Research Topics
| M T KeeganSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Comparison of APACHE III, APACHE IV, SAPS 3, and MPM0III and influence of resuscitation status on model performanceMark T Keegan
Division of Critical Care, Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
Chest 142:851-8. 2012..Only MPM0III includes resuscitation status as a predictor...- Predicting mortality in intensive care unit survivors using a subjective scoring systemBekele Afessa
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Crit Care 11:109. 2007..However, if it is to be generalizable and reproducible and to perform well without bias, then a good prediction model should be based on objectively defined variables... - A prospective trial of elective extubation in brain injured patients meeting extubation criteria for ventilatory support: a feasibility studyEdward M Manno
Department of Neurology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Crit Care 12:R138. 2008..The design is a single-blinded block randomised controlled trial. A single large academic medical centre is the setting... - APACHE III outcome prediction in patients admitted to the intensive care unit after liver transplantation: a retrospective cohort studyMark T Keegan
Division of Critical Care, Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA
BMC Surg 9:11. 2009..The area under the receiver operating characteristic curve (AUC) and the Hosmer-Lemeshow C statistic were used to assess, respectively, discrimination and calibration of APACHE III... 
Is there a role for inhaled nitric oxide as a rescue therapy in respiratory failure associated with hematologic malignancies?Mark T Keegan
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Am J Hematol 81:729-34. 2006..Therefore, despite initial improvement in oxygenation, we did not observe any survival benefit to INO in this setting...
Changes in intensive care unit performance measures associated with opening a dedicated thoracic surgical progressive care unitMark T Keegan
Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 22:347-53. 2008..To determine the effect of the introduction of a specialty-specific progressive care unit (PCU) on the intensive care unit (ICU) to which relatively low-acuity patients had previously been admitted...- The acute physiology and chronic health evaluation III outcome prediction in patients admitted to the intensive care unit after pneumonectomyMark T Keegan
Department of Anesthesia, Division of Critical Care, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 21:832-7. 2007..The purpose of this study was to determine if the APACHE III predicts hospital mortality after pneumonectomy... - Serum vasopressin concentrations during orthotopic liver transplantationM T Keegan
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Transplant Proc 42:2594-8. 2010..We report measurements of the temporal response of serum vasopressin concentrations in the period after reperfusion of the liver graft during orthotopic liver transplantation (OLT)... - Safety and effectiveness of intensive insulin protocol use in post-operative liver transplant recipientsM T Keegan
Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Transplant Proc 42:2617-24. 2010..We conclude that nurse-initiated and -directed glycemic control protocols can be safely and effectively used in the early period after OLT, though we did not identify a beneficial effect on graft function... - Sodium, potassium and glucose management in organ transplantationMark T Keegan
Division of Critical Care, Department of Anesthesiology, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Curr Opin Organ Transplant 15:383-9. 2010..To present current knowledge about the metabolic management of patients undergoing solid organ transplantation, and potential organ donors... - Critical care issues following orthotopic liver transplantationM T Keegan
Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA
Minerva Gastroenterol Dietol 56:305-30. 2010..The review concludes with a discussion of the additional challenges practitioners face when dealing with living donor liver transplantation and donation after cardiac death... - Osteogenesis imperfecta, perioperative bleeding, and desmopressinMark T Keegan
Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Anesthesiology 97:1011-3. 2002 - Acute Physiology and Chronic Health Evaluation (APACHE) III outcome prediction after major vascular surgeryMark T Keegan
Department of Anesthesiology, Division of Critical Care, Mayo Clinic, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 22:713-8. 2008..To investigate the performance of the Acute Physiology and Chronic Health Evaluation (APACHE) III scoring system in patients admitted to the intensive care unit (ICU) after major vascular surgery... - Mortality rate and length of stay of patients admitted to the intensive care unit in JulyJavier D Finkielman
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Medical School, Mayo Clinic and Foundation, 200 First St. SW, Rochester, MN 55905, USA
Crit Care Med 32:1161-5. 2004..CONCLUSIONS: ICU admission in July is not associated with increased hospital mortality rate or ICU length of stay... - The association between nighttime transfer from the intensive care unit and patient outcomeTarik Hanane
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA
Crit Care Med 36:2232-7. 2008..To determine the impact of nighttime transfer of patients from the intensive care unit (ICU) on clinical outcome... - Perioperative and critical illness dysglycemia--controlling the icebergMark T Keegan
Mayo Clinic, Rochester, Minnesota, USA
