Affiliation: Mayo Clinic
- Heit J, Spencer F, White R. The epidemiology of venous thromboembolism. J Thromb Thrombolysis. 2016;41:3-14 pubmed publisher..Although independent VTE risk factors and predictors of VTE recurrence have been identified, and effective primary and secondary prophylaxis is available, the occurrence of VTE seems to be relatively constant, or even increasing. ..
- Cohoon K, Ransom J, Leibson C, Ashrani A, Petterson T, Long K, et al. Direct Medical Costs Attributable to Cancer-Associated Venous Thromboembolism: A Population-Based Longitudinal Study. Am J Med. 2016;129:1000.e15-25 pubmed publisher..Venous thromboembolism-attributable costs among patients with active cancer contribute a substantial economic burden and are highest from index to 3 months, but may persist for up to 5 years. ..
- Cohoon K, Leibson C, Ransom J, Ashrani A, Park M, Petterson T, et al. Direct medical costs attributable to venous thromboembolism among persons hospitalized for major operation: a population-based longitudinal study. Surgery. 2015;157:423-31 pubmed publisher..VTE during or after recent hospitalization for major operation contributes a substantial economic burden; VTE-attributable costs are greatest in the initial 3Â months but persist for up to 5Â years. ..
- Heit J, ASHRANI A, Crusan D, McBane R, Petterson T, Bailey K. Reasons for the persistent incidence of venous thromboembolism. Thromb Haemost. 2017;117:390-400 pubmed publisher..Increasing surgery PAR suggests that concurrent efforts to prevent VTE may have been insufficient. ..
- Heit J, Armasu S, Asmann Y, Cunningham J, Matsumoto M, Petterson T, et al. A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q. J Thromb Haemost. 2012;10:1521-31 pubmed publisher..0 and 1.51 for minor allele frequencies=0.05 and 0.5, respectively (?=1×10(-8); 1% VTE prevalence). Apart from F5 rs6025, ABO rs8176719, rs2519093 and F2 rs1799963, additional common and high VTE-risk SNPs among whites are unlikely. ..
- de Andrade M, Armasu S, McCauley B, Petterson T, Heit J. Identification of Genetic Interaction with Risk Factors Using a Time-To-Event Model. Int J Environ Res Public Health. 2017;14: pubmed publisher..We showed that the time-to-event model is a useful approach for identifying potential hazard-modification of the genetic variants when the event of interest (VTE) occurs due to a risk factor (pre- or post-partum). ..