Leonard L Gunderson

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. pmc Anal carcinoma: impact of TN category of disease on survival, disease relapse, and colostomy failure in US Gastrointestinal Intergroup RTOG 98-11 phase 3 trial
    Leonard L Gunderson
    Mayo Clinic Cancer Center, Scottsdale, Arizona Electronic address
    Int J Radiat Oncol Biol Phys 87:638-45. 2013
  2. pmc The clinical case for proton beam therapy
    Robert L Foote
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Radiat Oncol 7:174. 2012
  3. pmc Revised tumor and node categorization for rectal cancer based on surveillance, epidemiology, and end results and rectal pooled analysis outcomes
    Leonard L Gunderson
    Mayo Clinic Cancer Center Arizona, 13400 East Shea Blvd, Scottsdale, AZ 85259, USA
    J Clin Oncol 28:256-63. 2010
  4. ncbi request reprint Impact of T and N stage and treatment on survival and relapse in adjuvant rectal cancer: a pooled analysis
    Leonard L Gunderson
    Radiation Oncology Department, Mayo Clinic Cancer Center, Scottsdale, AZ 85259, USA
    J Clin Oncol 22:1785-96. 2004
  5. pmc Revised TN categorization for colon cancer based on national survival outcomes data
    Leonard L Gunderson
    Mayo Clinic Cancer Center Scottsdale, Radiation Oncology, 13400 East Shea Blvd, Scottsdale, AZ 85259, USA
    J Clin Oncol 28:264-71. 2010
  6. pmc Long-term update of US GI intergroup RTOG 98-11 phase III trial for anal carcinoma: survival, relapse, and colostomy failure with concurrent chemoradiation involving fluorouracil/mitomycin versus fluorouracil/cisplatin
    Leonard L Gunderson
    Mayo Clinic Arizona, Scottsdale, AZ 85259, USA
    J Clin Oncol 30:4344-51. 2012
  7. ncbi request reprint Impact of T and N substage on survival and disease relapse in adjuvant rectal cancer: a pooled analysis
    Leonard L Gunderson
    Department of Radiation Oncology, Mayo Clinic Scottsdale, Scottsdale, AZ 85259, USA
    Int J Radiat Oncol Biol Phys 54:386-96. 2002
  8. ncbi request reprint Rectal cancer: Preoperative versus postoperative irradiation as a component of adjuvant treatment
    Leonard L Gunderson
    Mayo Medical School, Mayo Clinic Scottsdale, Scottsdale, AZ, USA
    Semin Radiat Oncol 13:419-32. 2003
  9. doi request reprint Integration of radiation oncology with surgery as combined-modality treatment
    Leonard L Gunderson
    Department of Radiation Oncology, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA
    Surg Oncol Clin N Am 22:405-32. 2013
  10. doi request reprint Reduced acute bowel toxicity in patients treated with intensity-modulated radiotherapy for rectal cancer
    Jason M Samuelian
    Department of Radiation Oncology, Mayo Clinic, Scottsdale, AZ, USA
    Int J Radiat Oncol Biol Phys 82:1981-7. 2012

Detail Information

Publications37

  1. pmc Anal carcinoma: impact of TN category of disease on survival, disease relapse, and colostomy failure in US Gastrointestinal Intergroup RTOG 98-11 phase 3 trial
    Leonard L Gunderson
    Mayo Clinic Cancer Center, Scottsdale, Arizona Electronic address
    Int J Radiat Oncol Biol Phys 87:638-45. 2013
    ....
  2. pmc The clinical case for proton beam therapy
    Robert L Foote
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Radiat Oncol 7:174. 2012
    ..We review the clinical case for proton beam therapy. SUMMARY SENTENCE: Proton beam therapy is a technically advanced and promising form of radiation therapy...
  3. pmc Revised tumor and node categorization for rectal cancer based on surveillance, epidemiology, and end results and rectal pooled analysis outcomes
    Leonard L Gunderson
    Mayo Clinic Cancer Center Arizona, 13400 East Shea Blvd, Scottsdale, AZ 85259, USA
    J Clin Oncol 28:256-63. 2010
    ..The AJCC Hindgut Taskforce sought population-based validation that depth of invasion interacts with nodal status to affect survival...
