Fernando C Fervenza

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. ncbi request reprint Henoch-Schönlein purpura nephritis
    Fernando C Fervenza
    Division of Nephrology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Dermatol 42:170-7. 2003
  2. doi request reprint Idiopathic membranous nephropathy: diagnosis and treatment
    Fernando C Fervenza
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 First Street, SW, Rochester, MN 55905, USA
    Clin J Am Soc Nephrol 3:905-19. 2008
  3. pmc American Society of Nephrology Quiz and Questionnaire 2012: glomerulonephritis
    Fernando C Fervenza
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Clin J Am Soc Nephrol 8:1460-5. 2013
  4. ncbi request reprint Acute granulomatous interstitial nephritis and colitis in anticonvulsant hypersensitivity syndrome associated with lamotrigine treatment
    F C Fervenza
    Division of Nephrology, Baylor University Medical Center, Dallas, TX, USA
    Am J Kidney Dis 36:1034-40. 2000
  5. doi request reprint Rituximab in ANCA-associated vasculitis: fad or fact?
    Fernando C Fervenza
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN 55901, USA
    Nephron Clin Pract 118:c182-8; discussion c188. 2011
  6. pmc Rituximab therapy in idiopathic membranous nephropathy: a 2-year study
    Fernando C Fervenza
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN 55901, USA
    Clin J Am Soc Nephrol 5:2188-98. 2010
  7. pmc Induction of heme oxygenase-1 and ferritin in the kidney in warm antibody hemolytic anemia
    Fernando C Fervenza
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA
    Am J Kidney Dis 52:972-7. 2008
  8. ncbi request reprint Fabry disease: an underrecognized cause of proteinuria
    F C Fervenza
    Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA
    Kidney Int 73:1193-9. 2008
  9. ncbi request reprint Rituximab treatment of idiopathic membranous nephropathy
    F C Fervenza
    Division of Nephrology and Hypertension, Mayo Clinic, 200 First Street SW, Rochester, MN 55901, USA
    Kidney Int 73:117-25. 2008
  10. ncbi request reprint Acute rapamycin nephrotoxicity in native kidneys of patients with chronic glomerulopathies
    Fernando C Fervenza
    Division of Nephrology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Nephrol Dial Transplant 19:1288-92. 2004

Detail Information

Publications71

  1. ncbi request reprint Henoch-Schönlein purpura nephritis
    Fernando C Fervenza
    Division of Nephrology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Dermatol 42:170-7. 2003
  2. doi request reprint Idiopathic membranous nephropathy: diagnosis and treatment
    Fernando C Fervenza
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 First Street, SW, Rochester, MN 55905, USA
    Clin J Am Soc Nephrol 3:905-19. 2008
    ....
  3. pmc American Society of Nephrology Quiz and Questionnaire 2012: glomerulonephritis
    Fernando C Fervenza
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Clin J Am Soc Nephrol 8:1460-5. 2013
    ..This article recapitulates the session and reproduces its educational value for a larger audience--that of the readers of the Clinical Journal of the American Society of Nephrology. Have fun...
  4. ncbi request reprint Acute granulomatous interstitial nephritis and colitis in anticonvulsant hypersensitivity syndrome associated with lamotrigine treatment
    F C Fervenza
    Division of Nephrology, Baylor University Medical Center, Dallas, TX, USA
    Am J Kidney Dis 36:1034-40. 2000
    ....
  5. doi request reprint Rituximab in ANCA-associated vasculitis: fad or fact?
    Fernando C Fervenza
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN 55901, USA
    Nephron Clin Pract 118:c182-8; discussion c188. 2011
    ..Two studies, recently published in the New England Journal of Medicine, have examined the efficacy of RTX in inducing remission in patients with severe AAV...
  6. pmc Rituximab therapy in idiopathic membranous nephropathy: a 2-year study
    Fernando C Fervenza
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN 55901, USA
    Clin J Am Soc Nephrol 5:2188-98. 2010
    ..This hypothesis was supported by previous pharmacokinetic (PK) analysis showing that RTX levels in the two-dose regimen were 50% lower compared with nonproteinuric patients, which could potentially result in undertreatment...
