J C Cheville

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. doi request reprint Chromophobe renal cell carcinoma: the impact of tumor grade on outcome
    John C Cheville
    Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Surg Pathol 36:851-6. 2012
  2. pmc Optimization of laser capture microdissection and RNA amplification for gene expression profiling of prostate cancer
    Dagmar M Kube
    Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    BMC Mol Biol 8:25. 2007
  3. ncbi request reprint Sarcomatoid renal cell carcinoma: an examination of underlying histologic subtype and an analysis of associations with patient outcome
    John C Cheville
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 28:435-41. 2004
  4. ncbi request reprint pT1 clear cell renal cell carcinoma: a study of the association between MIB-1 proliferative activity and pathologic features and cancer specific survival
    John C Cheville
    Department of Pathology and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 94:2180-4. 2002
  5. ncbi request reprint MAGE-1 and MAGE-3 tumor rejection antigens in human germ cell tumors
    J C Cheville
    Department of Pathology and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Mod Pathol 12:974-8. 1999
  6. ncbi request reprint Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma
    John C Cheville
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Surg Pathol 27:612-24. 2003
  7. ncbi request reprint Classification and pathology of testicular germ cell and sex cord-stromal tumors
    J C Cheville
    Department of Pathology, Mayo Clinic, Rochester, Minnesota, USA
    Urol Clin North Am 26:595-609. 1999
  8. ncbi request reprint Metastatic prostate carcinoma to bone: clinical and pathologic features associated with cancer-specific survival
    John C Cheville
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 95:1028-36. 2002
  9. ncbi request reprint Extranodal extension in lymph node-positive prostate cancer
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Mod Pathol 13:113-8. 2000
  10. ncbi request reprint Predicting prostate carcinoma volume and stage at radical prostatectomy by assessing needle biopsy specimens for percent surface area and cores positive for carcinoma, perineural invasion, Gleason score, DNA ploidy and proliferation, and preoperative seru
    T J Sebo
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 91:2196-204. 2001

Detail Information

Publications92

  1. doi request reprint Chromophobe renal cell carcinoma: the impact of tumor grade on outcome
    John C Cheville
    Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Surg Pathol 36:851-6. 2012
    ....
  2. pmc Optimization of laser capture microdissection and RNA amplification for gene expression profiling of prostate cancer
    Dagmar M Kube
    Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    BMC Mol Biol 8:25. 2007
    ..Here we present methods developed, optimized, and validated to obtain high quality gene expression data...
  3. ncbi request reprint Sarcomatoid renal cell carcinoma: an examination of underlying histologic subtype and an analysis of associations with patient outcome
    John C Cheville
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 28:435-41. 2004
    ..59; P = 0.010) and after adjusting for TNM stage, tumor size, and histologic tumor necrosis (risk ratio 1.46; P = 0.037)...
  4. ncbi request reprint pT1 clear cell renal cell carcinoma: a study of the association between MIB-1 proliferative activity and pathologic features and cancer specific survival
    John C Cheville
    Department of Pathology and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 94:2180-4. 2002
    ....
  5. ncbi request reprint MAGE-1 and MAGE-3 tumor rejection antigens in human germ cell tumors
    J C Cheville
    Department of Pathology and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Mod Pathol 12:974-8. 1999
    ..The significance of MAGE-1 and MAGE-3 proteins in normal spermatogonia and primary spermatocytes will require additional study...
  6. ncbi request reprint Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma
    John C Cheville
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Surg Pathol 27:612-24. 2003
    ..Our results demonstrate that there are significant differences in outcome and associations with outcome for the different histologic subtypes of RCC, highlighting the need for accurate subtyping...
  7. ncbi request reprint Classification and pathology of testicular germ cell and sex cord-stromal tumors
    J C Cheville
    Department of Pathology, Mayo Clinic, Rochester, Minnesota, USA
    Urol Clin North Am 26:595-609. 1999
    ..The urologist can provide the pathologist with key clinical information in the attempt to make a correct diagnosis...
