Allan S Jaffe

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. ncbi request reprint Clinical characteristics and thrombolysis in myocardial infarction frame counts in women with transient left ventricular apical ballooning syndrome
    Kevin A Bybee
    Division of Cardiovascular Diseases and Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Am J Cardiol 94:343-6. 2004
  2. ncbi request reprint The quantification of infarct size
    Raymond J Gibbons
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
    J Am Coll Cardiol 44:1533-42. 2004
  3. ncbi request reprint Clinical importance of cardiac troponin release and cardiac abnormalities in patients with supratentorial cerebral hemorrhages
    Boby V Maramattom
    Department of Neurology and Division of Critical Care Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 81:192-6. 2006
  4. ncbi request reprint B-type natriuretic peptide in the assessment of acute lung injury and cardiogenic pulmonary edema
    Rimki Rana
    Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
    Crit Care Med 34:1941-6. 2006
  5. ncbi request reprint Cardiovascular biomarkers: the state of the art in 2006
    Allan S Jaffe
    Cardiology and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota 55905, United States
    Clin Chim Acta 381:9-13. 2007
  6. pmc Determinants and prognostic implications of cardiac troponin T measured by a sensitive assay in type 2 diabetes mellitus
    Jonas Hallén
    Department of Cardiology, Oslo University Hospital, Faculty of Medicine, University of Oslo, Oslo, Norway
    Cardiovasc Diabetol 9:52. 2010
  7. pmc A study to derive a clinical decision rule for triage of emergency department patients with chest pain: design and methodology
    Erik P Hess
    Department of Emergency Medicine, University of Ottawa, Ottawa, Canada
    BMC Emerg Med 8:3. 2008
  8. ncbi request reprint Prediction of medical morbidity and mortality after acute myocardial infarction in patients at increased psychosocial risk in the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) study
    Allan S Jaffe
    Cardiovascular Division, Mayo Clinic, Rochester, MN 55905, USA
    Am Heart J 152:126-35. 2006
  9. doi request reprint The clinical impact of the universal diagnosis of myocardial infarction
    Allan S Jaffe
    Mayo Clinic, Rochester, MN, USA
    Clin Chem Lab Med 46:1485-8. 2008
  10. doi request reprint Key issues in the developing synergism between cardiovascular imaging and biomarkers
    Allan S Jaffe
    Mayo Clinic and Medical School, Rochester, MN 55905, USA
    Clin Chem 54:1432-42. 2008

Detail Information

Publications110 found, 100 shown here

  1. ncbi request reprint Clinical characteristics and thrombolysis in myocardial infarction frame counts in women with transient left ventricular apical ballooning syndrome
    Kevin A Bybee
    Division of Cardiovascular Diseases and Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Am J Cardiol 94:343-6. 2004
    ..TIMI frame counts were abnormal in all patients and often abnormal in all 3 major coronary vessels, suggesting that the diffuse impairment of coronary microcirculatory function may play a role in the pathogenesis of the syndrome...
  2. ncbi request reprint The quantification of infarct size
    Raymond J Gibbons
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
    J Am Coll Cardiol 44:1533-42. 2004
    ..Therefore, SPECT sestamibi imaging is currently the best available technique for the quantitation of infarct size to assess the incremental treatment benefit of new therapies in multicenter trials of acute myocardial infarction...
  3. ncbi request reprint Clinical importance of cardiac troponin release and cardiac abnormalities in patients with supratentorial cerebral hemorrhages
    Boby V Maramattom
    Department of Neurology and Division of Critical Care Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 81:192-6. 2006
    ..To determine the Incidence of cardiac troponin T (cTnT) elevation, electrocardiographic (ECG) changes, and arrhythmias in supratentorial intracerebral hemorrhage (ICH) and their association with early mortality...
  4. ncbi request reprint B-type natriuretic peptide in the assessment of acute lung injury and cardiogenic pulmonary edema
    Rimki Rana
    Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
    Crit Care Med 34:1941-6. 2006
    ..We postulated that a low BNP level would exclude cardiac dysfunction as the principal cause of pulmonary edema and therefore help in the diagnosis of acute lung injury...
  5. ncbi request reprint Cardiovascular biomarkers: the state of the art in 2006
    Allan S Jaffe
    Cardiology and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota 55905, United States
    Clin Chim Acta 381:9-13. 2007
    ..These changes including greater sensitivity, a better understanding of what specific fragments are being measured and how these markers are used clinically is obligatory. There is also a need for new markers...
  6. pmc Determinants and prognostic implications of cardiac troponin T measured by a sensitive assay in type 2 diabetes mellitus
    Jonas Hallén
    Department of Cardiology, Oslo University Hospital, Faculty of Medicine, University of Oslo, Oslo, Norway
    Cardiovasc Diabetol 9:52. 2010
    ..Accordingly, we aimed to understand the prevalence, determinants, and prognostic implications of cardiac troponin T (cTnT) elevations measured with a high-sensitivity assay in patients with T2DM...
