Research Topics
| J T HaysSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Changes in health-related quality of life with smoking cessation treatmentJ Taylor Hays
Mayo Clinic, Mayo Nicotine Dependence Center, Rochester, MN 55905, USA
Eur J Public Health 22:224-9. 2012..We assessed the effects of treatment for tobacco dependence on the health-related QoL in a 52-week randomized controlled trial of varenicline and bupropion sustained release (SR)...
Methylphenidate for treating tobacco dependence in non-attention deficit hyperactivity disorder smokers: a pilot randomized placebo-controlled trialRichard D Hurt
Nicotine Dependence Center, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA
J Negat Results Biomed 10:1. 2011....
Pharmacologic agents for tobacco dependence treatment: 2011 updateJ Taylor Hays
Nicotine Dependence Center, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Curr Atheroscler Rep 14:85-92. 2012..In this review, we provide a current update of pharmacologic agents for tobacco dependence treatment and a discussion of recent controversy regarding adverse effects of some these medications...
A randomized, controlled trial of bupropion sustained-release for preventing tobacco relapse in recovering alcoholicsJ Taylor Hays
Department of Internal Medicine, Mayo Clinic College of Medicine, Mayo Clinic Nicotine Dependence Center, 200 1st Street Southwest, Rochester, MN 55905, USA
Nicotine Tob Res 11:859-67. 2009..We set out to investigate this issue further by conducting a randomized, double-blind, placebo-controlled trial of bupropion sustained-release (SR) for smoking relapse prevention among abstinent alcoholic smokers...
Treating tobacco dependence in light of the 2008 US Department of Health and Human Services clinical practice guidelineJ Taylor Hays
Division of General Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
Mayo Clin Proc 84:730-5; quiz 735-6. 2009..This article briefly reviews the major updates and recommendations from the new guideline and highlights its practical clinical applications...
Residential treatment compared with outpatient treatment for tobacco use and dependenceJ Taylor Hays
Nicotine Dependence Center, Mayo Clinic, Rochester, MN 55905, USA
Mayo Clin Proc 86:203-9. 2011..To compare the effectiveness of outpatient vs residential treatment for tobacco dependence in a large referral practice...
Adherence to treatment for tobacco dependence: association with smoking abstinence and predictors of adherenceJ Taylor Hays
Mayo Clinic Nicotine Dependence Center, 200 1st Street Southwest, Rochester, MN 55905, USA
Nicotine Tob Res 12:574-81. 2010..In this analysis, we assessed adherence to tobacco dependence treatment, association of adherence with abstinence, and predictors of adherence...
Varenicline for tobacco dependence treatment in recovering alcohol-dependent smokers: an open-label pilot studyJ Taylor Hays
Mayo Clinic, Nicotine Dependence Center, Rochester, Minnesota 55905, USA
J Subst Abuse Treat 40:102-7. 2011..No serious adverse events were reported. Varenicline may be a useful aid for treating tobacco dependence among smokers who are in stable recovery from alcohol dependence. Further study of this treatment is warranted...
Adverse effects and tolerability of medications for the treatment of tobacco use and dependenceJ Taylor Hays
Mayo Clinic Nicotine Dependence Center, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Drugs 70:2357-72. 2010..Given these factors, the benefit : risk ratio is strongly in favour of pharmacotherapy for tobacco dependence treatment in virtually all smokers who are motivated to quit...
Efficacy and safety of varenicline for smoking cessationJ Taylor Hays
Nicotine Dependence Center, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Med 121:S32-42. 2008..As the newest agent approved for smoking cessation, the mechanism of action, efficacy, and safety of varenicline...
Trends in smoking-related diseases. Why smoking cessation is still the best medicineJ T Hays
Nicotine Dependence Center, Mayo Clinic, Rochester, MN 55905, USA
Postgrad Med 104:56-62, 65-6, 71. 1998..But what headway has been made in the reduction of related morbidity and mortality? The authors of this article review the current epidemiologic data on smoking-related diseases and make an indisputable case for smoking cessation...
Over-the-counter nicotine patch therapy for smoking cessation: results from randomized, double-blind, placebo-controlled, and open label trialsJ T Hays
Mayo Clinic, Rochester, MN 55905, USA
Am J Public Health 89:1701-7. 1999..The purpose of this study was to determine the efficacy and safety of the nicotine patch for smoking cessation in an over-the-counter environment. The years of study were 1994 to 1995...
Residential (inpatient) treatment compared with outpatient treatment for nicotine dependenceJ T Hays
Nicotine Dependence Center, Division of General Internal Medicine, Mayo Clinic, Rochester, Minn, USA
Mayo Clin Proc 76:124-33. 2001....
Bupropion for the treatment of tobacco dependence: guidelines for balancing risks and benefitsJ Taylor Hays
Mayo Nicotine Dependence Center, Rochester, Minnesota 55905, USA
CNS Drugs 17:71-83. 2003..Recent postmarketing surveillance reports have raised safety concerns about bupropion, although no causal relationship between bupropion and the reported serious adverse events or death has been established...
