L E Krahn

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. ncbi Narcolepsy: new understanding of irresistible sleep
    L E Krahn
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minn 55905, USA
    Mayo Clin Proc 76:185-94. 2001
  2. ncbi Psychiatric and psychosocial aspects of liver transplantation
    Lois E Krahn
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Scottsdale, AZ 85259, USA
    Liver Transpl 11:1157-68. 2005
  3. ncbi Patients who strive to be ill: factitious disorder with physical symptoms
    Lois E Krahn
    Department of Psychiatry and Psychology and the Section of Biostatistics, Mayo Clinic, Tochester, MN 55905, USA
    Am J Psychiatry 160:1163-8. 2003
  4. ncbi Reevaluating spells initially identified as cataplexy
    Lois E Krahn
    Mayo Clinic in Scottsdale AZ, Mayo Clinic College of Medicine, 13400 East Shea Boulevard, Scottsdale, AZ 85234, USA
    Sleep Med 6:537-42. 2005
  5. ncbi Hypocretin (orexin) levels in cerebrospinal fluid of patients with narcolepsy: relationship to cataplexy and HLA DQB1*0602 status
    Lois E Krahn
    Mayo Clinic, Department of Psychiatry and Psychology, Rochester, MN 55905, USA
    Sleep 25:733-6. 2002
  6. ncbi Rapid resolution of intense suicidal ideation after treatment of severe obstructive sleep apnea
    Lois E Krahn
    Department of Psychiatry and Psychology, Mayo Clinic, Scottsdale, AZ 85259, USA
    J Clin Sleep Med 4:64-5. 2008
  7. ncbi Looking toward DSM-V: should factitious disorder become a subtype of somatoform disorder?
    Lois E Krahn
    Department of Psychiatry and Psychology, 13400 East Shea Blvd, Scottsdale, AZ 85259, USA
    Psychosomatics 49:277-82. 2008
  8. ncbi Modafinil's use in combating interferon-induced fatigue
    Kari A Martin
    Department of Psychiatry and Psychology, Mayo Clinic Arizona, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA
    Dig Dis Sci 52:893-6. 2007
  9. ncbi Cataplexy Emotional Trigger Questionnaire (CETQ)--a brief patient screen to identify cataplexy in patients with narcolepsy
    Wendy R Moore
    Sleep Disorders Center, Department of Nursing, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Clin Sleep Med 3:37-40. 2007
  10. ncbi Selective serotonin reuptake inhibitors in the context of hepatitis C infection: reexamining the risks of bleeding
    Kari A Martin
    Department of Psychiatry and Psychology, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA
    J Clin Psychiatry 68:1024-6. 2007

Detail Information

Publications29

  1. ncbi Narcolepsy: new understanding of irresistible sleep
    L E Krahn
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minn 55905, USA
    Mayo Clin Proc 76:185-94. 2001
    ..This article reviews the current understanding of the diagnosis and treatment of narcolepsy and discusses the possible implications of the hypocretin discovery...
  2. ncbi Psychiatric and psychosocial aspects of liver transplantation
    Lois E Krahn
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Scottsdale, AZ 85259, USA
    Liver Transpl 11:1157-68. 2005
  3. ncbi Patients who strive to be ill: factitious disorder with physical symptoms
    Lois E Krahn
    Department of Psychiatry and Psychology and the Section of Biostatistics, Mayo Clinic, Tochester, MN 55905, USA
    Am J Psychiatry 160:1163-8. 2003
    ..Clinical suspicion is highest for female health care workers in the fourth decade of life. This study was designed to analyze the diagnosis of factitious disorder, the demographics of affected patients, and intervention and treatment...
  4. ncbi Reevaluating spells initially identified as cataplexy
    Lois E Krahn
    Mayo Clinic in Scottsdale AZ, Mayo Clinic College of Medicine, 13400 East Shea Boulevard, Scottsdale, AZ 85234, USA
    Sleep Med 6:537-42. 2005
    ..Relatively little attention has been given to the differential diagnosis of cataplexy, which increases the likelihood of unnecessary sleep testing or false positive diagnosis...
  5. ncbi Hypocretin (orexin) levels in cerebrospinal fluid of patients with narcolepsy: relationship to cataplexy and HLA DQB1*0602 status
    Lois E Krahn
    Mayo Clinic, Department of Psychiatry and Psychology, Rochester, MN 55905, USA
    Sleep 25:733-6. 2002
    ..5%) and more specifically with patients with cataplexy who are HLA DQB1*0602 positive (95.7%). The relationship between hypocretin-1 levels and narcolepsy without cataplexy or the DQB1*0602 allele is less clear...
