Research Topics
Species | Jeffrey L GunterSummaryAffiliation: Mayo Clinic Country: USA Publications
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Detail Information
Publications
Methodological considerations for measuring rates of brain atrophyJeffrey L Gunter
Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
J Magn Reson Imaging 18:16-24. 2003..To systematically compare two techniques for measuring brain atrophy rates from serial magnetic resonance imaging (MRI) studies...
Measurement of MRI scanner performance with the ADNI phantomJeffrey L Gunter
Mayo Clinic and Foundation, Rochester, Minnesota 55902, USA
Med Phys 36:2193-205. 2009..If undetected, these errors would have contributed to imprecision in quantitative metrics at over 25% of all enrolling ADNI sites...
Shapes of the trajectories of 5 major biomarkers of Alzheimer diseaseClifford R Jack
Department of Radiology, Mayo Clinic and Foundation, Rochester, Minnesota, USA
Arch Neurol 69:856-67. 2012..To characterize the shape of the trajectories of Alzheimer disease biomarkers as a function of Mini-Mental State Examination (MMSE) score...
An operational approach to National Institute on Aging-Alzheimer's Association criteria for preclinical Alzheimer diseaseClifford R Jack
Department of Radiology, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
Ann Neurol 71:765-75. 2012..A workgroup commissioned by the Alzheimer's Association (AA) and the National Institute on Aging (NIA) recently published research criteria for preclinical Alzheimer disease (AD). We performed a preliminary assessment of these guidelines...
Effect of lifestyle activities on Alzheimer disease biomarkers and cognitionPrashanthi Vemuri
Department of Radiology, Mayo Clinic and Foundation, 200 First St SW, Rochester, MN 55905, USA
Ann Neurol 72:730-8. 2012....
Antemortem differential diagnosis of dementia pathology using structural MRI: Differential-STANDPrashanthi Vemuri
Department of Radiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
Neuroimage 55:522-31. 2011....
Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's diseaseClifford R Jack
Department of Radiology, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
Brain 133:3336-48. 2010....
Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadicsJennifer L Whitwell
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
Brain 135:794-806. 2012..Our analysis suggested that imaging has the potential to be useful to help differentiate C9ORF72 from these other groups at the single-subject level...
Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's diseaseClifford R Jack
Clifford R Jack, Mayo Clinic, Diagnostic Radiology, 200 First Street SW, Rochester, MN 55905, USA
Brain 132:1355-65. 2009..This model implies a complimentary role for MRI and PIB imaging in Alzheimer's disease, with each reflecting one of the major pathologies, amyloid dysmetabolism and neurodegeneration...
Distinct anatomical subtypes of the behavioural variant of frontotemporal dementia: a cluster analysis studyJennifer L Whitwell
Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Brain 132:2932-46. 2009..Our findings suggest behavioural variant of frontotemporal dementia can therefore be subdivided into four different anatomical subtypes...
Alzheimer's disease diagnosis in individual subjects using structural MR images: validation studiesPrashanthi Vemuri
Department of Radiology, Mayo Clinic 200 1st St SW, Rochester, MN 55905, USA
Neuroimage 39:1186-97. 2008..To develop and validate a tool for Alzheimer's disease (AD) diagnosis in individual subjects using support vector machine (SVM)-based classification of structural MR (sMR) images...
Update on the magnetic resonance imaging core of the Alzheimer's disease neuroimaging initiativeClifford R Jack
Department of Radiology, Mayo Clinic, Rochester, MN, USA
Alzheimers Dement 6:212-20. 2010..These experimental sub-studies are designed to demonstrate the feasibility of acquiring useful data in a multicenter (but single vendor) setting for these three emerging MRI applications...
Imaging measures predict progression in progressive supranuclear palsyJennifer L Whitwell
Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Mov Disord 27:1801-4. 2012..The aim of this work was to determine whether the progressive supranuclear palsy rating scale, a measure of disease severity, is associated with neuroanatomical changes in progressive supranuclear palsy...
Rates of brain atrophy and clinical decline over 6 and 12-month intervals in PSP: determining sample size for treatment trialsJennifer L Whitwell
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
Parkinsonism Relat Disord 18:252-6. 2012..Sample size estimates suggest that treatment trials could be performed over this interval, with rate of midbrain atrophy providing the best outcome measure...
Comparison of different methodological implementations of voxel-based morphometry in neurodegenerative diseaseMatthew L Senjem
Department of Radiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
Neuroimage 26:600-8. 2005....
The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methodsClifford R Jack
Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
J Magn Reson Imaging 27:685-91. 2008..The approach taken in ADNI to standardization across sites and platforms of the MRI protocol, postacquisition corrections, and phantom-based monitoring of all scanners could be used as a model for other multisite trials...
Rates of cerebral atrophy in autopsy-confirmed progressive supranuclear palsyKeith A Josephs
Department of Neurology, Mayo Clinic, 200 First Street NW, Rochester, MN 55905, USA
Ann Neurol 59:200-3. 2006..To determine the rates of cerebral atrophy and ventricular expansion in six patients with autopsy confirmed progressive supranuclear palsy (PSP) and multiple antemortem volumetric head MRI scans...
