Jerry A Katzmann

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. ncbi request reprint Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains
    Jerry A Katzmann
    Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Clin Chem 48:1437-44. 2002
  2. pmc Suppression of uninvolved immunoglobulins defined by heavy/light chain pair suppression is a risk factor for progression of MGUS
    J A Katzmann
    Division of Clinical Biochemistry and Immunology, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Leukemia 27:208-12. 2013
  3. ncbi request reprint Elimination of the need for urine studies in the screening algorithm for monoclonal gammopathies by using serum immunofixation and free light chain assays
    Jerry A Katzmann
    Division of Clinical Biochemistry and Immunology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
    Mayo Clin Proc 81:1575-8. 2006
  4. ncbi request reprint Diagnostic performance of quantitative kappa and lambda free light chain assays in clinical practice
    Jerry A Katzmann
    Division of Clinical Biochemistry and Immunology, Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Clin Chem 51:878-81. 2005
  5. pmc Disease associations with monoclonal gammopathy of undetermined significance: a population-based study of 17,398 patients
    John P Bida
    Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 84:685-93. 2009
  6. pmc Incidence of monoclonal gammopathy of undetermined significance and estimation of duration before first clinical recognition
    Terry M Therneau
    Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA
    Mayo Clin Proc 87:1071-9. 2012
  7. pmc Prevalence and risk of progression of light-chain monoclonal gammopathy of undetermined significance: a retrospective population-based cohort study
    Angela Dispenzieri
    Hematology, Mayo Clinic, Rochester, MN 55905, USA
    Lancet 375:1721-8. 2010
  8. pmc Long-term biological variation of serum protein electrophoresis M-spike, urine M-spike, and monoclonal serum free light chain quantification: implications for monitoring monoclonal gammopathies
    Jerry A Katzmann
    Division of Clinical Biochemistry and Immunology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Clin Chem 57:1687-92. 2011
  9. pmc Increased prevalence of light chain monoclonal gammopathy of undetermined significance (LC-MGUS) in first-degree relatives of individuals with multiple myeloma
    Alexandra J Greenberg
    Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, MN, USA
    Br J Haematol 157:472-5. 2012
  10. pmc Serum free light chain ratio is an independent risk factor for progression in monoclonal gammopathy of undetermined significance
    S Vincent Rajkumar
    Division of Hematology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Blood 106:812-7. 2005

Detail Information

Publications59

  1. ncbi request reprint Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains
    Jerry A Katzmann
    Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Clin Chem 48:1437-44. 2002
    ..These diseases are more prevalent in the elderly, and assays to detect and quantify abnormal amounts of FLCs require reference intervals that include elderly donors...
  2. pmc Suppression of uninvolved immunoglobulins defined by heavy/light chain pair suppression is a risk factor for progression of MGUS
    J A Katzmann
    Division of Clinical Biochemistry and Immunology, Department of Laboratory Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Leukemia 27:208-12. 2013
    ..8; 95% CI, 1.1-3.00; P=0.018). The finding that HLC-pair suppression predicts progression in MGUS and occurs several years before malignant transformation has implications for myeloma biology...
  3. ncbi request reprint Elimination of the need for urine studies in the screening algorithm for monoclonal gammopathies by using serum immunofixation and free light chain assays
    Jerry A Katzmann
    Division of Clinical Biochemistry and Immunology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
    Mayo Clin Proc 81:1575-8. 2006
    ..To determine the relative diagnostic contribution of urine assays as part of the screening algorithm for monoclonal gammopathies...
  4. ncbi request reprint Diagnostic performance of quantitative kappa and lambda free light chain assays in clinical practice
    Jerry A Katzmann
    Division of Clinical Biochemistry and Immunology, Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Clin Chem 51:878-81. 2005
    ..We evaluated its diagnostic performance in clinical practice...
  5. pmc Disease associations with monoclonal gammopathy of undetermined significance: a population-based study of 17,398 patients
    John P Bida
    Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 84:685-93. 2009
    ..To systematically study the association of monoclonal gammopathy of undetermined significance (MGUS) with all diseases in a population-based cohort of 17,398 patients, all of whom were uniformly tested for the presence or absence of MGUS...
