Christopher J Klein

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. pmc DNMT1 mutation hot spot causes varied phenotypes of HSAN1 with dementia and hearing loss
    Christopher J Klein
    Department of Neurology, Division of Peripheral Nerve Diseases, Mayo Clinic, Rochester, MN, USA
    Neurology 80:824-8. 2013
  2. pmc Insights from LGI1 and CASPR2 potassium channel complex autoantibody subtyping
    Christopher J Klein
    Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, USA
    JAMA Neurol 70:229-34. 2013
  3. pmc Infrequent SCN9A mutations in congenital insensitivity to pain and erythromelalgia
    Christopher J Klein
    Department of Neurology, Division of Peripheral Nerve Diseases, Mayo Clinic, Rochester, MN 55905, USA
    J Neurol Neurosurg Psychiatry 84:386-91. 2013
  4. pmc Surgical and postpartum hereditary brachial plexus attacks and prophylactic immunotherapy
    Christopher J Klein
    Department of Neurology, Division of Peripheral Nerve Diseases and Medical Genetics, Mayo Clinic Foundation, 200 First Street S W, Rochester, Minnesota, USA
    Muscle Nerve 47:23-7. 2013
  5. pmc Chronic pain as a manifestation of potassium channel-complex autoimmunity
    Christopher J Klein
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Neurology 79:1136-44. 2012
  6. pmc TRPV4 mutations and cytotoxic hypercalcemia in axonal Charcot-Marie-Tooth neuropathies
    C J Klein
    Department of Neurology and Division of Peripheral Nerve Diseases, Mayo Clinic Foundation, Rochester, MN 55905, USA
    Neurology 76:887-94. 2011
  7. pmc Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss
    Christopher J Klein
    Mayo Clinic, Department of Neurology, Division of Peripheral Nerve Diseases, Rochester, Minnesota, USA
    Nat Genet 43:595-600. 2011
  8. pmc SEPT9 mutations and a conserved 17q25 sequence in sporadic and hereditary brachial plexus neuropathy
    Christopher J Klein
    Peripheral Neuropathy Research Laboratory, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Arch Neurol 66:238-43. 2009
  9. pmc SPTLC1 and RAB7 mutation analysis in dominantly inherited and idiopathic sensory neuropathies
    C J Klein
    The Peripheral Neuropathy Research Laboratory, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Neurol Neurosurg Psychiatry 76:1022-4. 2005
  10. ncbi request reprint Genetic testing in inherited peripheral neuropathies
    Christopher J Klein
    Peripheral Neuropathy Research Laboratory, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Peripher Nerv Syst 10:77-84. 2005

Detail Information

Publications62

  1. pmc DNMT1 mutation hot spot causes varied phenotypes of HSAN1 with dementia and hearing loss
    Christopher J Klein
    Department of Neurology, Division of Peripheral Nerve Diseases, Mayo Clinic, Rochester, MN, USA
    Neurology 80:824-8. 2013
    ..The chromosomal location of the DNMT1 gene at 19p13.2 has been linked to familial late-onset Alzheimer disease...
  2. pmc Insights from LGI1 and CASPR2 potassium channel complex autoantibody subtyping
    Christopher J Klein
    Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, USA
    JAMA Neurol 70:229-34. 2013
    ....
  3. pmc Infrequent SCN9A mutations in congenital insensitivity to pain and erythromelalgia
    Christopher J Klein
    Department of Neurology, Division of Peripheral Nerve Diseases, Mayo Clinic, Rochester, MN 55905, USA
    J Neurol Neurosurg Psychiatry 84:386-91. 2013
    ..We sought to investigate for SCN9A mutations in a clinically well-characterised cohort of patients with CIP and erythromelalgia...
  4. pmc Surgical and postpartum hereditary brachial plexus attacks and prophylactic immunotherapy
    Christopher J Klein
    Department of Neurology, Division of Peripheral Nerve Diseases and Medical Genetics, Mayo Clinic Foundation, 200 First Street S W, Rochester, Minnesota, USA
    Muscle Nerve 47:23-7. 2013
    ..Surgery and childbirth can trigger attacks of hereditary brachial plexus neuropathy (HBPN), and inflammation was suggested as a component of the pathogenesis...
  5. pmc Chronic pain as a manifestation of potassium channel-complex autoimmunity
    Christopher J Klein
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Neurology 79:1136-44. 2012
    ..Autoantibodies targeting voltage-gated potassium channel (VGKC) complexes cause a spectrum of neuronal hyperexcitability disorders. We investigated pain as a manifestation of VGKC-complex autoimmunity...