J Diabetes Sci Technol 3:1288-91. 2009.... - Fast track anesthesia for liver transplantation reduces postoperative ventilation time but not intensive care unit stayJames Y Findlay
Department of Anesthesiology and Critical Care, Mayo Clinic, Rochester, MN 55905, USA
Liver Transpl 8:670-5. 2002..We conclude that a fast track approach to anesthetic care reduces the requirement for postoperative mechanical ventilation, but does not reduce intensive care unit stay after liver transplantation... - Liver transplantation for massive hepatic haemangiomatosis causing restrictive lung diseaseM T Keegan
Department of Anesthesiology and Critical Care, Mayo Clinic, Rochester, MN 55905, USA
Br J Anaesth 86:431-4. 2001..Weaning from mechanical ventilation was impaired by acute and chronic metabolic alkalosis, and diaphragmatic laxity... - Preoperative dobutamine stress echocardiography, intraoperative events, and intraoperative myocardial injury in liver transplantationJ Y Findlay
Department of Anesthesiology, Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, 200 Second Street SW, Rochester, MN 55905, USA
Transplant Proc 37:2209-13. 2005..CONCLUSION: When used in accordance with our protocol a positive DSE does not reliably identify patients at high cardiac risk during liver transplantation, but a negative DSE is strongly predictive of no myocardial injury... - Comparison of community and referral intensive care unit patients in a tertiary medical center: evidence for referral bias in the critically illEdward G Seferian
Division of Pediatric Critical Care Medicine, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA
Crit Care Med 36:2779-86. 2008.... - Association between ICU admission during morning rounds and mortalityBekele Afessa
Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, USA
Chest 136:1489-95. 2009..No previous study has evaluated the association between admission to ICUs during round time and patient outcome. The objective of this study was to determine the association between round-time ICU admission and patient outcome... - Resource utilization of total knee arthroplasty patients cared for on specialty orthopedic surgery unitsJohn A Batsis
Division of Primary Care Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
J Hosp Med 3:218-27. 2008..The number and costs of arthoplasty surgeries continue to increase, requiring institutions to reexamine their existing practices for financial sustainability... - The influence of missing components of the Acute Physiology Score of APACHE III on the measurement of ICU performanceBekele Afessa
Division of Pulmonary and Critical Care, Department of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Intensive Care Med 31:1537-43. 2005..To determine the impact of missing Acute Physiology Score (APS) values on risk-adjusted mortality... - Critical care support of patients with nicotine addictionBekele Afessa
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Crit Care 14:155. 2010..Despite the abundance of active smokers, there is a paucity of data describing nicotine withdrawal, and its prevention and treatment options in the critically ill. Future studies are warranted to address these issues... - Severity of illness and organ failure assessment in adult intensive care unitsBekele Afessa
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, 200 First Street, SW, Rochester, MN 55905, USA
Crit Care Clin 23:639-58. 2007..Their roles as clinical decision support tools at the bedside await future studies because of their unknown or poor performance at the individual patient level... - Toward the prevention of acute lung injury: protocol-guided limitation of large tidal volume ventilation and inappropriate transfusionMurat Yilmaz
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Crit Care Med 35:1660-6; quiz 1667. 2007..We evaluated the effect of two quality improvement interventions (low tidal volume ventilation and restrictive transfusion) on the development of acute lung injury in mechanically ventilated patients... - Perioperative statin therapy and renal outcomes after major vascular surgery: a propensity-based analysisDaryl J Kor
Department of Anesthesiology, Division of Critical Care, Mayo Clinic College of Medicine, Rochester, MN, USA
J Cardiothorac Vasc Anesth 22:210-6. 2008..To evaluate how the presence and timing of statin therapy affect perioperative renal outcomes after major vascular surgery... - Postoperative confusion and basilar artery strokeDavid P Martin
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Neurocrit Care 4:147-50. 2006..Non-focal postoperative mental status changes can be challenging... - Vasotrac arterial blood pressure and direct arterial blood pressure monitoring during liver transplantationJames Y Findlay
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester Minnesota 55905, USA
Anesth Analg 102:690-3. 2006..Correlation was 0.82. Vasotrac bias was +3.3 mm Hg and limits of agreement +/-15 mm Hg. We conclude that the Vasotrac is not adequately accurate to substitute for direct arterial blood pressure monitoring in liver transplantation... - Intraoperative tidal volume as a risk factor for respiratory failure after pneumonectomyEvans R Fernandez-Perez
Division of Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Anesthesiology 105:14-8. 2006..The authors hypothesized that intraoperative mechanical ventilation with large tidal volumes (VTs) would be associated with increased risk of postpneumonectomy respiratory failure... - Bronchoscopy in ventilator-associated pneumonia: agreement of calibrated loop and serial dilutionBekele Afessa
