Research Topics
| Richard J GraySummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
High-fidelity, low-cost, automated method to assess laparoscopic skills objectivelyRichard J Gray
Department of Surgery, Mayo Clinic, Scottsdale, Arizona 85259, USA
J Surg Educ 69:335-9. 2012..We sought to define the extent to which a motion analysis-based assessment system constructed with simple equipment could measure technical skill objectively and quantitatively...
An update on adjuvant interferon for melanomaRichard J Gray
Division of General Surgery, Mayo Clinic, Arizona, USA
Cancer Control 9:16-21. 2002..Effective adjuvant therapy is needed for this patient population...
Navigating murky waters: a modern treatment algorithm for nipple dischargeRichard J Gray
Department of General Surgery, Mayo Clinic Arizona, 5777 E Mayo Blvd, Phoenix, AZ 85054, USA
Am J Surg 194:850-4; discussion 854-5. 2007..Many women with nipple discharge undergo operative duct excision with few actually having carcinoma...
Breast-conserving therapy and sentinel lymph node biopsy are feasible in cancer patients with previous implant breast augmentationRichard J Gray
Department of Surgery, Mayo Clinic, 13400 East Shea Blvd, Scottsdale, AZ 85259, USA
Am J Surg 188:122-5. 2004..The role of sentinel lymph node (SLN) biopsy in these patients is unknown...
The optimal management of the axillae of patients with microinvasive breast cancer in the sentinel lymph node eraRichard J Gray
Department of General Surgery, Mayo Clinic Arizona, 5777 E Mayo Blvd, Phoenix, AZ 85054, USA
Am J Surg 194:845-8; discussion 848-9. 2007..For patients with microinvasive breast cancer, the value of intraoperative analysis of sentinel lymph nodes (SLNs) and complete axillary lymph node dissection (CALND) is not well known...
A concordance study of subareolar and subdermal injections for breast cancer sentinel lymph node mappingRichard J Gray
Department of Surgery, Section of Surgical Oncology, Mayo Clinic, Scottsdale, AZ 85259, USA
Am J Surg 188:423-5. 2004..There is disagreement regarding the preferred injection site for breast sentinel lymph node mapping...
Sentinel lymph node metastases detected by immunohistochemistry only do not mandate complete axillary lymph node dissection in breast cancerRichard J Gray
Section of Surgical Oncology, Department of Surgery, Mayo Clinic, Scottsdale, Arizona 85259, USA
Ann Surg Oncol 11:1056-60. 2004..The significance of breast cancer sentinel lymph node (SLN) metastases detected only by immunohistochemistry staining (IHC) remains poorly understood. This study attempted to quantify the risk of non-SLN metastases...
Injection of (99m)Tc-labeled sulfur colloid the day before operation for breast cancer sentinel lymph node mapping is as successful as injection the day of operationRichard J Gray
Department of Surgery, Section of Surgical Oncology, CB Surgery, Mayo Clinic, Scottsdale, AZ 85259, USA
Am J Surg 188:685-9. 2004..We investigated whether the timing of injection of (99m)Tc-labeled sulfur colloid (radiocolloid) significantly influenced the success of breast cancer sentinel lymph node (SLN) mapping...
Can lymphatic drainage of head and neck melanoma be predicted?Jesse D Jensen
Midwestern University, Arizona College of Osteopathic Medicine, Glendale, Arizona, USA
J Surg Oncol 103:751-5. 2011..The lymphatic drainage patterns of the head and neck (H&N) is complex. Therefore, identification of the sentinel lymph node (SLN) for H&N melanoma can be challenging...
Current status of radioactive seed for localization of non palpable breast lesionsJames W Jakub
Department of Surgery, Mayo Clinic, Rochester, MN, USA
Am J Surg 199:522-8. 2010..This review highlights the literature regarding RSL, including safety, the ease of the procedure, billing, and oncologic outcomes...
