Research Topics
Species | P J KurtinSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Indolent lymphomas of mature B lymphocytesPaul J Kurtin
Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55906, USA
Hematol Oncol Clin North Am 23:769-90. 2009..They are distinguished from one another on clinical, morphological, phenotypic and genetic grounds. This article reviews the essential diagnostic and biologic features of these clinically indolent B cell malignancies...
Pathologic and clinical features of primary pulmonary extranodal marginal zone B-cell lymphoma of MALT typeP J Kurtin
Division of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota, USA
Am J Surg Pathol 25:997-1008. 2001....
Cell-cell interactions in synovitis. Interactions between T cells and B cells in rheumatoid arthritisC M Weyand
Division of Rheumatology, Mayo Clinic, Rochester, Minnesota 55905, USA
Arthritis Res 2:457-63. 2000..B cells have a critical role in lymphoid organogenesis. Their contribution to synovial inflammation extends beyond antibody secretion and includes the activation and regulation of effector T cells...
Recurrent translocations involving the IRF4 oncogene locus in peripheral T-cell lymphomasA L Feldman
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
Leukemia 23:574-80. 2009..Further, due to its involvement in translocations, MUM1/IRF4 protein may play an important biologic role in some PTCLs, and might represent a possible therapeutic target...
Demonstration of distinct antigenic profiles of small B-cell lymphomas by paraffin section immunohistochemistryP J Kurtin
Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
Am J Clin Pathol 112:319-29. 1999..Paraffin section immunohistochemistry on sections of routinely fixed tissue can be used similarly to flow cytometry and frozen section immunohistochemistry when classifying the lymphomas of small B lymphocytes...
A phase I trial of high dose ProMACE-CytaBOM with granulocyte colony stimulating factor for patients with non-Hodgkin's lymphomaT E Witzig
Division of Internal Medicine and Hematology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
Leuk Lymphoma 28:307-14. 1998..This higher dose ProMACECytaBOM regimen can be given to older adult patients in an outpatient setting. Phase III studies would be required to determine if it produces a superior overall survival compared to other regimens...
Hepatosplenic alphabeta T-cell lymphomas: a report of 14 cases and comparison with hepatosplenic gammadelta T-cell lymphomasW R Macon
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Surg Pathol 25:285-96. 2001..This group, along with the previously recognized gammadelta group, should be recognized as phenotypically heterogeneous subtypes of the same disease entity...
Denileukin diftitox in combination with rituximab for previously untreated follicular B-cell non-Hodgkin's lymphomaS M Ansell
Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA
Leukemia 26:1046-52. 2012....
Cutaneous involvement by angioimmunoblastic T-cell lymphoma with remarkable heterogeneous Epstein-Barr virus expressionH A Brown
Department of Dermatology, Mayo Clinic, Rochester, Minnesota, USA
J Cutan Pathol 28:432-8. 2001..To our knowledge, this case is the most extensive and heterogeneous expression of EBV in cutaneous AILD T-NHL to date...
Orbital lymphoma: radiotherapy outcome and complicationsS L Stafford
Division of Radiation Oncology, Mayo Clinic and Mayo Foundation, Rochester, MN, USA
Radiother Oncol 59:139-44. 2001..Late relapse occurs in sites other than the treated orbit, even in patients with early-stage disease. Doses 35 Gy or higher result in significant late complications and are therefore not indicated for patients with low-grade tumors...
Lymphoid neogenesis in rheumatoid synovitisS Takemura
Department of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
J Immunol 167:1072-80. 2001....
Overexpression of Syk tyrosine kinase in peripheral T-cell lymphomasA L Feldman
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
Leukemia 22:1139-43. 2008....
Efficacy of splenectomy for patients with mantle cell non-Hodgkin's lymphomaY Yoong
Division of Internal Medicine and Hematology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
Leuk Lymphoma 42:1235-41. 2001..There is a subset of pts that have prolonged disease stabilization without the requirement for immediate chemotherapy after splenectomy...
Pulmonary marginal zone lymphoma of MALT type as a cause of localised pulmonary amyloidosisJ K Lim
Division of Hematology and Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
J Clin Pathol 54:642-6. 2001..CONCLUSIONS: Pulmonary marginal zone lymphoma may be found in association with localised amyloid deposition and should be considered in the differential diagnosis of localised pulmonary amyloidosis...
The power of the third dimension: tissue architecture and autoimmunity in rheumatoid arthritisC M Weyand
Departments of Medicine and Immunology, Mayo Clinic Rochester, Rochester, Minnesota 55905, USA
Curr Opin Rheumatol 15:259-66. 2003..Recent data support the concept that the tissue organization in the rheumatoid joint fosters a breakdown in self-tolerance by promoting a phase transition from self-limited immune responses to self-perpetuating autoimmune responses...
NK-cell-associated receptor expression in hepatosplenic T-cell lymphoma, insights into pathogenesisW G Morice
Leukemia 20:883-6. 2006
The prevalence of IG translocations and 7q32 deletions in splenic marginal zone lymphomaE D Remstein
Leukemia 22:1268-72. 2008
Primary pulmonary MALT lymphomas show frequent and heterogeneous cytogenetic abnormalities, including aneuploidy and translocations involving API2 and MALT1 and IGH and MALT1E D Remstein
Divisions of Anatomic Pathology and Hematopathology, Mayo Clinic, Rochester, MN 55905, USA
Leukemia 18:156-60. 2004..Ectopic nuclear bcl-10 expression is associated with API2-MALT1 but may also be seen in IGH-MALT1 fusion-positive, aneuploidy-only, and normal cases...
Novel FISH probes designed to detect IGK-MYC and IGL-MYC rearrangements in B-cell lineage malignancy identify a new breakpoint cluster region designated BVR2R R Einerson
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
Leukemia 20:1790-9. 2006..In light of the discovery of the distally located BVR2 breakpoint cluster region, it is important to use MYC FISH probes that cover a breakpoint region at least 1.0 Mb 3' of MYC...
