Research Topics
| Bart ClarkeSummaryAffiliation: Mayo Clinic Country: USA Publications
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Detail Information
Publications
New and emerging treatments for osteoporosisBart L Clarke
Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN 55905, USA
Clin Endocrinol (Oxf) 71:309-21. 2009..The increasing variety of new and emerging treatments increases the possibility that effective therapy will be targeted to the specific needs of the individual patient...- Epidemiology of primary hyperparathyroidismBart L Clarke
College of Medicine, Mayo Clinic, Rochester, MN, USA
J Clin Densitom 16:8-13. 2013..These limitations are due to the small number of population-based epidemiologic studies that have evaluated this condition. Further studies will be required to fully characterize the epidemiology of primary hyperparathyroidism... - Corticosteroid-induced osteoporosis: an update for dermatologistsBart L Clarke
Mayo Clinic School of Medicine, Rochester, MN, USA
Am J Clin Dermatol 13:167-90. 2012..This article gives an update of current knowledge regarding the pathophysiology, clinical presentation and evaluation, and prevention and treatment of patients with corticosteroid-induced osteoporosis... 
Female reproductive system and boneBart L Clarke
College of Medicine, Mayo Clinic, Rochester, MN, USA
Arch Biochem Biophys 503:118-28. 2010....- Physiology of bone lossBart L Clarke
Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic College of Medicine, 200 1st Street Southwest, Rochester, MN 55905, USA
Radiol Clin North Am 48:483-95. 2010..Further elucidation of the relative importance of each of these factors will lead to improved preventive and therapeutic approaches for osteoporosis... - Androgens and boneBart L Clarke
Mayo Clinic W18 A, 200 1st Street SW, Rochester, MN 55905, USA
Steroids 74:296-305. 2009..Whether high doses of synthetic, non-aromatizable androgens may, in fact, be detrimental to bone due to suppression of endogenous testosterone (and estrogen) levels is a potential concern that warrants further study... - Normal bone anatomy and physiologyBart Clarke
Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, W18 A, 200 1st Street SW, Rochester, MN 55905, USA
Clin J Am Soc Nephrol 3:S131-9. 2008..This information lays the groundwork for understanding the utility and clinical applications of iliac crest bone biopsy... 
Oral bisphosphonate therapy and osteonecrosis of the jaw: what to tell the concerned patientSreenivas Koka
Metabolic Bone Disease Core Group, Division of Prosthodontics, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Int J Prosthodont 20:115-22. 2007..Within this context, management concepts and guidelines are presented to help the dental clinician allay concerns about BONJ expressed by patients receiving oral bisphosphonate therapy...- Bisphosphonates: mechanism of action and role in clinical practiceMatthew T Drake
Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN 55905, USA
Mayo Clin Proc 83:1032-45. 2008.... - Diagnosis, screening, prevention, and treatment of osteoporosisKaren F Mauck
Division of General Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Mayo Clin Proc 81:662-72. 2006..This article provides an overview of the diagnosis, screening, prevention, and treatment of osteoporosis... - Vitamin D insufficiencyTom D Thacher
Department of Family Medicine, Mayo Clinic, Rochester, MN 55905, USA
Mayo Clin Proc 86:50-60. 2011..Conclusive demonstration of these benefits awaits the outcome of controlled clinical trials... - Germline TGF-beta receptor mutations and skeletal fragility: a report on two patients with Loeys-Dietz syndromeSalman Kirmani
Department of Medical Genetics, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Med Genet A 152:1016-9. 2010..Osteopenia or osteoporosis may become increasingly important issues as earlier detection and treatment of the vascular complications of LDS improves life expectancy in these patients... - Bisphosphonates are not associated with vertebral osteonecrosisDavid F Kallmes
Department of Radiology, Mayo Clinic, Rochester, MN, 55905, USA
J Bone Miner Metab 27:452-5. 2009..80). Intravertebral clefts are not associated with bisphosphonate therapy. If these clefts indicate osteonecrosis, then bisphosphonate therapy does not appear to be associated with vertebral osteonecrosis... - Bone histomorphometric changes after liver transplantation for chronic cholestatic liver diseaseMaureen M J Guichelaar
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
J Bone Miner Res 18:2190-9. 2003..Therefore, despite post-transplant bone loss, by 4 months after OLT, bone metabolism had improved, with increased bone formation and more coupled bone balance, as suggested by hierarchical cluster analysis... - New selective estrogen and androgen receptor modulatorsBart L Clarke
Mayo Clinic W18 A, Rochester, Minnesota 55905, USA
Curr Opin Rheumatol 21:374-9. 2009..Both types of compounds hold great promise for therapeutic use in multiple hormonal disorders involving tissue-specific effects mediated by estrogen or androgen receptors... - Bone metabolism in advanced cholestatic liver disease: analysis by bone histomorphometryMaureen M J Guichelaar
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA
Hepatology 36:895-903. 2002.... - Immunosuppressive and postoperative effects of orthotopic liver transplantation on bone metabolismMaureen M J Guichelaar
Division of Liver Transplantation, Mayo Clinic, Rochester, MN 55905, USA
Liver Transpl 10:638-47. 2004..Other factors important in the recovery of bone metabolism after the early phase of bone loss are recovery of liver and gonadal function and better calcium balance... - Glucocorticoid-induced osteoporosis in dermatologic practice: a reviewYulia K Khan
Mayo Medical School, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
J Drugs Dermatol 7:1053-9. 2008..This summary should aid dermatologists in providing education and recommendations regarding bone health for their patients on systemic glucocorticoids... - Site specificity of regular health club exercise on muscle strength, fitness, and bone density in women aged 29 to 45 yearsMehrsheed Sinaki
Department of Physical Medicine and Rehabilitation, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 79:639-44. 2004..01; left, P=.049). CONCLUSION: Although comparable health club exercises can contribute to fitness, their site-specific effect varies. Stepper machines are preferred over skier machines for improving hip extensor strength... - Fibroblast growth factor 23, parathyroid hormone, and 1alpha,25-dihydroxyvitamin D in surgically treated primary hyperparathyroidismPeter J Tebben
Division of Endocrinology, Diabetes, Metabolism, and Nutrition and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 79:1508-13. 2004..Fibroblast growth factor 23 does not appear to play a role in phosphorus homeostasis in patients with surgically treated primary hyperparathyroidism... - Long-term fracture risk following renal transplantation: a population-based studyLine M Vautour
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, Minn, USA
Osteoporos Int 15:160-7. 2004..Diabetic patients, particularly, experience excess lower limb fractures. Patients and their care providers should be aware of this elevated fracture risk, which continues long-term...