  8. ncbi request reprint Metastatic prostate carcinoma to bone: clinical and pathologic features associated with cancer-specific survival
    John C Cheville
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 95:1028-36. 2002
    ..The objective of this study was to examine the clinical and pathologic features of metastatic prostate carcinoma to bone in a large cohort of men, and the associations of these features with outcome...
  9. ncbi request reprint Extranodal extension in lymph node-positive prostate cancer
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Mod Pathol 13:113-8. 2000
    ..In contrast, nodal cancer volume was predictive of distant metastasis-free survival and cancer-specific survival...
  10. ncbi request reprint Predicting prostate carcinoma volume and stage at radical prostatectomy by assessing needle biopsy specimens for percent surface area and cores positive for carcinoma, perineural invasion, Gleason score, DNA ploidy and proliferation, and preoperative seru
    T J Sebo
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 91:2196-204. 2001
    ....
  11. ncbi request reprint Long-term survival of patients with unilateral sporadic multifocal renal cell carcinoma according to histologic subtype compared with patients with solitary tumors after radical nephrectomy
    David S Dimarco
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55901, USA
    Urology 64:462-7. 2004
    ..To determine the pathologic features, including histologic subtype and tumor size, associated with multifocal renal cell carcinoma (RCC) and the impact of multifocality on survival after radical nephrectomy, about which controversy exists...
  12. ncbi request reprint Paraganglioma of the urinary bladder: can biologic potential be predicted?
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Cancer 88:844-52. 2000
    ..Paraganglioma of the urinary bladder is rarely encountered and its biologic behavior is uncertain. The authors sought to determine the prognostic factors that would predict patient outcome...
  13. ncbi request reprint The cell cycle inhibitors p21WAF1 and p27KIP1 are associated with survival in patients treated by salvage prostatectomy after radiation therapy
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Clin Cancer Res 6:1896-9. 2000
    ..06 and 0.01, respectively). These findings indicate that p21 and p27 expression levels are significant predictors of survival for patients selected for salvage prostatectomy for recurrent prostate cancer...
  14. ncbi request reprint Stage pT1 conventional (clear cell) renal cell carcinmoa: pathological features associated with cancer specific survival
    J C Cheville
    Departments of Pathology and Laboratory Medicine, Urology and Biostatistics, Mayo Clinic, Rochester, Minnesota, USA
    J Urol 166:453-6. 2001
    ..Specifically of the tumor size cutoffs analyzed the 5 cm. cutoff was most predictive of cancer specific survival...
  15. ncbi request reprint Diagnosis of prostate cancer in needle biopsies after radiation therapy
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Am J Surg Pathol 23:1173-83. 1999
    ..Conversely, Gleason grade in postirradiation needle biopsy specimens appeared to provide useful predictive information and should be reported...
  16. ncbi request reprint The effect of bilaterality, pathological features and surgical outcome in nonhereditary renal cell carcinoma
    Michael L Blute
    Department of Urology, Mayo Clinic, Rochester, Minnesota, USA
    J Urol 169:1276-81. 2003
    ..We also analyzed early surgical complications and long-term renal function in patients who underwent staged surgery and those who underwent a single operation for bilateral synchronous renal cell carcinoma...
  17. doi request reprint Outcomes following partial nephrectomy by tumor size
    Paul L Crispen
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 180:1912-7. 2008
    ..We established long-term survival in patients following partial nephrectomy according to tumor size...
  18. ncbi request reprint Nephron-sparing surgery for renal cell carcinoma: clinicopathologic features predictive of patient outcome
    Kent G Krejci
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Urology 62:641-6. 2003
    ..To determine the clinicopathologic features associated with outcome in patients with sporadic renal cell carcinoma (RCC) treated with nephron-sparing surgery...
  19. ncbi request reprint Serous borderline tumor of the paratestis: a report of seven cases
    R F McClure
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Surg Pathol 25:373-8. 2001
    ..To date, no serous borderline tumor of the paratestis reported in the literature or in our series has recurred or metastasized after resection...
  20. ncbi request reprint Atypical nephrogenic metaplasia of the urinary tract: a precursor lesion?
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Cancer 88:853-61. 2000
    ..Nephrogenic metaplasia with cytologic atypia (atypical nephrogenic metaplasia) is occasionally encountered and its biologic potential is uncertain...
