Research Topics
| V G EvidenteSummaryAffiliation: Mayo Clinic Country: USA Publications
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Detail Information
Publications
Zolpidem improves dystonia in "Lubag" or X-linked dystonia-parkinsonism syndromeVirgilio Gerald H Evidente
Department of Neurology, Mayo Clinic, Scottsdale, AZ 85259, USA
Neurology 58:662-3. 2002
First case of X-linked dystonia-parkinsonism ("Lubag") to demonstrate a response to bilateral pallidal stimulationVirgilio Gerald H Evidente
Department of Neurology, Mayo Clinic, Scottsdale, Arizona 85259, USA
Mov Disord 22:1790-3. 2007..Bilateral pallidal DBS may be a viable option for Lubag patients with medically refractory symptoms...
Differentiating Parkinson's disease from other parkinsonian disordersMaria V Alvarez
Parkinson s Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, Arizona, USA
Semin Neurol 27:356-62. 2007..In this article, we present some useful clinical pearls in distinguishing idiopathic PD from atypical parkinsonism or drug-induced parkinsonism...
Piribedil for restless legs syndrome: a pilot studyV G Evidente
St Luke s Philippine Movement Disorders Center, St Luke s Medical Center, Quezon City, Philippines
Mov Disord 16:579-81. 2001..6%). This pilot study suggests that piribedil is effective for RLS...
Medication dose reductions after pallidal versus subthalamic stimulation in patients with Parkinson's diseaseV G H Evidente
Department of Neurology Department of Neurological Surgery, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA
Acta Neurol Scand 124:211-4. 2011..To compare the medication dose reduction between deep brain stimulation (DBS) of the globus pallidus interna (GPi) vs subthalamic nucleus (STN) in matched patients with Parkinson's disease (PD)...
An update on the neurologic applications of botulinum toxinsVirgilio Gerald H Evidente
Department of Neurology, Mayo Clinic Arizona, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA
Curr Neurol Neurosci Rep 10:338-44. 2010..This article highlights some of the common neurologic conditions currently improved by botulinum toxins and reviews the scientific evidence from research studies and clinical experience with these conditions...
Neuropathological findings of PSP in the elderly without clinical PSP: possible incidental PSP?Virgilio Gerald H Evidente
Department of Neurology, Mayo Clinic, 13400 E Shea Blvd, Scottsdale, AZ 85259, USA
Parkinsonism Relat Disord 17:365-71. 2011..We aimed to describe cases with incidental neuropathological findings of progressive supranuclear palsy (PSP) from the Banner Sun Health Research Institute Brain and Body Donation Program...
Phenotypic and molecular analyses of X-linked dystonia-parkinsonism ("lubag") in womenVirgilio Gerald H Evidente
Department of Neurology, Mayo Clinic, 13400 E Shea Boulevard, Scottsdale, AZ 85259, USA
Arch Neurol 61:1956-9. 2004..Genetic confirmation is performed through haplotyping or detection of disease-specific changes in the DYT3 gene...
Smell testing is abnormal in 'lubag' or X-linked dystonia-parkinsonism: a pilot studyVirgilio Gerald H Evidente
Department of Neurology, Mayo Clinic, 13400 E Shea Boulevard, Scottsdale, AZ 85259, USA
Parkinsonism Relat Disord 10:407-10. 2004..Nine of 20 Lubag patients (45%) had ccUPSIT scores below the mean, with the lowest score being 11. This pilot study suggests that olfactory dysfunction may occur in Lubag patients...
X-linked dystonia ("Lubag") presenting predominantly with parkinsonism: a more benign phenotype?Virgilio Gerald H Evidente
Department of Neurology, Mayo Clinic Scottsdale, Scottsdale, Arizona 85259, USA
Mov Disord 17:200-2. 2002..We report on three cases of Lubag presenting with isolated parkinsonism without dystonia or late-onset dystonia and a slower course...
Piribedil as an adjunct to levodopa in advanced Parkinson's disease: the Asian experienceVirgilio Gerald H Evidente
Department of Neurology, Mayo Clinic, 13400 E Shea Blvd, Scottsdale, AZ 85259, USA
Parkinsonism Relat Disord 10:117-21. 2003..Most common side effects were hallucinations (20%), dyskinesias (20%), dizziness (8%), and sleepiness (6%). This trial shows that piribedil is effective and well-tolerated by Asian patients with advanced PD at least with short-term use...
