MN 55905, USA
    Eur J Haematol 71:18-22. 2003
    ..We sought to better define a group of rare and poorly understood myeloproliferative disorders that are characterized by prominent chronic basophilia in the absence of the Philadelphia chromosome (Ph) or its molecular equivalent...
  26. doi request reprint Establishment and characterization of a novel Waldenstrom macroglobulinemia cell line, MWCL-1
    Lucy S Hodge
    Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN, USA
    Blood 117:e190-7. 2011
    ..The genetic, immunophenotypic, and biologic data presented here confirm the validity of the MWCL-1 cell line as a representative model of WM...
  27. ncbi request reprint Comparison of fluorescence in situ hybridization, p57 immunostaining, flow cytometry, and digital image analysis for diagnosing molar and nonmolar products of conception
    Benjamin R Kipp
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Am J Clin Pathol 133:196-204. 2010
    ..These data suggest that the combination of p57 and FISH seems to be the best ancillary testing strategy to aid pathologists in the appropriate identification of CM, PM, and HA in POC specimens...
  28. doi request reprint Immunohistochemical phenotyping of plasma cells in lymphoplasmacytic lymphoma/Waldenström's macroglobulinemia is comparable to flow cytometric techniques
    Matthew T Howard
    Division of Hematopathology, Mayo Clinic, Rochester, Minnesota, USA
    Clin Lymphoma Myeloma Leuk 11:96-8. 2011
    ..The results indicate that immunohistochemistry yields results comparable to flow cytometry, and suggests that using both modalities in parallel compensates for the shortcomings of each...
  29. ncbi request reprint Loss of blast heterogeneity in myelodysplastic syndrome and other chronic myeloid neoplasms
    Dragan Jevremovic
    From the Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester, Rochester, MN
    Am J Clin Pathol 142:292-8. 2014
    ..However, its use has been limited due to complexity and cost restraints. The goal of this study is to attempt a simpler approach to flow cytometry immunophenotyping in myeloid neoplasms...
  30. pmc Diagnosis and management of Waldenström macroglobulinemia: Mayo stratification of macroglobulinemia and risk-adapted therapy (mSMART) guidelines
    Stephen M Ansell
    Division of Hematology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Mayo Clin Proc 85:824-33. 2010
    ..Autologous stem cell transplant should be considered in all eligible patients with relapsed disease...
  31. pmc Remission of disseminated cancer after systemic oncolytic virotherapy
    Stephen J Russell
    Department of Molecular Medicine, Mayo Clinic, Rochester, MN Division of Hematology, Mayo Clinic, Rochester, MN
    Mayo Clin Proc 89:926-33. 2014
    ..Toxicities resolved within the first week after therapy. Oncolytic viruses offer a promising new modality for the targeted infection and destruction of disseminated cancer. ..
  32. ncbi request reprint Hemophagocytosis in a patient with chronic lymphocytic leukemia and histoplasmosis
    Ravi D Rao
    Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
    Mayo Clin Proc 77:287-90. 2002
    ..Clinical manifestations include signs and symptoms of immune activation and decreased peripheral blood cell counts. This condition is often underdiagnosed because clinicians are unfamiliar with it...
  33. doi request reprint Anti-CD20 monoclonal antibody therapy in multiple myeloma
    Prashant Kapoor
    Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA
    Br J Haematol 141:135-48. 2008
    ..Further large-scale clinical trials are therefore needed to establish the role of this promising strategy in the treatment of myeloma...
  34. doi request reprint The clinical and laboratory approach to the CD5/CD10 negative B-cell chronic lymphoproliferative leukemias
    Curtis A Hanson
    Am J Hematol 83:347-8. 2008
  35. ncbi request reprint Bone marrow histopathology in peripheral T-cell lymphomas
    Ahmet Dogan
    Department of Histopathology, University College London, London, UK
    Br J Haematol 127:140-54. 2004
    ..In this article we review the histopathology of bone marrow biopsy in PTCL within the context of the new WHO classification...