  21. ncbi request reprint Squamous papilloma of the urinary tract is unrelated to condyloma acuminata
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Cancer 88:1679-86. 2000
    ..To the authors' knowledge, there is no previous report of squamous papilloma of the urinary tract. It is uncertain whether there is a correlation between squamous papilloma, condyloma acuminatum, and verrucous carcinoma...
  22. ncbi request reprint Ki-67 and coagulative tumor necrosis are independent predictors of poor outcome for patients with clear cell renal cell carcinoma and not surrogates for each other
    Matthew K Tollefson
    Department of Urology, Mayo Clinic and Mayo Medical School, Rochester, MN 55905, USA
    Cancer 110:783-90. 2007
    ..Thus, the goal was to directly test whether Ki-67 and necrosis convey similar or distinct information for the prognostic assessment of ccRCC...
  23. ncbi request reprint Charlson co-morbidity index as a predictor of outcome after surgery for renal cell carcinoma with renal vein, vena cava or right atrium extension
    Matthew T Gettman
    Department of Urology, Division of Anatomic Pathology and Section of Biostatistics, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 169:1282-6. 2003
    ..We analyzed the Charlson co-morbidity index as a predictor of outcome after surgery...
  24. ncbi request reprint An outcome prediction model for patients with clear cell renal cell carcinoma treated with radical nephrectomy based on tumor stage, size, grade and necrosis: the SSIGN score
    Igor Frank
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota, USA
    J Urol 168:2395-400. 2002
    ....
  25. ncbi request reprint Urothelial papilloma of the bladder. Clinical and biologic implications
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Cancer 86:2098-101. 1999
    ..An international consensus has been reached regarding diagnostic criteria for papilloma of the urinary bladder. However, the incidences of recurrence and progression in patients with urothelial papilloma are uncertain...
  26. ncbi request reprint A multifactorial postoperative surveillance model for patients with surgically treated clear cell renal cell carcinoma
    Igor Frank
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota, USA
    J Urol 170:2225-32. 2003
    ..We designed scoring algorithms for postoperative surveillance based on multivariately significant predictors of site specific disease recurrence...
  27. ncbi request reprint Renal cell carcinoma in the solitary kidney: an analysis of complications and outcome after nephron sparing surgery
    Reza Ghavamian
    Department of Laboratory Medicine, Health Sciences Research and Urology, Mayo Clinic, Rochester, Minnesota, USA
    J Urol 168:454-9. 2002
    ..We evaluated surgical techniques, pathological features and extended outcomes in patients with renal cell carcinoma in a solitary kidney treated with surgical excision...
  28. ncbi request reprint Histologic coagulative tumor necrosis as a prognostic indicator of renal cell carcinoma aggressiveness
    Shomik Sengupta
    Department of Urology, Mayo Medical School and Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Cancer 104:511-20. 2005
    ..90; P < 0.001). CONCLUSIONS: Histologic coagulative tumor necrosis is an independent predictor of outcome for clear cell and chromophobe RCC, and it should be routinely reported and used in clinical assessment...
  29. ncbi request reprint Clear cell renal cell carcinoma: gene expression analyses identify a potential signature for tumor aggressiveness
    Farhad Kosari
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Clin Cancer Res 11:5128-39. 2005
    ..The objective of this study was to use gene expression profiling to identify novel biomarkers that are predictive of aggressive behavior in clear cell renal cell carcinoma (CCRCC)...
  30. ncbi request reprint Reclassification of patients with pT3 and pT4 renal cell carcinoma improves prognostic accuracy
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 104:53-60. 2005
    ....
  31. ncbi request reprint Prognostic features of pathologic stage T1 renal cell carcinoma after radical nephrectomy
    Weber K Lau
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Urology 59:532-7. 2002
    ..CONCLUSIONS: RCC subtype is a strong independent prognostic variable for patients with pT1 RCC treated with radical nephrectomy. For clear cell RCC, Fuhrman grade and tumor size are independently associated with CSS and MFS...
