PETER DYCK

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. pmc Impaired glycemia and diabetic polyneuropathy: the OC IG Survey
    Peter J Dyck
    Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
    Diabetes Care 35:584-91. 2012
  2. pmc Modeling nerve conduction criteria for diagnosis of diabetic polyneuropathy
    Peter J Dyck
    Peripheral Neuropathy Research Laboratory, Department of Neurology Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 44:340-5. 2011
  3. pmc Signs and symptoms versus nerve conduction studies to diagnose diabetic sensorimotor polyneuropathy: Cl vs. NPhys trial
    Peter J Dyck
    Peripheral Neuropathy Research Laboratory, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 42:157-64. 2010
  4. ncbi request reprint Does impaired glucose metabolism cause polyneuropathy? Review of previous studies and design of a prospective controlled population-based study
    Peter J Dyck
    Peripheral Neuropathy Research Laboratory, Mayo Clinic, Rochester, MN 55905, USA
    Muscle Nerve 36:536-41. 2007
  5. ncbi request reprint Challenges in design of multicenter trials: end points assessed longitudinally for change and monotonicity
    Peter J Dyck
    Peripheral Neuropathy Research Laboratories, Mayo Clinic College of Medicine, 200 First St, SW, Rochester, MN 55905, USA
    Diabetes Care 30:2619-25. 2007
  6. ncbi request reprint Modeling chronic glycemic exposure variables as correlates and predictors of microvascular complications of diabetes
    Peter J Dyck
    Mayo Clinic College of Medicine, Department of Neurology, 200 First St SW, Rochester, MN 55905, USA
    Diabetes Care 29:2282-8. 2006
  7. ncbi request reprint Monotonicity of nerve tests in diabetes: subclinical nerve dysfunction precedes diagnosis of polyneuropathy
    Peter J Dyck
    Department of Neurology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA
    Diabetes Care 28:2192-200. 2005
  8. ncbi request reprint History of standard scoring, notation, and summation of neuromuscular signs. A current survey and recommendation
    Peter J Dyck
    Department of Neurology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    J Peripher Nerv Syst 10:158-73. 2005
  9. ncbi request reprint Quantitative sensation testing in small-diameter sensory fiber neuropathy
    Peter J Dyck
    Peripheral Neuropathy Research Center, Department of Neurology, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 26:595-6. 2002
  10. ncbi request reprint Individual attributes versus composite scores of nerve conduction abnormality: sensitivity, reproducibility, and concordance with impairment
    Peter J Dyck
    Peripheral Neuropathy Research Laboratory, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, MN 55905, USA
    Muscle Nerve 27:202-10. 2003

Research Grants

  1. DIABETIC NEUROPATHY STUDY
    PETER DYCK; Fiscal Year: 2007
  2. DIABETIC NEUROPATHY STUDY
    PETER DYCK; Fiscal Year: 2003