Phenomenology of "Lubag" or X-linked dystonia-parkinsonismVirgilio Gerald H Evidente
Department of Neurology, Mayo Clinic, Scottsdale, Arizona 85259, USA
Mov Disord 17:1271-7. 2002..Thus, it is imperative to elicit an exhaustive family history in any Filipino male adult who presents with a movement disorder...
Serum leptin concentrations and satiety in Parkinson's disease patients with and without weight lossV G Evidente
Mayo Clinic Scottsdale, Scottsdale, Arizona 85259, USA
Mov Disord 16:924-7. 2001..The results indicate that unintended weight loss in PD patients is unlikely to be due to abnormal serum leptin concentrations...
Both early and late cognitive dysfunction affects the electroencephalogram in Parkinson's diseaseJ N Caviness
Department of Neurology, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ, USA
Parkinsonism Relat Disord 13:348-54. 2007..PD-MCI has mean quantitative EEG characteristics that represent an intermediate electrophysiological state between PD-CogNL and PD-D...
Long-term follow-up of deep brain stimulation for Meige syndromeMark K Lyons
Department of Neurological Surgery, Mayo Clinic Arizona, Phoenix, Arizona 85054, USA
Neurosurg Focus 29:E5. 2010..While the etiology for this disorder is unknown, it is considered by many investigators to be a form of idiopathic torsion dystonia. Pallidal stimulation is widely considered to be effective for dystonia...
Defining mild cognitive impairment in Parkinson's diseaseJohn N Caviness
Department of Neurology, Mayo Clinic, Scottsdale, Arizona, USA
Mov Disord 22:1272-7. 2007..Defining PD-MCI offers an opportunity for further study of cognitive impairment in PD and targets for earlier therapeutic intervention...
Responsiveness of short-lasting unilateral neuralgiform headache with conjunctival injection and tearing to hypothalamic deep brain stimulationMark K Lyons
Department of Neurological Surgery, Mayo Clinic Arizona, Pheonix, Arizona 85054, USA
J Neurosurg 110:279-81. 2009..The authors report on a case of SUNCT syndrome successfully treated with hypothalamic deep brain stimulation and discuss the current literature...
Case studies in movement disordersVirgilio Gerald H Evidente
Movement Disorders Division, Department of Neurology, Mayo Clinic, Scottsdale, Arizona 85259, USA
Semin Neurol 23:277-84. 2003..A detailed discussion of botulinum toxin follows the case on cervical dystonia, focusing on its mechanism of action, clinical indications, side effects, and dosing...
Restless legs syndrome in Parkinson's disease patients may improve with subthalamic stimulationErika Driver-Dunckley
Department of Neurology, Mayo Clinic Scottsdale, Scottsdale, Arizona, USA
Mov Disord 21:1287-9. 2006..Despite a mean 56% decrease in their levodopa equivalents postoperatively, their RLS scores dropped by a mean of 84% (100% in three). Our findings suggest that bilateral STN DBS surgery can improve RLS in patients with advanced PD...
Persistent chorea triggered by hyperglycemic crisis in diabeticsJ E Ahlskog
Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, USA
Mov Disord 16:890-8. 2001..Most previously described cases have involved a reversible clinical syndrome, in contrast to our patients. The pathogenic mechanisms remain uncertain...
Understanding drug-induced parkinsonism: separating pearls from oy-stersMaria Victoria G Alvarez
Mayo Clinic Arizona, 13400 Shea Blvd, Scottsdale, AZ 85259, USA
Neurology 70:e32-4. 2008
Case series of painful legs and moving toes: clinical and electrophysiologic observationsMaria V Alvarez
Department of Neurology, Mayo Clinic, Scottsdale, Arizona 85259, USA
Mov Disord 23:2062-6. 2008..Movements were partially suppressible and were diminished but still apparent during light sleep. GABAergic agents were most effective in controlling the pain and the movements...
Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental central nervous system phenotypesMichael F Waters
Division of Neurology and Rose Moss Laboratory for Parkinson s and Neurodegenerative Diseases, Burns and Allen Research Institute, Cedars Sinai Medical Center, Los Angeles, California, 90048 USA
Nat Genet 38:447-51. 2006..Our results establish a role for KCNC3 in phenotypes ranging from developmental disorders to adult-onset neurodegeneration and suggest voltage-gated K+ channels as candidates for additional neurodegenerative diseases...
Limb cooling and focal dystoniaVirgilio Gerald H Evidente
Mov Disord 19:238. 2004