  32. pmc p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers
    R V Lloyd
    Department of Laboratory Medicine and Pathology, Mayo Foundation and Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Pathol 154:313-23. 1999
    ..We also review studies indicating the increasingly important roles of p27, other CDKIs, and cyclins in endocrine cell hyperplasia and tumor development...
  33. ncbi request reprint The influence of pNx/pN0 grouping in a multivariate setting for outcome modeling in patients with clear cell renal cell carcinoma
    John F Ward
    Department of Urology, and Section of Biostatistics, Mayo Clinic, Rochester, Minnesota, USA
    J Urol 168:56-60. 2002
    ..We evaluated cancer specific survival differences in patients with clear cell renal cell carcinoma and a lymph node stage of pNx, pN0 or pN1/pN2...
  34. doi request reprint Identification of prognostic biomarkers for prostate cancer
    Farhad Kosari
    Mayo Clinic Cancer Center, Department of Laboratory Medicine and Pathology, Rochester, Minnesota 55905, USA
    Clin Cancer Res 14:1734-43. 2008
    ..This paper describes a process for the identification of genes that can report on the aggressiveness of prostate tumors and thereby add to the information provided by current pathologic analysis...
  35. ncbi request reprint Patients with pT1 renal cell carcinoma who die from disease after nephrectomy may have unrecognized renal sinus fat invasion
    Robert Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 31:1089-93. 2007
    ..Appropriate assessment of nephrectomy specimens should include proper sampling of the renal sinus even for seemingly localized tumors...
  36. ncbi request reprint Carbonic anhydrase IX is not an independent predictor of outcome for patients with clear cell renal cell carcinoma
    Bradley C Leibovich
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 25:4757-64. 2007
    ..We attempted to validate the prognostic utility of CAIX expression using a large cohort of ccRCC patients with long-term follow-up...
  37. ncbi request reprint Metanephric adenoma, nephrogenic rests, and Wilms' tumor: a histologic and immunophenotypic comparison
    T E Muir
    Department of Laboratory Medicine and Pathology, Mayo Foundation, Rochester, Minnesota 55905, USA
    Am J Surg Pathol 25:1290-6. 2001
    ..Metanephric adenoma is histogenetically related to WT and is morphologically and immunophenotypically identical to maturing WT and nephrogenic rests...
  38. ncbi request reprint Natural history of urothelial dysplasia of the bladder
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Am J Surg Pathol 23:443-7. 1999
    ..The authors conclude that urothelial dysplasia is a significant risk for the development of CIS and invasive urothelial carcinoma, and patients with urothelial dysplasia should be followed up closely...
  39. ncbi request reprint Permanent prostate brachytherapy: pathologic implications as assessed on radical prostatectomy specimens of broadening selection criteria for monotherapy
    Shomik Sengupta
    Department of Urology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Urology 68:810-4. 2006
    ....
  40. ncbi request reprint A review of prognostic pathologic features and algorithms for patients treated surgically for renal cell carcinoma
    Christine M Lohse
    Division of Biostatistics, Mayo Clinic, Rochester, MN 55905, USA
    Clin Lab Med 25:433-64. 2005
    ..The features that are reported routinely in clinical practice also are indicated; this can serve as a guide for the reporting of results from the pathologic examination of RCC...
  41. ncbi request reprint High expression levels of insulin-like growth factor-I receptor predict poor survival among women with clear-cell renal cell carcinomas
    Alexander S Parker
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Hum Pathol 33:801-5. 2002
    ....
  42. pmc Hypermethylation of genes for diagnosis and risk stratification of prostate cancer
    Donkena Krishna Vanaja
    Department of Urology, Mayo Clinic Foundation, Rochester, Minnesota 55905, USA
    Cancer Invest 27:549-60. 2009
    ..Furthermore, CpG site hypermethylation of genes FLNC, EFS, ECRG4, PITX2, PDLIM4, and KCNMA1 were associated with prediction of biochemical, local, and systemic recurrence of prostate cancer...
