Alexander Meves

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. doi request reprint Tumor Cell Adhesion As a Risk Factor for Sentinel Lymph Node Metastasis in Primary Cutaneous Melanoma
    Alexander Meves
    Alexander Meves, Ekaterina Nikolova, Joel B Heim, Edwin J Squirewell, Clark C Otley, Louis A Schenck, Amy L Weaver, and Vera J Suman, Mayo Clinic, Rochester, MN Mark A Cappel, Mayo Clinic, Jacksonville, FL Mark R Pittelkow, Mayo Clinic, Scottsdale, AZ and Nille Behrendt, Ditte M Saunte, and Jorgen Lock Andersen, Hospital Roskilde, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
    J Clin Oncol 33:2509-15. 2015
  2. ncbi request reprint Does ultraviolet radiation affect vaccination efficacy?
    Alexander Meves
    Department of Dermatology, Mayo Clinic, Rochester MN 55905, USA
    Int J Dermatol 45:1019-24. 2006
  3. doi request reprint The Kindlin protein family: new members to the club of focal adhesion proteins
    Alexander Meves
    Department of Molecular Medicine, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany
    Trends Cell Biol 19:504-13. 2009
  4. pmc β1 integrins with individually disrupted cytoplasmic NPxY motifs are embryonic lethal but partially active in the epidermis
    Alexander Meves
    Department of Dermatology, Mayo Clinic, Rochester, Minnesota, USA
    J Invest Dermatol 133:2722-31. 2013
  5. ncbi request reprint Antipsoriatic drug anthralin induces EGF receptor phosphorylation in keratinocytes: requirement for H(2)O(2) generation
    Dominik Peus
    Department of Dermatology and Biochemistry, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    Exp Dermatol 13:78-85. 2004
  6. doi request reprint In vivo SILAC-based proteomics reveals phosphoproteome changes during mouse skin carcinogenesis
    Sara Zanivan
    Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany
    Cell Rep 3:552-66. 2013
  7. pmc Beta1 integrin cytoplasmic tyrosines promote skin tumorigenesis independent of their phosphorylation
    Alexander Meves
    Department of Molecular Medicine, Max Planck Institute for Biochemistry, 82152 Martinsried, Germany
    Proc Natl Acad Sci U S A 108:15213-8. 2011
  8. doi request reprint Sorting nexin 31 binds multiple β integrin cytoplasmic domains and regulates β1 integrin surface levels and stability
    Hui Yuan Tseng
    Department of Molecular Medicine, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany
    J Mol Biol 426:3180-94. 2014
  9. doi request reprint Sorting nexin 17 prevents lysosomal degradation of β1 integrins by binding to the β1-integrin tail
    Ralph Thomas Böttcher
    Department of Molecular Medicine, Max Planck Institute for Biochemistry, 82152 Martinsried, Germany
    Nat Cell Biol 14:584-92. 2012
  10. doi request reprint Staphylococcal scalded skin syndrome and toxic shock syndrome after tooth extraction
    Jerry D Brewer
    Department of Dermatology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Am Acad Dermatol 59:342-6. 2008