  7. pmc Induction of heme oxygenase-1 and ferritin in the kidney in warm antibody hemolytic anemia
    Fernando C Fervenza
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA
    Am J Kidney Dis 52:972-7. 2008
    ..Finally, this case report documents that nephrotic-range proteinuria can occur in patients with autoimmune hemolytic anemia complicated by hemoglobinuria...
  8. ncbi request reprint Fabry disease: an underrecognized cause of proteinuria
    F C Fervenza
    Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA
    Kidney Int 73:1193-9. 2008
  9. ncbi request reprint Rituximab treatment of idiopathic membranous nephropathy
    F C Fervenza
    Division of Nephrology and Hypertension, Mayo Clinic, 200 First Street SW, Rochester, MN 55901, USA
    Kidney Int 73:117-25. 2008
    ..Rituximab appears effective in reducing proteinuria in some patients with idiopathic membranous nephropathy but prospective identification of responsive patients was not possible...
  10. ncbi request reprint Acute rapamycin nephrotoxicity in native kidneys of patients with chronic glomerulopathies
    Fernando C Fervenza
    Division of Nephrology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Nephrol Dial Transplant 19:1288-92. 2004
    ..However, we call attention to the potential toxicity associated with the use of rapamycin in this setting...
  11. ncbi request reprint C3 glomerulonephritis: clinicopathological findings, complement abnormalities, glomerular proteomic profile, treatment, and follow-up
    Sanjeev Sethi
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Kidney Int 82:465-73. 2012
    ..Thus, C3GN results from diverse abnormalities of the alternative complement pathway leading to subsequent glomerular injury...
  12. pmc Laser microdissection and proteomic analysis of amyloidosis, cryoglobulinemic GN, fibrillary GN, and immunotactoid glomerulopathy
    Sanjeev Sethi
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Clin J Am Soc Nephrol 8:915-21. 2013
    ..Organized deposits are present in amyloidosis, fibrillary GN, and immunotactoid glomerulopathy. However, the constituents of the deposits are not known...
  13. doi request reprint Clinical features of patients with immunoglobulin light chain amyloidosis (AL) with vascular-limited deposition in the kidney
    Alfonso Eirin
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA
    Nephrol Dial Transplant 27:1097-101. 2012
    ..There was a preference for λ light chain in the D-AL that was not noted in the V-AL. Patients with D-AL in this study had a longer median survival but most of them were stem cell transplantation candidates...
  14. pmc Mycophenolate mofetil for induction and maintenance of remission in microscopic polyangiitis with mild to moderate renal involvement--a prospective, open-label pilot trial
    Francisco Silva
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 First Street, SW, Rochester, MN 55905, USA
    Clin J Am Soc Nephrol 5:445-53. 2010
    ..This prospective pilot trial explored whether mycophenolate mofetil (MMF) represents an effective alternative to CYC for induction and maintenance of remission in MPA with mild to moderate renal involvement...
  15. pmc Laser microdissection and mass spectrometry-based proteomics aids the diagnosis and typing of renal amyloidosis
    Sanjeev Sethi
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Kidney Int 82:226-34. 2012
    ....
  16. doi request reprint Recurrent membranoproliferative glomerulonephritis after kidney transplantation
    Elizabeth C Lorenz
    Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Kidney Int 77:721-8. 2010
    ..Our study shows the risk of MPGN recurrence and progression depends on identifiable pretransplant characteristics, has variable clinical impact, and can result in graft failure...
  17. pmc Low- and high-molecular-weight urinary proteins as predictors of response to rituximab in patients with membranous nephropathy: a prospective study
    Maria V Irazabal
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN, USA
    Nephrol Dial Transplant 28:137-46. 2013
    ..Selective urinary biomarkers have been considered superior to total proteinuria in predicting response to treatment and outcome in patients with membranous nephropathy (MN)...