  7. pmc A study to derive a clinical decision rule for triage of emergency department patients with chest pain: design and methodology
    Erik P Hess
    Department of Emergency Medicine, University of Ottawa, Ottawa, Canada
    BMC Emerg Med 8:3. 2008
    ..Currently no methodologically robust clinical decision rule identifies patients safe for early discharge...
  8. ncbi request reprint Prediction of medical morbidity and mortality after acute myocardial infarction in patients at increased psychosocial risk in the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) study
    Allan S Jaffe
    Cardiovascular Division, Mayo Clinic, Rochester, MN 55905, USA
    Am Heart J 152:126-35. 2006
    ....
  9. doi request reprint The clinical impact of the universal diagnosis of myocardial infarction
    Allan S Jaffe
    Mayo Clinic, Rochester, MN, USA
    Clin Chem Lab Med 46:1485-8. 2008
    ..All of the recent guidelines now endorse the use of troponin as the biomarker or choice for the diagnosis of acute myocardial infarction (AMI)...
  10. doi request reprint Key issues in the developing synergism between cardiovascular imaging and biomarkers
    Allan S Jaffe
    Mayo Clinic and Medical School, Rochester, MN 55905, USA
    Clin Chem 54:1432-42. 2008
    ..The benefits of these state-of-the art imaging techniques can be enhanced by their use in combination with new cardiac biomarkers. This review addresses potentially useful interactions between imaging and biomarkers...
  11. ncbi request reprint Use of biomarkers in the emergency department and chest pain unit
    Allan S Jaffe
    Consultant in Cardiology and Laboratory Medicine Mayo Clinic and Mayo Medical School, Rochester, MN 55905, USA
    Cardiol Clin 23:453-65, vi. 2005
    ..Before describing the recommendations for clinical use of biomarkers in the ED, a basic understanding of some of the science and measurement issues related to these analytes is helpful...
  12. ncbi request reprint Biomarkers in acute cardiac disease: the present and the future
    Allan S Jaffe
    Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic and Medical School, Rochester, Minnesota 55905, USA
    J Am Coll Cardiol 48:1-11. 2006
    ..Finally, it reflects on some of the large number of markers that are still in development...
  13. doi request reprint Diseased skeletal muscle: a noncardiac source of increased circulating concentrations of cardiac troponin T
    Allan S Jaffe
    Core Clinical Laboratory Services Division, Department of Laboratory Medicine and Pathology, Mayo Clinic and Medical School, Rochester, Minnesota 55905, USA
    J Am Coll Cardiol 58:1819-24. 2011
    ..The purpose of this study was to determine whether there is immunoreactive cardiac troponin T (cTnT) expression in diseased skeletal muscle that might cause possible false-positive increases in cTnT...
  14. pmc Troponin T levels and infarct size by SPECT myocardial perfusion imaging
    Adelaide M Arruda-Olson
    Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    JACC Cardiovasc Imaging 4:523-33. 2011
    ....
  15. pmc Serial measurements of midregion proANP and copeptin in ambulatory patients with heart failure: incremental prognostic value of novel biomarkers in heart failure
    Wayne L Miller
    Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA
    Heart 98:389-94. 2012
    ....
  16. pmc Trends in incidence, severity, and outcome of hospitalized myocardial infarction
    Veronique L Roger
    MPH, Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Circulation 121:863-9. 2010
    ..In 2000, the definition of myocardial infarction (MI) changed to rely on troponin rather than creatine kinase (CK) and its MB fraction (CK-MB). The implications of this change on trends in MI incidence and outcome are not defined...
  17. ncbi request reprint Future biomarkers for detection of ischemia and risk stratification in acute coronary syndrome
    Fred S Apple
    Department of Laboratory Medicine and Pathology, Clinical Laboratories, Hennepin County Medical Center, Minneapolis, MN 55415, USA
    Clin Chem 51:810-24. 2005
    ....
  18. pmc Cardiac safety analysis of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab in the North Central Cancer Treatment Group N9831 adjuvant breast cancer trial
    Edith A Perez
    Division of Hematology Oncology, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224, USA
    J Clin Oncol 26:1231-8. 2008
    ..To assess cardiac safety and potential cardiac risk factors associated with trastuzumab in the NCCTG N9831 Intergroup adjuvant breast cancer trial...
  19. doi request reprint Only large reductions in concentrations of natriuretic peptides (BNP and NT-proBNP) are associated with improved outcome in ambulatory patients with chronic heart failure
    Wayne L Miller
    Cardiovascular Division, Mayo Medical Center, Rochester, MN, USA
    Clin Chem 55:78-84. 2009
    ..Large biologic variability, however, limits the usefulness of serial measurements in individual patients. As a result, the magnitude of change in peptide concentrations that is clinically meaningful remains to be established...
  20. ncbi request reprint The use of biomarkers for the evaluation and treatment of patients with acute coronary syndromes
    Amy K Saenger
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Gonda Building 5th floor, 200 First Street SW, Rochester, MN 55905, USA
    Med Clin North Am 91:657-81; xi. 2007
    ..This article discusses these issues, emphasizing what clinicians must know for optimal test use, and then addresses the practical use of these markers in patients who have ACS...