Preoperative predictors of nipple-areola complex involvement for patients undergoing mastectomy for breast cancerJulie A Y Billar
Department of General Surgery, Mayo Clinic in Arizona, Phoenix, AZ, USA
Ann Surg Oncol 18:3123-8. 2011..Proper patient selection is important for nipple-sparing mastectomy, and we aimed to identify preoperative factors predictive of pathologic nipple-areola complex (NAC) involvement to assist with surgical planning...
Inadequate margins of excision when undergoing mastectomy for breast cancer: which patients are at risk?Fariha Sheikh
Section of Surgical Oncology, Department of General Surgery, Mayo Clinic in Arizona, Phoenix, AZ, USA
Ann Surg Oncol 18:952-6. 2011..We analyzed the margin status and risk factors for inadequate margins among patients who underwent skin-sparing mastectomies (SSM) and traditional total mastectomies (TM)...
DIEP and pedicled TRAM flaps: a comparison of outcomesPatrick B Garvey
Division of General Surgery, Mayo Clinic, Scottsdale, Arizona, USA
Plast Reconstr Surg 117:1711-9; discussion 1720-1. 2006..These data support the DIEP flap as the preferred option over the pedicled TRAM flap for autologous breast reconstruction in postmastectomy patients...
The impact of biopsy technique on upstaging, residual disease, and outcome in cutaneous melanomaGenevieve L Egnatios
Department of Dermatology, Mayo Clinic Arizona, Scottsdale, AZ, USA
Am J Surg 202:771-7; discussion 777-8. 2011..Herein, we examine the influence of biopsy technique on residual disease in melanoma WLE specimens and on upstaging...
Radioactive seed localization for nonpalpable breast lesions: review of 1,000 consecutive procedures at a single institutionLee J McGhan
Department of Surgery, Division of Surgical Oncology, Mayo Clinic, Phoenix, Arizona, USA
Ann Surg Oncol 18:3096-101. 2011..Radioactive seed localization (RSL) is an alternative to wire localization for nonpalpable breast lesions, with reported lower rates of positive surgical margins...
Risk factors associated with local and in-transit recurrence of cutaneous melanomaChee Chee H Stucky
Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ 85054, USA
Am J Surg 200:770-4; discussion 774-5. 2010..Understanding the risk factors for local and in-transit recurrences (LR/ITR) may help facilitate methods of prevention, early detection, and treatment...
Metastasectomy and surgical resection of the primary tumor in patients with stage IV breast cancer: time for a second look?Barbara A Pockaj
Department of Surgery, Mayo Clinic, Scottsdale, AZ, USA
Ann Surg Oncol 17:2419-26. 2010..It is time to conduct a carefully designed randomized trial to see whether surgery in stage IV breast cancer does indeed warrant a second look...
Use of preoperative magnetic resonance imaging for invasive lobular cancer: good, better, but maybe not the best?Lee J McGhan
Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA
Ann Surg Oncol 17:255-62. 2010..Invasive lobular cancer (ILC) of the breast is difficult to diagnose clinically and radiologically. It is hoped that preoperative magnetic resonance imaging (MRI) can improve evaluation of extent of disease...
Influence of uncommon histology on breast conservation therapy for breast cancer-biology dictates technique?Nabil Wasif
Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ 85054, USA
J Surg Oncol 105:586-90. 2012..Although trends and variations in the use of breast conservation therapy (BCT) for ductal carcinoma have been studied, little is known about uncommon breast cancer histologies...
Validation of the updated 7th edition AJCC TNM staging criteria for gastric adenocarcinomaLee J McGhan
Department of Surgery, Section of Surgical Oncology, Mayo Clinic Hospital, 5777 East Mayo Boulevard, Phoenix, AZ 85054, USA
J Gastrointest Surg 16:53-61; discussion 61. 2012..Our goal was to validate the new staging system using a cancer registry...
Triple-negative breast cancers: unique clinical presentations and outcomesJulie A Y Billar
Department of General Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA
Ann Surg Oncol 17:384-90. 2010..Triple-negative (TN) breast cancers lack estrogen receptor (ER), progesterone receptor (PR), and HER2/neu amplification (HER2). Few studies have been dedicated to characterizing this subset of cancer...