  6. pmc TRPV4 mutations and cytotoxic hypercalcemia in axonal Charcot-Marie-Tooth neuropathies
    C J Klein
    Department of Neurology and Division of Peripheral Nerve Diseases, Mayo Clinic Foundation, Rochester, MN 55905, USA
    Neurology 76:887-94. 2011
    ..To improve understanding of TRPV4-associated axonal Charcot-Marie-Tooth (CMT) neuropathy phenotypes and their debated pathologic mechanism...
  7. pmc Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss
    Christopher J Klein
    Mayo Clinic, Department of Neurology, Division of Peripheral Nerve Diseases, Rochester, Minnesota, USA
    Nat Genet 43:595-600. 2011
    ..Our study shows that DNMT1 mutations cause the aberrant methylation implicated in complex pathogenesis. The discovered DNMT1 mutations provide a new framework for the study of neurodegenerative diseases...
  8. pmc SEPT9 mutations and a conserved 17q25 sequence in sporadic and hereditary brachial plexus neuropathy
    Christopher J Klein
    Peripheral Neuropathy Research Laboratory, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Arch Neurol 66:238-43. 2009
    ..These mutations were not found in North American kindreds with H-BPN with a conserved 500-kilobase sequence of DNA at the 17q25 chromosomal region (where SEPT9 localizes) where a founder mutation has been suggested...
  9. pmc SPTLC1 and RAB7 mutation analysis in dominantly inherited and idiopathic sensory neuropathies
    C J Klein
    The Peripheral Neuropathy Research Laboratory, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Neurol Neurosurg Psychiatry 76:1022-4. 2005
    ..Some cases of idiopathic sensory neuropathy could be caused by missense mutations of SPTLC1 and RAB7 and not be recognised as familial...
  10. ncbi request reprint Genetic testing in inherited peripheral neuropathies
    Christopher J Klein
    Peripheral Neuropathy Research Laboratory, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Peripher Nerv Syst 10:77-84. 2005
  11. pmc Mass spectrometric-based proteomic analysis of amyloid neuropathy type in nerve tissue
    Christopher J Klein
    Department of Neurology Peripheral Nerve Laboratory, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Arch Neurol 68:195-9. 2011
    ..To determine the specific type of amyloid from nerve biopsies using laser microdissection (LMD) and mass spectrometric (MS)-based proteomic analysis...
  12. pmc Inflammation and neuropathic attacks in hereditary brachial plexus neuropathy
    C J Klein
    Peripheral Neuropathy Research Center, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Neurol Neurosurg Psychiatry 73:45-50. 2002
    ....
  13. ncbi request reprint The inherited neuropathies
    Christopher J Klein
    Department of Neurology, Division of Peripheral Nerve Diseases, Mayo Clinic, Rochester, MN, USA
    Neurol Clin 25:173-207. 2007
    ..the rapidity of the ongoing discovery requires clinicians to be familiar with molecular biologic discoveries and consider wisely which testing should be performed...
  14. ncbi request reprint The gene for HMSN2C maps to 12q23-24: a region of neuromuscular disorders
    C J Klein
    Peripheral Neuropathy Research Laboratory, Mayo Clinic and Mayo Foundation, Rochester, MN, USA
    Neurology 60:1151-6. 2003
    ..Hereditary motor and sensory neuropathy type 2C (HMSN2C, Charcot-Marie-Tooth 2C [CMT2C]) is an autosomal dominant motor and sensory neuropathy involving limb, diaphragm, vocal cord, and intercostal muscles...
  15. ncbi request reprint Adult polyglucosan body disease: case description of an expanding genetic and clinical syndrome
    Christopher J Klein
    Department of Neurology, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 29:323-8. 2004
    ..These findings expand the clinical and genetic spectrum of APBD. Factors other than mutation of the expressed GBE gene may cause enzyme deficiency and varied expression and development of APBD...
  16. ncbi request reprint Pathology and molecular genetics of inherited neuropathy
    Christopher J Klein
    Department of Neurology, Mayo Clinic, Guggenheim 811, 200 First Street, Rochester, MN 55905, USA
    J Neurol Sci 220:141-3. 2004
  17. pmc Large kindred evaluation of mitofusin 2 novel mutation, extremes of neurologic presentations, and preserved nerve mitochondria
    Christopher J Klein
    Division of Neuroimmunology, Department of Medical Genetics, Mayo Clinic, Rochester, MN 55905, USA
    Arch Neurol 68:1295-302. 2011
    ..The results of the nerve biopsy specimens suggested that the mitochondria are structurally abnormal in patients with MFN2 mutations...