Bupropion sustained release for treatment of tobacco dependenceJ Taylor Hays
Division of General Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
Mayo Clin Proc 78:1020-4; quiz 1024. 2003....
Development of depression during placebo-controlled trials of bupropion for smoking cessation: case reportsC A Patten
Nicotine Research Center, Mayo Clinic, Rochester, Minn 55905, USA
J Clin Psychiatry 60:436-41. 1999..Recent attention has focused on the relationship between depression and smoking cessation. This article describes 5 cases of severe depression that occurred during 2 multicenter trials using bupropion for smoking cessation...
A community-wide smoking cessation program: Quit and Win 1998 in Olmsted countyI T Croghan
Nicotine Research Center, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
Prev Med 33:229-38. 2001..Quit and Win is a community-wide stop smoking contest to help cigarette smokers stop smoking and educate the general public concerning smoking hazards...
Sustained-release bupropion for pharmacologic relapse prevention after smoking cessation. a randomized, controlled trialJ T Hays
Nicotine Dependence Center, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Ann Intern Med 135:423-33. 2001..6 kg; P = 0.002) and 104 (4.1 kg vs. 5.4 kg; P = 0.016). CONCLUSIONS: In persons who stopped smoking with 7 weeks of bupropion treatment, sustained-release bupropion for 12 months delayed smoking relapse and resulted in less weight gain...
Sibutramine for weight gain attenuation during smoking cessation with varenicline: a pilot studyAmit Sood
General Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Nicotine Tob Res 11:1479-84. 2009..Varenicline is the most effective medication for smoking cessation but does not prevent weight gain. Combining sibutramine and varenicline may facilitate smoking abstinence if weight gain is attenuated...
Combination pharmacotherapy for stopping smoking: what advantages does it offer?Jon O Ebbert
Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Drugs 70:643-50. 2010..Available data suggests that combination therapy may increase abstinence rates compared with monotherapy. However, the cost effectiveness of this approach has not been clearly demonstrated...
Bupropion for pharmacologic relapse prevention to smoking: predictors of outcomeRichard D Hurt
Nicotine Research Center, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
Addict Behav 27:493-507. 2002..These data should encourage others to perform similar pharmacologic relapse prevention studies with this or other pharmacotherapies...
Combination treatment with varenicline and nicotine replacement therapyJon O Ebbert
Mayo Clinic College of Medicine, 200 1st Street Southwest, Rochester, MN 55905, USA
Nicotine Tob Res 11:572-6. 2009..A paucity of data exists regarding the safety and effectiveness of combination treatment with varenicline and nicotine replacement therapy (NRT)...
Treating nondepressed smokers with alcohol dependence in sustained full remission: nicotine patch therapy tailored to baseline serum cotinineRichard D Hurt
Nicotine Dependence Center, Mayo Clinic College of Medicine, 200 First Street South West, Rochester, Minnesota 55905, USA
J Stud Alcohol 66:506-16. 2005....
Varenicline and bupropion sustained-release combination therapy for smoking cessationJon O Ebbert
Mayo Clinic College of Medicine, 200 1st Street Southwest, Rochester, MN 55905, USA
Nicotine Tob Res 11:234-9. 2009..Combination pharmacotherapy with these agents may increase long-term smoking abstinence rates above what is observed with single-agent therapy...
Gender differences among smokers receiving interventions for tobacco dependence in a medical settingIvana T Croghan
Mayo Clinic, Nicotine Dependence Center, 200 First St, SW, Rochester, Minnesota 55905, United States
Addict Behav 34:61-7. 2009..The purpose of this study was to assess differences between women and men receiving treatment for tobacco dependence through a clinical treatment program...
The missing link in tobacco controlJon O Ebbert
Nicotine Dependence Center, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
CMAJ 179:123-4. 2008
Change in perceived stress, partner support, decisional balance, and self-efficacy following residential nicotine dependence treatmentSteven C Ames
Mayo Clinic, Division of Hematology and Oncology, 4500 San Pablo Road, Jacksonville, FL 32224, USA
J Addict Dis 27:73-82. 2008..This study provides new information about how residential treatment impacts psychosocial factors considered to be important predictors of tobacco abstinence in outpatient settings...
Weight concerns among male smokersMatthew M Clark
Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA
Addict Behav 29:1637-41. 2004..Motivation to quit smoking was found to be significantly lower in those with weight concerns (P < .001). Further investigation is needed to enable the tailoring of interventions for weight-concerned male smokers...
Nicotine dependence treatment: perceived health status improvement with 1-year continuous smoking abstinenceIvana T Croghan
Nicotine Research Program, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
Eur J Public Health 15:251-5. 2005....
