Thomas R Meier

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. doi request reprint Prophylactic P-selectin inhibition with PSI-421 promotes resolution of venous thrombosis without anticoagulation
    Thomas R Meier
    Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Thromb Haemost 99:343-51. 2008
  2. pmc Quantification, distribution, and possible source of bacterial biofilm in mouse automated watering systems
    Thomas R Meier
    Unit for Laboratory Animal Medicine, Medical School, University of Michigan, Ann Arbor, MI, USA
    J Am Assoc Lab Anim Sci 47:63-70. 2008
  3. ncbi request reprint Resolution of venous thrombosis using a novel oral small-molecule inhibitor of P-selectin (PSI-697) without anticoagulation
    Daniel D Myers
    Jobst Vascular Research Laboratories, Section of Vascular Surgery, 2Unit for Laboratory Animal Medicine and 3Department of Radiology, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0654, USA
    Thromb Haemost 97:400-7. 2007
  4. ncbi request reprint Treatment with an oral small molecule inhibitor of P selectin (PSI-697) decreases vein wall injury in a rat stenosis model of venous thrombosis
    Daniel D Myers
    Jobst Vascular Research Laboratories, Section of Vascular Surgery, University of Michigan Medical Center, Ann Arbor, 48109 0654, USA
    J Vasc Surg 44:625-32. 2006
  5. doi request reprint Dose-dependent thrombus resolution due to oral plaminogen activator inhibitor (PAI)-1 inhibition with tiplaxtinin in a rat stenosis model of venous thrombosis
    Sanjiv Baxi
    Jobst Vascular Research Laboratories, Section of Vascular Surgery, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0654, USA
    Thromb Haemost 99:749-58. 2008
  6. ncbi request reprint Gangrenous Clostridium perfringens infection and subsequent wound management in a rhesus macaque (Macaca mulatta)
    Thomas R Meier
    Unit for Laboratory Animal Medicine, Jobst Vascular Research Laboratories, University of Michigan Medical Center, Ann Arbor, MI, USA
    J Am Assoc Lab Anim Sci 46:68-73. 2007

Collaborators

Detail Information

Publications6

  1. doi request reprint Prophylactic P-selectin inhibition with PSI-421 promotes resolution of venous thrombosis without anticoagulation
    Thomas R Meier
    Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Thromb Haemost 99:343-51. 2008
    ..This study is the first to demonstrate a reduction in MPTFA associated with vein reopening and reduced vein inflammation due to oral P-selectin inhibition in a baboon model of DVT...
  2. pmc Quantification, distribution, and possible source of bacterial biofilm in mouse automated watering systems
    Thomas R Meier
    Unit for Laboratory Animal Medicine, Medical School, University of Michigan, Ann Arbor, MI, USA
    J Am Assoc Lab Anim Sci 47:63-70. 2008
    ..Bacterial biofilm distribution was not significantly different across location quartiles of the rack manifold, but bacterial levels differed between the shelf pipe and connecting elbow pipes...
  3. ncbi request reprint Resolution of venous thrombosis using a novel oral small-molecule inhibitor of P-selectin (PSI-697) without anticoagulation
    Daniel D Myers
    Jobst Vascular Research Laboratories, Section of Vascular Surgery, 2Unit for Laboratory Animal Medicine and 3Department of Radiology, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0654, USA
    Thromb Haemost 97:400-7. 2007
    ..01). This study is the first to demonstrate the effectiveness of oral P-selectin inhibition to modify venous thrombogenesis, increase vein lumen opening, and decrease inflammation in a large animal model...
  4. ncbi request reprint Treatment with an oral small molecule inhibitor of P selectin (PSI-697) decreases vein wall injury in a rat stenosis model of venous thrombosis
    Daniel D Myers
    Jobst Vascular Research Laboratories, Section of Vascular Surgery, University of Michigan Medical Center, Ann Arbor, 48109 0654, USA
    J Vasc Surg 44:625-32. 2006
    ....
  5. doi request reprint Dose-dependent thrombus resolution due to oral plaminogen activator inhibitor (PAI)-1 inhibition with tiplaxtinin in a rat stenosis model of venous thrombosis
    Sanjiv Baxi
    Jobst Vascular Research Laboratories, Section of Vascular Surgery, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0654, USA
    Thromb Haemost 99:749-58. 2008
    ..05). This is the first study to demonstrate dose related effects of PAI-039 on increasing thrombus resolution and inferior vena cava blood flow without adverse effects on anti-coagulation in a rat stenosis model of venous thrombosis...
  6. ncbi request reprint Gangrenous Clostridium perfringens infection and subsequent wound management in a rhesus macaque (Macaca mulatta)
    Thomas R Meier
    Unit for Laboratory Animal Medicine, Jobst Vascular Research Laboratories, University of Michigan Medical Center, Ann Arbor, MI, USA
    J Am Assoc Lab Anim Sci 46:68-73. 2007
    ..This case study is the first report of Clostridium perfringens myonecrosis in a laboratory nonhuman primate. We discuss various methodologies for the diagnosis and treatment of necrotizing clostridial infections...