Research Topics
| Timothy I MorgenthalerSummaryAffiliation: Mayo Clinic Country: USA Publications
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Detail Information
Publications
Treatment of complex sleep apnea syndromeTomasz J Kuzniar
Timothy I Morgenthaler, MD Center for Sleep Medicine, Mayo Clinic, 200 First Street, Rochester, MN 55905, USA
Curr Treat Options Neurol 10:336-41. 2008..There is anecdotal evidence that CompSAS may be successfully treated using combined PAP therapy with oxygen, carbon dioxide, or the addition of dead space, but data are not sufficient to routinely recommend these methods...
Using a framework for spread of best practices to implement successful venous thromboembolism prophylaxis throughout a large hospital systemTimothy I Morgenthaler
Mayo Clinic, Rochester, MN 55902, USA
Am J Med Qual 27:30-8. 2012..Use of an explicit, well-constructed spread plan allows for an orderly management of diffusion of best practices...
Complex sleep apnea syndrome: is it a unique clinical syndrome?Timothy I Morgenthaler
Mayo Clinic Sleep Disorders Center, Division of Pulmonary and Critical Care Medicine, 200 First Street SW, Rochester, MN 55905, USA
Sleep 29:1203-9. 2006....
Early anticoagulation is associated with reduced mortality for acute pulmonary embolismSean B Smith
Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
Chest 137:1382-90. 2010..Acute pulmonary embolism (PE) may be rapidly fatal if not diagnosed and treated. IV heparin reduces mortality and recurrence of PE, but the relationship between survival and timing of anticoagulation has not been extensively studied...
Effect of a targeted obstructive sleep apnea consult to improve access and quality at a sleep disorders centerTimothy I Morgenthaler
Mayo Clinic Sleep Disorders Center, 200 First Street SW, Rochester, MN 55905, USA
J Clin Sleep Med 2:49-56. 2006....
The quest for stability in an unstable world: adaptive servoventilation in opioid induced complex sleep apnea syndromeTimothy I Morgenthaler
Mayo Clinic Center for Sleep Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, USA
J Clin Sleep Med 4:321-3. 2008
Practice parameters for the use of autotitrating continuous positive airway pressure devices for titrating pressures and treating adult patients with obstructive sleep apnea syndrome: an update for 2007. An American Academy of Sleep Medicine reportTimothy I Morgenthaler
Mayo Clinic, Rochester MN, USA
Sleep 31:141-7. 2008....
Practice parameters for the treatment of narcolepsy and other hypersomnias of central originTimothy I Morgenthaler
Mayo Clinic, Rochester MN, USA
Sleep 30:1705-11. 2007....
Practice parameters for the clinical evaluation and treatment of circadian rhythm sleep disorders. An American Academy of Sleep Medicine reportTimothy I Morgenthaler
Mayo Sleep Disorders Center, Mayo Clinic, Rochester, MN, USA
Sleep 30:1445-59. 2007..Stimulants may be indicated to improve alertness in JLD and SWD (Option) but may have risks that must be weighed prior to use. Modafinil may be indicated to improve alertness during the night shift for patients with SWD (Guideline)...
Care of patients with acute pulmonary emboli: a clinical review with cardiovascular focusJeffrey B Geske
Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Expert Rev Cardiovasc Ther 10:235-50. 2012..In risk-stratified hemodynamically stable patients, an outpatient management strategy inclusive of therapeutic anticoagulation and careful clinical follow-up may be appropriate...
Management plan to reduce risks in perioperative care of patients with presumed obstructive sleep apnea syndromeBhargavi Gali
Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
J Clin Sleep Med 3:582-8. 2007..We initiated a protocol designed to screen patients preoperatively and monitor them postoperatively. The goal was to identify patients who were at risk for oxygen desaturation after discharge from the postanesthesia recovery room (PACU)...
Efficacy of adaptive servoventilation in treatment of complex and central sleep apnea syndromesJoanne Shirine Allam
Division of Pulmonary and Critical Care Medicine and Mayo Clinic Sleep Disorders Center, 200 First St SW, Rochester, MN 55905, USA
Chest 132:1839-46. 2007..Treatment of CompSAS or central sleep apnea (CSA) syndrome with adaptive servoventilation (ASV) is now an option, but no large series exist describing the application and effectiveness of ASV...
Nocturnal moaning and groaning-catathrenia or nocturnal vocalizationsAdnan A Abbasi
Center for Sleep Medicine, Mayo Clinic, Rochester, MN 55901, USA
Sleep Breath 16:367-73. 2012..We undertook a study at our center on patients diagnosed with catathrenia, to evaluate the characteristic features of these events and their response to continuous positive airway pressure (CPAP) treatment...
Risk factors associated with delayed diagnosis of acute pulmonary embolismSean B Smith
Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55901, USA
J Emerg Med 42:1-6. 2012..Prompt diagnosis and treatment of acute pulmonary embolism (PE) is essential to reduce mortality. Risk factors for PE are well known, but factors associated with delayed diagnosis are less clear...