  18. pmc Urinary albumin excretion patterns of patients with cast nephropathy and other monoclonal gammopathy-related kidney diseases
    Nelson Leung
    Division of Hematology, Mayo Clinic, Rochester, Minnesota 55901, USA
    Clin J Am Soc Nephrol 7:1964-8. 2012
    ....
  19. pmc Rituximab for the treatment of Churg-Strauss syndrome with renal involvement
    Rodrigo Cartin-Ceba
    Divison of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA
    Nephrol Dial Transplant 26:2865-71. 2011
    ..We aim to evaluate the safety and efficacy of RTX in inducing remission of renal disease activity in patients with CSS...
  20. doi request reprint Long-term outcome of autologous stem cell transplantation in light chain deposition disease
    Elizabeth C Lorenz
    Division of Nephrology and Hypertension, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA
    Nephrol Dial Transplant 23:2052-7. 2008
    ..However, the impact of ASCT on renal function is unclear. This study retrospectively reviewed the effect of ASCT on renal function in patients with LCDD...
  21. ncbi request reprint Severity of baseline proteinuria predicts renal response in immunoglobulin light chain-associated amyloidosis after autologous stem cell transplantation
    Nelson Leung
    Division of Nephrology and Hypertension, Mayo Clinic Rochester, Rochester, Minnesota, USA
    Clin J Am Soc Nephrol 2:440-4. 2007
    ..Achievement of renal response was associated with improved survival. These results suggest that early intervention with aggressive therapy is not only justified but recommended to achieve optimal response...
  22. doi request reprint C3 glomerulonephritis associated with monoclonal gammopathy: a case series
    Ladan Zand
    Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA
    Am J Kidney Dis 62:506-14. 2013
    ..Functional inhibition of the complement-regulating proteins may result from a monoclonal gammopathy...
  23. pmc Proliferative glomerulonephritis with monoclonal IgG deposits recurs in the allograft
    Samih H Nasr
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Clin J Am Soc Nephrol 6:122-32. 2011
    ..Proliferative GN with monoclonal IgG deposits (PGNMID) is a newly described entity resembling immune complex GN. Its potential to recur in the allograft is undefined...
  24. doi request reprint Bleeding complications after transcutaneous kidney biopsy in patients with systemic amyloidosis: single-center experience in 101 patients
    Sandra M Soares
    Department of Internal Medicine, Mayo Clinic Rochester, Rochester, MN 55902, USA
    Am J Kidney Dis 52:1079-83. 2008
    ..Amyloidosis is thought to be 1 of the risk factors, but this has not been confirmed in a large study. We performed this study to assess the risk of bleeding after kidney biopsy in patients with amyloidosis...
  25. pmc Atypical postinfectious glomerulonephritis is associated with abnormalities in the alternative pathway of complement
    Sanjeev Sethi
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Kidney Int 83:293-9. 2013
    ..Hence, the sequela is continual glomerular deposition of complement factors with resultant inflammation and development of an 'atypical' postinfectious glomerulonephritis...
  26. doi request reprint Rituximab for remission induction and maintenance in refractory granulomatosis with polyangiitis (Wegener's): ten-year experience at a single center
    Rodrigo Cartin-Ceba
    Mayo Clinic, Rochester, Minnesota, USA
    Arthritis Rheum 64:3770-8. 2012
    ....
  27. pmc Proliferative glomerulonephritis secondary to dysfunction of the alternative pathway of complement
    Sanjeev Sethi
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Clin J Am Soc Nephrol 6:1009-17. 2011
    ..A recently described entity referred to as GN with C3 deposition (GN-C3) bears many similarities to DDD. The purpose of this study was to evaluate AP function in cases of GN-C3...
  28. doi request reprint Long-term outcomes of patients with light chain amyloidosis (AL) after renal transplantation with or without stem cell transplantation
    Sandra M S Herrmann
    Division of Nephrology and Hypertension, Mayo Clinic Rochester, Rochester, MN, USA
    Nephrol Dial Transplant 26:2032-6. 2011
    ..Kidney transplantation (KTx) has become more common but the long-term outcomes remain unknown and it is the objective of this study...