  43. ncbi request reprint Transcriptional silencing of zinc finger protein 185 identified by expression profiling is associated with prostate cancer progression
    Donkena Krishna Vanaja
    Department of Urology, Mayo Clinic Foundation, Rochester, Minnesota 55905, USA
    Cancer Res 63:3877-82. 2003
    ..Thus, transcriptional silencing of ZNF185 by methylation in prostate tumor tissues implicates the ZNF185 gene in prostate tumorigenesis...
  44. pmc Gene panel model predictive of outcome in men at high-risk of systemic progression and death from prostate cancer after radical retropubic prostatectomy
    John C Cheville
    Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    J Clin Oncol 26:3930-6. 2008
    ..The objective of this study was to develop a model predictive of outcome in this group of patients...
  45. ncbi request reprint PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer
    Donkena Krishna Vanaja
    Department of Urology, Mayo Clinic Foundation, Rochester, Minnesota 55905, USA
    Clin Cancer Res 12:1128-36. 2006
    ..We analyzed the expression of genes to identify reliable molecular markers in the diagnosis and progression of prostate cancer...
  46. ncbi request reprint Trends in distribution and prognostic significance of Gleason grades on radical retropubic prostatectomy specimens between 1989 and 2001
    Shomik Sengupta
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 106:2630-5. 2006
    ..The objectives of the current study were to examine time trends in the prevalence of Gleason grades of prostate cancer on radical retropubic prostatectomy (RRP) specimens and to assess the resultant impact on prognosis...
  47. ncbi request reprint Mononuclear cell infiltration in clear-cell renal cell carcinoma independently predicts patient survival
    W Scott Webster
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 107:46-53. 2006
    ..The objective of the current study was to evaluate associations between mononuclear cell infiltration in routinely prepared paraffin-embedded specimens with survival in patients with clear-cell RCC...
  48. ncbi request reprint Conventional assessment of needle biopsy specimens is more useful than digital image analysis of proliferation and DNA ploidy in prediction of positive surgical margins at radical prostatectomy
    Shomik Sengupta
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Urology 68:94-8. 2006
    ..The aim of this study was to assess the additional value of digital image analysis (DIA) of ploidy and proliferation on needle biopsies, in addition to the known preoperative predictors of +SMs at RRP...
  49. ncbi request reprint A scoring algorithm to predict survival for patients with metastatic clear cell renal cell carcinoma: a stratification tool for prospective clinical trials
    Bradley C Leibovich
    Department of Urology, Mayo Medical School, Rochester, Minnesota, USA
    J Urol 174:1759-63; discussion 1763. 2005
    ..We developed a clinically useful scoring algorithm to predict cancer specific survival for patients with clear cell metastatic renal cell carcinoma (RCC)...
  50. ncbi request reprint Lower expression levels of the transforming growth factor beta receptor type II protein are associated with a less aggressive tumor phenotype and improved survival among patients with clear cell renal cell carcinoma
    Alexander Scott Parker
    Department of Urology, Mayo Clinic, Jacksonville, FL 32224, USA
    Hum Pathol 38:453-61. 2007
    ..Data from this investigation are the first to suggest that loss of TbetaRII expression is associated with improved ccRCC patient survival, especially among those patients with less aggressive disease profiles at time of surgery...
  51. ncbi request reprint Survivin and b7-h1 are collaborative predictors of survival and represent potential therapeutic targets for patients with renal cell carcinoma
    Amy E Krambeck
    Department of Urology, Mayo Medical School, Mayo Clinic, Rochester, MN 55905, USA
    Clin Cancer Res 13:1749-56. 2007
    ..Herein, we examine the clinical effect of ccRCC combined expression of both survivin and B7-H1...
  52. pmc A p120 catenin isoform switch affects Rho activity, induces tumor cell invasion, and predicts metastatic disease
    Masahiro Yanagisawa
    Department of Cancer Biology, Mayo Clinic, Jacksonville, FL 32224, USA
    J Biol Chem 283:18344-54. 2008
    ..The data indicate that the increased expression of p120 isoform 1 during tumor progression contributes to the invasive phenotype of cadherin-deficient carcinomas and that the N-terminal domain of p120 is a valid therapeutic target...
  53. doi request reprint Postoperative surveillance for renal cell carcinoma: a multifactorial histological subtype specific protocol
    Sameer A Siddiqui
    Department of Urology, Mayo Clinic, Rochester, MN, USA
    BJU Int 104:778-85. 2009
    ....