Collaborators

Detail Information

Publications15

  1. doi request reprint Tumor Cell Adhesion As a Risk Factor for Sentinel Lymph Node Metastasis in Primary Cutaneous Melanoma
    Alexander Meves
    Alexander Meves, Ekaterina Nikolova, Joel B Heim, Edwin J Squirewell, Clark C Otley, Louis A Schenck, Amy L Weaver, and Vera J Suman, Mayo Clinic, Rochester, MN Mark A Cappel, Mayo Clinic, Jacksonville, FL Mark R Pittelkow, Mayo Clinic, Scottsdale, AZ and Nille Behrendt, Ditte M Saunte, and Jorgen Lock Andersen, Hospital Roskilde, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
    J Clin Oncol 33:2509-15. 2015
    ..We present a multi-institutional study to discover new molecular risk factors associated with SLN positivity in thin and intermediate-thickness melanoma...
  2. ncbi request reprint Does ultraviolet radiation affect vaccination efficacy?
    Alexander Meves
    Department of Dermatology, Mayo Clinic, Rochester MN 55905, USA
    Int J Dermatol 45:1019-24. 2006
  3. doi request reprint The Kindlin protein family: new members to the club of focal adhesion proteins
    Alexander Meves
    Department of Molecular Medicine, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany
    Trends Cell Biol 19:504-13. 2009
    ....
  4. pmc β1 integrins with individually disrupted cytoplasmic NPxY motifs are embryonic lethal but partially active in the epidermis
    Alexander Meves
    Department of Dermatology, Mayo Clinic, Rochester, Minnesota, USA
    J Invest Dermatol 133:2722-31. 2013
    ....
  5. ncbi request reprint Antipsoriatic drug anthralin induces EGF receptor phosphorylation in keratinocytes: requirement for H(2)O(2) generation
    Dominik Peus
    Department of Dermatology and Biochemistry, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    Exp Dermatol 13:78-85. 2004
    ..Our data identify anthralin-induced reactive oxygen species and, more specifically, H(2)O(2) as an important upstream mediator required for ligand-independent epidermal growth factor receptor phosphorylation and downstream signaling...
  6. doi request reprint In vivo SILAC-based proteomics reveals phosphoproteome changes during mouse skin carcinogenesis
    Sara Zanivan
    Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany
    Cell Rep 3:552-66. 2013
    ..This detailed molecular picture, both at the proteome and phosphoproteome level, will prove useful for the study of mechanisms of tumor progression...
  7. pmc Beta1 integrin cytoplasmic tyrosines promote skin tumorigenesis independent of their phosphorylation
    Alexander Meves
    Department of Molecular Medicine, Max Planck Institute for Biochemistry, 82152 Martinsried, Germany
    Proc Natl Acad Sci U S A 108:15213-8. 2011
    ..We conclude that a Src/FAK signaling unit inhibits differentiation to promote tumorigenesis downstream of β1 integrin and independent of β1 integrin tyrosine phosphorylation...
  8. doi request reprint Sorting nexin 31 binds multiple β integrin cytoplasmic domains and regulates β1 integrin surface levels and stability
    Hui Yuan Tseng
    Department of Molecular Medicine, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany
    J Mol Biol 426:3180-94. 2014
    ..Altogether, these results demonstrate that SNX31 is an endosomal regulator of β integrins with a restricted expression pattern. ..
  9. doi request reprint Sorting nexin 17 prevents lysosomal degradation of β1 integrins by binding to the β1-integrin tail
    Ralph Thomas Böttcher
    Department of Molecular Medicine, Max Planck Institute for Biochemistry, 82152 Martinsried, Germany
    Nat Cell Biol 14:584-92. 2012
    ..Our results identify SNX17 as a β1-integrin-tail-binding protein that interacts with the free Kindlin-binding site in endosomes to stabilize β1 integrins, resulting in their recycling to the cell surface where they can be reused...
  10. doi request reprint Staphylococcal scalded skin syndrome and toxic shock syndrome after tooth extraction
    Jerry D Brewer
    Department of Dermatology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Am Acad Dermatol 59:342-6. 2008
    ..For patients with acute, exfoliative, generalized erythroderma, TSS and SSSS should be considered. Although rare, it is possible to see both syndromes present concurrently...
  11. doi request reprint Cocaine abuse: dermatologic manifestations and therapeutic approaches
    Jerry D Brewer
    Department of Dermatology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Am Acad Dermatol 59:483-7. 2008
    ....
  12. ncbi request reprint Vitamin C derivative ascorbyl palmitate promotes ultraviolet-B-induced lipid peroxidation and cytotoxicity in keratinocytes
    Alexander Meves
    Department of Dermatology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Invest Dermatol 119:1103-8. 2002
    ..Our data suggest that, despite its antioxidant properties, ascorbic acid-6-palmitate may intensify skin damage following physiologic doses of ultraviolet radiation...
  13. ncbi request reprint Acute graft-versus-host disease after liver transplantation diagnosed by fluorescent in situ hybridization testing of skin biopsy specimens
    Alexander Meves
    Department of Dermatology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Am Acad Dermatol 55:642-6. 2006
    ..We conclude that early testing of skin biopsy specimens using fluorescent in situ hybridization in sex-mismatched patients with orthotopic liver transplantation can serve as an early diagnostic tool for graft-versus-host disease...
  14. ncbi request reprint Promoting safe and effective sun protection strategies
    Alexander Meves
    J Am Acad Dermatol 49:1203-4. 2003
  15. ncbi request reprint Global Solar UV Index: a physician's tool for fighting the skin cancer epidemic
    Alexander Meves
    Radiation and Environmental Health Unit, World Health Organization, Geneva, Switzerland
    Int J Dermatol 42:846-9. 2003