  18. pmc The neuropathies of Waldenström's macroglobulinemia (WM) and IgM-MGUS
    Christopher J Klein
    Peripheral Nerve Research Laboratory, Department of Hematology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Can J Neurol Sci 38:289-95. 2011
    ..Paraneoplastic or paraimmune mechanisms are thought to be involved in the pathogenesis of these neuropathies. Attempts at distinguishing WM and IgM-MGUS neuropathies are lacking especially among bone marrow (BM) confirmed patients...
  19. doi request reprint Antibodies to myelin-associated glycoprotein (anti-Mag) in IgM amyloidosis may influence expression of neuropathy in rare patients
    Mercedes Garces-Sanchez
    Peripheral Nerve Research Laboratory, Mayo Clinic, Rochester, MN 55905, USA
    Muscle Nerve 37:490-5. 2008
    ..They do not appear to affect the occurrence or expression of polyneuropathy, except possibly in occasional cases with WB positivity...
  20. pmc Signs and symptoms versus nerve conduction studies to diagnose diabetic sensorimotor polyneuropathy: Cl vs. NPhys trial
    Peter J Dyck
    Peripheral Neuropathy Research Laboratory, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 42:157-64. 2010
    ..Study physician dx from signs and symptoms were excessively variable, often overestimating DSPN. Specific approaches to improving clinical proficiency should be tested...
  21. pmc Amyloid-like IgM deposition neuropathy: a distinct clinico-pathologic and proteomic profiled disorder
    Juan J Figueroa
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    J Peripher Nerv Syst 17:182-90. 2012
    ..Patients have favorable survival, relative absence of autonomic features, and distinct proteomic profiles of the infiltrative protein in nerve...
  22. ncbi request reprint Cramp-fasciculation syndrome in patients with and without neural autoantibodies
    Teerin Liewluck
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905, USA Department of Neurology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, USA
    Muscle Nerve 49:351-6. 2014
    ..Antibody positivity was associated with extramuscular manifestations, typically without malignancy. Target antigens within the VGKC complex remain unknown in most patients. Muscle Nerve 49:351-356, 2014. ..
  23. pmc Multicenter trial of the proficiency of smart quantitative sensation tests
    Peter J Dyck
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, USA, 55905
    Muscle Nerve 49:645-53. 2014
    ..We assessed proficiency (accuracy and intra- and intertest reproducibility) of smart quantitative sensation tests (smart QSTs) in subjects without and with diabetic sensorimotor polyneuropathy (DSPN)...
  24. pmc Impaired glycemia and diabetic polyneuropathy: the OC IG Survey
    Peter J Dyck
    Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
    Diabetes Care 35:584-91. 2012
    ....
  25. ncbi request reprint Post-surgical inflammatory neuropathy
    Nathan P Staff
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Brain 133:2866-80. 2010
    ..In 13 cases with longitudinal follow-up (median 9 months, range 3-71 months), the median neuropathy impairment score improved from 30 to 24 at the time of last evaluation (P=0.001)...
  26. ncbi request reprint Identification of transthyretin variants by sequential proteomic and genomic analysis
    H Robert Bergen
    WM Keck FT ICR Mass Spectrometry Laboratory, Mayo Proteomics Research Center, Mayo Clinic College of Medicine, Rochester, MN, USA
    Clin Chem 50:1544-52. 2004
    ....
  27. doi request reprint Purkinje cell cytoplasmic autoantibody type 1 accompaniments: the cerebellum and beyond
    Andrew McKeon
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Arch Neurol 68:1282-9. 2011
    ..To investigate the full extent of Purkinje cell cytoplasmic autoantibody type 1 autoimmunity (classically associated with paraneoplastic cerebellar degeneration) from clinical, immunohistochemical, and neuropathological perspectives...
  28. ncbi request reprint Modeling chronic glycemic exposure variables as correlates and predictors of microvascular complications of diabetes
    Peter J Dyck
    Mayo Clinic College of Medicine, Department of Neurology, 200 First St SW, Rochester, MN 55905, USA
    Diabetes Care 29:2282-8. 2006
    ..Specifically, we test whether combinations of components correlate and predict complications better than individual components...