  54. ncbi request reprint Renal carcinoid tumor: a clinicopathologic study of 21 cases
    Donna E Hansel
    Department of Pathology and Laboratory Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Am J Surg Pathol 31:1539-44. 2007
    ..Of the remaining patients, 7 patients were alive without disease and 6 patients were alive with disease. Additional metastases developed in 4 patients and included metastases to the liver and bone...
  55. ncbi request reprint Prediction of radial distance of extraprostatic extension from pretherapy factors
    David J Schwartz
    Department of Radiation Oncology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 69:411-8. 2007
    ..In this study, the correlation of the EPEr from a large whole mount prostatectomy series was determined with respect to the needle biopsy and prostatectomy specimen findings...
  56. doi request reprint Making anatomic terminology of the prostate and contiguous structures clinically useful: historical review and suggestions for revision in the 21st century
    Robert P Myers
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Clin Anat 23:18-29. 2010
    ..Finally, we provide a new table of terms for the prostate with recommended amendments and deletions to existing official nomenclature as contained in the 1998 Terminologia Anatomica...
  57. doi request reprint Histological subtype is an independent predictor of outcome for patients with renal cell carcinoma
    Bradley C Leibovich
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 183:1309-15. 2010
    ..We examined the significance of histological subtype on progression to distant metastasis and cancer specific death after nephrectomy...
  58. doi request reprint Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma
    Mahul B Amin
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 33:384-92. 2009
    ..In light of the distinctive clinicopathologic features and a low but definite metastatic potential, this unique subtype of renal cell carcinoma deserves formal recognition in the contemporary classification of renal neoplasms...
  59. doi request reprint The ability of biomarkers to predict systemic progression in men with high-risk prostate cancer treated surgically is dependent on ERG status
    R Jeffrey Karnes
    Department of Urology, Laboratory Medicine and Pathology, Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer Res 70:8994-9002. 2010
    ..In addition, although patient numbers are small, the response to adjuvant androgen deprivation therapy is associated with ERG status, showing more significant treatment effect in ERG(+) patients...
  60. ncbi request reprint High expression levels of survivin protein independently predict a poor outcome for patients who undergo surgery for clear cell renal cell carcinoma
    Alexander S Parker
    Department of Urology, Mayo Clinic College of Medicine, Jacksonville, Florida, USA
    Cancer 107:37-45. 2006
    ..What remained in question was whether survivin expression at the protein level is an independent predictor of disease progression and cancer-specific survival...
  61. ncbi request reprint Is renal sinus fat invasion the same as perinephric fat invasion for pT3a renal cell carcinoma?
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 174:1218-21. 2005
    ..We investigated the prognostic significance of each of these pathological features using a cohort of pT3a patients...
  62. ncbi request reprint Adenomatoid tumor of the adrenal gland: a clinicopathologic study of five cases and review of the literature
    Phillip A Isotalo
    Department of Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Surg Pathol 27:969-77. 2003
    ..6%). In three cases with clinical follow-up, no recurrence or metastases occurred. Adrenal gland adenomatoid tumors are morphologically and immunophenotypically identical to adenomatoid tumors of the genital tract and appear benign...
  63. ncbi request reprint The Mayo Clinic experience with surgical management, complications and outcome for patients with renal cell carcinoma and venous tumour thrombus
    Michael L Blute
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    BJU Int 94:33-41. 2004
    ..To report the surgical management, complications and outcomes over three decades by tumour thrombus level for patients with renal cell carcinoma (RCC) and renal venous extension, as surgery is the most effective treatment...
  64. ncbi request reprint Pathologic T1 clear cell renal cell carcinoma: insulin-like growth factor-I receptor expression and disease-specific survival
    Alexander S Parker
    Department of Urology, Mayo College of Medicine, Jacksonville, Florida 32224, USA
    Cancer 100:2577-82. 2004
    ..The authors conducted a case-cohort investigation to examine the association of insulin-like growth factor I receptor (IGF-IR) expression and disease-specific survival in patients who underwent surgery for pT1 CC-RCC...