  6. pmc Incidence of monoclonal gammopathy of undetermined significance and estimation of duration before first clinical recognition
    Terry M Therneau
    Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA
    Mayo Clin Proc 87:1071-9. 2012
    ..To determine the incidence of monoclonal gammopathy of undetermined significance (MGUS) in the general population and to estimate the duration of occult MGUS before first diagnosis...
  7. pmc Prevalence and risk of progression of light-chain monoclonal gammopathy of undetermined significance: a retrospective population-based cohort study
    Angela Dispenzieri
    Hematology, Mayo Clinic, Rochester, MN 55905, USA
    Lancet 375:1721-8. 2010
    ..The remaining 20% are characterised by absence of IgH expression; we aimed to assess prevalence of a corresponding precursor entity, light-chain MGUS...
  8. pmc Long-term biological variation of serum protein electrophoresis M-spike, urine M-spike, and monoclonal serum free light chain quantification: implications for monitoring monoclonal gammopathies
    Jerry A Katzmann
    Division of Clinical Biochemistry and Immunology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Clin Chem 57:1687-92. 2011
    ....
  9. pmc Increased prevalence of light chain monoclonal gammopathy of undetermined significance (LC-MGUS) in first-degree relatives of individuals with multiple myeloma
    Alexandra J Greenberg
    Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, MN, USA
    Br J Haematol 157:472-5. 2012
    ..We saw no increased risk in relatives of HC-MGUS probands. We conclude that the prevalence of LC-MGUS is significantly higher among 1° relatives of MM probands compared to the reference population...
  10. pmc Serum free light chain ratio is an independent risk factor for progression in monoclonal gammopathy of undetermined significance
    S Vincent Rajkumar
    Division of Hematology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Blood 106:812-7. 2005
    ....
  11. pmc Serum immunoglobulin free light-chain measurement in primary amyloidosis: prognostic value and correlations with clinical features
    Shaji Kumar
    Division of Hematology and Internal Medicine, Department of Laboratory Medicine and Pathology, Department of Biochemistry, Mayo Clinic, Rochester, MN, USA
    Blood 116:5126-9. 2010
    ..9 vs 37.1 months; P < .001. In multivariate analysis, dFLC was independent of other prognostic factors. The type of light chain impacts the spectrum of organ involvement and the FLC burden correlates with survival in AL...
  12. pmc Immunoglobulin free light chain ratio is an independent risk factor for progression of smoldering (asymptomatic) multiple myeloma
    Angela Dispenzieri
    Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
    Blood 111:785-9. 2008
    ..The serum immunoglobulin FLC ratio is an important additional determinant of clinical outcome in patients with SMM...
  13. pmc Screening panels for detection of monoclonal gammopathies
    Jerry A Katzmann
    Division of Clinical Biochemistry and Immunology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA
    Clin Chem 55:1517-22. 2009
    ..Although there are several reports on the relative diagnostic contribution of these assays, none has looked at the tests singly and in combination for the various plasma cell proliferative disorders (PCPDs)...
  14. pmc Serum immunoglobulin free light chain measurements and heavy chain isotype usage provide insight into disease biology in patients with POEMS syndrome
    Trista Stankowski-Drengler
    Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Am J Hematol 85:431-4. 2010
    ..In summary, serum immunoglobulin profiles are unique in POEMS syndrome as compared with other plasma cell disorders...
  15. ncbi request reprint Presence of monoclonal free light chains in the serum predicts risk of progression in monoclonal gammopathy of undetermined significance
    S Vincent Rajkumar
    Division of Hematology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Br J Haematol 127:308-10. 2004
    ..The presence of an abnormal kappa/lambda FLC ratio in the serum was associated with a higher risk of MGUS progression (relative risk 2.5; 95% confidence interval: 1.6-4.0; P < 0.001)...