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Am J Respir Crit Care Med 173:1229-32. 2006.... - Evaluating the performance of an institution using an intensive care unit benchmarkBekele Afessa
Department of Internal Medicine and Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 80:174-80. 2005..To describe the performances of selected intensive care units (ICUs) in a single institution using the Acute Physiology and Chronic Health Evaluation (APACHE) III benchmark and to propose interventions that may improve performance... - Identifying potentially ineffective care in the sickest critically ill patients on the third ICU dayBekele Afessa
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Chest 126:1905-9. 2004..To determine if an increase in the third-ICU-day acute physiology score (APS) of the APACHE (acute physiology and chronic health evaluation) III prognostic system can identify potentially ineffective care... - The hospital mortality of patients admitted to the ICU on weekendsS Allen Ensminger
Division of Pulmonary and Critical Care Medicine, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
Chest 126:1292-8. 2004..This study was conducted to determine whether weekend admission to the ICU increases the risk of dying in the hospital... - Neuropathy following axillary brachial plexus block: is it the tourniquet?Christopher J Jankowski
Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Anesthesiology 99:1230-2. 2003 - Tracheostomy after major vascular surgeryDaniel A Diedrich
Department of Anesthesiology, Division of Critical Care, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Cardiothorac Vasc Anesth 20:14-9. 2006..These observations should be considered when counseling patients and their families regarding tracheostomy after aortic surgery... - Progression of organ failure in patients approaching brain stem deathF T Lytle
Division of Critical Care, Department of Anesthesiology, Mayo Clinic College of Medicine Rochester, MN, USA
Am J Transplant 9:1446-50. 2009..8 h (9.5-17.6). The fact that mean SOFA scores did not change significantly over time, even after BSD occurred, has implications for the timing of retrieval of organs for transplantation... - Management of the difficult and failed airway in obstetric anesthesiaGurinder M Vasdev
Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
J Anesth 22:38-48. 2008..Worldwide maternal mortality reflects the health of a nation. However, one could also claim that, particularly in Western countries, maternal mortality may reflect the health of the specialty of anesthesia... - Inhaled nitric oxide for acute right-ventricular dysfunction after extrapleural pneumonectomyEvans R Fernandez-Perez
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55095, USA
Respir Care 51:1172-6. 2006..We report the use of inhaled nitric oxide in a patient with acute right-ventricular dysfunction after extrapleural pneumonectomy... - A more aggressive approach to emergency embolectomy for acute pulmonary embolismBasar Sareyyupoglu
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA
Mayo Clin Proc 85:785-90. 2010..To examine operative outcomes after acute pulmonary embolectomy (APE), a recently adopted, more aggressive surgical approach... - Critical care issues in liver transplantationMark T Keegan
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Int Anesthesiol Clin 44:1-16. 2006 - The use of the intubating laryngeal mask endotracheal tube with intubating devicesKirstin M Erickson
Department of Anesthesiology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA
Anesth Analg 95:249-50, table of contents. 2002..The endotracheal tube designed for use with the intubating laryngeal mask airway may facilitate intubation in these circumstances... - Perioperative antibiotics and practice: little things that make a big differenceMark T Keegan
Division of Critical Care Medicine, Department of Anesthesiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Anesthesiol Clin North America 22:473-91. 2004..Many aspects of perioperative care ranging from thermoregulation to glycemic control may have profound longterm affects on infection rate and thereby patient outcome... - The transplant recipient for nontransplant surgeryMark T Keegan
Division of Critical Care, Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Anesthesiol Clin North America 22:827-61. 2004..This article reviews the anesthetic concerns for patients who have undergone a variety of organ transplants... - Six-month survival of patients with acute lung injury: prospective cohort studyMurat Yilmaz
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Crit Care Med 35:2303-7. 2007..We sought to determine the outcome of consecutive acute lung injury patients after the implementation of these interventions... - Prolonged coma from refractory status epilepticusSaqib I Dara
Critical Care Service, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Neurocrit Care 4:140-2. 2006..CONCLUSION: Few evidence-based data exist to guide management of RSE. Our case emphasizes the need for continuous aggressive therapy when neuroimaging remains normal... - Evidence-based red cell transfusion in the critically ill: quality improvement using computerized physician order entryRimki Rana
Family Medicine Residency, Mercy Medical Center-North Iowa, Mason City, IA, USA
Crit Care Med 34:1892-7. 2006..12; 95% confidence interval, 0.69 to 1.8). CONCLUSIONS: The implementation of an institutional protocol and decision support through a computerized provider order entry effectively decreased inappropriate red cell transfusions... - Postoperative coma in a patient with complete basilar syndrome after anterior cervical discectomyDavid P Martin
Can J Anaesth 53:738. 2006