YASUHIRO contact IKEDA

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. pmc Indolactam V/GLP-1-mediated differentiation of human iPS cells into glucose-responsive insulin-secreting progeny
    T Thatava
    Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Gene Ther 18:283-93. 2011
  2. pmc Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency
    Seiga Ohmine
    Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Aging (Albany NY) 4:60-73. 2012
  3. pmc Long-term infection and vertical transmission of a gammaretrovirus in a foreign host species
    Toshie Sakuma
    Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America
    PLoS ONE 7:e29682. 2012
  4. pmc Global gene expression profiling of pancreatic islets in mice during streptozotocin-induced β-cell damage and pancreatic Glp-1 gene therapy
    Jason M Tonne
    Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Dis Model Mech 6:1236-45. 2013
  5. pmc The antiviral spectra of TRIM5α orthologues and human TRIM family proteins against lentiviral production
    Seiga Ohmine
    Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America
    PLoS ONE 6:e16121. 2011
  6. pmc Induced pluripotent stem cells from GMP-grade hematopoietic progenitor cells and mononuclear myeloid cells
    Seiga Ohmine
    Department of Molecular Medicine, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Stem Cell Res Ther 2:46. 2011
  7. pmc Successful disease-specific induced pluripotent stem cell generation from patients with kidney transplantation
    Tayaramma Thatava
    Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Stem Cell Res Ther 2:48. 2011
  8. pmc No association of xenotropic murine leukemia virus-related virus with prostate cancer or chronic fatigue syndrome in Japan
    Rika A Furuta
    Department of Research, Japanese Red Cross Osaka Blood Center, 2 4 43 Morinomiya, Joto ku, Osaka 536 8505, Japan
    Retrovirology 8:20. 2011
  9. pmc No evidence of XMRV in prostate cancer cohorts in the Midwestern United States
    Toshie Sakuma
    Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Retrovirology 8:23. 2011
  10. pmc Long-term cardiac pro-B-type natriuretic peptide gene delivery prevents the development of hypertensive heart disease in spontaneously hypertensive rats
    Alessandro Cataliotti
    Molecular Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Circulation 123:1297-305. 2011

Research Grants

Collaborators

  • T J Nelson
  • Kah Whye Peng
  • T Sakuma
  • Fernando L Martin
  • Greg J Towers
  • Andre Terzic
  • Hiroaki Takeuchi
  • Seiga Ohmine
  • Tayaramma Thatava
  • Jason M Tonne
  • Michael C Deeds
  • Yogish C Kudva
  • Adam S Armstrong
  • Katherine A Hartjes
  • Ryuta Sakuma
  • Alessandro Cataliotti
  • T Thatava
  • Rika A Furuta
  • Michael A Barry
  • Miguel Munoz-Gomez
  • Yogish Kudva
  • Karen A Squillace
  • S Yamada
  • Takeki Sugiyama
  • Y Kudva
  • Yulia Krotova Khan
  • Gerald E Harders
  • Kazuta Yasui
  • Eiji Sato
  • Allan B Dietz
  • Stephen J Russell
  • Fumiya Hirayama
  • Takayuki Miyazawa
  • Jarryd M Campbell
  • Yasuhito Nakatomi
  • Naoko Misawa
  • Lorenzo S Malatino
  • Diego Bellavia
  • Josep Genebriera De Lamo
  • John C Burnett
  • David R Miller
  • S Ohmine
  • Ramakrishna Edukulla
  • Elise A Oehler
  • Jamie L Sundsbak
  • Kouzi Yamaguti
  • R Edukulla
  • Hirohiko Kuratsune
  • Peter C Harris
  • J M Tonne