  16. pmc Increased risk of monoclonal gammopathy in first-degree relatives of patients with multiple myeloma or monoclonal gammopathy of undetermined significance
    Celine M Vachon
    Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Blood 114:785-90. 2009
    ..0; 95% CI, 1.4 to 2.8) and MGUS probands (RR, 3.3; 95% CI, 2.1 to 4.8). The increased risk of MGUS in first-degree relatives of MGUS or MM patients implies shared environment and/or genetics...
  17. pmc Laboratory persistence and clinical progression of small monoclonal abnormalities
    David L Murray
    Division of Clinical Biochemistry and Immunology, Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Am J Clin Pathol 138:609-13. 2012
    ..This study demonstrates that in some patients with IFE MGUS, the M proteins are transient and that IgA IFE MGUS is more likely to persist and progress to myeloma...
  18. pmc Use of nonclonal serum immunoglobulin free light chains to predict overall survival in the general population
    Angela Dispenzieri
    Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 87:517-23. 2012
    ..To determine whether the free light chain (FLC) assay provides prognostic information relevant to the general population...
  19. pmc Monoclonal and polyclonal serum free light chains and clinical outcome in chronic lymphocytic leukemia
    Matthew J Maurer
    Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Blood 118:2821-6. 2011
    ..The FLC assay is a simple, widely available clinical test with similar prognostic utility as routinely used prognostic biomarkers for CLL. Among persons with FLC abnormalities, the type of abnormality affects prognostic significance...
  20. pmc Impact of optimal follow-up of monoclonal gammopathy of undetermined significance on early diagnosis and prevention of myeloma-related complications
    Giada Bianchi
    Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Blood 116:2019-25; quiz 2197. 2010
    ..Future studies are needed to replicate and expand our findings and to determine the optimal frequency of monitoring in higher-risk MGUS patients...
  21. doi request reprint Polyclonal immunoglobulin free light chain levels predict survival in myeloid neoplasms
    Animesh Pardanani
    Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 30:1087-94. 2012
    ..Because of immediate practical applicability, we chose plasma immunoglobulin free light chain (FLC) concentration as the biomarker of interest...
  22. pmc Elevated serum free light chains are associated with inferior event free and overall survival in Hodgkin lymphoma
    Carrie A Thompson
    Division of Hematology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Hematol 86:998-1000. 2011
    ..84; 95% CI: 1.84-12.7) and OS (HR = 8.87; 95% CI: 2.35-33.52) compared to patients with normal FLC. Further studies of FLC in HL are warranted...
  23. ncbi request reprint Prevalence of monoclonal gammopathy of undetermined significance
    Robert A Kyle
    Division of Hematology, Mayo Clinic, Rochester, Minn 55905, USA
    N Engl J Med 354:1362-9. 2006
    ..We used sensitive laboratory techniques to ascertain the prevalence of MGUS in a large population in a well-defined geographic area...
  24. pmc Immunoglobulin free light chains and solitary plasmacytoma of bone
    David Dingli
    Division of Hematology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Blood 108:1979-83. 2006
    ..5 g/dL) or higher (high risk, n = 18). The corresponding progression rates at 5 years were significantly different in the low, intermediate, and high groups: 13%, 26%, and 62%, respectively (P < .001)...
  25. pmc Absolute values of immunoglobulin free light chains are prognostic in patients with primary systemic amyloidosis undergoing peripheral blood stem cell transplantation
    Angela Dispenzieri
    Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN, USA
    Blood 107:3378-83. 2006
    ..Achievement of FLC response was a better predictor of survival than achievement of complete hematologic response or normalization of the FLC ratio. FLC measurements both before and after PBSCT are important predictors of patient outcome...
  26. ncbi request reprint Comparison of bromcresol green and agarose protein electrophoresis for quantitation of serum albumin in multiple myeloma
    Christine L H Snozek
    Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Clin Chem 53:1099-103. 2007
    ..Two common albumin assays, bromcresol green (BCG) and agarose gel protein electrophoresis (PEL), frequently yield discordant results, creating confusion regarding which assay is superior for use in myeloma...