Body image treatment for weight concerned smokers: a pilot studyMatthew M Clark
Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA
Addict Behav 30:1236-40. 2005..At week 12, 7(35%) of the body image participants had 7-day point prevalence smoking abstinence, compared to 5(24%) of the participants in the weight management group (p=0.505)...
Personality correlates related to tobacco abstinence following treatmentW Michael Hooten
Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
Int J Psychiatry Med 35:59-74. 2005..The five-factor model of personality was used to describe the correlates of smoking abstinence...
Tobacco dependence: why should an oncologist care?Yolanda I Garces
Division of Radiation Oncology, Department of Oncology, Mayo Clinic, 200 First St, SW, Rochester, MN, 55905, USA
J Clin Oncol 21:1884-6. 2003
Treating tobacco dependence in a medical settingRichard D Hurt
Nicotine Dependence Center, Mayo Clinic, Rochester, MN 55905, USA
CA Cancer J Clin 59:314-26. 2009..The effective treatment of tobacco dependence frequently requires tailoring, and often intensifying, interventions (both counseling and pharmacotherapy) to meet the needs of the individual patient...
Gabapentin for smoking cessation: a preliminary investigation of efficacyAmit Sood
Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Nicotine Tob Res 9:291-8. 2007..Our results suggest that gabapentin may increase smoking abstinence. An adequately powered randomized clinical trial assessing different doses of this drug against a placebo would be the reasonable next step...
Treating tobacco dependence: review of the best and latest treatment optionsJon O Ebbert
Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
J Thorac Oncol 2:249-56. 2007..We review the currently available pharmacologic approaches to the treatment of tobacco dependence...
Gabapentin for smoking cessationAmit Sood
Mayo Clinic College of Medicine, 200 1st Street Southwest, Rochester, MN 55905, USA
Nicotine Tob Res 12:300-4. 2010..We conducted a preliminary proof-of-concept study evaluating gabapentin for the treatment of tobacco dependence...
Treatment of tobacco dependenceMichael V Burke
Nicotine Dependence Center, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Mayo Clin Proc 83:479-83; quiz 483-4. 2008..Because tobacco dependence is characterized by relapses and remissions, clinicians should be ready to engage smokers and reengage relapsed smokers with options for new medication strategies and additional counseling resources...
The role of smoking in breast cancer development: an analysis of a Mayo Clinic cohortIvana T Croghan
Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Breast J 15:489-95. 2009..81, p < 0.001). In this referral practice having a personal history of smoking is predictive of breast cancer diagnosis. Further studies are needed to further explore this relationship...
Effects of gender on relapse prevention in smokers treated with bupropion SRDavid Gonzales
Department of Medicine, Oregon Health and Science University, Portland 97201, USA
Am J Prev Med 22:234-9. 2002..Lower abstinence and higher relapse rates are often reported for women treated with NRT. Gender effects for those treated with non-nicotinic, bupropion-hydrochloride sustained release for relapse prevention have not been studied...
The efficacy and safety of varenicline for smoking cessation using a flexible dosing strategy in adult smokers: a randomized controlled trialRaymond Niaura
Brown University, Providence, RI, USA
Curr Med Res Opin 24:1931-41. 2008..To determine whether self-regulated flexible dosing with varenicline tartrate is safe and effective for smoking cessation...
Office-based intervention for tobacco dependenceSusan H Swartz
Center for Tobacco Independence, Maine Medical Center, 22 Bramhall Street, Portland, ME 04102, USA
Med Clin North Am 88:1623-41, xii-xiii. 2004..Specific ways to think systematically about smoking cessation and intervene with patients are discussed. Strategies to implement office-based changes to improve tobacco intervention are then presented...
Characteristics of Air Force personnel who choose pharmacological aids for smoking cessation following an involuntary tobacco ban and tobacco control programRobert C Klesges
Saint Jude Children s Research Hospital, Memphis, TN 38105, USA
Health Psychol 26:588-97. 2007..The objective of this study was to compare characteristics of smokers who did and did not report use of cessation aids as part of a tobacco control program in a military setting (n = 8994)...
Effects of biochemically confirmed smoking cessation on white blood cell countGregory A Abel
Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Mayo Clin Proc 80:1022-8. 2005..2 +/- 1.5 x 10(9)/L; P < .001). CONCLUSION: Biochemically confirmed tobacco abstinence leads to a rapid and sustained decrease in WBC and ANC, possibly reflecting a decrease In an underlying state of tobacco-induced inflammation...
Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trialDouglas E Jorenby
University of Wisconsin School of Medicine and Public Health, Center for Tobacco Research and Intervention, Madison, Wis 53711, USA
JAMA 296:56-63. 2006..Varenicline, a partial agonist at the alpha4beta2 nicotinic acetylcholine receptor, has the potential to aid smoking cessation by relieving nicotine withdrawal symptoms and reducing the rewarding properties of nicotine...
Urinary tobacco alkaloid measurement in patients having thromboangiitis obliteransRichard D Hurt
Mayo Clin Proc 83:1187-8; author reply 1188. 2008