Detail Information

Publications32

  1. pmc Impaired glycemia and diabetic polyneuropathy: the OC IG Survey
    Peter J Dyck
    Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
    Diabetes Care 35:584-91. 2012
    ....
  2. pmc Modeling nerve conduction criteria for diagnosis of diabetic polyneuropathy
    Peter J Dyck
    Peripheral Neuropathy Research Laboratory, Department of Neurology Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 44:340-5. 2011
    ..In this study we aimed to determine which criteria are valid for nerve conduction (NC) diagnosis of typical diabetic sensorimotor polyneuropathy (DSPN)...
  3. pmc Signs and symptoms versus nerve conduction studies to diagnose diabetic sensorimotor polyneuropathy: Cl vs. NPhys trial
    Peter J Dyck
    Peripheral Neuropathy Research Laboratory, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 42:157-64. 2010
    ..Study physician dx from signs and symptoms were excessively variable, often overestimating DSPN. Specific approaches to improving clinical proficiency should be tested...
  4. ncbi request reprint Does impaired glucose metabolism cause polyneuropathy? Review of previous studies and design of a prospective controlled population-based study
    Peter J Dyck
    Peripheral Neuropathy Research Laboratory, Mayo Clinic, Rochester, MN 55905, USA
    Muscle Nerve 36:536-41. 2007
    ..Here we review previous studies, list the reasons that the issue needs further study, and outline a study now in progress to address the question more definitively...
  5. ncbi request reprint Challenges in design of multicenter trials: end points assessed longitudinally for change and monotonicity
    Peter J Dyck
    Peripheral Neuropathy Research Laboratories, Mayo Clinic College of Medicine, 200 First St, SW, Rochester, MN 55905, USA
    Diabetes Care 30:2619-25. 2007
    ..Assessing clinimetric performance of diabetic sensorimotor polyneuropathy (DSPN) end points in single and multicenter trials...
  6. ncbi request reprint Modeling chronic glycemic exposure variables as correlates and predictors of microvascular complications of diabetes
    Peter J Dyck
    Mayo Clinic College of Medicine, Department of Neurology, 200 First St SW, Rochester, MN 55905, USA
    Diabetes Care 29:2282-8. 2006
    ..Specifically, we test whether combinations of components correlate and predict complications better than individual components...
  7. ncbi request reprint Monotonicity of nerve tests in diabetes: subclinical nerve dysfunction precedes diagnosis of polyneuropathy
    Peter J Dyck
    Department of Neurology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA
    Diabetes Care 28:2192-200. 2005
    ..The objective of this study was to test whether monotone worsening of nerve function, attributable to diabetes, can be demonstrated before criteria for diabetic sensorimotor polyneuropathy (DSPN) have been met. Which nerve tests are best?..
  8. ncbi request reprint History of standard scoring, notation, and summation of neuromuscular signs. A current survey and recommendation
    Peter J Dyck
    Department of Neurology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    J Peripher Nerv Syst 10:158-73. 2005
    ..representing increasing impairment based on the judgment of percentage abnormality with corrections made for age, sex, physical fitness, and physical characteristics...
  9. ncbi request reprint Quantitative sensation testing in small-diameter sensory fiber neuropathy
    Peter J Dyck
    Peripheral Neuropathy Research Center, Department of Neurology, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 26:595-6. 2002
  10. ncbi request reprint Individual attributes versus composite scores of nerve conduction abnormality: sensitivity, reproducibility, and concordance with impairment
    Peter J Dyck
    Peripheral Neuropathy Research Laboratory, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, MN 55905, USA
    Muscle Nerve 27:202-10. 2003
    ..We conclude that, with the availability of microprocessors and normative databases, electromyographers may increasingly seek to express nerve conduction abnormality also as composite scores of individual or several nerves...
  11. ncbi request reprint Clinical versus quantitative vibration assessment: improving clinical performance
    Ted M Burns
    Department of Neurology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    J Peripher Nerv Syst 7:112-7. 2002
    ..Applying some useful approaches to quantitative sensory testing might improve the accuracy of clinical sensory testing...
  12. doi request reprint Inflammatory pseudotumor of nerve: clinicopathological characteristics and a potential therapy
    Michelle L Mauermann
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    J Peripher Nerv Syst 15:216-26. 2010
    ..The primary pathophysiology is unknown but the inflammation and response to treatment suggests that there may be an immune component...
  13. pmc Mass spectrometric-based proteomic analysis of amyloid neuropathy type in nerve tissue
    Christopher J Klein
    Department of Neurology Peripheral Nerve Laboratory, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Arch Neurol 68:195-9. 2011
    ..To determine the specific type of amyloid from nerve biopsies using laser microdissection (LMD) and mass spectrometric (MS)-based proteomic analysis...
  14. pmc SEPT9 mutations and a conserved 17q25 sequence in sporadic and hereditary brachial plexus neuropathy
    Christopher J Klein
    Peripheral Neuropathy Research Laboratory, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Arch Neurol 66:238-43. 2009
    ..These mutations were not found in North American kindreds with H-BPN with a conserved 500-kilobase sequence of DNA at the 17q25 chromosomal region (where SEPT9 localizes) where a founder mutation has been suggested...
  15. ncbi request reprint Autonomic symptoms and diabetic neuropathy: a population-based study
    Phillip A Low
    Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Diabetes Care 27:2942-7. 2004
    ....
  16. ncbi request reprint The Paclitaxel acute pain syndrome: sensitization of nociceptors as the putative mechanism
    Charles L Loprinzi