  6. ncbi Rapid resolution of intense suicidal ideation after treatment of severe obstructive sleep apnea
    Lois E Krahn
    Department of Psychiatry and Psychology, Mayo Clinic, Scottsdale, AZ 85259, USA
    J Clin Sleep Med 4:64-5. 2008
    ..Suicidal ideation and depression resolved promptly and at 4-month followup were in remission. Further studies examining the relationship among untreated obstructive sleep apnea, depression, and suicidal ideation are warranted...
  7. ncbi Looking toward DSM-V: should factitious disorder become a subtype of somatoform disorder?
    Lois E Krahn
    Department of Psychiatry and Psychology, 13400 East Shea Blvd, Scottsdale, AZ 85259, USA
    Psychosomatics 49:277-82. 2008
    ....
  8. ncbi Modafinil's use in combating interferon-induced fatigue
    Kari A Martin
    Department of Psychiatry and Psychology, Mayo Clinic Arizona, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA
    Dig Dis Sci 52:893-6. 2007
    ..We conclude that neurovegetative symptoms are relatively treatment refractory to antidepressants, occur early in the course of treatment, and tend to persist for the duration of therapy [1]...
  9. ncbi Cataplexy Emotional Trigger Questionnaire (CETQ)--a brief patient screen to identify cataplexy in patients with narcolepsy
    Wendy R Moore
    Sleep Disorders Center, Department of Nursing, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Clin Sleep Med 3:37-40. 2007
    ..We hypothesized that the brief questionnaire could provide a quick, sensitive, and specific screening tool to identify those patients with cataplexy, which would result in more timely referrals for further diagnostic testing...
  10. ncbi Selective serotonin reuptake inhibitors in the context of hepatitis C infection: reexamining the risks of bleeding
    Kari A Martin
    Department of Psychiatry and Psychology, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA
    J Clin Psychiatry 68:1024-6. 2007
    ..Prior studies have cautioned against the combined use of SSRIs and interferon due to increased risk of hemorrhage. Given the morbidity of depression and its impact on interferon compliance, we sought to reexamine the data...
  11. ncbi Psychiatric manifestations of Creutzfeldt-Jakob disease: a 25-year analysis
    Christopher A Wall
    Department of Psychiatry and Psychology, Mayo Clinic, Mayo Building W11A, 200 First Street SW, Rochester, MN 55905, USA
    J Neuropsychiatry Clin Neurosci 17:489-95. 2005
    ..Psychiatric manifestations are an early and prominent feature of sporadic CJD, often occurring prior to formal diagnosis...
  12. ncbi Analysis of hypocretin (orexin) antibodies in patients with narcolepsy
    John L Black
    Psychogenomics Laboratory, Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN, USA
    Sleep 28:427-31. 2005
    ..We tested the hypothesis that patients with narcolepsy have serum antibodies specific for preprohypocretin and its derivatives...
  13. ncbi Studies of humoral immunity to preprohypocretin in human leukocyte antigen DQB1*0602-positive narcoleptic subjects with cataplexy
    John L Black
    Psychogenomics Laboratory, Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Biol Psychiatry 58:504-9. 2005
    ..We tested the hypothesis that DQB1*0602-positive narcoleptic subjects with cataplexy have immunoglobulin (Ig)G reactive to human preprohypocretin and its cleavage products...
  14. ncbi A preliminary fluorodeoxyglucose positron emission tomography study in healthy adults reporting dream-enactment behavior
    Richard J Caselli
    Department of Neurology, Mayo Clinic, Scottsdale, Arizona 85259, USA
    Sleep 29:927-33. 2006
    ..To test the hypothesis that healthy adults reporting dream-enactment behavior (DEB+) have reduced cerebral metabolic rate for glucose (CMRgl) in regions preferentially affected in patients with dementia with Lewy bodies (DLB)...
  15. ncbi Carisoprodol withdrawal after internet purchase
    Mackram F Eleid
    Department of Internal Medicine, Mayo Clinic, Scottsdale, Arizona, USA
    Neurologist 16:262-4. 2010
    ....
  16. ncbi A putative link between childhood narcolepsy and obesity
    Suresh Kotagal
    The Sleep Disorders Center, Mayo Clinic, Rochester, MN 55905, USA
    Sleep Med 5:147-50. 2004
    ..While there have been anecdotal observations of binge eating in childhood-onset narcolepsy, the possible relationship between increased weight gain and childhood-onset narcolepsy has not been evaluated...