Adaptive servoventilation versus noninvasive positive pressure ventilation for central, mixed, and complex sleep apnea syndromesTimothy I Morgenthaler
Mayo Clinic Sleep Disorders Center, 200 First Street SW, Rochester, MN 55905, USA
Sleep 30:468-75. 2007....
Practice parameters for behavioral treatment of bedtime problems and night wakings in infants and young childrenTimothy I Morgenthaler
Mayo Sleep Disorders Center, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Sleep 29:1277-81. 2006..Finally, recommendations are provided regarding the beneficial effects of behavioral treatments on secondary outcomes, including daytime functioning (child) and parental well-being...
Treatment of complex sleep apnea syndrome: a retrospective comparative reviewSnigdha S Pusalavidyasagar
Division of Cardiovascular Research, Mayo Clinic, Rochester, USA
Sleep Med 7:474-9. 2006..6 vs. 17.7%) (all P<0.050). CONCLUSION: CompSAS patients have more CPAP interface problems and require more follow-up than OSAS patients but with intervention may have similar treatment results compared to patients with OSAS...
Sonographically guided thoracentesis and rate of pneumothoraxTerrance W Barnes
Division of Pulmonary and Critical Care Medicine, Desk East 18, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA
J Clin Ultrasound 33:442-6. 2005..CONCLUSIONS: The routine use of sonography during diagnostic thoracentesis is associated with a reduced rate of pneumothorax and tube thoracostomy...
Effects of continuous positive airway pressure on stridor in multiple system atrophy-sleep laryngoscopyTomasz J Kuzniar
Sleep Disorders Center, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Clin Sleep Med 5:65-7. 2009..We discuss the possible mechanisms of action of CPAP in MSA-associated stridor...
A patient with obstructive sleep apnea undergoing bariatric surgeryTomasz J Kuzniar
Division of Pulmonary and Critical Care Medicine, Evanston Northwestern Healthcare, Evanston, IL 60201, USA
J Clin Sleep Med 4:279-80. 2008
Diagnostic accuracy of split-night polysomnogramsImran S Khawaja
Center for Sleep Medicine, Mayo Clinic, Rochester, MN 55905, USA
J Clin Sleep Med 6:357-62. 2010..The aim of this study was to determine the diagnostic accuracy of SN-PSG, including at the lower range of AHIs...
Moving beyond empiric continuous positive airway pressure (CPAP) trials for central sleep apnea: a multi-modality titration studyTomasz J Kuzniar
Sleep Disorders Center, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Sleep Breath 11:259-66. 2007..This approach may lead to establishing the diagnosis and treatment plans faster, while reducing unnecessary testing...
Obstructive sleep apnea-hypopnea syndromeEric J Olson
Mayo Clinic College of Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Sleep Disorders Center, 200 1st Street SW, Rochester, MN 55905, USA
Prim Care 32:329-59. 2005..CPAP is the treatment of choice for most patients. Education, follow-up, and heated humidification may help bolster compliance. Lifestyle modifications, oral appliances, and upper surgeries are additional treatment options...
Reducing iatrogenic risk in thoracentesis: establishing best practice via experiential training in a zero-risk environmentDarlene R Duncan
Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
Chest 135:1315-20. 2009..We reviewed our practice model and implemented a unique experiential training paradigm in a zero-risk simulation environment to improve efficacy, timeliness, service orientation, and safety...
Chyloptysis in adults: presentation, recognition, and differential diagnosisKaiser G Lim
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic Foundation, Rocheseter, MN 55905, USA
Chest 125:336-40. 2004..A lymphangiogram is recommended to define the abnormality. In the case of lymphangiectasis, patients respond to either dietary modification and/or ligation of the thoracic duct...
The use of Valeriana officinalis (Valerian) in improving sleep in patients who are undergoing treatment for cancer: a phase III randomized, placebo-controlled, double-blind study (NCCTG Trial, N01C5)Debra L Barton
Mayo Clinic Rochester, Rochester, MN 55905, USA
J Support Oncol 9:24-31. 2011..However, exploratory analyses revealed improvement in some secondary outcomes, such as fatigue. Further research with valerian exploring physiologic effects in oncology symptom management may be warranted...
Low yield of microbiologic studies on pleural fluid specimensTerrance W Barnes
Division of Pulmonary and Critical Care Medicine, Desk East 18, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Chest 127:916-21. 2005..Microbiologic testing of pleural fluid specimens should be ordered more selectively...
Jet lag and other sleep disorders relevant to the travelerR Robert Auger
Center for Sleep Medicine, Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Travel Med Infect Dis 7:60-8. 2009..This condition will be the primary focus of this review, with an emphasis on predisposing factors, preventative options, and treatment strategies...
Effect of shifting costs to patients on specialty evaluation for sleep disordersJoseph G Parambil
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Mayo Clin Proc 81:185-9. 2006..Total utilization did not decrease...