  27. pmc Simultaneous phenotyping and quantification of α-1-antitrypsin by liquid chromatography-tandem mass spectrometry
    Yuhong Chen
    Division of Clinical Pharmacology, Department of Molecular and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA
    Clin Chem 57:1161-8. 2011
    ....
  28. doi request reprint Reference and interpretive ranges for α(1)-antitrypsin quantitation by phenotype in adult and pediatric populations
    Leslie J Donato
    Division of Clinical Biochemistry and Immunology, Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Am J Clin Pathol 138:398-405. 2012
    ..Other rare alleles, such as I, were also associated with decreased concentrations of A1AT, particularly in the context of a Z allele, and may warrant monitoring for symptoms of deficiency...
  29. pmc Elevated serum free light chains are associated with event-free and overall survival in two independent cohorts of patients with diffuse large B-cell lymphoma
    Matthew J Maurer
    Mayo Clinic College of Medicine and Mayo Foundation, Rochester, MN 55905, USA
    J Clin Oncol 29:1620-6. 2011
    ..This assay has prognostic value in plasma cell proliferative disorders. There are limited data on serum FLC in B-cell malignancies...
  30. ncbi request reprint Quantitation of serum monoclonal proteins: relationship between agarose gel electrophoresis and immunonephelometry
    David L Murray
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Clin Chem 55:1523-9. 2009
    ..Previous comparisons of monoclonal protein quantification identified a bias between serum protein electrophoresis (SPEP) and immunonephelometry (NEPH)...
  31. ncbi request reprint A comparison of morphologic features, flow cytometry, TCR-Vbeta analysis, and TCR-PCR in qualitative and quantitative assessment of peripheral blood involvement by Sézary syndrome
    William G Morice
    Division of Hematopathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Clin Pathol 125:364-74. 2006
    ....
  32. ncbi request reprint Serum-free light chain-a new biomarker for patients with B-cell non-Hodgkin lymphoma and chronic lymphocytic leukemia
    William Martin
    Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN, USA
    Transl Res 149:231-5. 2007
    ..Future studies are warranted to elucidate the role of serum FLC as biomarkers of disease, for monitoring of minimal residual disease, and as a prognostic factor for response and survival...
  33. pmc Appraisal of immunoglobulin free light chain as a marker of response
    Angela Dispenzieri
    Departments of Hematology, Mayo Clinic, Rochester, MN, USA
    Blood 111:4908-15. 2008
    ..Although baseline values of FLC are prognostic in newly diagnosed myeloma patients, serial measurements do not appear to have added value in patients who have M-proteins measurable by electrophoresis...
  34. ncbi request reprint Elevated serum monoclonal and polyclonal free light chains and interferon inducible protein-10 predicts inferior prognosis in untreated diffuse large B-cell lymphoma
    Thomas E Witzig
    Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota
    Am J Hematol 89:417-22. 2014
    ..These increased abnormal FLC and cytokines are potentially useful biomarkers for prognosis and selecting agents for untreated DLBCL...
  35. doi request reprint Using mass spectrometry to monitor monoclonal immunoglobulins in patients with a monoclonal gammopathy
    David R Barnidge
    Department of Laboratory Medicine and Pathology and Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota 55905, United States
    J Proteome Res 13:1419-27. 2014
    ..Our results show that microLC-ESI-Q-TOF MS provides superior sensitivity and specificity compared to conventional methods and shows promise as a viable method of detecting and isotyping an M-protein. ..
  36. pmc The utility of Lens culinaris agglutinin-reactive alpha-fetoprotein in the diagnosis of hepatocellular carcinoma: evaluation in a United States referral population
    Apinya Leerapun
    Miles and Shirley Fiterman Center for Digestive Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Clin Gastroenterol Hepatol 5:394-402; quiz 267. 2007
    ..We evaluated the utility of AFP-L3% for diagnosis of HCC in a US referral population...