Detail Information

Publications11

  1. pmc Indolactam V/GLP-1-mediated differentiation of human iPS cells into glucose-responsive insulin-secreting progeny
    T Thatava
    Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Gene Ther 18:283-93. 2011
    ..A pancreatogenic cocktail enriched with ILV/GLP-1 offers a proficient means to specify human iPS cells into glucose-responsive hormone-producing progeny, refining the development of a personalized platform for islet-like cell generation...
  2. pmc Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency
    Seiga Ohmine
    Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Aging (Albany NY) 4:60-73. 2012
    ..Thus, in elderly T2D patients, reprogramming of keratinocytes ensures a senescence-privileged status yielding iPS cells proficient for regenerative applications...
  3. pmc Long-term infection and vertical transmission of a gammaretrovirus in a foreign host species
    Toshie Sakuma
    Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America
    PLoS ONE 7:e29682. 2012
    ..Our results therefore demonstrate long-term asymptomatic infection, low incidence of vertical transmission and limited evolution of XMRV upon transspecies infection of a permissive new host, Mus pahari...
  4. pmc Global gene expression profiling of pancreatic islets in mice during streptozotocin-induced β-cell damage and pancreatic Glp-1 gene therapy
    Jason M Tonne
    Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Dis Model Mech 6:1236-45. 2013
    ..Given the pro-β-cell-survival effects of Cxcl12 (Sdf-1) in inducing GLP-1 production in α-cells, pancreatic GLP-1-mediated Cxcl13 induction might also play a crucial role in maintaining the integrity of β-cells in damaged islets. ..
  5. pmc The antiviral spectra of TRIM5α orthologues and human TRIM family proteins against lentiviral production
    Seiga Ohmine
    Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America
    PLoS ONE 6:e16121. 2011
    ..Although all TRIM family proteins have RBCC domains, it remains elusive whether they possess similar late-restriction activities...
  6. pmc Induced pluripotent stem cells from GMP-grade hematopoietic progenitor cells and mononuclear myeloid cells
    Seiga Ohmine
    Department of Molecular Medicine, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Stem Cell Res Ther 2:46. 2011
    ..One of the key issues for clinical-grade iPSC derivation is the accessibility of donor cells used for reprogramming...
  7. pmc Successful disease-specific induced pluripotent stem cell generation from patients with kidney transplantation
    Tayaramma Thatava
    Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Stem Cell Res Ther 2:48. 2011
    ..Induced pluripotent stem (iPS) cell technology, which allows derivation of patient-specific pluripotent stem cells, could provide a possible alternative modality for kidney replacement therapy for patients with ESRD...
  8. pmc No association of xenotropic murine leukemia virus-related virus with prostate cancer or chronic fatigue syndrome in Japan
    Rika A Furuta
    Department of Research, Japanese Red Cross Osaka Blood Center, 2 4 43 Morinomiya, Joto ku, Osaka 536 8505, Japan
    Retrovirology 8:20. 2011
    ..We also examined blood samples of viral antibody-positive patients with PC and all (both antibody-positive and antibody-negative) patients with CFS for XMRV DNA...
  9. pmc No evidence of XMRV in prostate cancer cohorts in the Midwestern United States
    Toshie Sakuma
    Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Retrovirology 8:23. 2011
    ..To address the association between XMRV infection and PCa, we have tested prostate tissues and human sera for the presence of viral DNA, viral antigens and anti-XMRV antibodies...
  10. pmc Long-term cardiac pro-B-type natriuretic peptide gene delivery prevents the development of hypertensive heart disease in spontaneously hypertensive rats
    Alessandro Cataliotti
    Molecular Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Circulation 123:1297-305. 2011
    ..In the current study, we tested the effects of sustained cardiac proBNP gene delivery on BP, cardiac function, and remodeling in spontaneously hypertensive rats (SHR)...
  11. pmc Early events in retrovirus XMRV infection of the wild-derived mouse Mus pahari
    Toshie Sakuma
    Department of Molecular Medicine, Mayo Clinic, Guggenheim 18 11c, 200 First Street, SW, Rochester, MN 55905, USA
    J Virol 85:1205-13. 2011
    ..These data support the use of Mus pahari as a model for XMRV pathogenesis and as a platform for vaccine and drug development against this potential human pathogen...

Research Grants2

  1. Regulated Long-Term Cardiac BNP Expression in Hypertensive Heart Disease
    YASUHIRO contact IKEDA; Fiscal Year: 2010
    ..We will test if regulated long-term cardiac BNP expression ameliorates HHD. Our results will elucidate the role of BNP in hypertension and may lead to a novel chronic BNP therapy strategy for human HHD. ..