Research Topics
Species | Yonas E GedaSummaryAffiliation: Mayo Clinic Country: USA Publications
Research Grants
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Detail Information
Publications
Caloric intake, aging, and mild cognitive impairment: a population-based studyYonas E Geda
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
J Alzheimers Dis 34:501-7. 2013..96, 95% CI 1.26-3.06, p = 0.003) as compared to the reference group. Therefore, high caloric intake was associated with MCI but not moderate caloric intake. This association is not necessarily a cause-effect relationship...- Mild cognitive impairment: a subset of minor neurocognitive disorder?Yonas E Geda
College of Medicine, Mayo Clinic, Scottsdale, AZ, USA
Am J Geriatr Psychiatry 20:821-6. 2012..Questionnaire-based observational studies will continue to be useful until such a time that validated biomarkers, be it chemical or neuroimaging, become widely available and reasonably affordable... 
Mild cognitive impairment in older adultsYonas E Geda
Department of Psychiatry and Psychology, Mayo Clinic, Scottsdale, AZ, USA
Curr Psychiatry Rep 14:320-7. 2012..However, there are also ongoing research studies to understand high-risk groups for non-Alzheimer's dementia...- Computer activities, physical exercise, aging, and mild cognitive impairment: a population-based studyYonas E Geda
Department of Psychiatry and Psychology, Mayo Clinic, Scottsdale, AZ 85259, USA
Mayo Clin Proc 87:437-42. 2012..To examine the association between computer use, physical exercise, aging, and mild cognitive impairment (MCI)... 
Neuropsychiatric features in 36 pathologically confirmed cases of corticobasal degenerationYonas E Geda
Department of Psychiatry, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, MN 55905, USA
J Neuropsychiatry Clin Neurosci 19:77-80. 2007..No patient experienced visual hallucinations. If confirmed by a prospective study, the absence of visual hallucinations may help to distinguish corticobasal syndrome from other parkinsonian syndromes...- Depression, apolipoprotein E genotype, and the incidence of mild cognitive impairment: a prospective cohort studyYonas E Geda
Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, Minn, USA
Arch Neurol 63:435-40. 2006..It remains unknown whether depression and apolipoprotein E genotype are risk factors for incident mild cognitive impairment (MCI)... - Engaging in cognitive activities, aging, and mild cognitive impairment: a population-based studyYonas E Geda
Department of Health Sciences Research, Divisions of Epidemiology, College of Medicine, Mayo Clinic, Rochester MN, Wheaton University Topazian, Chicago IL, USA
J Neuropsychiatry Clin Neurosci 23:149-54. 2011..The equally high prevalence of reading newspapers in both groups yielded no significant between-group difference... - De novo genesis of neuropsychiatric symptoms in mild cognitive impairment (MCI)Yonas E Geda
Department of Psychiatry and Psychology, Mayo Clinic Rochester, MN 55905, USA
Int Psychogeriatr 16:51-60. 2004..There is inadequate information regarding the neuropsychiatric aspect of Mild Cognitive Impairment (MCI)... - Prevalence of neuropsychiatric symptoms in mild cognitive impairment and normal cognitive aging: population-based studyYonas E Geda
Department of Psychiatry and Psychology, College of Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Arch Gen Psychiatry 65:1193-8. 2008..Little is known about the population-based prevalence of neuropsychiatric symptoms in mild cognitive impairment (MCI)... - Physical exercise, aging, and mild cognitive impairment: a population-based studyYonas E Geda
Mayo Clinic, 200 First Street SW, Rochester, MN 55905
Arch Neurol 67:80-6. 2010..Physical exercise is associated with decreased risk of dementia and Alzheimer disease... - The Mayo Clinic Study of Aging: design and sampling, participation, baseline measures and sample characteristicsRosebud O Roberts
Division of Epidemiology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Neuroepidemiology 30:58-69. 2008..The objective of this study was to establish a prospective population-based cohort to investigate the prevalence, incidence and risk factors for mild cognitive impairment (MCI) and dementia... - Implicit learning of sequential regularities and spatial contexts in corticobasal syndromeSelam Negash
Mayo Clinic, Rochester, MN 55905, USA
