Jonathan Holmes

..To identify specific health-related quality-of-life (HRQOL) concerns for children with intermittent exotropia (IXT) and their parents...

..To report masked superior oblique muscle tightness as a possible mechanism causing A-pattern exotropia with intorsion after inferior rectus muscle recession in the context of thyroid eye disease...

..Induced vertical misalignment may be associated with changes in torsion. We have developed a simple method to monitor intraoperative torsion that may reduce the incidence of vertical deviations...

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..To develop and validate a new parental questionnaire addressing symptoms and health-related quality of life (HRQL) in childhood nasolacrimal duct obstruction (NLDO)...

..Although amblyopia can be successfully treated with patching or atropine, there have been few prospective studies of amblyopia recurrence once treatment is discontinued...

..To develop a presentation protocol for the new Frisby-Davis 2 (FD2) distance stereoacuity test...

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..To develop new methods for quantifying diplopia and test their validity, test-retest reliability, and responsiveness to treatment...

..We now report the association of additional factors with recurrence or regression of amblyopia in this same cohort...

..Future studies are needed to investigate the best treatment strategies for residual amblyopia, whether weaning treatment is needed at the end of a course, and how compliance can be enhanced...

..Successful patching regimens can last as little as 1 h or 2 h a day, and successful atropine regimens as little as one drop twice a week. Intense and extended regimens might not be needed in initial therapy...

..We report a small case series of patients successfully treated using a lateral rectus posterior fixation suture...

..To determine the birth prevalence of visually significant infantile cataract, using population-based comprehensive medical record retrieval, in a defined US population...

..We present a patient with craniosynostosis who underwent bilateral superior oblique tucks to specifically address the excyclotorsion of the globes...

..These data may have a profound influence on our approach to treating this condition. This is indeed an exciting time to be taking care of children with amblyopia, as we anticipate the results of these studies...

..We evaluated success rates with conservative nonsurgical management, botulinum toxin (botox) treatment, strabismus surgery, and a combination of botox treatment and surgery...

..To investigate the course of near stereoacuity in a cohort of children with untreated intermittent exotropia...

..To determine the incidence of sixth nerve palsy in a population-based study, with particular emphasis on associated coexisting medical conditions and to use these data to develop a management algorithm...

..To evaluate the reliability of a new visual acuity testing protocol for children using isolated surrounded HOTV optotypes...

..To evaluate whether nonrecovery from acute traumatic sixth nerve palsy could be predicted from demographic factors or palsy characteristics...

..There are few data on the reproducibility of clinical assessment of ductions and alignment. We evaluated photographic methods that may be used for masked outcome determination in a clinical trial and compared them with clinical measures...

..We conducted a multicenter, nonrandomized, data collection study to evaluate recovery rates of patients treated with either conservative measures or BTX...

..To determine the population-based incidence and cause of cranial nerve palsies affecting ocular motility in children in the circumscribed population of Olmsted County, Minnesota...

..We investigated the effect of hypercarbia on the retinal vasculature of the neonatal rat to determine whether hypercarbia alone could induce preretinal neovascularization analogous to ROP...

..To evaluate the effectiveness of treatment of amblyopia in children aged 7 to 17 years...

..To evaluate whether distance stereoacuity improves following surgery for intermittent exotropia using the Frisby Davis Distance (FD2) and Distance Randot stereotests...

..To compare 2 hours of daily patching (combined with 1 hour of concurrent near visual activities) with a control group of spectacle wear alone (if needed) for treatment of moderate to severe amblyopia in children 3 to 7 years old...

..To compare patching with atropine eyedrops in the treatment of moderate amblyopia (visual acuity, 20/40-20/100) in children aged 7 to 12 years...

..To assess the stability of visual acuity improvement during the first year after cessation of amblyopia treatment other than spectacle wear in children aged 7 to 12 years...

..The much-cited association of systemic hypertension alone with sixth nerve palsy may be coincidental...

..To compare patching and atropine sulfate as treatments for moderate amblyopia in children 18 months after completion of a 6-month randomized trial...

..The purpose of this study was to report the prevalence of sensory monofixation in intermittent exotropia using different stereotests and to determine the risk of misclassifying monofixation based on a single administration of each test...

..To report data on the response of previously untreated strabismic amblyopia to spectacle correction...

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..The purpose of this study was to assess the variability of stereoacuity over one day in children with IXT...

..As a first step in the development of a health-related quality of life (HRQOL) instrument, we conducted in-depth interviews to identify the specific concerns of adults with strabismus...

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..To establish the thresholds for "real change" in stereoacuity by defining long-term test-retest variability as 95% limits of agreement for 4 stereoacuity tests...

..Diplopia associated with INO severely impacts the patient's quality of life and, therefore, treatment should be considered...