  4. ncbi request reprint Impact of T and N stage and treatment on survival and relapse in adjuvant rectal cancer: a pooled analysis
    Leonard L Gunderson
    Radiation Oncology Department, Mayo Clinic Cancer Center, Scottsdale, AZ 85259, USA
    J Clin Oncol 22:1785-96. 2004
    ..To determine survival and relapse rates by T and N stage and treatment method in five randomized phase III North American rectal adjuvant studies...
  5. pmc Revised TN categorization for colon cancer based on national survival outcomes data
    Leonard L Gunderson
    Mayo Clinic Cancer Center Scottsdale, Radiation Oncology, 13400 East Shea Blvd, Scottsdale, AZ 85259, USA
    J Clin Oncol 28:264-71. 2010
    ..The AJCC Hindgut Taskforce sought population-based validation that depth of invasion and nodal status interact to affect survival...
  6. pmc Long-term update of US GI intergroup RTOG 98-11 phase III trial for anal carcinoma: survival, relapse, and colostomy failure with concurrent chemoradiation involving fluorouracil/mitomycin versus fluorouracil/cisplatin
    Leonard L Gunderson
    Mayo Clinic Arizona, Scottsdale, AZ 85259, USA
    J Clin Oncol 30:4344-51. 2012
    ..The intent of the updated analysis was to determine the long-term impact of treatment on survival (DFS, OS, colostomy-free survival [CFS]), CF, and relapse (locoregional failure [LRF], distant metastasis) in this patient group...
  7. ncbi request reprint Impact of T and N substage on survival and disease relapse in adjuvant rectal cancer: a pooled analysis
    Leonard L Gunderson
    Department of Radiation Oncology, Mayo Clinic Scottsdale, Scottsdale, AZ 85259, USA
    Int J Radiat Oncol Biol Phys 54:386-96. 2002
    ..To determine the rates of survival and disease control by TNM and MAC stage in three randomized North American rectal adjuvant studies...
  8. ncbi request reprint Rectal cancer: Preoperative versus postoperative irradiation as a component of adjuvant treatment
    Leonard L Gunderson
    Mayo Medical School, Mayo Clinic Scottsdale, Scottsdale, AZ, USA
    Semin Radiat Oncol 13:419-32. 2003
    ....
  9. doi request reprint Integration of radiation oncology with surgery as combined-modality treatment
    Leonard L Gunderson
    Department of Radiation Oncology, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA
    Surg Oncol Clin N Am 22:405-32. 2013
    ..The ultimate in contemporary integration of radiation and surgery is found in patients who are candidates for surgery plus both EBRT and IORT...
  10. doi request reprint Reduced acute bowel toxicity in patients treated with intensity-modulated radiotherapy for rectal cancer
    Jason M Samuelian
    Department of Radiation Oncology, Mayo Clinic, Scottsdale, AZ, USA
    Int J Radiat Oncol Biol Phys 82:1981-7. 2012
    ..The purpose of this study was to review our experience using IMRT to treat rectal cancer and report patient clinical outcomes...
  11. ncbi request reprint Chemotherapy, irradiation, and surgery for function-preserving therapy of primary extremity soft tissue sarcomas: initial treatment with ifosfamide, mitomycin, doxorubicin, and cisplatin plus granulocyte macrophage-colony-stimulating factor
    John H Edmonson
    Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 94:786-92. 2002
    ..This single-institution Phase II study describes an effort to control metastasis by the use of two cycles of chemotherapy as the initial preoperative treatment...
  12. ncbi request reprint Use of intraoperative electron beam radiotherapy in the management of retroperitoneal soft tissue sarcomas
    Ivy A Petersen
    Division of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 52:469-75. 2002
    ..To evaluate the disease control, survival results, and tolerance of intraoperative electron beam radiotherapy (IOERT) as a component of treatment for retroperitoneal soft tissue sarcomas...
  13. ncbi request reprint Advancements in radiation techniques for gastric cancer
    Matthew D Callister
    Department of Radiation Oncology, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA
    J Natl Compr Canc Netw 8:428-35; quiz 436. 2010
    ..Initial clinical experience with these technologies shows favorable tolerance and outcomes...
