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Genomes and Genes | Victor M KarpyakSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Genetic variability in the NMDA-dependent AMPA trafficking cascade is associated with alcohol dependenceVictor M Karpyak
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
Addict Biol 17:798-806. 2012..The statistically significant association of alcohol dependence with genetic variation in the NMDA-dependent AMPA receptor trafficking cascade indicates a need for further investigation of the role of this pathway in alcohol dependence...
Changes in heart rate variability in response to treatment with electroconvulsive therapyVictor M Karpyak
Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J ECT 20:81-8. 2004..Heart rate variability (HRV) has proven predictive value for patients with cardiac and neurologic disorders and correlates with depression severity and treatment effects. Variable changes in HRV after ECT have been reported...- Sequence variations of the human MPDZ gene and association with alcoholism in subjects with European ancestryVictor M Karpyak
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
Alcohol Clin Exp Res 33:712-21. 2009..Mpdz gene variations are known contributors of acute alcohol withdrawal severity and seizures in mice... 
Trazodone and alcohol relapse: a retrospective study following residential treatmentBhanu Prakash Kolla
Department of Psychiatry, Mayo Clinic, Rochester, Minnesota, USA
Am J Addict 20:525-9. 2011..Our retrospective study of a complex patient population discharged from a residential treatment setting did not find an association between trazodone use at discharge and relapse rates at 6 months...- Gender differences in the relationship between depressive symptoms and cravings in alcoholismNelli Boykoff
Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Am J Addict 19:352-6. 2010..78). Further prospective study is encouraged to evaluate whether depressive symptoms and concomitant alcohol cravings in women are a marker for relief cravings and, as such, a target symptom for treatment intervention... - Changes in heart rate variability associated with acute alcohol consumption: current knowledge and implications for practice and researchMagdalena Romanowicz
Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Alcohol Clin Exp Res 35:1092-105. 2011..Potential implications of this research include HRV response to alcohol that could serve as a marker for susceptibility to alcoholism. At present however there is almost no research data supporting this hypothesis... - Replication of genome wide association studies of alcohol dependence: support for association with variation in ADH1CJoanna M Biernacka
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, United States of America
PLoS ONE 8:e58798. 2013..Further studies should investigate the association of other polymorphisms in this gene with alcohol dependence and related alcohol-use phenotypes... - Functional role of the polymorphic 647 T/C variant of ENT1 (SLC29A1) and its association with alcohol withdrawal seizuresJeong Hyun Kim
Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
PLoS ONE 6:e16331. 2011..Interestingly, in humans, the ENT1 (SLC29A1) gene contains a non-synonymous single nucleotide polymorphism (647 T/C; rs45573936) that might be involved in the functional change of ENT1... - Utilization of residential alcoholism treatment in bipolar disorderDaniel K Hall-Flavin
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Addict 20:40-4. 2011..Future studies are encouraged to better understand utilization rates of addiction treatment among patients with bipolar disorder and to identify clinical correlates that predispose bipolar women to high-dose drinking. .. - Genome-wide gene-set analysis for identification of pathways associated with alcohol dependenceJoanna M Biernacka
Divisions of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
Int J Neuropsychopharmacol 16:271-8. 2013..These findings demonstrate the utility of GSA in the study of complex disease, and suggest specific directions for further research into the genetic architecture of alcohol dependence... - Interaction of SLC6A4 and DRD2 polymorphisms is associated with a history of delirium tremensVictor M Karpyak
Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Addict Biol 15:23-34. 2010..This study provides the first evidence to implicate the interaction between serotonin and dopamine neurotransmission in the etiology of DT. Replication is necessary to verify this potentially important finding... - Lack of effect of ECT on Holter monitor recordings before and after treatmentKeith G Rasmussen
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
J ECT 20:45-7. 2004..There has been concern about persisting cardiac effects of electroconvulsive therapy (ECT). Several studies have analyzed Holter monitor recordings before and after ECT, and generally have found no significant effects... - QTc dispersion in patients referred for electroconvulsive therapyM Leann Dodd
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
J ECT 24:131-3. 2008..To determine the presence of possible risk factors for arrhythmias during electroconvulsive therapy (ECT) by assessing QTc dispersion on the baseline electrocardiogram...