  29. ncbi request reprint Disseminated sporotrichosis presenting with granulomatous inflammatory multiple mononeuropathies
    Michelle L Mauermann
    Department of Neurology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 36:866-72. 2007
    ..Based on clinical and pathological features, the mechanism of neuropathy may have been due to either direct nerve infection or a bystander effect of inflammatory/immune damage or, perhaps more likely, to both mechanisms...
  30. ncbi request reprint Isolated amyloidosis presenting with lumbosacral radiculoplexopathy: description of two cases and pathogenic review
    Shafeeq S Ladha
    Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Peripher Nerv Syst 11:346-52. 2006
    ..The limited literature and experience among other cases is described...
  31. ncbi request reprint Novel myelin protein zero mutation (Arg36Trp) in a patient with acute onset painful neuropathy
    Ted M Burns
    Department of Neurology, University of Virginia, Hospital Drive, McKim Hall, P O Box 800394, Charlottesville, VA 22908, USA
    Neuromuscul Disord 16:308-10. 2006
    ..We predict that other rapid symptom onset polyneuropathies will be found to have direct genetic susceptibility...
  32. pmc A trial of proficiency of nerve conduction: greater standardization still needed
    Peter J Dyck
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905, USA
    Muscle Nerve 48:369-74. 2013
    ..The aim of this study was to test the proficiency (accuracy among evaluators) of measured attributes of nerve conduction (NC)...
  33. pmc Epidermal nerve fibers: confidence intervals and continuous measures with nerve conduction
    JaNean K Engelstad
    Peripheral Neuropathy Research Laboratory, Mayo Clinic, Rochester, MN, USA
    Neurology 79:2187-93. 2012
    ..Our second objective was to introduce a new continuous measure combining nerve conduction and ENFs/mm...
  34. pmc Voltage-gated potassium channel autoimmunity mimicking creutzfeldt-jakob disease
    Michael D Geschwind
    Neuroimmunology Laboratory, Hilton 3 78F, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Arch Neurol 65:1341-6. 2008
    ..Rapidly progressive dementia has a variety of causes, including Creutzfeldt-Jakob disease (CJD) and neuronal voltage-gated potassium channel (VGKC) autoantibody-associated encephalopathy...
  35. pmc Chronic meralgia paresthetica and neurectomy: a clinical pathologic study
    Sarah E Berini
    From the Peripheral Neuropathy Research Laboratory S E B, J K E, N P S, N S, P J B D, C J K, the Department of Neurosurgery R J S, and the Department of Anatomic Pathology M E J, Mayo Clinic and Mayo Foundation, Rochester, MN
    Neurology 82:1551-5. 2014
    ..To understand the pathologic and clinical correlates of patients with chronic meralgia paresthetica (MP) undergoing lateral femoral cutaneous nerve (LFCN) neurectomy...
  36. pmc Ubiquitin ligase defect by DCAF8 mutation causes HMSN2 with giant axons
    Christopher J Klein
    From the Peripheral Nerve Laboratory C J K, X D, P J D, Laboratory Medicine and Pathology Y W, Department of Biochemistry and Molecular Biology M V B, G M, and Biomedical Statistics and Informatics S M, E J A, Mayo Clinic, Rochester, MN Department of Neurology P V, St Georg Hospital, Hamburg, Germany Department of Neuropathology H H G, Charite Universitatsmedizin, Berlin, Germany and Neurogenetics Branch C B, K Z, National Institute of Neurological Disorders and Stroke, Bethesda, MD
    Neurology 82:873-8. 2014
    ..To identify the genetic cause of axonal hereditary motor and sensory neuropathy (HMSN2) with infrequent giant axons...
  37. pmc IgM-monoclonal gammopathy neuropathy and tremor: a first epidemiologic case control study
    Matthew C Ahlskog
    Peripheral Nerve Research Laboratory, Mayo Clinic, Department of Neurology, 200 First Street SW, Rochester, MN 55905, USA
    Parkinsonism Relat Disord 18:748-52. 2012
    ..Epidemiologic study to confirm this association is lacking. Whether the neuropathy or another remote IgM-effect is causal remains unsettled...
  38. pmc Mass spectrometry analysis reveals non-mutated apolipoprotein A1 lumbosacral radiculoplexus amyloidoma
    Adam J Loavenbruck
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 46:817-22. 2012
    ..In all known reported cases, peripheral nerve amyloidomas have had immunoglobulin light-chain fibril composition and occurred in the context of paraproteinemia...