    Division of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN, USA
    Cancer J 13:399-403. 2007
    ..Herein, we characterize the clinical characteristics of this syndrome using detailed patient interviews and consider the putative mechanism(s) for these symptoms...
  17. ncbi request reprint Genetic testing in inherited peripheral neuropathies
    Christopher J Klein
    Peripheral Neuropathy Research Laboratory, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Peripher Nerv Syst 10:77-84. 2005
  18. ncbi request reprint Adult polyglucosan body disease: case description of an expanding genetic and clinical syndrome
    Christopher J Klein
    Department of Neurology, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 29:323-8. 2004
    ..These findings expand the clinical and genetic spectrum of APBD. Factors other than mutation of the expressed GBE gene may cause enzyme deficiency and varied expression and development of APBD...
  19. pmc Quantitative sensation and autonomic test abnormalities in transthyretin amyloidosis polyneuropathy
    Dong Hwee Kim
    Peripheral Neuropathy Research Laboratory, Mayo Clinic, Rochester, Minnesota, USA
    Muscle Nerve 40:363-70. 2009
    ..This study provides a rationale for the use of QAT, QST, and Sigma5 NC nds as standard, objective, and quantitative measures for assessing the severity of TTR-A-PN in epidemiologic surveys, therapeutic trials, and medical practice...
  20. ncbi request reprint A 46-year-old man with numbness and shock-like sensations in hands, feet, and jaw
    David W Polston
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Lancet Neurol 3:63-7. 2004
  21. ncbi request reprint Electronic case-report forms of symptoms and impairments of peripheral neuropathy
    Peter J Dyck
    Peripheral Neuropathy Research Center, Mayo Clinic and Mayo Foundation, Rochester, MN, USA
    Can J Neurol Sci 29:258-66. 2002
    ..For the conduct of controlled clinical trials, epidemiologic surveys or even of medical practice of varieties of peripheral neuropathy, the usefulness, error rate and cost-effectiveness of scannable case-report forms has not been studied...
  22. pmc Primary amyloidosis presenting as upper limb multiple mononeuropathies
    Jennifer A Tracy
    Peripheral Neuropathy Research Laboratory, Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Muscle Nerve 41:710-5. 2010
    ..Recognition that light chain amyloidosis may be the cause of a multiple mononeuropathy pattern adds to the differential diagnosis of this clinical phenotype...
  23. ncbi request reprint Anesthesia and patients with congenital hyposensitivity to pain
    Toby N Weingarten
    Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Anesthesiology 105:338-45. 2006
    ..Sensory loss, especially that of pain, is associated with self-mutilations that may require frequent operations. Little is known about the safety of anesthesia for these patients...
  24. ncbi request reprint Effects of duration of type 2 diabetes mellitus on insulin secretion
    Farhad Zangeneh
    Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Endocr Pract 12:388-93. 2006
    ..To gain insight into the effects of duration of type 2 diabetes on insulin secretion in patients with type 2 diabetes mellitus...
  25. ncbi request reprint Microfluidic chip-based method for genotyping microsatellites, VNTRs and insertion/deletion polymorphisms
    Youvraj R Sohni
    Translational Genomics Center, Mayo Clinic, Rochester, MN 55905, USA
    Clin Biochem 36:35-40. 2003
    ..The DNA fragments are resolved clearly and the system allows quantitation. Finally, the microfluidic chip-based method may be used for both large- and small-scale genotyping studies...
  26. pmc A controlled study of medial arterial calcification of legs: implications for diabetic polyneuropathy
    Joon Shik Moon
    Peripheral Neurology Research Laboratory, Mayo Clinic, Rochester, MN 55905, USA
    Arch Neurol 68:1290-4. 2011
    ..Diabetes mellitus (DM) is associated with an increased prevalence of peripheral arterial disease and medial arterial calcification (MAC), possibly related to prevalence and severity of diabetic polyneuropathy (DPN)...
  27. ncbi request reprint Inflammatory mediators in diabetic and non-diabetic lumbosacral radiculoplexus neuropathy
    Nobutoshi Kawamura
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Acta Neuropathol 115:231-9. 2008
    ..Up-regulated inflammatory mediators may be immunotherapeutic targets in these two conditions...
  28. ncbi request reprint Identification of transthyretin variants by sequential proteomic and genomic analysis
    H Robert Bergen
    WM Keck FT ICR Mass Spectrometry Laboratory, Mayo Proteomics Research Center, Mayo Clinic College of Medicine, Rochester, MN, USA
    Clin Chem 50:1544-52. 2004
    ....
  29. doi request reprint Post-surgical inflammatory neuropathy
    Nathan P Staff
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Brain 133:2866-80. 2010
    ....
  30. pmc Celiac disease in type 1 diabetes mellitus in a North American community: prevalence, serologic screening, and clinical features
    Farid H Mahmud
    From the Division of Pediatric Endocrinology and Metabolism, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 80:1429-34. 2005
    ....
  31. doi request reprint Antibodies to myelin-associated glycoprotein (anti-Mag) in IgM amyloidosis may influence expression of neuropathy in rare patients
    Mercedes Garces-Sanchez
    Peripheral Nerve Research Laboratory, Mayo Clinic, Rochester, MN 55905, USA
    Muscle Nerve 37:490-5. 2008
    ..They do not appear to affect the occurrence or expression of polyneuropathy, except possibly in occasional cases with WB positivity...
  32. ncbi request reprint The clinical heterogeneity of immune sensory and autonomic neuropathies with (or without) sicca
    PETER JAMES DYCK
    The Peripheral Neuropathy Research Laboratory, Mayo Clinic College of Medicine, Rochester, MN, USA
    Brain 128:2480-2. 2005

Research Grants14

  1. DIABETIC NEUROPATHY STUDY
    PETER DYCK; Fiscal Year: 2007
    ..abstract_text> ..
  2. DIABETIC NEUROPATHY STUDY
    PETER DYCK; Fiscal Year: 2003
    ....