Victor M Karpyak

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. pmc PDYN rs2281285 variant association with drinking to avoid emotional or somatic discomfort
    Ulrich W Preuss
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany Department of Psychiatry, Martin Luther University, Halle Wittenberg, Germany
    PLoS ONE 8:e78688. 2013
  2. pmc Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states
    Victor M Karpyak
    Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Neuropsychopharmacol 16:975-85. 2013
  3. pmc Genetic variability in the NMDA-dependent AMPA trafficking cascade is associated with alcohol dependence
    Victor M Karpyak
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
    Addict Biol 17:798-806. 2012
  4. ncbi request reprint Changes in heart rate variability in response to treatment with electroconvulsive therapy
    Victor M Karpyak
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J ECT 20:81-8. 2004
  5. pmc Sequence variations of the human MPDZ gene and association with alcoholism in subjects with European ancestry
    Victor M Karpyak
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Alcohol Clin Exp Res 33:712-21. 2009
  6. doi request reprint Alcohol craving as a predictor of relapse
    Terry D Schneekloth
    Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Addict 21:S20-6. 2012
  7. pmc A retrospective study of gender differences in depressive symptoms and risk of relapse in patients with alcohol dependence
    Osama A Abulseoud
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55902, USA
    Am J Addict 22:437-42. 2013
  8. doi request reprint Trazodone and alcohol relapse: a retrospective study following residential treatment
    Bhanu Prakash Kolla
    Department of Psychiatry, Mayo Clinic, Rochester, Minnesota, USA
    Am J Addict 20:525-9. 2011
  9. pmc Association of GATA4 sequence variation with alcohol dependence
    Victor M Karpyak
    Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
    Addict Biol 19:312-5. 2014
  10. pmc Genome-wide gene-set analysis for identification of pathways associated with alcohol dependence
    Joanna M Biernacka
    Divisions of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
    Int J Neuropsychopharmacol 16:271-8. 2013