  29. doi request reprint Urine but not serum soluble urokinase receptor (suPAR) may identify cases of recurrent FSGS in kidney transplant candidates
    Carlos R Franco Palacios
    Division of Nephrology and Hypertension, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Transplantation 96:394-9. 2013
    ..It was noted to be uniquely elevated in cases of primary FSGS, with higher levels noted in cases that recurred after transplantation. It is also suggested as a possible target and marker of therapy...
  30. pmc Dense deposit disease associated with monoclonal gammopathy of undetermined significance
    Sanjeev Sethi
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Kidney Dis 56:977-82. 2010
    ..Thus, DDD in some older patients may be a distinct clinicopathologic entity that represents an uncommon complication of MGUS...
  31. pmc Renal involvement in primary Sjögren's syndrome: a clinicopathologic study
    Saugar Maripuri
    Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Clin J Am Soc Nephrol 4:1423-31. 2009
    ..Renal pathology and clinical outcomes in patients with primary Sjögren's syndrome (pSS) who underwent kidney biopsy (KB) because of renal impairment are reported...
  32. doi request reprint Long-term outcome of kidney transplantation in patients with fibrillary glomerulonephritis or monoclonal gammopathy with fibrillary deposits
    Peter G Czarnecki
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Kidney Int 75:420-7. 2009
    ..Whether the development of hematological malignancies following transplantation in this group is related to their original disease or was coincidental requires further studies...
  33. pmc Fibrillary glomerulonephritis: a report of 66 cases from a single institution
    Samih H Nasr
    Mayo Clinic, Division of Anatomic Pathology, Hilton 10 20, 200 First Street SW, Rochester, MN 55905, USA
    Clin J Am Soc Nephrol 6:775-84. 2011
    ..Most previously reported cases were idiopathic. To better define the clinical-pathologic spectrum and prognosis, we report the largest single-center series with the longest follow-up...
  34. doi request reprint Efficacy of remission-induction regimens for ANCA-associated vasculitis
    Ulrich Specks
    Mayo Clinic Foundation, Rochester, MN, USA
    N Engl J Med 369:417-27. 2013
    ....
  35. ncbi request reprint Renal transplantation in antineutrophil cytoplasmic antibody-associated vasculitis: a multicenter experience
    Duvuru Geetha
    Division of Nephrology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
    Transplantation 91:1370-5. 2011
    ..We report our experience with AAV patients who underwent KTX at our institutions between 1996 and 2010. Median follow-up was 64 months...
  36. doi request reprint Renal failure due to combined cast nephropathy, amyloidosis and light-chain deposition disease
    Elizabeth C Lorenz
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA
    Nephrol Dial Transplant 25:1340-3. 2010
    ..We report a case of renal failure in a patient with MM caused by concurrent CN, amyloidosis and LCDD which has not been previously described...
  37. pmc A patient with nephrotic-range proteinuria and focal global glomerulosclerosis
    Fernando C Fervenza
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota
    Clin J Am Soc Nephrol 8:1979-87. 2013
    ..The case illustrates the crucial role of electron microscopy as well as evaluation of the identity of the proteinuria that accompanies a biopsy finding of focal and global or focal and segmental glomerulosclerosis. ..
  38. pmc Clinical Findings, Pathology, and Outcomes of C3GN after Kidney Transplantation
    Ladan Zand
    Department of Internal Medicine, Division of Nephrology and Hypertension, and
    J Am Soc Nephrol 25:1110-7. 2014
    ..To summarize, C3GN recurs in 66.7% of patients, and one half of the patients experience graft failure caused by recurrence. ..
  39. doi request reprint Association of a novel complement factor H mutation with severe crescentic and necrotizing glomerulonephritis
    Fernando C Fervenza
    Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA
    Am J Kidney Dis 60:126-32. 2012
    ....
