Research Topics
| C L LeibsonSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Venous thromboembolism in nursing home residents: role of selected risk factorsCynthia L Leibson
Divisions of Epidemiology, Department of Health Sciences Research, Mayo Clinic Rochester, Rochester, Minnesota 55905, USA
J Am Geriatr Soc 60:1718-23. 2012..To provide nursing home (NH)-specific estimates to assess whether venous thromboembolism (VTE) risk factors identified for the general population apply to NH residents...
Medical care costs associated with traumatic brain injury over the full spectrum of disease: a controlled population-based studyCynthia L Leibson
Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, 200 First Street, S W Rochester, MN 55905, USA
J Neurotrauma 29:2038-49. 2012..Preventing probable and possible events might facilitate substantial reductions in TBI-associated medical care costs...
Incidence and characterization of diagnosed endometriosis in a geographically defined populationCynthia L Leibson
Health Sciences Research, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
Fertil Steril 82:314-21. 2004..We examined whether widespread use of laparoscopy was accompanied by increased diagnosis of asymptomatic endometriosis, inflated rates of diagnosis, or changes in the clinical spectrum of disease...
Peripheral arterial disease, diabetes, and mortalityCynthia L Leibson
Department of Health Sciences Research, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Diabetes Care 27:2843-9. 2004....
Risk factors for venous thromboembolism in nursing home residentsCynthia L Liebson
Department of Health Sciences Research, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Mayo Clin Proc 83:151-7. 2008..To determine risk factors for venous thromboembolism (VTE) among nursing home (NH) residents...
Identifying in-hospital venous thromboembolism (VTE): a comparison of claims-based approaches with the Rochester Epidemiology Project VTE cohortCynthia L Leibson
Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester 55905, Minnesota, USA
Med Care 46:127-32. 2008..We estimated sensitivity, specificity, PPV, and negative predictive value (NPV) of claims-based approaches using the Rochester Epidemiology Project (REP) venous thromboembolism (VTE) cohort as a "gold standard."..
Direct medical costs associated with Parkinson's disease: a population-based studyCynthia L Leibson
Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Mov Disord 21:1864-71. 2006..99, for those with tremor). These population-based estimates of PD-associated direct medical costs from onset forward can uniquely inform policy decisions and cost-effectiveness research...
Comorbid conditions associated with Parkinson's disease: a population-based studyCynthia L Leibson
Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Mov Disord 21:446-55. 2006..quot; The excess morbidity and mortality observed for persons with PD are consistent with recognized PD sequelae...
Relative risk of mortality associated with diabetes as a function of birth weightCynthia L Leibson
Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Diabetes Care 28:2839-43. 2005..Birth weight is a risk factor for both diabetes and mortality. Diabetes is a risk factor for mortality. Whether the excess mortality observed for diabetes varies with birth weight is unclear...
Emergency department use and costs for youth with attention-deficit/hyperactivity disorder: associations with stimulant treatmentCynthia L Leibson
Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Ambul Pediatr 6:45-53. 2006..To investigate whether, among youth with attention-deficit/hyperactivity disorder (ADHD), stimulant treatment is associated with reduced emergency department (ED) use and medical costs...
Economic implications of attention-deficit hyperactivity disorder for healthcare systemsCynthia L Leibson
Department of Health Sciences Research, Mayo Clinic Foundation, Rochester, Minnesota 55905, USA
Pharmacoeconomics 21:1239-62. 2003....
Mortality, disability, and nursing home use for persons with and without hip fracture: a population-based studyCynthia L Leibson
Department of Health Sciences Research, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
J Am Geriatr Soc 50:1644-50. 2002..To compare persons with and without hip fracture for subsequent mortality and change in disability and nursing home (NH) use...
Use and costs of medical care for children and adolescents with and without attention-deficit/hyperactivity disorderC L Leibson
Department of Helth Sciences Research, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
JAMA 285:60-6. 2001..A shortage of data exists on medical care use by persons with attention-deficit/hyperactivity disorder (ADHD)...