  37. doi request reprint IgG4+ plasma cell infiltrates in liver explants with primary sclerosing cholangitis
    Lizhi Zhang
    Department of Laboratory Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 34:88-94. 2010
    ..PSC with tissue IgG4 positivity has a more aggressive clinical course manifested by shorter time to transplant and a higher likelihood of recurrence than IgG4 negative PSC...
  38. ncbi request reprint Elevated serum IgG4 concentration in patients with primary sclerosing cholangitis
    Flavia D Mendes
    Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Am J Gastroenterol 101:2070-5. 2006
    ..We sought to determine the frequency of elevated IgG4 in patients with PSC and to clinically compare PSC patients with elevated and normal IgG4 levels...
  39. pmc Alpha1-antitrypsin deficiency carriers, tobacco smoke, chronic obstructive pulmonary disease, and lung cancer risk
    Ping Yang
    Division of Epidemiology and Cancer Center, Mayo Clinic, Rochester, Minnesota 55905, USA
    Arch Intern Med 168:1097-103. 2008
    ..Genetic susceptibility in lung cancer risk has long been recognized but remains ill defined, as does the role of tobacco smoke exposure and chronic obstructive pulmonary disease (COPD)...
  40. ncbi request reprint Diagnosis of alpha-1-antitrypsin deficiency: An algorithm of quantification, genotyping, and phenotyping
    Melissa R Snyder
    Division of Clinical Biochemistry and Immunology, Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Clin Chem 52:2236-42. 2006
    ..The purpose of this study was to define and evaluate a strategy that provides reliable laboratory evaluation of A1AT deficiency...
  41. ncbi request reprint Gender differences in C-reactive protein concentrations-confirmation with two sensitive methods
    Joseph P McConnell
    Department of Laboratory, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Clin Chem Lab Med 40:56-9. 2002
    ..0001), was independent of age differences as assessed by multiple regression analysis. The observed gender differences have important implications for the establishment of cut-off points for cardiovascular risk stratification...
  42. ncbi request reprint Monitoring M-proteins in patients with multiple myeloma using heavy-chain variable region clonotypic peptides and LC-MS/MS
    David R Barnidge
    Department of Laboratory Medicine and Pathology, Department of Immunology, Department of Hematology, Mayo Clinic, Rochester, Minnesota 55905, United States
    J Proteome Res 13:1905-10. 2014
    ..Monitoring clonotypic peptides using SRM has the capacity to redefine clinical residual disease because of its superior sensitivity and specificity compared with current analytical methods. ..
  43. ncbi request reprint Urine protein electrophoresis and immunoelectrophoresis using unconcentrated or minimally concentrated urine samples
    Anja C Roden
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Am J Clin Pathol 130:141-5. 2008
    ..Testing unconcentrated urine specimens will mean fewer sample rejections owing to insufficient sample volume...
  44. pmc High prevalence of polyclonal hypergamma-globulinemia in adult males in Ghana, Africa
    Francis Buadi
    Division of Hematology, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Am J Hematol 86:554-8. 2011
    ..Future studies are needed to uncover genetic and environmental underpinnings of our finding, and to define the relationship between hypergamma-globulinemia, monoclonal gammopathy of undetermined significance (MGUS), and multiple myeloma...
  45. ncbi request reprint Flow cytometric assessment of TCR-Vbeta expression in the evaluation of peripheral blood involvement by T-cell lymphoproliferative disorders: a comparison with conventional T-cell immunophenotyping and molecular genetic techniques
    William G Morice
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Clin Pathol 121:373-83. 2004
    ..TCR-Vbeta flow cytometric analysis is a powerful clinical laboratory tool that can be used to aid in the rapid diagnosis of peripheral blood involvement by T-cell malignant neoplasms...
  46. ncbi request reprint Cerebrospinal fluid leakage: agarose gel electrophoresis detection of beta(2)-transferrin and nephelometric quantification of beta-trace protein
    Elizabeth L Sanders
    Division Clinical Biochemistry and Immunology, Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Clin Chem 50:2401-3. 2004
  47. ncbi request reprint Trimolecular complexes of lambda light chain dimers in serum of a patient with multiple myeloma
    Roshini S Abraham
    Division of Clinical Biochemistry and Immunology, Mayo Clinic, Scottsdale, AZ 85259, USA
    Clin Chem 48:1805-11. 2002
    ..Usually, these light chains exist as monomeric or dimeric forms, but rarely, larger molecules, such as tetramers, have been reported in the serum...