  40. pmc Membranoproliferative glomerulonephritis secondary to monoclonal gammopathy
    Sanjeev Sethi
    Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA
    Clin J Am Soc Nephrol 5:770-82. 2010
    ..Autoimmune diseases and chronic infections, such as hepatitis C, are commonly recognized causes of MPGN; however, monoclonal gammopathy is a less widely recognized cause of MPGN...
  41. doi request reprint Successful pregnancy and delivery of a healthy newborn despite transplacental transfer of antimyeloperoxidase antibodies from a mother with microscopic polyangiitis
    Francisco Silva
    Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Am J Kidney Dis 54:542-5. 2009
    ..No clinical manifestation of vasculitis developed in the newborn. This case supports that anti-MPO antibodies alone are not pathogenic without additional cofactors...
  42. pmc Rituximab for refractory Wegener's granulomatosis: report of a prospective, open-label pilot trial
    Karina A Keogh
    Division of Pulmonary and Critical Care Medicine, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
    Am J Respir Crit Care Med 173:180-7. 2006
    ..Their depletion has been proposed as salvage therapy for refractory disease. Earlier encouraging reports are confounded by concomitant immunosuppressive medications and include only limited available biomarker data...
  43. ncbi request reprint Acute granulomatous interstitial nephritis secondary to bisphosphonate alendronate sodium
    Lourdes Pena de la Vega
    Department of Internal Medicine, Division of Nephrology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Ren Fail 27:485-9. 2005
    ..Partial recovery of renal function occurred after 6 weeks of prednisone therapy and cyclophosphamide. This report describes a unique case of acute granulomatous interstitial nephritis and leukemic cell kidney infiltration by CLL...
  44. ncbi request reprint Changing incidence of glomerular disease in Olmsted County, Minnesota: a 30-year renal biopsy study
    Sundararaman Swaminathan
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Clin J Am Soc Nephrol 1:483-7. 2006
    ..1, 1.8, and 1.0 per 100,000/yr, respectively. This study confirms that the incidence of GN is growing overall, particularly for FSGS, which is the leading cause of nephrotic syndrome in white adults...
  45. ncbi request reprint Renal response after high-dose melphalan and stem cell transplantation is a favorable marker in patients with primary systemic amyloidosis
    Nelson Leung
    Division of Nephrology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Kidney Dis 46:270-7. 2005
    ..This study was undertaken to determine the prognostic importance of renal response after high-dose melphalan and stem cell transplantation...
  46. ncbi request reprint Recurrent Goodpasture's disease secondary to a monoclonal IgA1-kappa antibody autoreactive with the alpha1/alpha2 chains of type IV collagen
    Dorin Bogdan Borza
    Division of Nephrology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
    Am J Kidney Dis 45:397-406. 2005
    ..The specificity of an IgA antibody implicated in the pathogenesis of anti-GBM disease has been investigated for the first time, identifying the alpha1/alpha2(IV) collagen chains as a novel target for nephritogenic antibodies...
  47. pmc A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis
    Howard Trachtman
    Division of Nephrology, Department of Pediatrics, Cohen Children s Medical Center, New Hyde Park, New York, USA
    Kidney Int 79:1236-43. 2011
    ..Thus, single-dose fresolimumab was well tolerated in patients with primary resistant FSGS. Additional evaluation in a larger dose-ranging study is necessary...
  48. ncbi request reprint Acute kidney injury in patients with inactive cytochrome P450 polymorphisms
    Nelson Leung
    Mayo Clinic Rochester, Division of Nephrology and Hypertension, Rochester, Minnesota, USA
    Ren Fail 31:749-52. 2009
    ..These are the first two cases of AKI associated with non-functional polymorphisms of cytochrome P450 superfamily. While the exact mechanism has not been worked out, it introduced the possibility of a new source of kidney injury...
  49. ncbi request reprint Rituximab therapy for Type I membranoproliferative glomerulonephritis
    John J Dillon
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA
    Clin Nephrol 77:290-5. 2012
    ..It has no established treatment in adults. Our hypothesis was that this disease would respond to B cell depletion with rituximab, an anti-CD20 monoclonal antibody...