  21. pmc Thirty-day rehospitalizations after acute myocardial infarction: a cohort study
    Shannon M Dunlay
    Mayo Clinic, Rochester, MN 55905, USA
    Ann Intern Med 157:11-8. 2012
    ..Rehospitalization is a quality-of-care indicator, yet little is known about its occurrence and predictors after myocardial infarction (MI) in the community...
  22. ncbi request reprint Prognostication of survival using cardiac troponins and N-terminal pro-brain natriuretic peptide in patients with primary systemic amyloidosis undergoing peripheral blood stem cell transplantation
    Angela Dispenzieri
    Division of Hematology and Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Blood 104:1881-7. 2004
    ..Using this system, 49%, 38%, and 13% of patients were in stage I, stage II, and stage III, respectively. Determining levels of circulating biomarkers may be the most powerful tool for staging patients with AL undergoing PBSCT...
  23. doi request reprint Association of hyponatremia and elevated copeptin with death and need for transplantation in ambulatory patients with chronic heart failure
    Wayne L Miller
    Division of Cardiovascular Diseases, Mayo Clinic and Foundation, Rochester, MN, USA
    Am J Cardiol 111:880-5. 2013
    ..A strategy of serial monitoring of copeptin in combination with hyponatremia may be valuable in identifying higher risk patients with heart failure...
  24. ncbi request reprint Baseline troponin level: key to understanding the importance of post-PCI troponin elevations
    Wayne L Miller
    Cardiovascular Division, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Eur Heart J 27:1061-9. 2006
    ....
  25. ncbi request reprint Lower rather than higher levels of B-type natriuretic peptides (NT-pro-BNP and BNP) predict short-term mortality in end-stage heart failure patients treated with nesiritide
    Wayne L Miller
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA
    Am J Cardiol 96:837-41. 2005
    ..These findings suggest that the natriuretic peptide system can no longer contribute adequately to neurohormonal compensation and that paradoxically low peptide levels are an adverse prognostic marker in advanced HF...
  26. ncbi request reprint Serial biomarker measurements in ambulatory patients with chronic heart failure: the importance of change over time
    Wayne L Miller
    Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Circulation 116:249-57. 2007
    ..To determine if there are advantages to serial measurements, we evaluated stable chronic heart failure patients every 3 months for 2 years...
  27. doi request reprint Long-term prognostic significance of elevated cardiac troponin levels in critically ill patients with acute gastrointestinal bleeding
    Vlad C Vasile
    Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
    Crit Care Med 37:140-7. 2009
    ..However, there are no data addressing the independent association of troponin levels and mortality, adjusted for the severity of the underlying disease, in patients with GI bleeding...
  28. pmc Left ventricular function and C-reactive protein levels in acute myocardial infarction
    Adelaide M Arruda-Olson
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Am J Cardiol 105:917-21. 2010
    ..This suggests that inflammation is related to the ventricular remodeling processes, independently of LV systolic function...
  29. doi request reprint Cardiac function and brain-type natriuretic peptide in first-time flash pulmonary edema
    Jacob P Dal-Bianco
    Division of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Mayo Clin Proc 83:289-96. 2008
    ..To assess left ventricular (LV) function and brain-type natriuretic peptide (BNP) in patients with first-time flash pulmonary edema (FPE)...
  30. ncbi request reprint Troponin, B-type natriuretic peptides and outcomes in severe heart failure: differences between ischemic and dilated cardiomyopathies
    Wayne L Miller
    Division of Cardiovascular Diseases, Biochemistry and Immunology, Mayo Clinic, Rochester, MN 55905, USA
    Clin Cardiol 30:245-50. 2007
    ..Accordingly, we compared these biomarkers in patients with chronic HF...
  31. ncbi request reprint Serum cardiac troponins and N-terminal pro-brain natriuretic peptide: a staging system for primary systemic amyloidosis
    Angela Dispenzieri
    Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 22:3751-7. 2004
    ..Others have reported that N-terminal pro-brain natriuretic peptide (NT-proBNP) is a valuable prognostic marker. We sought to develop a staging system for patients with AL...
  32. doi request reprint Significance of elevated cardiac troponin T levels in critically ill patients with acute respiratory disease
    Vlad C Vasile
    Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
    Am J Med 123:1049-58. 2010
    ..After adjusting for the severity of disease measured by the Acute Physiology, Age, and Chronic Health Evaluation (APACHE) III prognostic system, we evaluated short-term (30 days) and long-term (3 years) mortality...
  33. doi request reprint Response of novel biomarkers to BNP infusion in patients with decompensated heart failure: a multimarker paradigm
    Wayne L Miller
    Mayo Clinic, Rochester, MN 55905, USA
    J Cardiovasc Transl Res 2:526-35. 2009
    ..These results are hypothesis generating to stimulate additional investigation...
