T Laskus

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. pmc Uneven distribution of hepatitis C virus quasispecies in tissues from subjects with end-stage liver disease: confounding effect of viral adsorption and mounting evidence for the presence of low-level extrahepatic replication
    T Laskus
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Virol 74:1014-7. 2000
  2. ncbi request reprint Hepatitis C virus in lymphoid cells of patients coinfected with human immunodeficiency virus type 1: evidence of active replication in monocytes/macrophages and lymphocytes
    T Laskus
    Division of Transplantation Medicine, Mayo Clinic, Scottsdale, AZ 85259, USA
    J Infect Dis 181:442-8. 2000
  3. pmc Exposure of hepatitis C virus (HCV) RNA-positive recipients to HCV RNA-positive blood donors results in rapid predominance of a single donor strain and exclusion and/or suppression of the recipient strain
    T Laskus
    Division of Transplantation Medicine, Mayo Clinic Scottsdale, Scottsdale, Arizona 85259, USA
    J Virol 75:2059-66. 2001
  4. ncbi request reprint Exposure of hepatitis C virus-negative recipients to > or =2 infected blood donors
    T Laskus
    Division of Transplantation Medicine, SC Johnson Bldg Sj3, Mayo Clinic Scottsdale, Scottsdale, AZ 85259, USA
    J Infect Dis 183:666-9. 2001
  5. ncbi request reprint Changes in hepatitis C virus population in serum and peripheral blood mononuclear cells in chronically infected patients receiving liver graft from infected donors
    M Radkowski
    Department of Medicine, Mayo Clinic Scottsdale, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA
    Transplantation 72:833-8. 2001
  6. ncbi request reprint Outcome of liver transplantation in hepatitis C virus-infected patients who received hepatitis C virus-infected grafts
    H E Vargas
    Division of Gastroenterology and Hepatology, T E Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Gastroenterology 117:149-53. 1999
  7. pmc Detection and sequence analysis of hepatitis B virus integration in peripheral blood mononuclear cells
    T Laskus
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Virol 73:1235-8. 1999
  8. ncbi request reprint Selection of different 5' untranslated region hepatitis C virus variants during post-transfusion and post-transplantation infection
    J F Gallegos-Orozco
    Division of Transplantation Medicine, Mayo Clinic, Scottsdale, AZ 85259, USA
    J Viral Hepat 13:489-98. 2006

Detail Information

Publications8

  1. pmc Uneven distribution of hepatitis C virus quasispecies in tissues from subjects with end-stage liver disease: confounding effect of viral adsorption and mounting evidence for the presence of low-level extrahepatic replication
    T Laskus
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Virol 74:1014-7. 2000
    ..Our results also suggest that PBMCs, and probably various tissues, can selectively adsorb viral subpopulations differing in the E2 region...
  2. ncbi request reprint Hepatitis C virus in lymphoid cells of patients coinfected with human immunodeficiency virus type 1: evidence of active replication in monocytes/macrophages and lymphocytes
    T Laskus
    Division of Transplantation Medicine, Mayo Clinic, Scottsdale, AZ 85259, USA
    J Infect Dis 181:442-8. 2000
    ..These findings imply that, in HIV-infected subjects, HCV may replicate in the same cells as HIV-1, which raises the possibility of direct interactions between these pathogens...
  3. pmc Exposure of hepatitis C virus (HCV) RNA-positive recipients to HCV RNA-positive blood donors results in rapid predominance of a single donor strain and exclusion and/or suppression of the recipient strain
    T Laskus
    Division of Transplantation Medicine, Mayo Clinic Scottsdale, Scottsdale, Arizona 85259, USA
    J Virol 75:2059-66. 2001
    ..The results of the present study suggest the existence of competition among infecting HCV strains which determines the ultimate outcome of multiple HCV exposure...
  4. ncbi request reprint Exposure of hepatitis C virus-negative recipients to > or =2 infected blood donors
    T Laskus
    Division of Transplantation Medicine, SC Johnson Bldg Sj3, Mayo Clinic Scottsdale, Scottsdale, AZ 85259, USA
    J Infect Dis 183:666-9. 2001
    ..These observations are compatible with the presence of competition among infecting HCV strains that results in the dominance of 1 strain and competitive exclusion or suppression of other strains...
  5. ncbi request reprint Changes in hepatitis C virus population in serum and peripheral blood mononuclear cells in chronically infected patients receiving liver graft from infected donors
    M Radkowski
    Department of Medicine, Mayo Clinic Scottsdale, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA
    Transplantation 72:833-8. 2001
    ..The takeover of one strain by another in PBMC- and serum-derived viral populations seemed to be complete and long lasting...
  6. ncbi request reprint Outcome of liver transplantation in hepatitis C virus-infected patients who received hepatitis C virus-infected grafts
    H E Vargas
    Division of Gastroenterology and Hepatology, T E Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Gastroenterology 117:149-53. 1999
    ..The present organ shortage has brought into question the suitability of hepatitis C virus (HCV)-positive grafts. This study reviewed the outcome of such transplantations in our institution...
  7. pmc Detection and sequence analysis of hepatitis B virus integration in peripheral blood mononuclear cells
    T Laskus
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Virol 73:1235-8. 1999
    ..Integrated HBV DNA sequences, with virus-cell junctions located in the cohesive region between direct repeat 1 (DR1) and DR2, were found in 2 of 10 studied patients...
  8. ncbi request reprint Selection of different 5' untranslated region hepatitis C virus variants during post-transfusion and post-transplantation infection
    J F Gallegos-Orozco
    Division of Transplantation Medicine, Mayo Clinic, Scottsdale, AZ 85259, USA
    J Viral Hepat 13:489-98. 2006
    ..Sequence changes in this region could affect translation efficiency and presumably viral replication...