Increase in contralateral prophylactic mastectomy: echoes of a bygone era? Surgical trends for unilateral breast cancerChee Chee H Stucky
Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA
Ann Surg Oncol 17:330-7. 2010..The goal of this study was to determine factors associated with CPM...
Positive margins after breast-conserving therapy: localization technique or tumor biology?Fariha Sheikh
Section of Surgical Oncology, Department of Surgery, Mayo Clinic in Arizona, Phoenix, AZ 85054, USA
Am J Surg 202:281-5. 2011..The relative contributions of patient and tumor factors versus radiologic localization technique to the rates of inadequate margins of excision in breast-conserving therapy have not been defined...
Desmoplastic melanoma - the step-child in the melanoma family?Nabil Wasif
Department of Surgery, Section of Surgical Oncology, Mayo Clinic Arizona, Phoenix, AZ 85054, USA
J Surg Oncol 103:158-62. 2011..Desmoplastic melanoma (DM) is a rare variant of cutaneous melanoma. Our goal was to study the surgical management of DM, identify prognostic factors, and impact of treatment options...
Acute and chronic results of adjuvant radiotherapy after mastectomy and Transverse Rectus Abdominis Myocutaneous (TRAM) flap reconstruction for breast cancerMichele Y Halyard
Department of Radiation Oncology, Mayo Clinic, Scottsdale, Arizona 85259, USA
Am J Clin Oncol 27:389-94. 2004..quot; We conclude that TRAM flaps can be irradiated with few complications and acceptable cosmetic results...
Quality of life after breast cancer surgery: What have we learned and where should we go next?Barbara A Pockaj
Division of General Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ 85054, USA
J Surg Oncol 99:447-55. 2009..Although multiple studies have evaluated breast surgery quality-of-life outcomes, the data are inconsistent. This factor is important to consider when counseling patients and defining surgical quality measures...
A multi-site validation trial of radioactive seed localization as an alternative to wire localizationJenevieve H Hughes
Department of Surgery, Mayo Clinic, Scottsdale, Arizona 85259, USA
Breast J 14:153-7. 2008..015). RSL is safe, effective, and compared to WL, reduces the rates of intraoperative re-excision and reoperation for positive margins by 68%. Patient satisfaction is improved with RSL. We strongly favor RSL over WL...
The impact of obesity on breast cancer: a retrospective reviewDanielle J Haakinson
Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA
Ann Surg Oncol 19:3012-8. 2012..Obesity has been linked to many adverse health consequences, including breast cancer; however, the impact on clinical presentation, tumor characteristics, and survival outcomes has yet to be clearly defined...
Disparity between actual case volume and the perceptions of case volume needed to train competent general surgeonsFariha Sheikh
Department of Surgery, Mayo Clinic College of Medicine, Phoenix, Arizona 85054, USA
J Surg Educ 67:371-5. 2010..The objective of this study was to determine if resident expectations of case requirements differed significantly from faculty expectations and/or national and program averages...
Does magnetic resonance imaging accurately predict residual disease in breast cancer?Chee Chee H Stucky
Department of Surgery, Mayo Clinic, 5777 E Mayo Blvd, Phoenix, AZ 85054, USA
Am J Surg 198:547-52. 2009..The accuracy of magnetic resonance imaging (MRI) in identifying residual disease after breast conservation therapy (BCT) is unclear...
Older age independently predicts a lower risk of sentinel lymph node metastasis in breast cancerJason Caywood
Department of Surgery, Section of Surgical Oncology, Mayo Clinic, 13400 E. Shea Boulevard, Scottsdale, AZ 85259, USA
Ann Surg Oncol 12:1061-5. 2005..CONCLUSIONS: In addition to known risk factors, age independently predicts the risk of SLN metastasis in breast cancer. Angiolymphatic invasion seems to be a more powerful predictor of SLN metastasis in older patients...
