Z S Katusic

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. ncbi request reprint Vascular endothelial dysfunction: does tetrahydrobiopterin play a role?
    Z S Katusic
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Physiol Heart Circ Physiol 281:H981-6. 2001
  2. ncbi request reprint Gene transfer of manganese superoxide dismutase reverses vascular dysfunction in the absence but not in the presence of atherosclerotic plaque
    M Zanetti
    Department of Endocrinology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Hum Gene Ther 12:1407-16. 2001
  3. ncbi request reprint Gene transfer of recombinant endothelial nitric oxide synthase to liver in vivo and in vitro
    V Shah
    Gastrointestinal Research Unit and Anesthesia Research Unit, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Physiol Gastrointest Liver Physiol 279:G1023-30. 2000
  4. ncbi request reprint Mechanisms of vascular instability in a transgenic mouse model of sickle cell disease
    K A Nath
    Nephrology, Mayo Clinic Foundation, Rochester, Minnesota 55905, USA
    Am J Physiol Regul Integr Comp Physiol 279:R1949-55. 2000
  5. ncbi request reprint Gene transfer of superoxide dismutase isoforms reverses endothelial dysfunction in diabetic rabbit aorta
    M Zanetti
    Department of Endocrinology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Am J Physiol Heart Circ Physiol 280:H2516-23. 2001
  6. ncbi request reprint Mechanism of endothelial dysfunction in apolipoprotein E-deficient mice
    L V d'Uscio
    Departments of Anesthesiology and Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Arterioscler Thromb Vasc Biol 21:1017-22. 2001
  7. ncbi request reprint Inhibitory effect of valves on endothelium-dependent relaxations to calcium ionophore in canine saphenous vein
    D Eguchi
    Departments of Anesthesiology and Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Physiol Heart Circ Physiol 280:H892-8. 2001
  8. ncbi request reprint Direct interaction between endothelial nitric-oxide synthase and dynamin-2. Implications for nitric-oxide synthase function
    S Cao
    GI Research Unit, Anesthesia Research and Department of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Biol Chem 276:14249-56. 2001
  9. pmc Oxidative stress and induction of heme oxygenase-1 in the kidney in sickle cell disease
    K A Nath
    Nephrology Research Unit, Mayo Clinic Foundation, 200 First St SW, 542 Guggenheim Bldg, Rochester, MN 55905, USA
    Am J Pathol 158:893-903. 2001
  10. ncbi request reprint Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells
    T A Baker
    Department of Anesthesiology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    J Cardiovasc Pharmacol 37:333-8. 2001

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Vascular endothelial dysfunction: does tetrahydrobiopterin play a role?
    Z S Katusic
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Physiol Heart Circ Physiol 281:H981-6. 2001
    ..In this review, the potential role of tetrahydrobiopterin in the pathogenesis of vascular endothelial dysfunction and mechanisms underlying beneficial vascular effects of tetrahydrobiopterin will be discussed...
  2. ncbi request reprint Gene transfer of manganese superoxide dismutase reverses vascular dysfunction in the absence but not in the presence of atherosclerotic plaque
    M Zanetti
    Department of Endocrinology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Hum Gene Ther 12:1407-16. 2001
    ..Adenovirus-mediated gene transfer of MnSOD to nonatherosclerotic carotid arteries, but not atherosclerotic aorta, normalizes EDVR. eNOS gene transfer improves EDVR, even in the presence of plaque...
  3. ncbi request reprint Gene transfer of recombinant endothelial nitric oxide synthase to liver in vivo and in vitro
    V Shah
    Gastrointestinal Research Unit and Anesthesia Research Unit, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Physiol Gastrointest Liver Physiol 279:G1023-30. 2000
    ..These events were associated with increased ionomycin-stimulated NO release. In summary, this is the first study to demonstrate successful delivery of the recombinant eNOS gene to liver in vivo and in vitro with ensuing NO production...
  4. ncbi request reprint Mechanisms of vascular instability in a transgenic mouse model of sickle cell disease
    K A Nath
    Nephrology, Mayo Clinic Foundation, Rochester, Minnesota 55905, USA
    Am J Physiol Regul Integr Comp Physiol 279:R1949-55. 2000
    ..Destabilization of the vasoactive balance in the sickle vasculature by clinically relevant states may predispose to vasoocclusive disease...
  5. ncbi request reprint Gene transfer of superoxide dismutase isoforms reverses endothelial dysfunction in diabetic rabbit aorta
    M Zanetti
    Department of Endocrinology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Am J Physiol Heart Circ Physiol 280:H2516-23. 2001
    ..Gene transfer of CuZn SOD and Mn SOD corrected both of these defects. Thus Ad-mediated gene transfer CuZn and Mn SOD to the diabetic aorta improves endothelium-dependent relaxation...