The role of depression in the association between self-rated physical health and clinically defined illnessC L Leibson
Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
Gerontologist 39:291-8. 1999..Also, a diagnosis of minor depression should not forestall investigation of inconsistencies between patient report and clinical evidence...
Temporal trends in BMI among adults with diabetesC L Leibson
Department of Health Sciences Research, Mayo Clinic Foundation, 200 First St SW, Rochester, MN 55905, USA
Diabetes Care 24:1584-9. 2001..Increasing obesity within the general population has been accompanied by rising rates of diabetes. The extent to which obesity has increased among people with diabetes is unknown, as are the potential consequences for diabetes outcomes...
Trends in persistent proteinuria in adult-onset diabetes: a population-based studyT S Larson
Division of Nephrology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
Diabetes Care 23:51-6. 2000..This study investigates temporal trends in the prevalence and incidence of persistent proteinuria among people with adult-onset diabetes (age > or =40 years)...
Is diabetes mellitus an independent risk factor for venous thromboembolism?: a population-based case-control studyJohn A Heit
Division of Cardiovascular Diseases, Section of Vascular Diseases, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Arterioscler Thromb Vasc Biol 29:1399-405. 2009..Consequently, we tested diabetes for an independent association with incident VTE...
Relative risk of mortality after traumatic brain injury: a population-based study of the role of age and injury severityJulie Testa Flaada
Department of Psychiatry, Mayo Clinic, Rochester, Minnesota 55905, USA
J Neurotrauma 24:435-45. 2007..Findings have implications for (1) reducing the number of excess deaths following TBI and (2) caring for survivors...
Fracture risk after the diagnosis of Parkinson's disease: Influence of concomitant dementiaL Joseph Melton
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Mov Disord 21:1361-7. 2006..1). The increased fracture risk in patients with PD is not entirely explained by concomitant dementia, and additional study is needed to determine the relative contributions to fracture risk of falls versus bone loss in these patients...
Effects of changing diagnostic criteria on the risk of developing diabetesS F Dinneen
Division of Endocrinology and Metabolism, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
Diabetes Care 21:1408-13. 1998..8 mmol/l (the level recommended by the National Diabetes Data Group [NDDG] in 1979) to 7.0 mmol/l. We examined the impact of this change on rates of progression to overt diabetes from different levels of FPG...
Secular trends in hip fracture incidence and recurrenceL J Melton
Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Osteoporos Int 20:687-94. 2009..The decline in hip fracture incidence is now accompanied by a further reduction in the likelihood of a recurrent hip fracture among survivors of the first fracture...
Direct medical costs attributable to osteoporotic fracturesS E Gabriel
Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA
Osteoporos Int 13:323-30. 2002..The use of incremental costs in economic analyses will provide a more accurate reflection of the true cost-effectiveness of osteoporosis prevention...
Diabetes in heart failure: prevalence and impact on outcome in the populationAaron M From
The Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
Am J Med 119:591-9. 2006..DM is associated with a large increase in mortality, particularly among subjects without clinical CAD, underscoring the importance of aggressive management of DM in HF...
Effect of second-generation sulfonylureas on survival in patients with diabetes mellitus after myocardial infarctionAdelaide M Arruda-Olson
Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Mayo Clin Proc 84:28-33. 2009..To examine possible adverse effects of sulfonylureas on survival among patients with diabetes mellitus (DM) who experience a myocardial infarction (MI)...
Renal stone epidemiology in Rochester, Minnesota: an updateJ C Lieske
Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota 55905, USA
Kidney Int 69:760-4. 2006..Therefore, since 1970 overall NL incidence rates in Rochester have remained relatively flat. However, NL rates for men have declined, whereas rates for women appear to be increasing. The reasons remain to be determined...
Long-term fracture risk among women with proven endometriosisL Joseph Melton
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Fertil Steril 86:1576-83. 2006..To determine whether women with pelvic endometriosis are at increased fracture risk...
Diabetes mellitus and the risk of urinary tract stones: a population-based case-control studyJohn C Lieske
Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Am J Kidney Dis 48:897-904. 2006..Because nephrolithiasis has been associated with obesity, an important risk factor for type 2 diabetes mellitus (DM), we tested the hypothesis that DM prevalence is increased in individuals who develop renal stones...