  39. doi request reprint Striational antibodies in a paraneoplastic context
    Andrew McKeon
    Department of Medicine and Pathology, Mayo Clinic, Hilton 3 78, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 47:585-7. 2013
    ..The clinical significance of striational antibodies (StrAbs) detected in the course of paraneoplastic antibody testing is unknown...
  40. ncbi request reprint Monotonicity of nerve tests in diabetes: subclinical nerve dysfunction precedes diagnosis of polyneuropathy
    Peter J Dyck
    Department of Neurology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA
    Diabetes Care 28:2192-200. 2005
    ..The objective of this study was to test whether monotone worsening of nerve function, attributable to diabetes, can be demonstrated before criteria for diabetic sensorimotor polyneuropathy (DSPN) have been met. Which nerve tests are best?..
  41. doi request reprint Diabetic cervical radiculoplexus neuropathy: a distinct syndrome expanding the spectrum of diabetic radiculoplexus neuropathies
    Rami Massie
    Department of Neurology, Hopital du Sacre Coeur de Montreal, Montreal, QC, H4J 1C5, Canada
    Brain 135:3074-88. 2012
    ....
  42. doi request reprint Psychiatric manifestations of voltage-gated potassium-channel complex autoimmunity
    Kristin J Somers
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN, USA
    J Neuropsychiatry Clin Neurosci 23:425-33. 2011
    ..Neuropsychiatric presentations were significantly associated with higher autoantibody values. Improvements were most evident in patients treated early, which emphasizes the need for early diagnosis and immunotherapy initiation...
  43. ncbi request reprint Case of mononeuritis multiplex onset with rituximab therapy for Waldenström's macroglobulinemia
    Michelle L Mauermann
    Department of Neurology, Section of Peripheral Nerve, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, United States
    J Neurol Sci 260:240-3. 2007
    ....
  44. pmc Peripheral neuropathy incidence in inflammatory bowel disease: a population-based study
    Juan J Figueroa
    Department of Neurology, Peripheral Nerve Laboratory, Rochester Epidemiology Project, Mayo Clinic, Rochester, MN, USA
    Neurology 80:1693-7. 2013
    ..Our aim was to determine the incidence of peripheral neuropathy in a population-based inflammatory bowel disease (IBD) cohort from Olmsted County, Minnesota...
  45. ncbi request reprint Later-onset Fabry disease: an adult variant presenting with the cramp-fasciculation syndrome
    Christopher S Nance
    Peripheral Neuropathy Research Center and Multiple Sclerosis Research Center, Mayo Clinic, Rochester, Minn, USA
    Arch Neurol 63:453-7. 2006
    ..Later-onset variants with residual alpha-galactosidase A activity lack vascular endothelial involvement and classic symptoms, which lead to the development of cardiac and/or renal disease after the fourth decade of life...
  46. pmc Potassium channel complex autoimmunity induced by inhaled brain tissue aerosol
    Jeffrey W Meeusen
    Department of Laboratory Medicine and Pathology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Ann Neurol 71:417-26. 2012
    ..To test the hypothesis that autoimmunity induced by inhalation of aerosolized brain tissue caused outbreaks of sensory-predominant polyradiculoneuropathy among swine abattoir employees in the Midwestern United States...
  47. ncbi request reprint Elevated creatine kinase and transaminases in asymptomatic SBMA
    Eric J Sorenson
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Amyotroph Lateral Scler 8:62-4. 2007
    ..These cases emphasize the need to consider SBMA and genetic testing for the androgen receptor trinucleotide CAG expansion in males otherwise healthy with 'idiopathic' elevated creatinine kinase...
  48. ncbi request reprint Imaging features of copper deficiency myelopathy: a study of 25 cases
    Neeraj Kumar
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Neuroradiology 48:78-83. 2006
    ..Neuroradiologists should consider this possibility when a long segment of symmetric dorsal spinal cord T2-hyperintensity is identified...
  49. ncbi request reprint Melarsoprol-associated multifocal inflammatory CNS illness in African trypanosomiasis
    N Kumar
    Division of Infectious Diseases, Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Neurology 66:1120-1. 2006
  50. ncbi request reprint Does impaired glucose metabolism cause polyneuropathy? Review of previous studies and design of a prospective controlled population-based study
    Peter J Dyck
    Peripheral Neuropathy Research Laboratory, Mayo Clinic, Rochester, MN 55905, USA
    Muscle Nerve 36:536-41. 2007
    ..Here we review previous studies, list the reasons that the issue needs further study, and outline a study now in progress to address the question more definitively...