  50. doi request reprint Secondary focal and segmental glomerulosclerosis associated with single-nucleotide polymorphisms in the genes encoding complement factor H and C3
    Sanjeev Sethi
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Kidney Dis 60:316-21. 2012
    ..This case also expands the list of genetic polymorphisms that can be associated with an FSGS phenotype...
  51. doi request reprint Safety and diagnostic yield of transjugular renal biopsy
    Sanjay Misra
    Department of Radiology, Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905, USA
    J Vasc Interv Radiol 19:546-51. 2008
    ..To evaluate the safety and tissue acquisition with transjugular renal biopsy (TJRB) by using the Quick-Core method in patients who were at high risk for complications with percutaneous renal biopsy...
  52. ncbi request reprint Response of Wegener's granulomatosis to anti-CD20 chimeric monoclonal antibody therapy
    U Specks
    Division of Pulmonary and Critical Care Medicine, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Arthritis Rheum 44:2836-40. 2001
    ..This modality warrants closer examination in a carefully conducted clinical trial...
  53. doi request reprint Improvement of cast nephropathy with plasma exchange depends on the diagnosis and on reduction of serum free light chains
    N Leung
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota 55905, USA
    Kidney Int 73:1282-8. 2008
    ..We found that the relationship between renal recovery and free light chain reduction was present only in patients with biopsy proven cast nephropathy showing the importance of extracorporeal light chain removal in this disease...
  54. ncbi request reprint Microscopic polyangiitis associated with thymoma, exacerbating after thymectomy
    Joseph G Parambil
    Division of Pulmonary and Critical Care Medicine, Desk East 18, Mayo Clinic, 200 1st St SW, Rochester, MN 55905, USA
    Am J Kidney Dis 48:827-31. 2006
    ..Progressive disease seen after thymectomy in this patient has potential implications regarding the pathophysiological characteristics of microscopic polyangiitis and management of patients with this clinical association...
  55. doi request reprint Membranoproliferative glomerulonephritis associated with autoimmune diseases
    Ladan Zand
    Mayo Clinic, Rochester, MN, USA
    J Nephrol 27:165-71. 2014
    ..In summary, this study describes the clinical features, renal biopsy findings, laboratory evaluation, treatment and prognosis of MPGN associated with autoimmune diseases. ..
  56. doi request reprint Treatment of ANCA-associated vasculitis: new therapies and a look at old entities
    Ladan Zand
    Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN and Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN
    Adv Chronic Kidney Dis 21:182-93. 2014
    ..There is also accumulating evidence indicating a potential role of rituximab for maintenance therapy in AAV. In this article, we will review the evidence supporting the various treatment choices for patients with AAV. ..
  57. doi request reprint Idiopathic membranoproliferative glomerulonephritis: does it exist?
    Fernando C Fervenza
    Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA
    Nephrol Dial Transplant 27:4288-94. 2012
    ..Idiopathic MPGN remains an 'endangered species' after its separation from these known causes...
  58. pmc Membranous nephropathy: the start of a paradigm shift
    Sandra M S Herrmann
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA
    Curr Opin Nephrol Hypertens 21:203-10. 2012
    ..The purpose of this review is to highlight recent advances regarding the pathogenesis of membranous nephropathy as well as potential new therapies...
  59. doi request reprint Treatment of antineutrophil cytoplasmic antibody-associated vasculitis with rituximab
    Rodrigo Cartin-Ceba
    Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Curr Opin Rheumatol 24:15-23. 2012
    ....
  60. ncbi request reprint Long-term outcome of renal transplantation in light-chain deposition disease
    Nelson Leung
    Division of Nephrology, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Am J Kidney Dis 43:147-53. 2004
    ..A small number of kidney transplantations have been performed on LCDD patients in whom end-stage renal disease (ESRD) developed...
