Timothy B Curry

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. doi Relationship of muscle sympathetic nerve activity to insulin sensitivity
    Timothy B Curry
    Department of Anesthesiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA
    Clin Auton Res 24:77-85. 2014
  2. pmc Sympathetic support of energy expenditure and sympathetic nervous system activity after gastric bypass surgery
    Timothy B Curry
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA
    Obesity (Silver Spring) 21:480-5. 2013
  3. pmc Gastric bypass surgery is associated with near-normal insulin suppression of lipolysis in nondiabetic individuals
    Timothy B Curry
    Depts of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Physiol Endocrinol Metab 300:E746-51. 2011
  4. ncbi Acquired long QT syndrome and elective anesthesia in children
    Timothy B Curry
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55902, USA
    Paediatr Anaesth 16:471-8. 2006
  5. ncbi Nitrogen washout during a fatty meal while breathing nitrogen-free gas at sea level
    Timothy B Curry
    University at Buffalo, Buffalo, NY, USA
    Aviat Space Environ Med 82:725-8. 2011
  6. pmc The use of real-time ultrasound in microneurography
    Timothy B Curry
    Department of Anesthesiology and Physiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Auton Neurosci 162:89-93. 2011
  7. pmc Aging enhances autonomic support of blood pressure in women
    Jill N Barnes
    Department of Anesthesiology, Mayo Clinic, 200 1st St SW, SMH, Joseph 4 184, Rochester, MN 55905
    Hypertension 63:303-8. 2014
  8. pmc Roles of nitric oxide synthase and cyclooxygenase in leg vasodilation and oxygen consumption during prolonged low-intensity exercise in untrained humans
    William G Schrage
    Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA
    J Appl Physiol (1985) 109:768-77. 2010
  9. pmc Relationship between sympathetic nerve activity and aortic wave reflection characteristics in postmenopausal women
    Emma C Hart
    Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA
    Menopause 20:967-72. 2013
  10. pmc beta2-Adrenoceptor gene variation and systemic vasodilatation during ganglionic blockade
    Christiane Hesse
    Department of Anaesthesiology, Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Physiol 588:2669-78. 2010

Detail Information

Publications46

  1. doi Relationship of muscle sympathetic nerve activity to insulin sensitivity
    Timothy B Curry
    Department of Anesthesiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA
    Clin Auton Res 24:77-85. 2014
    ..We conducted a study to determine the relationship between sympathetic activity and insulin resistance in young, healthy humans...
  2. pmc Sympathetic support of energy expenditure and sympathetic nervous system activity after gastric bypass surgery
    Timothy B Curry
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA
    Obesity (Silver Spring) 21:480-5. 2013
    ..This study was designed to determine how gastric bypass affects the sympathetically-mediated component of resting energy expenditure (REE) and muscle sympathetic nerve activity (MSNA)...
  3. pmc Gastric bypass surgery is associated with near-normal insulin suppression of lipolysis in nondiabetic individuals
    Timothy B Curry
    Depts of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Physiol Endocrinol Metab 300:E746-51. 2011
    ..However, some differences in insulin sensitivity in GB remain compared with L. Residual insulin resistance may be related to excess total body fat or abnormal lipolysis and requires further study...
  4. ncbi Acquired long QT syndrome and elective anesthesia in children
    Timothy B Curry
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55902, USA
    Paediatr Anaesth 16:471-8. 2006
    ..Additionally, this case emphasizes the need to inquire about the use of supplements and naturopathic medications, even in children, that may have life-threatening side effects or interactions with anesthetic agents...
  5. ncbi Nitrogen washout during a fatty meal while breathing nitrogen-free gas at sea level
    Timothy B Curry
    University at Buffalo, Buffalo, NY, USA
    Aviat Space Environ Med 82:725-8. 2011
    ....
  6. pmc The use of real-time ultrasound in microneurography
    Timothy B Curry
    Department of Anesthesiology and Physiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Auton Neurosci 162:89-93. 2011
    ..In this paper, we describe the use of real-time ultrasound guidance to assist with microneurography, including advantages, disadvantages, and proper training...
  7. pmc Aging enhances autonomic support of blood pressure in women
    Jill N Barnes
    Department of Anesthesiology, Mayo Clinic, 200 1st St SW, SMH, Joseph 4 184, Rochester, MN 55905
    Hypertension 63:303-8. 2014
    ....