  34. ncbi request reprint Long-term prognosis of patients with clinical unstable angina pectoris without elevation of creatine kinase but with elevation of cardiac troponin i levels
    Ronnier J Aviles
    Division of Cardiovascular Medicine, The Mayo Medical School, Rochester, Minnesota 55905, USA
    Am J Cardiol 90:875-8. 2002
  35. ncbi request reprint Quality specifications for B-type natriuretic peptide assays
    Fred S Apple
    Department of Laboratory Medicine and Pathology, Hennepin County Medical Center, Minneapolis, MN 55415, USA
    Clin Chem 51:486-93. 2005
    ....
  36. ncbi request reprint Biomarker responses during and after treatment with nesiritide infusion in patients with decompensated chronic heart failure
    Wayne L Miller
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic Rochester, MN 55905, USA
    Clin Chem 51:569-77. 2005
    ..Serial measurements of biomarkers might be beneficial. Therapy guided by N-terminal pro-B-type natriuretic peptide (NT-proBNP) might be helpful because NT-proBNP should be lowered by therapies that decrease endogenous BNP secretion...
  37. doi request reprint Aborted myocardial infarction: is it real in the troponin era?
    Vlad C Vasile
    Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
    Am Heart J 157:636-41. 2009
    ....
  38. ncbi request reprint Redefinition of myocardial infarction: prospective evaluation in the community
    Veronique L Roger
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
    Circulation 114:790-7. 2006
    ..The use of troponins will increase the detection of MI by a magnitude to be quantified, and the clinical acceptance of the new definition is unknown...
  39. doi request reprint Significance of periprocedural myonecrosis on outcomes after percutaneous coronary intervention: an analysis of preintervention and postintervention troponin T levels in 5487 patients
    Abhiram Prasad
    Department of Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minn, USA
    Circ Cardiovasc Interv 1:10-9. 2008
    ..The aim of this study was to evaluate the relative impact of preprocedural and postprocedural cardiac troponin T (cTnT) levels on survival rate after PCI...
  40. doi request reprint Defining high-sensitivity cardiac troponin concentrations in the community
    Paul M McKie
    Cardiorenal Research Laboratory, Mayo Clinic and Foundation, Rochester, MN 55902, USA
    Clin Chem 59:1099-107. 2013
    ..Therefore, our objective was to define hs-cTnI reference values and determinants in the general community, in a healthy reference cohort, and in subsets with diseases...
  41. pmc Prognostic value of cardiac troponin T after myocardial infarction: a contemporary community experience
    Yariv Gerber
    Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Mayo Clin Proc 87:247-54. 2012
    ..To evaluate the role of cardiac troponin T (cTnT) in predicting death, recurrent ischemic events, and heart failure among community-dwelling persons with first myocardial infarction (MI)...
  42. doi request reprint Profiles of serial changes in cardiac troponin T concentrations and outcome in ambulatory patients with chronic heart failure
    Wayne L Miller
    Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA
    J Am Coll Cardiol 54:1715-21. 2009
    ..The purpose of this study was to determine whether different profiles of cardiac troponin T (cTnT) values assessed over time would yield incremental prognostic information on clinically stable outpatients with heart failure (HF)...
  43. pmc Left ventricular function and heart failure in myocardial infarction: impact of the new definition in the community
    Adelaide M Arruda-Olson
    Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Am Heart J 156:810-5. 2008
    ....
  44. ncbi request reprint Lipoprotein-associated phospholipase A2 and prognosis after myocardial infarction in the community
    Yariv Gerber
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
    Arterioscler Thromb Vasc Biol 26:2517-22. 2006
    ..We evaluated the role of lipoprotein-associated phospholipase A2 (Lp-PLA2), an inflammatory biomarker, in defining risk after myocardial infarction (MI)...
  45. ncbi request reprint Survival in patients with primary systemic amyloidosis and raised serum cardiac troponins
    Angela Dispenzieri
    Division of Haematology and Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Lancet 361:1787-9. 2003
    ..024 microg/L, less than 0.01 microg/L, and 0.084 microg/L, and for cTnI were 0.1 microg/L, 0.05 microg/L, and 0.24 microg/L, respectively. After multivariate analysis, cTnT proved a better predictor of survival than cTnI...
  46. ncbi request reprint Excess weight at time of presentation of myocardial infarction is associated with lower initial mortality risks but higher long-term risks including recurrent re-infarction and cardiac death
    Anil Nigam
    Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    Int J Cardiol 110:153-9. 2006
    ..To evaluate the influence of elevated body mass index (BMI) on short- and long-term survival following acute myocardial infarction (AMI)...
  47. ncbi request reprint Troponin elevation in severe sepsis and septic shock: the role of left ventricular diastolic dysfunction and right ventricular dilatation*
    Giora Landesberg
    1Division of Anesthesiology and Critical Care Medicine, Hadassah University Medical Center, Jerusalem, Israel 2The Cardiovascular Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 3Division of Cardiology, Hadassah Hebrew University Medical Center, Jerusalem, Israel 4The Bio Medical Engineering, The Technion, Haifa, Israel
    Crit Care Med 42:790-800. 2014
    ..We hypothesized that detailed investigation of myocardial dysfunction by echocardiography can provide insight into the possible causes of troponin elevation and its association with mortality in sepsis...