Pancreatic cancer-associated diabetes mellitus: prevalence and temporal association with diagnosis of cancerSuresh T Chari
Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Gastroenterology 134:95-101. 2008..The temporal association between diabetes mellitus and pancreatic cancer is poorly understood. We compared temporal patterns in diabetes prevalence in pancreatic cancer and controls...
The mayo classification system for traumatic brain injury severityJames F Malec
Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, Minnesota 55901, USA
J Neurotrauma 24:1417-24. 2007....
Trends in the mortality burden associated with diabetes mellitus: a population-based study in Rochester, Minn, 1970-1994Randal J Thomas
Department of Medicine, Mayo Clinic and Foundation, 200 First St SW, Rochester, MN 55905, USA
Arch Intern Med 163:445-51. 2003..The prevalence of diabetes mellitus (DM) has increased markedly in recent decades, but trends in the mortality burden associated with DM are unclear. Therefore, we analyzed population-based longitudinal data to address this issue...
A survey of very-long-term outcomes after traumatic brain injury among members of a population-based incident cohortAllen W Brown
Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, Minnesota 55905, USA
J Neurotrauma 28:167-76. 2011..These findings highlight the importance of providing coordinated medical rehabilitation and community-based support services to promote positive outcomes over the life span after TBI...
A bone structural basis for fracture risk in diabetesL Joseph Melton
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, 200 First Street Southwest, Rochester, Minnesota 55905, USA
J Clin Endocrinol Metab 93:4804-9. 2008..Elevated areal bone mineral density (aBMD) in type 2 diabetes mellitus is inconsistent with increased fracture risk at some skeletal sites...
Fracture risk in type 2 diabetes: update of a population-based studyL Joseph Melton
Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, Minnesota, USA
J Bone Miner Res 23:1334-42. 2008....
Temporal association of changes in fasting blood glucose and body mass index with diagnosis of pancreatic cancerRahul Pannala
Department of Gastroenterology and Hepatology, Fiterman Center for Digestive Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Gastroenterol 104:2318-25. 2009..Although the association between diabetes mellitus (DM) and pancreatic cancer is well described, temporal patterns of changes in fasting blood glucose (FBG) and body mass index (BMI) before pancreatic cancer diagnosis are not known...
Temporal trends in prevalence of diabetes mellitus in a population-based cohort of incident myocardial infarction and impact of diabetes on survivalGunjan Y Gandhi
Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
Mayo Clin Proc 81:1034-40. 2006..To determine the temporal trends in prevalence of confirmed diabetes mellitus (DM), time from the date DM criteria were met to myocardial infarction (MI), and impact of DM on survival...
Case definition in epidemiologic studies of AD/HDSlavica K Katusic
Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Ann Epidemiol 15:430-7. 2005..Propose a five-step multigating, multimodal procedure for research case definition and identification of attention-deficit/hyperactivity disorder (AD/HD) in population-based epidemiologic studies...
Probability of pancreatic cancer following diabetes: a population-based studySuresh T Chari
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Rochester, Minnesota 55905, USA
Gastroenterology 129:504-11. 2005..Although diabetes occurs frequently in pancreatic cancer, the value of new-onset diabetes as a marker of underlying pancreatic cancer is unknown...
Psychostimulant treatment and risk for substance abuse among young adults with a history of attention-deficit/hyperactivity disorder: a population-based, birth cohort studySlavica K Katusic
Department of Health Sciences Research, Division of Clinical Epidemiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
J Child Adolesc Psychopharmacol 15:764-76. 2005..The aim of this study was to evaluate the association between stimulant treatment and the risk for substance abuse among young adults with a childhood diagnosis of attention- deficit/hyperactivity disorder (ADHD)...
Development and validation of a screen for specialized discharge planning servicesDiane E Holland
Division of Nursing Research, Department of Nursing, Mayo Clinic, Rochester, MN 55902, USA
Nurs Res 55:62-71. 2006..There is no rigorously developed and empirically validated screening tool to identify, early in the hospital stay, those adults who will use specialized hospital discharge planning services...