..We report the development of a patient-derived, health-related quality-of-life (HRQOL) questionnaire for adults with strabismus...

..To compare diplopia scores obtained with a new diplopia questionnaire to the established Goldmann diplopia field...

..We pooled data across studies to further evaluate the validity of the ATI, to further assess the presence or absence of factors (subscales)...

..Such recovery of stereoacuity may take several months to occur. In our adult series, duration of misalignment did not predict failure to recover stereoacuity...

..To compare 2 hours vs 6 hours of daily patching as treatments for moderate amblyopia in children younger than 7 years...

..The new Preschool Randot test is valuable for quantifying stereopsis in both children and adults. True stereopsis may be rare when a patient has a horizontal deviation > 4 PD...

..The Minnesota Low-Vision Reading Test (MNREAD) has been developed to measure reading speed. An abbreviated version of the MNREAD test was developed that presented only three large paragraphs and would be easier for children to complete...

..A secondary aim was to obtain a preliminary estimate of the effect of near versus non-near activities on amblyopic eye visual acuity, when combined with 2 hours of daily patching...

..The more rigorous Randot tests would be appropriate for determining subtle changes...

..The purpose of this study was to prospectively evaluate a new scale for assessing the level of control in children with intermittent exotropia...

..To evaluate the effectiveness of refractive correction alone for the treatment of untreated anisometropic amblyopia in children 3 to <7 years old...

..Future genetic studies are warranted to investigate the differences between CRSD and HSD rats, which might yield further clues into the pathogenesis of ROP...

..This systematic difference is important when a physician changes testing modality as a child matures and should be considered when interpreting the results of recent and ongoing clinical trials in amblyopia...

..The development and initial validation of patient-derived, health-related quality-of-life (HRQOL) questionnaires for intermittent exotropia (IXT)...

..To compare 2 health-related quality-of-life (HRQOL) instruments: the condition-specific Intermittent Exotropia Questionnaire (IXTQ) and the generic Pediatric Quality of Life Inventory (PedsQL) in children with intermittent exotropia...

..To determine whether visual acuity improvement with Bangerter filters is similar to improvement with patching as initial therapy for children with moderate amblyopia...

..To examine the effect of preoperative alignment stability on postoperative motor outcomes in children who underwent surgery for esotropia...

..To report the test-retest variability of two health-related quality-of-life instruments: the new Adult Strabismus 20 (AS-20) and the National Eye Institute 25-item Visual Function Questionnaire (NEI VFQ-25), in adults with strabismus...

..To compare daily atropine to weekend atropine as prescribed treatments for moderate amblyopia in children younger than 7 years...

..The purpose of this study was to compare these 2 techniques and describe advantages and disadvantages...

..We developed a near ocular dominance test modeled after the distance hole-in-the-card test and assessed both test-retest reliability of four tests of ocular dominance and agreement between tests...

..To determine the amount and time course of binocular visual acuity improvement during treatment of bilateral refractive amblyopia in children three to less than 10 years of age...

..More than 1 surgical procedure and prism are often necessary in the management of chronic sixth nerve palsy...

..The authors investigated the stability of ocular alignment over 18 weeks in children with infantile esotropia (IET), acquired nonaccommodative esotropia (ANAET), or acquired partially accommodative esotropia (APAET)...

..To determine the effect of induced monocular blur on stereoacuity measured with real depth and random dot tests...

..To compare the outcomes of balloon catheter dilation and nasolacrimal intubation as treatment for congenital nasolacrimal duct obstruction after failed probing in children younger than 4 years...

..Few authors have reported data regarding induced acuity deficits. We investigated the effect of Bangerter filters on distance and near optotype acuity, vernier acuity, and contrast sensitivity...

..The high failure rate with conservative management, reported in the literature, supports early surgical intervention...

..To describe how children with intermittent exotropia (IXT) are aware of their exodeviation...

..We sought to develop a new "Distance Randot" test, establish a normative data set for children and adults, and compare with established measures of stereoacuity...

..The study enrolled too few children ages 36 to <48 months to allow a conclusion regarding the probability of treatment success in this age group...

..The outcome is similar regardless of initial treatment with atropine or patching...

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..We sought to describe the change in ocular alignment at 2 years after treatment of amblyopia in children younger than 7 years of age at enrollment...

..This pilot study has shown that remote reading of digital photographs has promise for telemedicine strategies in ROP screening...

..This computerized testing method should be considered when visual acuity is used as an outcome measure in eye research involving children 7 to <13 years old...

..Studies are warranted to investigate the genetic differences between Brown Norway and Sprague Dawley rats in models of ROP. These genetic studies may yield further clues into the pathogenesis of clinical ROP...

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..Ultimately this research will result in better quality of life for patients with strabismus. ..