  51. doi request reprint A case of sensory ataxia as the presenting manifestation of neurosarcoidosis
    Haatem M Reda
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 43:900-5. 2011
    ..There was clinical and radiographic improvement with corticosteroids. In addition, we review previously reported cases of cauda equina sarcoidosis...
  52. pmc Myelin protein zero mutation His39Pro: hereditary motor and sensory neuropathy with variable onset, hearing loss, restless legs and multiple sclerosis
    D H Kilfoyle
    Peripheral Nerve Group, Department of Neurology, Mayo Clinic, Genotyping Shared Resource Center of Advanced Genomic Technology Center, Rochester, Minnesota 55905, USA
    J Neurol Neurosurg Psychiatry 77:963-6. 2006
    ..Mutations of myelin protein zero (MPZ) may cause inherited neuropathy with variable expression...
  53. pmc Inherited neuropathies: clinical overview and update
    Christopher J Klein
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905, USA Department of Medical Genetics, Mayo Clinic, Rochester, Minnesota, USA
    Muscle Nerve 48:604-22. 2013
    ..A framework is provided for clinical evaluations, including the inheritance assessment, electrophysiologic examinations, and specific genetic tests...
  54. pmc Batch effect correction for genome-wide methylation data with Illumina Infinium platform
    Zhifu Sun
    Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street, Rochester, MN 55905, USA
    BMC Med Genomics 4:84. 2011
    ..To date, little attention has been given to issues related to normalization and batch effect correction for this kind of data...
  55. pmc Meralgia paresthetica: relation to obesity, advanced age, and diabetes mellitus
    Thomas J Parisi
    Department of Graduate Medicine, Mayo Medical School, 200 First Street SW, Rochester, MN 55905, USA
    Neurology 77:1538-42. 2011
    ..To determine the incidence of meralgia paresthetica (MP) and its relationship to diabetes mellitus (DM) and obesity...
  56. ncbi request reprint Progressive multifocal leukoencephalopathy: a rare infectious complication following allogeneic hematopoietic cell transplantation (HCT)
    Gregory P Kaufman
    Department of Medicine, Mayo Clinic, Rochester, MN, USA
    Eur J Haematol 92:83-7. 2014
    ..Here, we present the case of PML following allogeneic HCT that highlights potential diagnostic difficulties. We also review the literature regarding PML following HCT and described therapies employed to attempt to treat this disorder. ..
  57. ncbi request reprint Neurologic course, endocrine dysfunction and triplet repeat size in spinal bulbar muscular atrophy
    Michael Sinnreich
    Peripheral Neuropathy Research Laboratory, Department of Neurology, Mayo Clinic and Mayo Foundation, Rochester, MN, USA
    Can J Neurol Sci 31:378-82. 2004
    ..To study the role of diabetes, gynecomastia and CAG triplet repeat size as disease modifying factors of neurologic expression in spinal bulbar muscular atrophy (SBMA, Kennedy's disease)...
  58. ncbi request reprint Transthyretin amyloidosis (serine 44) with headache, hearing loss, and peripheral neuropathy
    C J Klein
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Neurology 51:1462-4. 1998
    ..Direct DNA sequencing revealed both the normal TTT (phenylalanine) and a new variant TCT (serine) at position 44 of the TTR gene. This case expands the genotypic and phenotypic variability within TTR amyloidosis...
  59. doi request reprint Clinical spectrum of voltage-gated potassium channel autoimmunity
    K M Tan
    Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Neurology 70:1883-90. 2008
    ..To document neurologic, oncologic, and serologic associations of patients in whom voltage-gated potassium channel (VGKC) autoantibodies were detected in the course of serologic evaluation for neuronal, glial, and muscle autoantibodies...
  60. ncbi request reprint Chronic immune sensory polyradiculopathy: a possibly treatable sensory ataxia
    M Sinnreich
    Peripheral Neuropathy Research Laboratory, Department of Neurology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    Neurology 63:1662-9. 2004
    ..Chronic inflammatory neuropathies can present with a sensory ataxia due to involvement of dorsal root ganglia (DRG) or sensory nerves. Selective inflammatory involvement of sensory nerve roots proximal to the DRG has been postulated...
  61. ncbi request reprint Indifference rather than insensitivity to pain
    Christopher J Klein
    Ann Neurol 53:417-8; author reply 418-9. 2003
  62. ncbi request reprint Lenalidomide therapy in a patient with POEMS syndrome
    Angela Dispenzieri
    Blood 110:1075-6. 2007