  8. pmc Roles of nitric oxide synthase and cyclooxygenase in leg vasodilation and oxygen consumption during prolonged low-intensity exercise in untrained humans
    William G Schrage
    Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA
    J Appl Physiol (1985) 109:768-77. 2010
    ..Furthermore, NOS and COX do not appear to influence muscle VO2 in untrained healthy young adults...
  9. pmc Relationship between sympathetic nerve activity and aortic wave reflection characteristics in postmenopausal women
    Emma C Hart
    Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA
    Menopause 20:967-72. 2013
    ..In young women, there is an inverse relationship. We investigated whether this inverse relationship persisted in postmenopausal women...
  10. pmc beta2-Adrenoceptor gene variation and systemic vasodilatation during ganglionic blockade
    Christiane Hesse
    Department of Anaesthesiology, Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Physiol 588:2669-78. 2010
    ....
  11. pmc Cardiac baroreflex sensitivity is not correlated to sympathetic baroreflex sensitivity within healthy, young humans
    Andrea P Dutoit
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    Hypertension 56:1118-23. 2010
    ..However, sex-stratified data indicate that sex-based differential correlations might exist...
  12. pmc Vasoconstrictor responsiveness during hyperbaric hyperoxia in contracting human muscle
    Darren P Casey
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Appl Physiol (1985) 114:217-24. 2013
    ....
  13. pmc Sex and ageing differences in resting arterial pressure regulation: the role of the β-adrenergic receptors
    Emma C Hart
    Department of Anaesthesiology, Mayo Clinic, Rochester, MN, USA
    J Physiol 589:5285-97. 2011
    ..Our data suggest that the β-adrenergic receptors offset α-adrenergic vasoconstriction in young women but not young men or PM women. These findings may explain in part the tendency for blood pressure to rise after menopause in women...
  14. pmc Acute β-adrenergic blockade increases aortic wave reflection in young men and women: differing mechanisms between sexes
    Darren P Casey
    Department of Anesthesiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Hypertension 59:145-50. 2012
    ....
  15. pmc Do the carotid bodies modulate hypoglycemic counterregulation and baroreflex control of blood pressure in humans?
    Erica A Wehrwein
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55904, USA
    Adv Exp Med Biol 758:129-35. 2012
    ..These data support the idea that the carotid bodies play a role in the counterregulatory response to hypoglycemia and in baroreflex control of blood pressure in humans...
  16. pmc Sex differences in sympathetic neural-hemodynamic balance: implications for human blood pressure regulation
    Emma C Hart
    Department of Anesthesiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Hypertension 53:571-6. 2009
    ..These findings may have important implications for understanding how hypertension and other disorders of blood pressure regulation occur in men and women...
  17. pmc Age-related differences in the sympathetic-hemodynamic balance in men
    Emma C Hart
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    Hypertension 54:127-33. 2009
    ....
  18. pmc The effects of acute beta-adrenergic blockade on aortic wave reflection in postmenopausal women
    Darren P Casey
    Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA
    Am J Hypertens 26:503-10. 2013
    ..Taken together, our data suggest that the negative effects (i.e. increased aortic wave reflection) of nonselective beta-adrenergic blockade are less pronounced in postmenopausal than in young women...
  19. pmc Hysteresis in the sympathetic baroreflex: role of baseline nerve activity
    Emma C Hart
    Department of Anesthesiology, Mayo Clinic, 200 First St SW, Rochester, MN 59906, USA
    J Physiol 589:3395-404. 2011
    ..Furthermore, the lack of relationship in young women suggests important contributions of sex hormones to differential responses of MSNA to falling and rising pressures...
  20. pmc Hyperbaric hyperoxia reduces exercising forearm blood flow in humans
    Darren P Casey
    Dept of Anesthesiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905
    Am J Physiol Heart Circ Physiol 300:H1892-7. 2011
    ..01). Our data suggest that exercise hyperemia in skeletal muscle is highly dependent on oxygen availability during hyperoxia...
  21. pmc Relationship between muscle sympathetic nerve activity and aortic wave reflection characteristics in young men and women
    Darren P Casey
    Department of Anesthesiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Hypertension 57:421-7. 2011
    ..59), and wasted left ventricular energy (r = -0.58; P<0.01 for all). Our results suggest another possible mechanism by which young women are protected against the development of cardiovascular disease...