  6. ncbi request reprint Mechanism of endothelial dysfunction in apolipoprotein E-deficient mice
    L V d'Uscio
    Departments of Anesthesiology and Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Arterioscler Thromb Vasc Biol 21:1017-22. 2001
    ..Thus, chemical inactivation of NO with O(2)(-) and reduced biosynthesis of NO are key mechanisms responsible for endothelial dysfunction in aortas of atherosclerotic apoE-deficient mice...
  7. ncbi request reprint Inhibitory effect of valves on endothelium-dependent relaxations to calcium ionophore in canine saphenous vein
    D Eguchi
    Departments of Anesthesiology and Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Physiol Heart Circ Physiol 280:H892-8. 2001
    ..Lower production of nitric oxide in endothelial cells of valvular segments appears to be a mechanism responsible for reduced reactivity to A-23187...
  8. ncbi request reprint Direct interaction between endothelial nitric-oxide synthase and dynamin-2. Implications for nitric-oxide synthase function
    S Cao
    GI Research Unit, Anesthesia Research and Department of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Biol Chem 276:14249-56. 2001
    ..These events may have relevance for eNOS regulation and trafficking within vascular endothelium...
  9. pmc Oxidative stress and induction of heme oxygenase-1 in the kidney in sickle cell disease
    K A Nath
    Nephrology Research Unit, Mayo Clinic Foundation, 200 First St SW, 542 Guggenheim Bldg, Rochester, MN 55905, USA
    Am J Pathol 158:893-903. 2001
    ..Additionally, the oxidant-inducible, heme-degrading enzyme, HO-1, is induced regionally in the murine and human sickle kidney, and systemically, in circulating endothelial cells in sickle patients...
  10. ncbi request reprint Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells
    T A Baker
    Department of Anesthesiology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    J Cardiovasc Pharmacol 37:333-8. 2001
    ..This effect appears to be independent of the ability of vitamin C to scavenge superoxide anions...
  11. ncbi request reprint Gene transfer for cerebrovascular disease
    V G Khurana
    Department of Anesthesiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Curr Cardiol Rep 3:10-6. 2001
    ..Knowledge of the fundamental concepts of cerebrovascular gene transfer is therefore useful to understanding both its molecular basis and potential clinical utility...
  12. ncbi request reprint Thromboxane A2 receptor antagonists inhibit endothelium-dependent contractions
    W Auch Schwelk
    Department of Physiology and Biophysics, Mayo Clinic, Rochester, Minnesota
    Hypertension 15:699-703. 1990
    ..Oxygen-derived free radicals, which might be an endothelium-derived contracting factor or factors, ultimately cause contraction by stimulation of TXA2/PGH2 receptors...
  13. ncbi request reprint Protective effect of heme oxygenase-1 gene transfer against oxyhemoglobin-induced endothelial dysfunction
    D Eguchi
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Cereb Blood Flow Metab 21:1215-22. 2001
    ....
  14. ncbi request reprint Regulation of hepatic eNOS by caveolin and calmodulin after bile duct ligation in rats
    V Shah
    Gastrointestinal Research Unit, Mayo Clinic, Rochester, MN 55905, USA
    Am J Physiol Gastrointest Liver Physiol 280:G1209-16. 2001
    ..We conclude that, in cholestatic portal hypertension, caveolin may negatively regulate NOS activity in a manner that is reversible by excess calmodulin...
  15. ncbi request reprint Endothelial L-arginine pathway and regional cerebral arterial reactivity to vasopressin
    Z S Katusic
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905
    Am J Physiol 262:H1557-62. 1992
    ..This signal transduction pathway is not functional in endothelial cells of branches of middle cerebral arteries...
  16. ncbi request reprint Hypercholesterolemia impairs endothelium-dependent relaxations in common carotid arteries of apolipoprotein e-deficient mice
    L V d'Uscio
    Department of Anesthesiology, Mayo Clinic and Foundation, Rochester, Minnesota, USA
    Stroke 32:2658-64. 2001
    ..Our objective was to characterize the mechanisms underlying endothelial dysfunction in apoE-deficient mice...
  17. ncbi request reprint A direct mechanical method for accurate and efficient adenoviral vector delivery to tissues
    V G Khurana
    Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA
    Gene Ther 10:443-52. 2003
    ....
  18. pmc EPO tecting the endothelium
    T E Peterson
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Br J Pharmacol 150:823-5. 2007
    ....
  19. pmc Genetic deficiency of heme oxygenase-1 impairs functionality and form of an arteriovenous fistula in the mouse
    J P Juncos
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota 55905, USA
    Kidney Int 74:47-51. 2008
    ..We conclude that heme oxygenase-1 deficiency promotes vasculopathic gene expression, accelerates neointimal hyperplasia and impairs the function of arteriovenous fistulas...