  48. ncbi request reprint National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine Practice Guidelines: analytical issues for biomarkers of heart failure
    Fred S Apple
    Hennepin County Medical Center, Minneapolis, MN, USA
    Clin Biochem 41:222-6. 2008
  49. doi request reprint Pediatric brain natriuretic peptide concentrations vary with age and sex and appear to be modulated by testosterone
    Amy K Saenger
    Department of Laboratory Medicine and Pathology Division of Clinical Core Laboratory Services, Mayo Clinic, Rochester, MN 55905, USA
    Clin Chem 55:1869-75. 2009
    ..Children/adolescents typically have rapid hormone changes during puberty, making them an ideal group to study...
  50. ncbi request reprint Timing of peak troponin T and creatine kinase-MB elevations after percutaneous coronary intervention
    Wayne L Miller
    Cardiovascular Division, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Chest 125:275-80. 2004
    ..However, the time to peak biomarker appearance in the circulation has not been defined and is the purpose of this pilot study...
  51. doi request reprint Troponin elevations after electroconvulsive therapy: the need for caution
    Matthew W Martinez
    Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minn, USA
    Am J Med 124:229-34. 2011
    ..Troponin elevations are associated with an adverse prognosis, and it is well known that central nervous system insults can cause biochemical evidence of cardiac injury. No study previously has studied this with electroconvulsive therapy...
  52. doi request reprint Role for precursor Pro-B type natriuretic peptide in assessing response to therapy and prognosis in patients with decompensated heart failure treated with nesiritide
    Wayne L Miller
    Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic, Rochester, MN 55905, United States
    Clin Chim Acta 406:119-23. 2009
    ..This heterogeneity may confound interpretation of NP concentrations. The aim of this study was to evaluate the response to therapy and prognostic influence of proBNP in a cohort of patients admitted to hospital for decompensated HF...
  53. pmc Plasma lipoprotein-associated phospholipase A2 levels in heart failure: association with mortality in the community
    Yariv Gerber
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, United States
    Atherosclerosis 203:593-8. 2009
    ..We evaluated the association of Lp-PLA2 with mortality in subjects with HF and assessed its incremental value for risk discrimination over established risk factors and biomarkers...
  54. ncbi request reprint B-type natriuretic peptide clinical activation in aortic stenosis: impact on long-term survival
    Marie Annick Clavel
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota
    J Am Coll Cardiol 63:2016-25. 2014
    ..This study was conducted to define the association between serum B-type natriuretic peptide (BNP) activation and survival after the diagnosis of aortic stenosis (AS)...
  55. doi request reprint BD rapid serum tubes reduce false positive plasma troponin T results on the Roche Cobas e411 analyzer
    Christopher D Koch
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester MN 55905, USA
    Clin Biochem 45:842-4. 2012
    ..In an attempt to reduce false positive results and improve turnaround time, we investigated the BD Rapid Serum Tube as an alternate sample type to lithium heparin plasma for Roche Troponin T analysis on the Roche Cobas e411 analyzer...
  56. doi request reprint Development of a clinical prediction rule for 30-day cardiac events in emergency department patients with chest pain and possible acute coronary syndrome
    Erik P Hess
    Department of Emergency Medicine, Division of Emergency Medicine Research, Mayo Clinic College of Medicine, Rochester, MN, USA
    Ann Emerg Med 59:115-25.e1. 2012
    ..We seek to identify patients at low short-term risk for a cardiac event for whom additional ED investigations might be unnecessary...
  57. doi request reprint Elevated cardiac troponin is an independent risk factor for short- and long-term mortality in medical intensive care unit patients
    Luciano Babuin
    Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
    Crit Care Med 36:759-65. 2008
    ..Troponin elevations are common in critically ill patients. Whether they are predictors of mortality independent of the severity of the underlying disease is unclear...
  58. pmc Troponin: the biomarker of choice for the detection of cardiac injury
    Luciano Babuin
    Cardiovascular Division, Mayo Clinic and Mayo Clinic Graduate Medical School, Rochester, Minn 55905, USA
    CMAJ 173:1191-202. 2005
    ..In this review, we discuss the science underlying the use of troponin biomarkers, how to interpret troponin values properly and how to apply these measurements to patients who present with possible cardiovascular disease...
  59. ncbi request reprint Elevated donor troponin levels are associated with a lower frequency of allograft vasculopathy
    Wayne L Miller
    Mayo Medical Center, Rochester, Minnesota, USA
    J Heart Lung Transplant 24:2075-8. 2005
    ..Elevated troponin levels in the donor serum might provide a marker for this phenomenon; therefore, we evaluated the relationship of donor troponin levels to the development of CAV...