Long-term stimulant medication treatment of attention-deficit/hyperactivity disorder: results from a population-based studyWilliam J Barbaresi
Department of Pediatric and Adolescent Medicine, Division of Developmental and Behavioral Pediatrics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Dev Behav Pediatr 27:1-10. 2006..These results demonstrate that the effectiveness of stimulant medication treatment of ADHD provided throughout childhood is comparable to the efficacy of stimulant treatment demonstrated in clinical trials...
Long-term survival after traumatic brain injury: a population-based analysisAllen W Brown
Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN 55905, USA
NeuroRehabilitation 19:37-43. 2004..The case fatality rate for persons with moderate to severe TBI is very high, but among six-month survivors, long-term survival is similar to that for persons with mild TBI...
Impact of case ascertainment on recent trends in diabetes incidence in Rochester, MinnesotaJames P Burke
Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
Am J Epidemiol 155:859-65. 2002..181) from 1987 to 1994, while the incidence of diabetes increased (p = 0.033). Thus, the authors conclude that the increase in diabetes incidence accelerated over the last quinquennium and was not due to increased surveillance...
Predictors of blood pressure control in patients with diabetes and hypertension seen in primary care clinicsMurali K Duggirala
Divison of General Internal Medicine, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Hypertens 18:833-8. 2005..This study was designed to identify predictors of BP control in patients with both diabetes and hypertension who are seen in primary care clinics...
Association of birth weight and type 2 diabetes in Rochester, MinnesotaJames P Burke
Department of Health Sciences Research, Harwick 6, Mayo Clinic, 200 First St, SW, Rochester, MN 55905, USA
Diabetes Care 27:2512-3. 2004
Use of nursing home after stroke and dependence on stroke severity: a population-based analysisR D Brown
Division of Cerebrovascular Diseases, Department of Neurology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA
Stroke 30:924-9. 1999..There are few population-based data available regarding nursing home use after stroke. This study clarifies the use of a nursing home after stroke, as well as its dependence on stroke severity, in a defined population...
Clinically confirmed type 2 diabetes mellitus and colorectal cancer risk: a population-based, retrospective cohort studyPaul J Limburg
Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Am J Gastroenterol 101:1872-9. 2006....
Mortality in amnestic mild cognitive impairment: a prospective community studyA L Hunderfund
Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Neurology 67:1764-8. 2006..CONCLUSIONS: Amnestic mild cognitive impairment is associated with increased mortality, which is greater in multiple-domain aMCI than in single-domain aMCI. Mortality in aMCI subtypes may vary by APOE-epsilon4 allele status...
Referral to autopsy: effect of antemortem cardiovascular disease: a population-based study in Olmsted County, MinnesotaP Targonski
Division of Community Internal Medicine and Geriatrics, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
Ann Epidemiol 11:264-70. 2001....
Left atrial volume: important risk marker of incident atrial fibrillation in 1655 older men and womenT S Tsang
Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Mayo Clin Proc 76:467-75. 2001..CONCLUSION: This study showed that a larger LA volume was associated with a higher risk of AF in older patients. The predictive value of LA volume was incremental to that of clinical risk profile and conventional M-mode LA dimension...
Letter to the editorsAllen W Brown
NeuroRehabilitation 20:67. 2005
Recent trends in the prevalence of coronary disease: a population-based autopsy study of nonnatural deathsPeter N Nemetz
Sauder School of Business, University of British Columbia, Vancouver, British Columbia, Canada
Arch Intern Med 168:264-70. 2008..Despite increases in obesity and diabetes mellitus, mortality caused by coronary disease continues to decline. Recent trends in coronary disease prevalence are unknown...
Trends in cardiovascular complications of diabetesCynthia L Leibson
JAMA 293:1723; author reply 1723. 2005
Coronary atherosclerosis in diabetes mellitus: a population-based autopsy studyTauqir Y Goraya
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic Scottsdale, AZ, USA
J Am Coll Cardiol 40:946-53. 2002....