Obstructive lingual thyroid causing sleep apnea: a case report and review of the literatureTerrance W Barnes
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Desk East 18, Mayo Clinic, 200 1st St SW, Rochester, MN 55905, USA
Sleep Med 5:605-7. 2004..OSA caused by lingual thyroid and other oropharyngeal/parapharyngeal tumors are discussed. A careful oropharyngeal examination is important in evaluating patients with complaints of OSA...
Chronic cough from the patient's perspectiveTomasz J Kuzniar
Sleep Disorders Center, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 82:56-60. 2007..To identify the factors that patients consider most concerning about their cough...
The scoring of cardiac events during sleepSean M Caples
Mayo Clinic College of Medicine, Rochester, MN, USA
J Clin Sleep Med 3:147-54. 2007..In the future, expansion to multiple ECG leads and the use of alternative tools may provide better definition of heart rates and cardiac events during sleep...
Obstructive sleep apnea-hypopnea syndromeEric J Olson
Sleep Disorders Center, Division of Pulmonary and Critical Care Medicine and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
Mayo Clin Proc 78:1545-52. 2003..It discusses complications, clinical recognition, the polysomnographic report, and treatment of OSAHS, including strategies for troubleshooting problems associated with continuous positive airway pressure therapy...
Treatment of obstructive sleep apnea is associated with decreased cardiac death after percutaneous coronary interventionAndrew Cassar
Department of Internal Medicine, Mayo College of Medicine, Rochester, Minnesota 55902, USA
J Am Coll Cardiol 50:1310-4. 2007..Our purpose was to compare outcomes of patients treated for obstructive sleep apnea (OSA) versus patients with untreated OSA, all of whom had undergone percutaneous coronary intervention (PCI)...
Use of ambulatory overnight oximetry to investigate sleep apnea in a general internal medicine practiceMatthew W Martinez
Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 80:455-62. 2005..Rather, severity of oximetry abnormalities is used along with other patient-related factors and sleep study accessibility to prioritize the need and urgency of further evaluation...
Practice parameters for the medical therapy of obstructive sleep apneaTimothy I Morgenthaler
Sleep Disorders Center, Pulm Crit Care Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Sleep 29:1031-5. 2006..Positional therapy, or methods for preventing sleep in the supine position, has probably been underutilized due to lack of easily measured predictive factors and randomized controlled trials...
A clinical deterioration prediction tool for internal medicine patientsLisa L Kirkland
Mayo Clinic Rochester, 200 First Street SW, Rochester, MN 55905, USA
Am J Med Qual 28:135-42. 2013..This tool created using routinely collected clinical measurements can serve as a very early warning system for hospitalized medical patients...
Zolpidem is independently associated with increased risk of inpatient fallsBhanu Prakash Kolla
Center for Sleep Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
J Hosp Med 8:1-6. 2013..Yet, it is a commonly used hypnotic agent in the inpatient setting. Zolpidem use in hospitalized patients may be a significant and potentially modifiable risk factor for falling...
Adaptive servoventilation in patients with central or complex sleep apnea related to chronic opioid use and congestive heart failureKannan Ramar
Center for Sleep Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
J Clin Sleep Med 8:569-76. 2012..Both CompSAS and CSA may occur in the setting of CHF and with the use of chronic opioids. We hypothesized that ASV would be less successful in treatment of CSA and CompSAS secondary to opioid use than in CHF patients...
Bronchoesophageal fistula due to broncholithiasis: a case seriesMonique A P Ford
Division of General Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
Respir Med 99:830-5. 2005..The diagnosis is usually established by radiocontrast studies of the esophagus or incidentally during operations. Surgical repair is required...
Measuring faculty reflection on adverse patient events: development and initial validation of a case-based learning systemChristopher M Wittich
Department of Internal Medicine, Division of General Internal Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
J Gen Intern Med 26:293-8. 2011..Critical reflection by faculty physicians on adverse patient events is important for changing physician's behaviors. However, there is little research regarding physician reflection on quality improvement (QI)...
Practice parameters for the treatment of snoring and Obstructive Sleep Apnea with oral appliances: an update for 2005Clete A Kushida
Stanford University Center of Excellence for Sleep Disorders, CA, USA
Sleep 29:240-3. 2006..Regular follow up is also needed to assess the patient for signs and symptoms of worsening OSA. Research to define patient characteristics more clearly for OA acceptance, success, and adherence is needed...
Practice parameters for the use of continuous and bilevel positive airway pressure devices to treat adult patients with sleep-related breathing disordersClete A Kushida
Stanford University Center of Excellence for Sleep Disorders, Stanford, CA, USA
Sleep 29:375-80. 2006..9) CPAP and BPAP therapy are safe; side effects and adverse events are mainly minor and reversible. 10) BPAP may be useful in treating some forms of restrictive lung disease or hypoventilation syndromes associated with hypercapnia...
Natural course of complex sleep apnea--a retrospective studyTomasz J Kuzniar
Division of Pulmonary and Critical Care, Evanston Northwestern Healthcare, Evanston, IL, USA
Sleep Breath 12:135-9. 2008..A prospective trial is merited to determine the optimal treatment for these patients...