Collaborators

Detail Information

Publications20

  1. pmc PDYN rs2281285 variant association with drinking to avoid emotional or somatic discomfort
    Ulrich W Preuss
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany Department of Psychiatry, Martin Luther University, Halle Wittenberg, Germany
    PLoS ONE 8:e78688. 2013
    ..The aim of this study was to replicate a previously reported association of the PDYN rs2281285 variant with negative craving using a different phenotyping approach...
  2. pmc Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states
    Victor M Karpyak
    Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Neuropsychopharmacol 16:975-85. 2013
    ..These findings support the hypothesis that sequence variation in the PDYN gene contributes to both alcohol dependence and the induction of negative craving in alcohol-dependent subjects...
  3. pmc Genetic variability in the NMDA-dependent AMPA trafficking cascade is associated with alcohol dependence
    Victor M Karpyak
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
    Addict Biol 17:798-806. 2012
    ..The statistically significant association of alcohol dependence with genetic variation in the NMDA-dependent AMPA receptor trafficking cascade indicates a need for further investigation of the role of this pathway in alcohol dependence...
  4. ncbi request reprint Changes in heart rate variability in response to treatment with electroconvulsive therapy
    Victor M Karpyak
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J ECT 20:81-8. 2004
    ..Heart rate variability (HRV) has proven predictive value for patients with cardiac and neurologic disorders and correlates with depression severity and treatment effects. Variable changes in HRV after ECT have been reported...
  5. pmc Sequence variations of the human MPDZ gene and association with alcoholism in subjects with European ancestry
    Victor M Karpyak
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Alcohol Clin Exp Res 33:712-21. 2009
    ..Mpdz gene variations are known contributors of acute alcohol withdrawal severity and seizures in mice...
  6. doi request reprint Alcohol craving as a predictor of relapse
    Terry D Schneekloth
    Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Addict 21:S20-6. 2012
    ..This study evaluated craving intensity measured with the Penn Alcohol Craving Scale (PACS) at admission and discharge from residential treatment as a predictive factor of relapse after treatment...
  7. pmc A retrospective study of gender differences in depressive symptoms and risk of relapse in patients with alcohol dependence
    Osama A Abulseoud
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55902, USA
    Am J Addict 22:437-42. 2013
    ..The aim of this study was to investigate potential gender differences in situations associated with heavy alcohol drinking...
  8. doi request reprint Trazodone and alcohol relapse: a retrospective study following residential treatment
    Bhanu Prakash Kolla
    Department of Psychiatry, Mayo Clinic, Rochester, Minnesota, USA
    Am J Addict 20:525-9. 2011
    ..Our retrospective study of a complex patient population discharged from a residential treatment setting did not find an association between trazodone use at discharge and relapse rates at 6 months...
  9. pmc Association of GATA4 sequence variation with alcohol dependence
    Victor M Karpyak
    Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
    Addict Biol 19:312-5. 2014
    ..009) but no association with rs13273672. Further studies are needed to identify potential causal GATA4 variation(s) and the functional mechanism(s) contributing to this association. ..
  10. pmc Genome-wide gene-set analysis for identification of pathways associated with alcohol dependence
    Joanna M Biernacka
    Divisions of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
    Int J Neuropsychopharmacol 16:271-8. 2013
    ..These findings demonstrate the utility of GSA in the study of complex disease, and suggest specific directions for further research into the genetic architecture of alcohol dependence...
  11. ncbi request reprint Gender differences in the relationship between depressive symptoms and cravings in alcoholism
    Nelli Boykoff
    Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Am J Addict 19:352-6. 2010
    ..78). Further prospective study is encouraged to evaluate whether depressive symptoms and concomitant alcohol cravings in women are a marker for relief cravings and, as such, a target symptom for treatment intervention...
  12. pmc Functional role of the polymorphic 647 T/C variant of ENT1 (SLC29A1) and its association with alcohol withdrawal seizures
    Jeong Hyun Kim
    Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
    PLoS ONE 6:e16331. 2011
    ..Interestingly, in humans, the ENT1 (SLC29A1) gene contains a non-synonymous single nucleotide polymorphism (647 T/C; rs45573936) that might be involved in the functional change of ENT1...
  13. doi request reprint Interaction of SLC6A4 and DRD2 polymorphisms is associated with a history of delirium tremens
    Victor M Karpyak
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Addict Biol 15:23-34. 2010
    ..This study provides the first evidence to implicate the interaction between serotonin and dopamine neurotransmission in the etiology of DT. Replication is necessary to verify this potentially important finding...
  14. pmc Replication of genome wide association studies of alcohol dependence: support for association with variation in ADH1C
    Joanna M Biernacka
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, United States of America
    PLoS ONE 8:e58798. 2013
    ..Further studies should investigate the association of other polymorphisms in this gene with alcohol dependence and related alcohol-use phenotypes...
  15. doi request reprint Changes in heart rate variability associated with acute alcohol consumption: current knowledge and implications for practice and research
    Magdalena Romanowicz
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Alcohol Clin Exp Res 35:1092-105. 2011
    ..Potential implications of this research include HRV response to alcohol that could serve as a marker for susceptibility to alcoholism. At present however there is almost no research data supporting this hypothesis...
  16. doi request reprint Characteristics of heart rate variability in alcohol-dependent subjects and nondependent chronic alcohol users
    Victor M Karpyak
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, Minnesota
    Alcohol Clin Exp Res 38:9-26. 2014
    ..Future studies should investigate HRV as a biomarker of alcoholism development and treatment response as well as the physiological basis for alcohol effects on HRV. ..
  17. doi request reprint Utilization of residential alcoholism treatment in bipolar disorder
    Daniel K Hall-Flavin
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Addict 20:40-4. 2011
    ..Future studies are encouraged to better understand utilization rates of addiction treatment among patients with bipolar disorder and to identify clinical correlates that predispose bipolar women to high-dose drinking. ..
  18. pmc Treatment outcomes of depression: the pharmacogenomic research network antidepressant medication pharmacogenomic study
    David A Mrazek
    From the Departments of Psychiatry and Psychology, and Health Sciences Research, Mayo Clinic, Rochester, MN Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York Presbyterian Allen Hospital, New York, NY US Department of Defense, Department of Behavioral Health, Heidelberg, Germany Department of Psychiatry, Roy J and Lucille A Carver College of Medicine University of Iowa Hospitals and Clinics, Iowa, IA and Departments of Information Technology, and Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN
    J Clin Psychopharmacol 34:313-7. 2014
    ..The effectiveness of selective serotonin reuptake inhibitors (SSRIs) in patients with major depressive disorder (MDD) is controversial...
  19. ncbi request reprint Lack of effect of ECT on Holter monitor recordings before and after treatment
    Keith G Rasmussen
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J ECT 20:45-7. 2004
    ..There has been concern about persisting cardiac effects of electroconvulsive therapy (ECT). Several studies have analyzed Holter monitor recordings before and after ECT, and generally have found no significant effects...
  20. doi request reprint QTc dispersion in patients referred for electroconvulsive therapy
    M Leann Dodd
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    J ECT 24:131-3. 2008
    ..To determine the presence of possible risk factors for arrhythmias during electroconvulsive therapy (ECT) by assessing QTc dispersion on the baseline electrocardiogram...