Neurocase 13:133-43. 2007..These findings provide the first characterization of implicit learning systems in CBS, and show that the two systems are differentially affected in patients with CBS... - Vegetables, unsaturated fats, moderate alcohol intake, and mild cognitive impairmentRosebud O Roberts
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA roberts rosebud mayo edu
Dement Geriatr Cogn Disord 29:413-23. 2010..To investigate associations of the Mediterranean diet (MeDi) components and the MeDi score with mild cognitive impairment (MCI)... - Cardiac disease associated with increased risk of nonamnestic cognitive impairment: stronger effect on womenRosebud O Roberts
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
JAMA Neurol 70:374-82. 2013..Nonamnestic mild cognitive impairment, a putative precursor of vascular and other non-Alzheimer dementias, is hypothesized to have a vascular etiology... - Association of C-reactive protein with mild cognitive impairmentRosebud O Roberts
Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, MN, USA
Alzheimers Dement 5:398-405. 2009..This study examined the association of inflammatory markers in serum or plasma with prevalent MCI and MCI subtypes in a population-based sample... - Relative intake of macronutrients impacts risk of mild cognitive impairment or dementiaRosebud O Roberts
Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
J Alzheimers Dis 32:329-39. 2012..52-1.20]; p for trend = 0.03) in the fully adjusted models. A dietary pattern with relatively high caloric intake from carbohydrates and low caloric intake from fat and proteins may increase the risk of MCI or dementia in elderly persons... - Association of prior stroke with cognitive function and cognitive impairment: a population-based studyDavid S Knopman
Department of Neurology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
Arch Neurol 66:614-9. 2009..Defining the nature of the contribution of stroke to cognitive impairment remains challenging... - Long-term risk of depressive and anxiety symptoms after early bilateral oophorectomyWalter A Rocca
Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Menopause 15:1050-9. 2008..We studied the long-term risk of depressive and anxiety symptoms in women who underwent bilateral oophorectomy before menopause... - The influence of apolipoprotein E genotype on visuospatial attention dissipates after age 80Selam Negash
Department of Neurology, Mayo Clinic, USA
Neuropsychology 23:81-9. 2009..The dissipation of the APOE effect in old-old individuals at lower risk of AD suggests that visuospatial attention impairments seen as early as midlife in APOE-e4 carriers may be a preclinical marker of AD... - Polyunsaturated fatty acids and reduced odds of MCI: the Mayo Clinic Study of AgingRosebud O Roberts
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
J Alzheimers Dis 21:853-65. 2010..In this study, higher intake of PUFA and MUFA was associated with a reduced likelihood of MCI among elderly persons in the population-based setting... - Successful aging: definitions and prediction of longevity and conversion to mild cognitive impairmentSelam Negash
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Am J Geriatr Psychiatry 19:581-8. 2011..To examine alternative models of defining and characterizing successful aging. Design: A retrospective cohort study... - Association of duration and severity of diabetes mellitus with mild cognitive impairmentRosebud O Roberts
Department of Health Sciences Research, Division of Epidemiology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Arch Neurol 65:1066-73. 2008..It remains unknown whether diabetes mellitus (DM) is a risk factor for mild cognitive impairment (MCI)... - Indicators of amyloid burden in a population-based study of cognitively normal elderlyMichelle M Mielke
Division of Epidemiology, College of Medicine, Mayo Clinic, Rochester, MN, USA
Neurology 79:1570-7. 2012..The identification of inexpensive and noninvasive screening variables that can identify individuals who have significant amyloid accumulation would reduce screening costs... - Anxious personality predicts an increased risk of Parkinson's diseaseJames H Bower