  17. ncbi The epidemiology of narcolepsy in Olmsted County, Minnesota: a population-based study
    Michael H Silber
    Sleep Disorders Center, Department of Neurology, Mayo Clinic and Mayo Medical School, Rochester, Minnesota 55905, USA
    Sleep 25:197-202. 2002
    ..To determine the age- and sex-specific incidence rates and prevalence of narcolepsy in a United States community...
  18. ncbi Sleep disorders
    Lois E Krahn
    Department of Psychiatry and Psychology, Mayo Sleep Disorders Center, Mayo Clinic Scottsdale, Scottsdale, Arizona 85259, USA
    Semin Neurol 23:307-14. 2003
    ..The discussion provides data regarding the epidemiology, pathophysiology, and diagnostic approach for these conditions. The various treatment options for these sleep disorders are also identified...
  19. ncbi Search for neuron-specific and nonneuron-specific antibodies in narcoleptic patients with and without HLA DQB1*0602
    John Logan Black
    Department of Psychiatry, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Sleep 25:719-23. 2002
    ....
  20. ncbi Characterizing the emotions that trigger cataplexy
    Lois E Krahn
    Mayo Clinic Scottsdale, 13400 E Shea Blvd, Scottsdale, AZ 85259, USA
    J Neuropsychiatry Clin Neurosci 17:45-50. 2005
    ..These selected questions could subsequently be included into screening tools for use with different patient populations...
  21. ncbi Narcolepsy with cataplexy
    Lois E Krahn
    Department of Psychiatry and Psychology, Mayo Clinic, 13400 East Shea Blvd, Scottsdale, AZ 85259, USA
    Am J Psychiatry 161:2181-4. 2004
  22. ncbi Risks of high-dose stimulants in the treatment of disorders of excessive somnolence: a case-control study
    R Robert Auger
    Sleep Disorders Center, Mayo Clinic College of Medicine, Rochester, MN, USA
    Sleep 28:667-72. 2005
    ..Tachyarrhythmias and anorexia or weight loss were also more common in this group as compared with controls. Clinicians should be very cautious in prescribing dosages that exceed maximum guidelines...
  23. ncbi Voltage-gated calcium channel gamma 2 subunit gene is not deleted in velo-cardio-facial syndrome
    J L Black
    Department of Psychiatry and Psychology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Mol Psychiatry 6:461-4. 2001
    ..The location of the gamma 2 subunit gene at 22q13.1 was confirmed by FISH in all cases. This study did not show a deletion of the gamma 2 subunit gene as a distinguishing feature of our patient with VCFS and schizophrenia...
  24. ncbi Narcolepsy associated with other central nervous system disorders
    S Malik
    Sleep Disorders Center, Mayo Clinic, Rochester, MN 55905, USA
    Neurology 57:539-41. 2001
    ..When they occur together, narcolepsy and other CNS disorders frequently emerge at about the same time, suggesting a causative relationship. Hypothalamic-pituitary pathology was the most common association...
  25. ncbi Long-term survival of patients with anorexia nervosa: a population-based study in Rochester, Minn
    Sergio R Korndörfer
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minn 55905, USA
    Mayo Clin Proc 78:278-84. 2003
    ..To estimate long-term survival of unselected patients with anorexia nervosa from Rochester, Minn...
  26. ncbi Smokeless tobacco use among addiction patients: a brief report
    Maria I Lapid
    Mayo Clinic, Department of Psychiatry and Psychology, Rochester, MN 55905, USA
    J Addict Dis 21:27-33. 2002
    ..Further research is needed into effective long-term treatment for ST use among addiction or psychiatric patients...
  27. ncbi The effect of nicotine patch therapy on depression in nonsmokers: a preliminary study
    Lisa Sanderson Cox
    Nicotine Research Center, Mayo Clinic, Rochester, MN 55905, USA
    J Addict Dis 22:75-85. 2003
    ..Among the placebo participants, the mean HRSD score decreased (p = 0.038) by Day 2. The study needs replication with a larger sample and utilizing novel recruitment strategies...
  28. ncbi Psychiatric disorders associated with disturbed sleep
    Lois E Krahn
    Mayo College of Medicine, Scottsdale, AZ 85259, USA
    Semin Neurol 25:90-6. 2005
    ..Treatment plans should take into account the nature of sleep symptomatology as well as the effect of medications on sleep. Ideally, management should include a combination of medications and behavioral treatment...
  29. ncbi HLA DQB1*0602 positive narcoleptic subjects with cataplexy have CSF lgG reactive to rat hypothalamic protein extract
    John L Black
    Sleep 28:1191-2. 2005