  61. ncbi request reprint A proliferative glomerulonephritis secondary to a monoclonal IgA
    Sandra M Soares
    Division of Nephrology and Hypertension, Mayo Clinic and Foundation, Rochester, MN, USA
    Am J Kidney Dis 47:342-9. 2006
    ..The present case suggests that monoclonal IgA deposits also can cause proliferative glomerulonephritis. However, the presence of paracrystalline deposits in association with monoclonal IgA deposits has not been described previously...
  62. ncbi request reprint Wegener's granulomatosis presenting as multiple bilateral renal masses
    Nelson Leung
    Division of Nephrology, Ei S24, Mayo Clinic Rochester, 200 First Street SW, Rochester, MN 55905, USA
    Nephrol Dial Transplant 19:984-7. 2004
  63. ncbi request reprint Successful induction of remission with rituximab for relapse of ANCA-associated vasculitis post-kidney transplant: report of two cases
    D Geetha
    Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Transplant 7:2821-5. 2007
    ..Given the substantial morbidity and adverse effects of CYC, rituximab appears to be a suitable alternative agent to treat relapses of AAV posttransplantation...
  64. doi request reprint Recurrent idiopathic membranous nephropathy: early diagnosis by protocol biopsies and treatment with anti-CD20 monoclonal antibodies
    Ziad M El-Zoghby
    Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA
    Am J Transplant 9:2800-7. 2009
    ..Protocol biopsies allow early diagnosis of subclinical recurrent MN, which is often progressive. Treatment of recurrent MN with Rituximab is promising and should be evaluated in a prospective randomized controlled trial...
  65. doi request reprint Rituximab-based novel strategies for the treatment of immune-mediated glomerular diseases
    Andrea G Kattah
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA
    Autoimmun Rev 12:854-9. 2013
    ..Given its efficacy, tolerability and safety profile in comparison to more conventional treatment regimens, RTX is rapidly emerging as a critical treatment modality in glomerular disease...
  66. doi request reprint IgG4-related tubulointerstitial nephritis with membranous nephropathy
    Fernando C Fervenza
    Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA
    Am J Kidney Dis 58:320-4. 2011
    ..It is important to correctly diagnose IgG4-related TIN and concurrent membranous nephropathy because the lesion responds well to steroid therapy...
  67. ncbi request reprint A novel alpha-galactosidase a mutant (M42L) identified in a renal variant of Fabry disease
    David Rosenthal
    Department of Medicine, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Am J Kidney Dis 44:e85-9. 2004
    ..Because treatment for Fabry disease recently has become available, it is important for clinicians to be aware of this disease and pursue the diagnosis in cases of otherwise unexplained renal dysfunction...
  68. ncbi request reprint Pathology of Renal Diseases Associated with Dysfunction of the Alternative Pathway of Complement: C3 Glomerulopathy and Atypical Hemolytic Uremic Syndrome (aHUS)
    Sanjeev Sethi
    Division of Anatomic Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota
    Semin Thromb Hemost 40:416-21. 2014
    ....
  69. ncbi request reprint Membranoproliferative glomerulonephritis: pathogenetic heterogeneity and proposal for a new classification
    Sanjeev Sethi
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Semin Nephrol 31:341-8. 2011
    ..Initial AP screening tests should include serum membrane attack complex levels, an AP functional assay, and a hemolytic assay, followed by tests for mutations and autoantibodies to complement-regulating proteins...
  70. doi request reprint Recurrent idiopathic membranous nephropathy after kidney transplantation: a surveillance biopsy study
    T S Dabade
    Mayo Clinic Medical School, Mayo Clinic College of Medicine, Rochester, MN, USA
    Am J Transplant 8:1318-22. 2008
    ..In conclusion, idiopathic MN recurred in 42% of patients after transplantation. The initial clinical and histologic manifestations are subtle but the disease is progressive...
  71. ncbi request reprint Recurrence of ANCA-associated vasculitis following renal transplantation in the modern era of immunosupression
    M Gera
    Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Kidney Int 71:1296-301. 2007
    ..Potent antirejection regimes are well tolerated in these patients, are associated with a low risk of recurrence and an absence of AAV-related graft dysfunction...