  60. ncbi request reprint Regional systems of care to optimize timeliness of reperfusion therapy for ST-elevation myocardial infarction: the Mayo Clinic STEMI Protocol
    Henry H Ting
    MBA, Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN 55905
    Circulation 116:729-36. 2007
    ..We implemented and evaluated a protocol to optimize the timeliness of reperfusion therapy and to coordinate systems of care for a PCI center and 28 regional hospitals located up to 150 miles away across 3 states...
  61. doi request reprint Elevated cardiac troponin T levels in critically ill patients with sepsis
    Vlad C Vasile
    Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, Minn Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minn
    Am J Med 126:1114-21. 2013
    ....
  62. doi request reprint Myocarditis with ST elevation and elevated cardiac enzymes misdiagnosed as an ST-elevation myocardial infarction
    Seth H Sheldon
    Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Emerg Med 43:996-9. 2012
    ..Quickly determining the correct diagnosis is critical given the "time is muscle" implication with a STEMI and the potential adverse effects associated with use of fibrinolytic therapy...
  63. ncbi request reprint Acute myocardial infarction and renal dysfunction: a high-risk combination
    R Scott Wright
    Division of Cardiology, Mayo Alliance for Clinical Trials, Mayo Clinic, Stabile 5, 150 Third Street SW, Rochester, MN 55902, USA
    Ann Intern Med 137:563-70. 2002
    ..Survival is poor in patients with acute myocardial infarction (MI) who also have severe renal disease. Less is known about the outcome of acute MI in patients with mild to moderate renal insufficiency...
  64. ncbi request reprint Cardiac troponin T in obstructive sleep apnea
    Apoor S Gami
    Division of Cardiovascular Diseases, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Chest 125:2097-100. 2004
    ..We tested the hypothesis that severe nocturnal hypoxia in patients with OSA causes myocyte necrosis as evidenced by increases in cardiac troponin T...
  65. ncbi request reprint Relation of ADRB1, CYP2D6, and UGT1A1 polymorphisms with dose of, and response to, carvedilol or metoprolol therapy in patients with chronic heart failure
    Linnea M Baudhuin
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA
    Am J Cardiol 106:402-8. 2010
    ..The ADRB1 and CYP2D6 genotype, alone and in haplotype, were significantly associated with the dose of carvedilol...
  66. ncbi request reprint European Society of Cardiology and American College of Cardiology guidelines for redefinition of myocardial infarction: how to use existing assays clinically and for clinical trials
    Fred S Apple
    Department of Laboratory Medicine and Pathology, Hennepin County Medical Center and University of Minnesota School of Medicine, Minneapolis, Minn, USA
    Am Heart J 144:981-6. 2002
    ..The Clinical Outcomes Utilizing Revascularization and Aggressive druG Evaluation (COURAGE) trial asked for recommendations concerning the use of troponin assays for the trial...
  67. doi request reprint Catecholamine interference in enzymatic creatinine assays
    Amy K Saenger
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Clin Chem 55:1732-6. 2009
    ..Negative interferences with the enzymatic creatinine assay, which we noted in several patients on dopamine or dobutamine, prompted our further investigation into interference of catecholamines with enzymatic methods...
  68. doi request reprint Comparison of mass spectrometry and clinical assay measurements of circulating fragments of B-type natriuretic peptide in patients with chronic heart failure
    Wayne L Miller
    Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Circ Heart Fail 4:355-60. 2011
    ..The purpose of the study was to relate clinically available BNP values with quantitative information on the concentration of pre-secretion and post-processed fragments of BNP detected by mass spectrometry...
  69. doi request reprint Aspirin responsiveness in healthy volunteers measured with multiple assay platforms
    Brad S Karon
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
    Clin Chem 54:1060-5. 2008
    ..We evaluated the sensitivity, precision, and concordance of 4 assays designed to detect aspirin responsiveness or resistance...
  70. pmc Decision support tool for early differential diagnosis of acute lung injury and cardiogenic pulmonary edema in medical critically ill patients
    Christopher N Schmickl
    Multidisciplinary Epidemiology and Translational Research in Intensive Care METRIC, Mayo Clinic, Rochester, MN, USA
    Chest 141:43-50. 2012
    ..No single clinical parameter provides satisfying prediction. We hypothesized that a combination of those will facilitate early differential diagnosis...
  71. doi request reprint Assessment of clinical performance without adequate analytical validation: A prescription for confusion
    Lawrence K Oliver
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Clin Biochem 44:1247-52. 2011
    ..Lp-PLA2 is a biomarker with promise for predicting cardiac risk. The lack of reproducible results has limited its use. In evaluating a new reagent kit, we investigated conditions for optimal reproducibility...
  72. doi request reprint Biological and analytical variability of a novel high-sensitivity cardiac troponin T assay
    Vlad C Vasile
    Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic and Mayo Medical School, Rochester, MN 55905, USA
    Clin Chem 56:1086-90. 2010
    ..We assessed short- and long-term biological variability of cardiac troponin T (cTnT) in healthy subjects with a novel high-sensitivity (hs) assay...
  73. ncbi request reprint Usefulness of brain natriuretic peptide levels in the clinical evaluation of patients with hypertrophic cardiomyopathy
    Josepha Binder
    Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Am J Cardiol 100:712-4. 2007
    ....