Department of Neurology, College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Mov Disord 25:2105-13. 2010..Our long-term historical cohort study suggests that an anxious personality trait may predict an increased risk of PD developing many years later... - Effects of ApoE genotype and mild cognitive impairment on implicit learningSelam Negash
Mayo Clinic, Rochester, MN 55905, USA
Neurobiol Aging 28:885-93. 2007.... - Comparison of the short test of mental status and the mini-mental state examination in mild cognitive impairmentDavid F Tang-Wai
Department of Neurology, the Mayo Alzheimer's Disease Research Center, Mayo Clinic, Rochester, Minn. 55905, USA
Arch Neurol 60:1777-81. 2003.... - Coronary heart disease is associated with non-amnestic mild cognitive impairmentRosebud O Roberts
Mayo Clinic, Department of Health Sciences Research, Division of Epidemiology, 200 First Street SW, Rochester, MN 55905, United States
Neurobiol Aging 31:1894-902. 2010..75; 95% CI=1.28-2.41), but not with na-MCI (OR=1.17; 95% CI=0.69-2.00). The association of CHD with prevalent na-MCI but not with a-MCI suggests that CHD and na-MCI may have similar underlying etiologies... - Physical exercise as a preventive or disease-modifying treatment of dementia and brain agingJ Eric Ahlskog
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Mayo Clin Proc 86:876-84. 2011..Exercise should not be overlooked as an important therapeutic strategy... - Long-term effects of bilateral oophorectomy on brain aging: unanswered questions from the Mayo Clinic Cohort Study of Oophorectomy and AgingWalter A Rocca
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Womens Health (Lond Engl) 5:39-48. 2009..Results from other studies are cited as evidence for or against each possible mechanism. These putative causal mechanisms are probably intertwined, and their clarification is a research priority... - Metabolic syndrome, inflammation, and nonamnestic mild cognitive impairment in older persons: a population-based studyRosebud O Roberts
Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
Alzheimer Dis Assoc Disord 24:11-8. 2010..31; 95% CI=1.07, 5.00), but not with a-MCI (OR=0.96; 95% CI=0.59, 1.54). The combined presence of MetS and high levels of inflammation is associated with na-MCI in this elderly cohort, and suggests etiologic differences in MCI subtypes... - Validation of the telephone interview for cognitive status-modified in subjects with normal cognition, mild cognitive impairment, or dementiaDavid S Knopman
Department of Neurology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Neuroepidemiology 34:34-42. 2010..The telephone assessment of cognitive functions may reduce the cost and burden of epidemiological studies... - Probable rapid eye movement sleep behavior disorder increases risk for mild cognitive impairment and Parkinson disease: a population-based studyBrendon P Boot
Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Ann Neurol 71:49-56. 2012..There are no data on such risks in a population-based sample... - Mild cognitive impairment: ten years laterRonald C Petersen
Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Arch Neurol 66:1447-55. 2009..This review summarizes the progress that has been made while also recognizing the challenges that remain... - Argyrophilic grains: a distinct disease or an additive pathology?Keith A Josephs
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Neurobiol Aging 29:566-73. 2008..Argyrophilic grains (AG) are silver-positive spindle-shaped lesions found at postmortem. Their significance is controversial... - Pessimistic, anxious, and depressive personality traits predict all-cause mortality: the Mayo Clinic cohort study of personality and agingBrandon R Grossardt
Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Psychosom Med 71:491-500. 2009..To study the association between several personality traits and all-cause mortality... - Argyrophilic grain disease in demented subjects presenting initially with amnestic mild cognitive impairmentGregory A Jicha
Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
J Neuropathol Exp Neurol 65:602-9. 2006..AGD is a common pathologic finding in subjects who have been diagnosed with amnestic MCI... - A collaborative study of the emergence and clinical features of the major depressive syndrome of Alzheimer's diseaseGeorge S Zubenko
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Room E1230, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Am J Psychiatry 160:857-66. 2003.... - Neuropsychiatric aspects of primary progressive aphasiaYasaman Fatemi