Diagnosis and treatment of malignant melanoma of the footRichard J Gray
Division of General Surgery, Mayo Clinic, Scottsdale, AZ 85259, USA
Foot Ankle Int 27:696-705. 2006..Reconstructive surgical procedures had a high rate of complications; however, overall functional outcomes were good. Stage of cancer at diagnosis was associated with systemic metastases...
Is excisional biopsy indicated for patients with lobular neoplasia diagnosed on percutaneous core needle biopsy of the breast?Bryan Mulheron
Department of Surgery, Mayo Clinic, 5777 E Mayo Boulevard, Phoenix, AZ 85054, USA
Am J Surg 198:792-7. 2009..The value of excisional biopsy for patients with lobular neoplasia diagnosed by core needle breast biopsy is controversial...
Outpatient surgery performed in an ambulatory surgery center versus a hospital: comparison of perioperative time intervalsTerrence L Trentman
Department of Anesthesiology, Mayo Clinic Arizona, Phoenix, AZ, USA
Am J Surg 200:64-7. 2010..This change allowed a comparison of perioperative time intervals for patients undergoing these procedures at an outpatient facility versus a hospital...
Underuse of curative surgery for early stage upper gastrointestinal cancers in the United StatesLee J McGhan
Department of Surgery, Mayo Clinic Hospital, Phoenix, Arizona 85054, USA
J Surg Res 177:55-62. 2012..Surgery is the cornerstone of potentially curative therapy for upper gastrointestinal cancer. We analyzed the patterns of treatment regarding the use of surgery for early-stage upper gastrointestinal cancer in the United States...
Atypical ductal hyperplasia on core biopsy: an automatic trigger for excisional biopsy?Lee J McGhan
Section of Surgical Oncology, Department of Surgery, Mayo Clinic Hospital, Mayo Clinic, Phoenix, AZ, USA
Ann Surg Oncol 19:3264-9. 2012..The study goal was to identify patients who may potentially forego excisional biopsy if the risk of upstaging is low...
Optimal management and challenges in treatment of upper facial melanomaJohn P Berdahl
Division of General Surgery, Mayo Clinic, Scottsdale, AZ 85259, USA
Ann Plast Surg 57:616-20. 2006..Two patients (5%) died, one of an unknown cause and the other of metastatic melanoma. We concluded that oncologic surgery can result in good local disease control in patients with upper facial melanoma...
A significant number of women present with palpable breast cancer even with a normal mammogram within 1 yearDanielle J Haakinson
Department of Surgery, Mayo Clinic, Phoenix, AZ 85054, USA
Am J Surg 200:712-7; discussion 717-8. 2010..Although mammography is the gold standard for breast cancer screening, clinical breast examination (CBE) and self breast examination (SBE) are important adjuncts whose utility has been questioned...
Development of computer-based training to enhance resident physician management of inpatient diabetesCurtiss B Cook
Division of Endocrinology and the Division of Preventive, Occupational, and Aerospace Medicine, Mayo Clinic, Scottsdale, Arizona 85259, USA
J Diabetes Sci Technol 3:1377-87. 2009..Treating hyperglycemia promotes better outcomes among inpatients. Knowledge deficits about management of inpatient diabetes are prevalent among resident physicians, which may affect the care of a substantial number of these patients...
Malignant peripheral nerve sheath tumors (MPNST): the Mayo Clinic experienceChee Chee H Stucky
Department of General Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA
Ann Surg Oncol 19:878-85. 2012..Malignant peripheral nerve sheath tumors (MPNST) are a rare form of soft tissue sarcoma with few studies reporting on patient outcomes and prognostic variables...
The deep inferior epigastric perforator flap for breast reconstruction in overweight and obese patientsPatrick B Garvey
Division of General Surgery, Mayo Clinic Scottsdale, Scottsdale, Ariz 85259, USA
Plast Reconstr Surg 115:447-57. 2005....
Is breast cancer sentinel lymph node mapping valuable for patients in their seventies and beyond?Lisa E McMahon
Section of Surgical Oncology, Department of Surgery, Mayo Clinic, Scottsdale, AZ 85259, USA
Am J Surg 190:366-70. 2005..Sentinel lymph node (SLN) dissection can accomplish axillary staging with less morbidity, but it is unclear if it alters subsequent therapy...