  74. pmc Weight change after myocardial infarction--the Enhancing Recovery in Coronary Heart Disease patients (ENRICHD) experience
    Francisco Lopez-Jimenez
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine and Mayo Clinic Foundation, Rochester, MN, USA
    Am Heart J 155:478-84. 2008
    ..The relationship of changes in weight to outcomes in patients after myocardial infarction (MI) is controversial...
  75. ncbi request reprint Lack of association between worsening renal function and mortality in heart failure patients treated with nesiritide
    Wayne L Miller
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, United States
    Int J Cardiol 126:234-9. 2008
    ..Because nesiritide may exacerbate renal dysfunction, it has been claimed that there may be a link between worsening renal function caused by nesiritide and increased mortality...
  76. ncbi request reprint Diagnostic accuracy of clinical prediction rules to exclude acute coronary syndrome in the emergency department setting: a systematic review
    Erik P Hess
    Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario
    CJEM 10:373-82. 2008
    ..We sought to determine the diagnostic accuracy of clinical prediction rules to exclude acute coronary syndrome (ACS) in the emergency department (ED) setting...
  77. ncbi request reprint Effect of doxorubicin plus cyclophosphamide on left ventricular ejection fraction in patients with breast cancer in the North Central Cancer Treatment Group N9831 Intergroup Adjuvant Trial
    Edith A Perez
    North Central Cancer Treatment Group, Division of Hematology Oncology, Mayo Clinic, Jacksonville, FL 32224, USA
    J Clin Oncol 22:3700-4. 2004
    ....
  78. ncbi request reprint B-type natriuretic peptides in heart failure: update on clinical applications and limitations
    Wayne L Miller
    Mayo Clinic, Divisions of Cardiovascular Diseases, College of Medicine and Foundation, 200 First Street, SW, Rochester, MN 55905, USA
    Biomark Med 1:503-12. 2007
    ..Like any clinical test, the usefulness of natriuretic peptides measurements depends upon appropriate use and recognition of limitations. This review focuses on these issues...
  79. ncbi request reprint Gender differences in C-reactive protein concentrations-confirmation with two sensitive methods
    Joseph P McConnell
    Department of Laboratory, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Clin Chem Lab Med 40:56-9. 2002
    ..0001), was independent of age differences as assessed by multiple regression analysis. The observed gender differences have important implications for the establishment of cut-off points for cardiovascular risk stratification...
  80. ncbi request reprint Reduced risks of death and CHF are associated with statin therapy administered acutely within the first 24 h of AMI
    R Scott Wright
    Division of Cardiology, Department of Internal Medicine, USA
    Int J Cardiol 108:314-9. 2006
    ..There are little data about whether early statin therapy reduces risk of CHF and alters timing of death...
  81. ncbi request reprint Clinical cues for detecting ictal asystole
    Gena R Ghearing
    Dept of Neurology, Mayo Clinic Rochester, Rochester, MN 55905, USA
    Clin Auton Res 17:221-6. 2007
    ..Recognition of ictal asystole is important as treatment with both antiepileptic drugs and cardiac pacing may be necessary. The purpose of this study was to identify clinical cues to aid in the detection of ictal asystole...
  82. ncbi request reprint Intracardiac thrombosis and embolism in patients with cardiac amyloidosis
    DaLi Feng
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Circulation 116:2420-6. 2007
    ..Furthermore, the clinical and echocardiographic variables that may be associated with thromboembolism in cardiac amyloidosis have not been defined...
  83. ncbi request reprint Elevations of troponin in patients with epileptic seizures? What do they mean?
    Simona Parvulescu-Codrea
    Department of Neurology, Division of Epilepsy, Mayo Clinic, Rochester, Minnesota 55905, USA
    Clin Cardiol 29:325-6. 2006
    ..Elevations of troponin should not be considered to be due to isolated seizures. This case illustrates the importance of having data concerning the response of troponin in various emergency and clinical situations...
  84. ncbi request reprint Elevations of cardiac troponin I are associated with increased short-term mortality in noncardiac critically ill emergency department patients
    R Scott Wright
    Division of Cardiology, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota, USA
    Am J Cardiol 90:634-6. 2002
  85. ncbi request reprint Cardiac amyloidosis presenting with elevations of cardiac troponin I and angina pectoris
    Ryan V Cantwell
    Mayo Clinic and Foundation, Department of Internal Medicine, Rochester, Minnesota 55905, USA
    Clin Cardiol 25:33-7. 2002
    ..The electron microscopy in our case confirms cardiac damage as the mechanism for cTnI elevation. This observation strengthens our knowledge about the specificity of cTnI for the detection of cardiac injury...
  86. ncbi request reprint 60-year-old man with chest pain
    Apoor S Gami
    Mayo Graduate School, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
    Mayo Clin Proc 79:399-402. 2004
  87. ncbi request reprint Lipoprotein-associated phospholipase A2: review and recommendation of a clinical cut point for adults
    Richard B Lanman
    diaDexus, Inc, South San Francisco, CA 94080, USA
    Prev Cardiol 9:138-43. 2006
    ....