  22. pmc Nitric oxide contributes to the augmented vasodilatation during hypoxic exercise
    Darren P Casey
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    J Physiol 588:373-85. 2010
    ..7 vs. -21.4 +/- 5.2%; P = 0.28) and 20% (-13.4 +/- 3.5 vs. -18.8 +/- 4.5%; P = 0.18) hypoxic exercise. These findings suggest that NO contributes to the augmented vasodilatation observed during hypoxic exercise independent of adenosine...
  23. pmc Effects of respiratory muscle work on blood flow distribution during exercise in heart failure
    Thomas P Olson
    Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA
    J Physiol 588:2487-501. 2010
    ..Further, HF patients are unable to vasoconstrict locomotor vascular beds beyond NB when presented with a respiratory load...
  24. pmc Baroreflex control of muscle sympathetic nerve activity: a nonpharmacological measure of baroreflex sensitivity
    Emma C Hart
    Dept of Anesthesiology, Mayo Clinic, Rochester, MN 59906, USA
    Am J Physiol Heart Circ Physiol 298:H816-22. 2010
    ..Furthermore, the modified Oxford method does not appear to alter the properties of the baroreflex...
  25. pmc Ageing reduces the compensatory vasodilatation during hypoxic exercise: the role of nitric oxide
    Darren P Casey
    Department of Anesthesiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    J Physiol 589:1477-88. 2011
    ..L-NMMA during hypoxic exercise only blunted the compensatory vasodilator response in the young group (P <0.05). Our data suggest that ageing reduces the compensatory vasodilator response to hypoxic exercise via blunted NO signalling...
  26. pmc Nitric oxide-mediated vasodilation becomes independent of beta-adrenergic receptor activation with increased intensity of hypoxic exercise
    Darren P Casey
    Dept of Anesthesiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    J Appl Physiol (1985) 110:687-94. 2011
    ..However, the source of the NO becomes less dependent on β-adrenergic mechanisms as exercise intensity increases...
  27. doi Influence of locomotor muscle afferent inhibition on the ventilatory response to exercise in heart failure
    Thomas P Olson
    Mayo Clinic, Division of Cardiovascular Diseases, 200 First Street SW, Rochester, MN 55905, USA
    Exp Physiol 99:414-26. 2014
    ..These data suggest that inhibition of afferent feedback from locomotor muscle significantly reduces the ventilatory response to exercise in HF patients...
  28. pmc Association of cardiac baroreflex sensitivity with blood pressure transients: influence of sex and menopausal status
    Jill N Barnes
    Human Integrative Physiology Laboratory, Department of Anesthesiology, Mayo Clinic, Rochester MN, USA
    Front Physiol 3:187. 2012
    ..The fact that these relationships do not exist in young women suggest that the female sex hormones influence baroreflex responses...
  29. pmc Preoperative gabapentin for acute post-thoracotomy analgesia: a randomized, double-blinded, active placebo-controlled study
    Michelle A O Kinney
    Department of Anesthesiology, College of Medicine Mayo Clinic, Rochester, Minnesota, USA
    Pain Pract 12:175-83. 2012
    ..Patients undergoing thoracotomy benefit from epidural analgesia but still may experience significant postoperative pain. We examined the effect of preoperative gabapentin in thoracotomy patients...
  30. doi Complications following 573 percutaneous renal radiofrequency and cryoablation procedures
    Thomas D Atwell
    Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55902, USA
    J Vasc Interv Radiol 23:48-54. 2012
    ..To review complications related to percutaneous renal tumor ablation...
  31. doi What we talk about when we talk with medical students
    Michael J Joyner
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Adv Physiol Educ 35:16-21. 2011
    ..In this article, we discuss the philosophy behind the themes outlined above and argue that questions, and not answers, are where the action is for both research and education...
  32. doi Acute effects of a mixed meal on arterial stiffness and central hemodynamics in healthy adults
    Jennifer L Taylor
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota
    Am J Hypertens 27:331-7. 2014
    ..However, the acute effects of a meal on aortic wave reflection and stiffness are unknown. Therefore, we tested the hypothesis that aortic wave reflection and stiffness would increase after a meal...
  33. doi Changes in red blood cell transfusion practice during the turn of the millennium: a retrospective analysis of adult patients undergoing elective open abdominal aortic aneurysm repair using the Mayo database
    Timothy R Long
    Department of Anesthesiology, College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Ann Vasc Surg 24:447-54. 2010
    ..Significant changes in perioperative red blood cell (RBC) transfusion practice during the past two decades have been reported but similar data are not available for patients undergoing abdominal aortic aneurysm (AAA) surgery...