Radioactive seed localization of nonpalpable breast lesions is better than wire localizationRichard J Gray
Department of Surgery, Section of Surgical Oncology, Mayo Clinic, Scottsdale, AZ 85259, USA. gray.richard @mayo.edu
Am J Surg 188:377-80. 2004..CONCLUSIONS: RSL is effective and safe, and this procedure significantly improved the rate of negative margins in the first specimen and the rate of reoperation for positive margins compared to WL. We highly favor RSL over WL...
Changing surgical therapy for melanoma of the external earBarbara A Pockaj
Department of Surgery, Mayo Clinic, Scottsdale, Arizona 85259, USA
Ann Surg Oncol 10:689-96. 2003..The purpose of this study was to evaluate the prognostic variables and clinical ramifications of melanoma of the ear...
Malignant melanoma in the elderly: different regional disease and poorer prognosisJames B Macdonald
1 Department of Dermatology, Mayo Clinic Arizona, 5777 E Mayo Boulevard, Phoenix, AZ 85054, USA
J Cancer 2:538-43. 2011..Melanoma in the elderly is more common on the head and neck. Higher incidence of local/in-transit metastases is seen among the elderly. Five-year disease-specific mortality and overall mortality are both worse for these patients...
Breast cancer: presentation and intervention in women with gastrointestinal metastasis and carcinomatosisElisabeth C McLemore
Division of General Surgery, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, Arizona 85259, USA
Ann Surg Oncol 12:886-94. 2005..CONCLUSIONS: Gastrointestinal metastasis occurred more often in patients with invasive lobular carcinoma. Surgical intervention did not significantly extend overall survival but may be considered in a select group of patients...
Current surgery for breast cancerBarbara A Pockaj
Section of Surgical Oncology, Department of Surgery, Mayo Clinic Arizona, 5777 E Mayo Blvd, Phoenix, AZ 85054, USA
Future Oncol 5:465-79. 2009..Herein, we present a review of the current surgical therapy of invasive breast cancer...
Scientific Presentation Award: The impact of magnetic resonance imaging on surgical treatment of invasive breast cancerSusanne G Carpenter
Department of General Surgery, Mayo Clinic, 5777 E Mayo Blvd, Phoenix, AZ 85028, USA
Am J Surg 198:475-81. 2009..The purpose of this study was to examine the relationship between magnetic resonance imaging (MRI) and surgical treatment of invasive breast cancer (IBC)...
Radiation safety with use of I-125 seeds for localization of nonpalpable breast lesionsWilliam Pavlicek
Department of Diagnostic Radiology, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA
Acad Radiol 13:909-15. 2006..Additional regulatory aspects included institutional review board approval, physician credentialing, off-label use, and governmental licensing...
Reduced T-cell and dendritic cell function is related to cyclooxygenase-2 overexpression and prostaglandin E2 secretion in patients with breast cancerBarbara A Pockaj
Department of Surgery, Mayo Clinic College of Medicine, Scottsdale, Arizona 85259, USA
Ann Surg Oncol 11:328-39. 2004..CONCLUSIONS: COX-2-induced PGE2 may contribute to immunosuppression and may directly block antitumor immunity while promoting tumor growth, providing us with the rationale for using COX-2 inhibition combined with immunotherapy...
Hemosuccus Pancreaticus in the Era of Capsule Endoscopy and Double Balloon Enteroscopy Complicated by Multifocal Mycobacterium chelonae/abscessus InfectionShabana F Pasha
Division of Gastroenterology and Hepatology, Mayo Clinic Scottsdale, Scottsdale, Ariz, USA
Case Rep Gastroenterol 1:38-47. 2007..This report describes a patient with hemosuccus pancreaticus diagnosed in the era of video capsule endoscopy and double balloon enteroscopy, whose management was complicated by multifocal Mycobacteria chelonae/abscessus infection...