  48. ncbi request reprint Endometrial cancer: can nodal status be predicted with curettage?
    Andrea Mariani
    Section of Gynecologic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Gynecol Oncol 96:594-600. 2005
    ..To determine whether histologic or molecular markers assessed in pretreatment curettage specimens predict nodal metastasis in endometrial cancer...
  49. ncbi request reprint Molecular and histopathologic predictors of distant failure in endometrial cancer
    Andrea Mariani
    Department of Obstetrics and Gynecology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Cancer Detect Prev 27:434-41. 2003
    ..01). Thus, locoregional therapy may be insufficient when at least one of these predictors is present...
  50. ncbi request reprint Flow cytometric measurement of hemoglobin F in RBCs: diagnostic usefulness in the distinction of hereditary persistence of fetal hemoglobin (HPFH) and hemoglobin S-hPFH from other conditions with elevated levels of hemoglobin F
    James D Hoyer
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Clin Pathol 117:857-63. 2002
    ..Flow cytometry provides a more rapid and objective method for assessing cellular distribution of hemoglobin F and is useful for patient evaluation when HPFH trait, delta/beta-thalassemia trait, or hemoglobin S-HPFH trait is suspected...
  51. ncbi request reprint HER-2/neu overexpression and hormone dependency in endometrial cancer: analysis of cohort and review of literature
    Andrea Mariani
    Section of Gynecologic Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
    Anticancer Res 25:2921-7. 2005
    ..Overexpression of HER-2/neu (HER) is associated with unfavorable prognoses in both endometrial and breast cancer...
  52. ncbi request reprint Cerebrospinal fluid oligoclonal bands in the diagnosis of multiple sclerosis. Isoelectric focusing with IgG immunoblotting compared with high-resolution agarose gel electrophoresis and cerebrospinal fluid IgG index
    Alexandre S Fortini
    Departments of Laboratory Medicine and Pathology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Am J Clin Pathol 120:672-5. 2003
    ..The IEF method improves the sensitivity and the negative predictive value of the oligoclonal-banding assay, the IEF gels are easier to interpret, and the IEF assay requires a smaller cerebrospinal fluid volume...
  53. doi request reprint Clinical impact of discordance in serum albumin measurements on myeloma international staging system
    Prashant Kapoor
    J Clin Oncol 26:4051-2. 2008
  54. ncbi request reprint Prevalence of monoclonal gammopathy of undetermined significance among men in Ghana
    Ola Landgren
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Bldg EPS Room 7110, Bethesda, MD 20892 7236, USA
    Mayo Clin Proc 82:1468-73. 2007
    ....
  55. doi request reprint Screening algorithms for monoclonal gammopathies
    Jerry A Katzmann
    Clin Chem 54:1753-5. 2008
  56. ncbi request reprint Quantitative analysis of serum free light chains. A new marker for the diagnostic evaluation of primary systemic amyloidosis
    Roshini S Abraham
    Division of Clinical Biochemistry and Immunology, University of Birmingham, Birmingham, England
    Am J Clin Pathol 119:274-8. 2003
    ..In addition, the FLC assay can be used for follow-up of patients with amyloidosis who have undergone stem cell transplantation...
  57. doi request reprint Quantification of urinary light chains
    Melissa R Snyder
    Clin Chem 54:1744-6. 2008
  58. ncbi request reprint Serum free light chain specificity and sensitivity: a reality check
    Jerry A Katzmann
    Clin Chem 52:1638-9. 2006
  59. ncbi request reprint Correlation of serum immunoglobulin free light chain quantification with urinary Bence Jones protein in light chain myeloma
    Roshini S Abraham
    Clin Chem 48:655-7. 2002