  88. ncbi request reprint [Using troponins in the correct way]
    Luciano Babuin
    G Ital Cardiol (Rome) 8:382-4. 2007
  89. ncbi request reprint Health outcomes categorized by current and previous definitions of acute myocardial infarction in an unselected cohort of troponin-naïve emergency department patients
    Peter A Kavsak
    Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada, and Department of Pathology, Women and Infants Hospital of Rhode Island, Providence, USA
    Clin Chem 52:2028-35. 2006
    ..The health outcomes were based on the WHO definition and occurred in an era that preceded the use of cardiac troponin biomarkers...
  90. ncbi request reprint Letter regarding article by Khan et al, "prognostic value of troponin T and I among asymptomatic patients with end-stage renal disease: a meta-analysis"
    Fred S Apple
    Circulation 113:e775; author reply e776. 2006
  91. ncbi request reprint The impact of the ESC/ACC redefinition of myocardial infarction and new sensitive troponin assays on the frequency of acute myocardial infarction
    Peter A Kavsak
    Research Institute at Lakeridge Health, Oshawa, Ontario, Canada
    Am Heart J 152:118-25. 2006
    ....
  92. doi request reprint Cross-reactivity of BNP, NT-proBNP, and proBNP in commercial BNP and NT-proBNP assays: preliminary observations from the IFCC Committee for Standardization of Markers of Cardiac Damage
    Kristin N Luckenbill
    Clin Chem 54:619-21. 2008
  93. ncbi request reprint Long-term health outcomes associated with detectable troponin I concentrations
    Peter A Kavsak
    Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada
    Clin Chem 53:220-7. 2007
    ..We designed this study to extend this observation by examining risk prediction in both men and women presenting to an emergency department with chest discomfort...
  94. ncbi request reprint Effects of contemporary troponin assay sensitivity on the utility of the early markers myoglobin and CKMB isoforms in evaluating patients with possible acute myocardial infarction
    Peter A Kavsak
    Department of Pathology and Molecular Medicine, McMaster University Medical Centre, 1200 Main St W, HSC 2N52, Hamilton, ON, Canada L8N 3Z5
    Clin Chim Acta 380:213-6. 2007
    ....
  95. ncbi request reprint Elevated C-reactive protein in acute coronary syndrome presentation is an independent predictor of long-term mortality and heart failure
    Peter A Kavsak
    Department of Pathology and Molecular Medicine, McMaster University, 1200 Main St W, HSC 2N52, Hamilton, ON, Canada L8N 3Z5
    Clin Biochem 40:326-9. 2007
    ..To assess the ability of C-reactive protein (CRP) to predict long-term outcomes in a chest pain population...
  96. ncbi request reprint Effect of myocardial ischemia on cardiac troponin I and T
    Raymond J Carlson
    Crouse Hospital, Syracuse, New York, USA
    Am J Cardiol 89:224-6. 2002
  97. ncbi request reprint Usefulness of detectable levels of troponin, below the 99th percentile of the normal range, as a clue to the presence of underlying coronary artery disease
    Olaf Schulz
    Interventionelle Kardiologie Spandau, Berlin, Germany
    Am J Cardiol 100:764-9. 2007
    ..In conclusion, baseline cTnI was of value in detecting CAD and also during follow-up in predicting the need for further revascularization...
  98. ncbi request reprint Effects of antidepressant medication on morbidity and mortality in depressed patients after myocardial infarction
    C Barr Taylor
    Department of Psychiatry and Behavioral Sciences, Stanford Medical Center, Stanford University School of Medicine, Stanford, CA 94305 5722, USA
    Arch Gen Psychiatry 62:792-8. 2005
    ..Depression after myocardial infarction (MI) is associated with higher morbidity and mortality. Although antidepressants are effective in reducing depression, their use in patients with cardiovascular disease remains controversial...
  99. ncbi request reprint Low heart rate variability and the effect of depression on post-myocardial infarction mortality
    Robert M Carney
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
    Arch Intern Med 165:1486-91. 2005
    ..Depression is associated with an increased risk for mortality after acute myocardial infarction (MI). The purpose of this study was to determine whether low heart rate variability (HRV) mediates the effect of depression on mortality...
  100. ncbi request reprint Impact of contemporary guideline compliance on risk stratification models for acute coronary syndromes in The Registry of Acute Coronary Syndromes
    Martha Gulati
    Rush University Medical Center, Chicago, Illinois, USA
    Am J Cardiol 94:873-8. 2004
    ..The use of established risk scores may overestimate event rates in unselected populations...
  101. ncbi request reprint The Pilot Randomized Study of Nesiritide Versus Dobutamine in Heart Failure (PRESERVD-HF)
    Mihai Gheorghiade
    Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Am J Cardiol 96:18G-25G. 2005
    ..Accordingly, therapies for AHFS that are aimed at improving hemodynamics may affect long-term prognosis by either injuring or salvaging myocardium...