  14. ncbi request reprint Intraoperative electron radiotherapy as a component of salvage therapy for patients with colorectal cancer and advanced nodal metastases
    Michael G Haddock
    Division of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 56:966-73. 2003
    ..To define the survival rates and relapse patterns in patients with isolated advanced nodal metastases secondary to colorectal cancer, treated with curative intent using aggressive combined-modality treatment...
  15. ncbi request reprint Phase III study of adjuvant chemotherapy and radiation therapy compared with chemotherapy alone in the surgical adjuvant treatment of colon cancer: results of intergroup protocol 0130
    James A Martenson
    North Central Cancer Treatment Group, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    J Clin Oncol 22:3277-83. 2004
    ..Some patients with colon cancer have a high risk of local recurrence postoperatively. This trial was undertaken to determine whether radiation therapy added to an adjuvant chemotherapy regimen improves outcome in high-risk patients...
  16. doi request reprint Combined modality therapy including intraoperative electron irradiation for locally recurrent colorectal cancer
    Michael G Haddock
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 79:143-50. 2011
    ..To evaluate survival, relapse patterns, and prognostic factors in patients with colorectal cancer relapse treated with curative-intent therapy, including intraoperative electron radiation therapy (IOERT)...
  17. pmc Neoadjuvant chemoradiation compared to neoadjuvant radiation alone and surgery alone for Stage II and III soft tissue sarcoma of the extremities
    Kelly K Curtis
    Department of Radiation Oncology, Mayo Clinic, Scottsdale, AZ 85259, USA
    Radiat Oncol 6:91. 2011
    ..We present outcomes with NCR using a variety of chemotherapy regimens compared to neoadjuvant radiation without chemotherapy (NR) and surgery alone (SA)...
  18. ncbi request reprint Breast cancer-related lymphedema
    Rosalyn M Morrell
    Department of Radiation Oncology, Mayo Clinic College of Medicine, Scottsdale, Arizona 85259, USA
    Mayo Clin Proc 80:1480-4. 2005
    ..This review presents an overview of the pathophysiology, diagnosis, prevention, and treatment of breast cancer-related lymphedema...
  19. doi request reprint Unresectable colorectal cancer can be cured with multimodality therapy
    Kellie L Mathis
    Department of Surgery, Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, MN 55905, USA
    Ann Surg 248:592-8. 2008
    ....
  20. doi request reprint Adjuvant radiotherapy and chemotherapy for pancreatic carcinoma: the Mayo Clinic experience (1975-2005)
    Michele M Corsini
    Department of Radiation Oncology the Division of Gastroenterologic and General Surgery, Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 26:3511-6. 2008
    ..To determine prognostic factors and impact of adjuvant chemotherapy (CT) and radiotherapy (RT) on overall survival (OS) after resection of pancreatic adenocarcinoma...
  21. doi request reprint Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial
    Jaffer A Ajani
    Department of Gastrointestinal Medical Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Mail Stop 426, Houston, Texas 77030, USA
    JAMA 299:1914-21. 2008
    ..Chemoradiation as definitive therapy is the preferred primary therapy for patients with anal canal carcinoma; however, the 5-year disease-free survival rate from concurrent fluorouracil/mitomycin and radiation is only approximately 65%...
  22. doi request reprint Locoregional control remains a critical issue in gastric cancer
    Jolie Ringash
    Gastric Cancer 11:64-5. 2008
  23. ncbi request reprint Long-term results of RTOG trial 8911 (USA Intergroup 113): a random assignment trial comparison of chemotherapy followed by surgery compared with surgery alone for esophageal cancer
    David P Kelsen
    Gastrointestinal Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Clin Oncol 25:3719-25. 2007
    ..The relationship between resection type and between tumor response and outcome were also analyzed...
  24. ncbi request reprint Surgical pathology stage by American Joint Commission on Cancer criteria predicts patient survival after preoperative chemoradiation for localized gastric carcinoma
    Pooja R Rohatgi
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer 107:1475-82. 2006
    ..Therefore, the authors hypothesized that surgical pathology stage would be a better prognosticator of overall survival (OS) than baseline stage...
  25. ncbi request reprint The Mayo Clinic experience with multimodality treatment of locally advanced or recurrent colon cancer
    William E Taylor
    Department of Surgery, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Ann Surg Oncol 9:177-85. 2002
    ..Since 1981, 100 colon cancer patients have been treated with combination therapy including surgical resection, chemotherapy, and external plus intraoperative radiotherapy...
