Research Topics
Species | Steven M MillerSummaryAffiliation: Mayo Clinic Country: USA Publications
| Collaborators
|
Detail Information
Publications
Haem oxygenase in enteric nervous system of human stomach and jejunum and co-localization with nitric oxide synthaseS M Miller
Department of Physiology and Biophysics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
Neurogastroenterol Motil 13:121-31. 2001....- Circumferential, not longitudinal, colonic stretch increases synaptic input to mouse prevertebral ganglion neuronsSteven M Miller
Department of Physiology and Biophysics, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Physiol Gastrointest Liver Physiol 285:G1129-38. 2003..These results suggest that colonic mechanosensory afferent nerves projecting to the SMG function as length or stretch detectors in parallel to the circular muscle layer... - Relationship between colonic motility and cholinergic mechanosensory afferent synaptic input to mouse superior mesenteric ganglionS M Miller
Department of Physiology and Biophysics, and Division of Gastroenterology and Hepatology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
Neurogastroenterol Motil 14:339-48. 2002..Most had short, club-like dendritic processes and appeared uni-axonal. These results show that mechanosensory intestinofugal afferent nerves monitor intracolonic volume changes... - Carbon monoxide activates human intestinal smooth muscle L-type Ca2+ channels through a nitric oxide-dependent mechanismInja Lim
Enteric Neuroscience Program, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Am J Physiol Gastrointest Liver Physiol 288:G7-14. 2005..CO-induced NO production may explain the apparent discrepancy between the low affinity of guanylyl cyclase for CO and the robust cGMP production evoked by CO... - alpha(1C) (Ca(V)1.2) L-type calcium channel mediates mechanosensitive calcium regulationGreg L Lyford
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Physiol Cell Physiol 283:C1001-8. 2002..These data demonstrate mechanical regulation of calcium entry through molecularly identified L-type calcium channels in mammalian cells and suggest that the mechanosensitivity resides within the pore forming alpha(1C)-subunit... - Cytoskeletal modulation of sodium current in human jejunal circular smooth muscle cellsPeter R Strege
Department of Physiology and Biophysics, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
Am J Physiol Cell Physiol 284:C60-6. 2003..In conclusion, the Na(+) current expressed in human jejunal circular smooth muscle cells appears to be regulated by the cytoskeleton. An intact actin cytoskeleton is required for perfusion-induced activation of the Na(+) current... - Syntrophin gamma 2 regulates SCN5A gating by a PDZ domain-mediated interactionYijun Ou
Enteric Neuroscience Program, Department of Physiology and Biophysics and Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
J Biol Chem 278:1915-23. 2003.... 
PACAP modulation of the colon-inferior mesenteric ganglion reflex in the guinea pigLeonid G Ermilov
Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
J Physiol 560:231-47. 2004..These results suggest involvement of a PACAP-ergic pathway, operated through PAC1-Rs, in controlling the colon-IMG reflex...- Local presentation of Steel factor increases expression of c-kit immunoreactive interstitial cells of Cajal in cultureAdam Rich
Enteric Neuroscience Program, Department of Physiology and Biophysics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
Am J Physiol Gastrointest Liver Physiol 284:G313-20. 2003..These results are consistent with the hypothesis that the membrane-bound form of SF preferentially contributes to expression of c-kit-positive ICC under cell culture conditions... - Morphology and electrophysiology of neurons in dog paraventricular nucleus: in vitro studyLei Sha
Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Brain Res 1010:95-107. 2004..In summary, the brain slice technique was used to study the morphology and electrophysiology of single neurons of the dog brain. Electrophysiological and morphological properties of the three neuron groups were identified and discussed... - A major role for carbon monoxide as an endogenous hyperpolarizing factor in the gastrointestinal tractGianrico Farrugia
Enteric Neuroscience Program, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Proc Natl Acad Sci U S A 100:8567-70. 2003..Our results suggest that CO is a critical hyperpolarizing factor required for the maintenance of intestinal smooth muscle membrane potential and gradient... - Role of extrinsic innervation in modulating nitrergic transmission in the canine ileocolonic regionSomchai Leelakusolvong
Division of Gastroenterology and Hepatology, Gastroenterology Research Unit and Enteric Neurosciences Program, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Physiol Gastrointest Liver Physiol 283:G230-9. 2002..Nonnitrergic extrinsic nerve pathways mediate reflex colonic relaxation during ileal distension. Enteric isolation augments the number of NOS fibers, an effect not modified by extrinsic denervation... - Paraneoplastic dysmotility: loss of interstitial cells of CajalDarrell S Pardi
Department of Physiology and Biophysics, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Gastroenterol 97:1828-33. 2002..The histopathology of this case suggests that interstitial cells of Cajal may be a target in the pathogenesis of paraneoplastic motility disorders... - Sodium current in human jejunal circular smooth muscle cellsAdrian N Holm
Department of Physiology and Biophysics, Enteric Neuroscience Program, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
Gastroenterology 122:178-87. 2002..CONCLUSIONS: Human jejunal circular smooth muscle cells express a tetrodotoxin-insensitive Na(+) channel, probably SCN5A. Whether SCN5A plays a role in the pathophysiology of human gut dysmotilities remains to be determined... - Optimizing conditions and avoiding pitfalls for prolonged axonal tracing with carbocyanine dyes in fixed rat spinal cordsBingkun K Chen
Neuroscience Research Program and Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Neurosci Methods 154:256-63. 2006..Our data suggested that higher temperature facilitated dye diffusion along the axons, and demonstrated that with caution DiI and DiO could be used as specific tracers in the same spinal cords... - Modulation of calcium signaling by interleukin-13 in human airway smooth muscle: role of CD38/cyclic adenosine diphosphate ribose pathwayDeepak A Deshpande
Department of Veterinary Pathobiology, University of Minnesota, St Paul, MN, USA
Am J Respir Cell Mol Biol 31:36-42. 2004..These findings indicate that the CD38/cADPR-dependent pathway has a major role in IL-13-induced modulation of calcium signaling in human ASM... - Chronic intestinal pseudoobstruction associated with altered interstitial cells of cajal networksAriel E Feldstein
Division of Gastroenterology and Hepatology, Department of Pediatrics, Mayo Medical School, Mayo Foundation and Clinic, 200 First Street SW, Rochester, MN 55905, U.S.A
J Pediatr Gastroenterol Nutr 36:492-7. 2003 - The use of tDCS and CVS as methods of non-invasive brain stimulationGregory Been
Alfred Psychiatry Research Centre, The Alfred Hospital and Monash University School of Psychology, Psychiatry and Psychological Medicine, Commercial Rd, Melbourne, VIC 3004, Australia
Brain Res Rev 56:346-61. 2007..Importantly, they are both inexpensive relative to other brain stimulation techniques such as electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS)...