  34. pmc Postural orthostatic tachycardia syndrome and general anesthesia: a series of 13 cases
    Jennifer A Rabbitts
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    J Clin Anesth 23:384-92. 2011
    ..To investigate whether patients with postural orthostatic tachycardia syndrome (POTS) developed unexpected perioperative complications...
  35. pmc Hyperoxia blunts counterregulation during hypoglycaemia in humans: possible role for the carotid bodies?
    Erica A Wehrwein
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    J Physiol 588:4593-601. 2010
    ..1%, growth hormone 53.1 ± 2.7%, glucagon 48.6 ± 2.1%, all P < 0.05 vs. normoxia). These data support the idea that the carotid bodies respond to glucose and play a role in the counterregulatory response to hypoglycaemia in humans...
  36. pmc Adenosine transporter antagonism in humans augments vasodilator responsiveness to adenosine, but not exercise, in both adenosine responders and non-responders
    Elizabeth A Martin
    Department of Anesthesiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Physiol 579:237-45. 2007
    ..The failure of DIP to augment exercise hyperemia under these conditions suggests that ADO concentrations may not rise enough during rhythmic handgripping to have a major impact on these responses...
  37. doi Pharmacogenetic workup of perioperative serotonin syndrome
    Nicole C Beatty
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA Electronic address
    J Clin Anesth 25:662-5. 2013
    ..For this patient, who was taking combination antidepressant medications and receiving common perioperative medicines, additive pharmacodynamic effects converged with a pharmacogenetic predisposition, resulting in serotonin syndrome. ..
  38. ncbi Excessive heart rate response to orthostatic stress in postural tachycardia syndrome is not caused by anxiety
    Shizue Masuki
    Dept of Anesthesiology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    J Appl Physiol 102:896-903. 2007
    ..1). These results suggest that the HR response to orthostatic stress in POTS patients is not caused by anxiety but that it is a physiological response that maintains arterial pressure during venous pooling...
  39. doi Palliation of painful metastatic disease involving bone with imaging-guided treatment: comparison of patients' immediate response to radiofrequency ablation and cryoablation
    Paul G Thacker
    Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    AJR Am J Roentgenol 197:510-5. 2011
    ....
  40. ncbi Negative pressure breathing enhances nitrogen elimination
    Timothy B Curry
    Center for Research and Education in Special Environments, Department of Physiology and Biophysics, University at Buffalo, Buffalo, NY 14222, USA
    Aviat Space Environ Med 74:1034-9. 2003
    ..Negative pressure breathing (NPB) is thought to increase CO by enhancing venous return and, consequently, the rate of nitrogen elimination. This notion was investigated in the present study...
  41. doi Sacral tumor resection: the effect of surgical staging on patient outcomes, resource management, and hospital cost
    Michael J Brown
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    Spine (Phila Pa 1976) 36:1570-8. 2011
    ..Single-institution retrospective study...
  42. pmc Measuring muscle blood flow: a key link between systemic and regional metabolism
    Darren P Casey
    Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Curr Opin Clin Nutr Metab Care 11:580-6. 2008
    ..To provide a brief overview of the main techniques to measure muscle blood flow in humans and highlight some of the strengths and weaknesses associated with each technique...
  43. ncbi Airway management after failure to intubate by direct laryngoscopy: outcomes in a large teaching hospital
    Christopher M Burkle
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Can J Anaesth 52:634-40. 2005
    ....
  44. ncbi Lung isolation, one-lung ventilation, and continuous positive airway pressure with air for radiofrequency ablation of neoplastic pulmonary lesions
    Beth A Elliott
    Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Anesth Analg 103:463-4, table of contents. 2006
    ..Lung isolation, one-lung ventilation, and nondependent lung continuous positive airway pressure with air can be used to minimize damage to the heart and other important structures...
  45. ncbi The history of subcutaneous oxygen therapy
    Timothy B Curry
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    J Clin Anesth 18:388-95. 2006
    ..Although SQOT has been supplanted by other means of administration, it may have a role in management of some inflammatory or pain conditions...
  46. pmc Exercise intensity-dependent contribution of beta-adrenergic receptor-mediated vasodilatation in hypoxic humans
    Brad W Wilkins
    Department of Human Physiology, 122 Esslinger Hall, 1240 University of Oregon, Eugene, OR 97403 1240, USA
    J Physiol 586:1195-205. 2008
    ..Thus, in the absence of overlying vasoconstriction, the contribution of beta-adrenergic mechanisms to the augmented hypoxic vasodilatation is dependent on exercise intensity...