  26. ncbi request reprint Radiation treatment parameters in the adjuvant postoperative therapy of gastric cancer
    Joel E Tepper
    Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
    Semin Radiat Oncol 12:187-95. 2002
    ..These should be used as guides for defining appropriate field arrangements for the adjuvant postoperative therapy of gastric cancer...
  27. ncbi request reprint Acute diarrhea during adjuvant therapy for rectal cancer: a detailed analysis from a randomized intergroup trial
    Robert C Miller
    North Central Cancer Treatment Group, Coordinating Center, Rochester, MN, USA
    Int J Radiat Oncol Biol Phys 54:409-13. 2002
    ..Toxicity from a previously reported randomized clinical trial was analyzed to quantify the difference in this risk. Additionally, the persistence of diarrhea after RT was analyzed...
  28. pmc Curative potential of multimodality therapy for locally recurrent rectal cancer
    Dieter Hahnloser
    Division of Colon and Rectal Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Ann Surg 237:502-8. 2003
    ..To assess the results of multimodality therapy for patients with recurrent rectal cancer and to analyze factors predictive of curative resection and prognostic for overall survival...
  29. ncbi request reprint Chemoradiation for resectable gastric cancer
    Henry Q Xiong
    Department of Gastrointestinal Medical Oncology at The University of Texas MD Anderson Cancer Center, TX 77030, USA
    Lancet Oncol 4:498-505. 2003
    ..Preoperative chemotherapy or chemoradiation has been accepted to have a theoretical advantage over postoperative therapy and has now been shown to be a feasible option. Its efficacy, however, remains to be tested...
  30. ncbi request reprint Future directions in intraoperative radiation therapy
    Hollis W Merrick
    Department of Surgery, Medical College of Ohio, 3065 Arlington Avenue, Toledo, OH 43614, USA
    Surg Oncol Clin N Am 12:1099-105. 2003
    ....
  31. ncbi request reprint Palliative treatment of rectal cancer: is radiotherapy alone a good option?
    Christopher G Willett
    Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
    J Gastrointest Surg 8:277-9. 2004
  32. ncbi request reprint Recursive partitioning analysis of pretreatment variables of 416 patients with locoregional esophageal cancer treated with definitive concomitant chemoradiotherapy on Intergroup and Radiation Therapy Oncology Group trials
    Charles R Thomas
    Department of Radiation Oncology, The University of Texas Health Science Center, San Antonio, TX 78229 3900, USA
    Int J Radiat Oncol Biol Phys 58:1405-10. 2004
    ....
  33. ncbi request reprint Adjuvant external beam radiation therapy with concurrent chemotherapy in the management of gallbladder carcinoma
    John J Kresl
    Division of Radiation Oncology, Mayo Clinic and Mayo Foundation, Rochester, MN, USA
    Int J Radiat Oncol Biol Phys 52:167-75. 2002
    ..This study was performed to evaluate the outcome of patients with gallbladder cancer who received postoperative concurrent chemotherapy and radiation therapy...
  34. ncbi request reprint Endocavitary radiation therapy for rectal adenocarcinoma: 10-year results
    Sophie Lavertu
    Division of Radiation Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Clin Oncol 26:508-12. 2003
    ..In conclusion, radiation therapy resulted in a local control rate of 76% at 10 years in curatively treated patients. Although most patients experience toxicity from this treatment, loss of sphincter function is rare...
  35. ncbi request reprint Gastric cancer--patterns of relapse after surgical resection
    Leonard L Gunderson
    Department of Radiation Oncology, Mayo Medical School and Mayo Foundation, Rochester, MN 55905, USA
    Semin Radiat Oncol 12:150-61. 2002
    ..Implications for adjuvant therapy are summarized...
  36. ncbi request reprint Intraoperative electron-beam radiotherapy and ureteral obstruction
    Robert C Miller
    Division of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 64:792-8. 2006
    ..To quantify the risk of ureteral obstruction (UO) after intraoperative electron-beam radiotherapy (IOERT)...
  37. ncbi request reprint Intraabdominal desmoplastic small round cell tumors: a diagnostic and therapeutic challenge
    Imran Hassan
    Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA
    Cancer 104:1264-70. 2005
    ..To the authors' knowledge, only limited data are available on the natural history and optimal treatment of this disease...