Mayo Clinic College of Medicine, Rochester, MN Northwestern University, Evanston, IL Charles University Faculty of Medicine, Hradec Kralove, Czech Republic
J Neuropsychiatry Clin Neurosci 23:168-72. 2011..Depression, apathy, agitation, anxiety, appetite change, and irritability are associated with PPA. Hallucinations, delusions, and night-time behavior were not associated with PPA... - Longitudinal stability of subsyndromal symptoms of depression in individuals with mild cognitive impairment: relationship to conversion to dementia after 3 yearsR Scott Mackin
Department of Psychiatry, University of California, San Francisco, CA, USA
Int J Geriatr Psychiatry 27:355-63. 2012..To evaluate the degree to which longitudinal stability of subsyndromal symptoms of depression (SSD) is associated with conversion to dementia in patients with mild cognitive impairment (MCI)... - Frontotemporal dementia and parkinsonism associated with the IVS1+1G->A mutation in progranulin: a clinicopathologic studyBradley F Boeve
Department of Neurology, Mayo Clinic Rochester, MN 55905, USA
Brain 129:3103-14. 2006..These findings suggest that the insR352 PSEN1 is not pathogenic, and the IVS1+1G-->A mutation in PGRN causes FTDP associated with FTLD-U pathology and represents a new class of neurodegenerative disease--the 'hypoprogranulinopathies'... - Increased risk of depressive and anxiety disorders in relatives of patients with Parkinson diseaseGennarina Arabia
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Arch Gen Psychiatry 64:1385-92. 2007..Relatives of patients with Parkinson disease (PD) have an increased risk of PD and other neurologic disorders; however, their risk of psychiatric disorders remains uncertain... - Untreated type 2 diabetes and its complications are associated with subcortical infarctionsRosebud O Roberts
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA
Diabetes Care 34:184-6. 2011..To investigate the association of type 2 diabetes with subcortical infarctions... - Pathological gambling caused by drugs used to treat Parkinson diseaseM Leann Dodd
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
Arch Neurol 62:1377-81. 2005..Pathological gambling is a rare potential complication related to treatment of Parkinson disease (PD). However, the etiology of this behavior is poorly understood... - Functional movement disorders: successful treatment with a physical therapy rehabilitation protocolKathrin Czarnecki
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
Parkinsonism Relat Disord 18:247-51. 2012..Functional ("psychogenic") gait and other movement disorders have proven very difficult to treat... - Pharmacogenomic implications of variants of monoaminergic-related genes in geriatric psychiatryPaulo R Shiroma
Geriatric Psychiatry Clinic, Mental Health Service Line, Minneapolis VA Medical Center, University of Minnesota Medical School, Minneapolis, MN, USA
Pharmacogenomics 11:1305-30. 2010..A multicenter collaborative research effort would be an effective strategy to increase sample sizes to further investigate how gene variants impact the pharmacodynamics and pharmacokinetics of psychotropic drugs in elderly persons... - Teaching motivational interviewing to first-year medical students to improve counseling skills in health behavior changeMaria K Poirier
Division of General Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 79:327-31. 2004..To examine the effectiveness of motivational interviewing training on improving medical students' knowledge of and confidence in their ability to counsel patients regarding health behavior change... - Delirium resulting from paraneoplastic limbic encephalitis caused by Hodgkin's diseaseSimon Kung
Department of Psychology and Psychiatry, Mayo Clinic, Rochester, MN 55905, USA
Psychosomatics 43:498-501. 2002 - Perspectives on depression, mild cognitive impairment, and cognitive declineDavid C Steffens
Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC 27710, USA
Arch Gen Psychiatry 63:130-8. 2006....
Research Grants
- Psychiatric Characterization/Mild Cognitive ImpairmentYonas Geda; Fiscal Year: 2006..In summary, the research project and the educational activities of the K award will lay down the foundation for the candidate to become an independent investigator in the gray zone between aging and dementia. ..