  65. ncbi request reprint The cytoskeleton differentially localizes the early growth response gene-1 protein in cancer and benign cells of the prostate
    Gloria R Mora
    Department of Urology Research, Mayo Clinic, Rochester, MN 55905, USA
    Mol Cancer Res 2:115-28. 2004
    ..Thus, we add the novel concept that microtubules regulate EGR-1 localization in benign prostate cells but not in malignant prostate cells...
  66. ncbi request reprint Nephron sparing surgery for appropriately selected renal cell carcinoma between 4 and 7 cm results in outcome similar to radical nephrectomy
    Bradley C Leibovich
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 171:1066-70. 2004
    ..We compared outcomes between patients treated with nephron sparing surgery (NSS) without imperative indications for renal preservation and radical nephrectomy (RN) for 4 to 7 cm renal cell carcinoma (RCC)...
  67. ncbi request reprint Smooth muscle neoplasms of the urinary bladder: a clinicopathologic comparison of leiomyoma and leiomyosarcoma
    Scott A Martin
    Department of Pathology and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Surg Pathol 26:292-300. 2002
    ..In addition, the diagnosis of urinary bladder leiomyoma should be reserved for noninfiltrative smooth muscle tumors lacking mitotic activity, cytologic atypia, and necrosis...
  68. ncbi request reprint Perineural invasion and MIB-1 positivity in addition to Gleason score are significant preoperative predictors of progression after radical retropubic prostatectomy for prostate cancer
    Thomas J Sebo
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Surg Pathol 26:431-9. 2002
    ..Cancer progression models that include serum prostate specific antigen and clinical stage may require revision to incorporate perineural invasion and MIB-1 proliferative activity in addition to Gleason score...
  69. ncbi request reprint Cysteine-rich secretory protein-3: a potential biomarker for prostate cancer
    Farhad Kosari
    Division of Experimental Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 11:1419-26. 2002
    ..These findings suggest that CRISP-3 is a potential biomarker for prostate cancer...
  70. ncbi request reprint Prediction of progression after radical nephrectomy for patients with clear cell renal cell carcinoma: a stratification tool for prospective clinical trials
    Bradley C Leibovich
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 97:1663-71. 2003
    ....
  71. ncbi request reprint Transitional cell carcinoma of the urinary bladder with regional lymph node involvement treated by cystectomy: clinicopathologic features associated with outcome
    Igor Frank
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 97:2425-31. 2003
    ..However, some patients are cured by radical cystectomy alone. The goal of this study was to identify predictors of survival in this cohort...
  72. ncbi request reprint A protocol for performing extended lymph node dissection using primary tumor pathological features for patients treated with radical nephrectomy for clear cell renal cell carcinoma
    Michael L Blute
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 172:465-9. 2004
    ....
  73. ncbi request reprint Loss of expression of von Hippel-Lindau tumor suppressor protein associated with improved survival in patients with early-stage clear cell renal cell carcinoma
    Alexander S Parker
    Department of Urology, Mayo Clinic Jacksonville, Jacksonville, Florida 32224, USA
    Urology 65:1090-5. 2005
    ..Recent data have suggested that somatic mutations of the VHL tumor suppressor gene are associated with better cancer-specific survival in patients with CC-RCC...
  74. ncbi request reprint Independent validation of the 2002 American Joint Committee on cancer primary tumor classification for renal cell carcinoma using a large, single institution cohort
    Igor Frank
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota, USA
    J Urol 173:1889-92. 2005
    ..In the current study we evaluated the 2002 primary tumor classification and compared its predictive ability with that of the 1997 classification...
  75. ncbi request reprint Should direct ipsilateral adrenal invasion from renal cell carcinoma be classified as pT3a?
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 173:918-21. 2005
    ..In the current study we evaluated the association of direct ipsilateral adrenal invasion with outcome to determine if reclassification of these tumors as pT4 would improve the accuracy of the current tumor classification...
  76. ncbi request reprint Cancer specific survival for patients with pT3 renal cell carcinoma-can the 2002 primary tumor classification be improved?
    Bradley C Leibovich
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 173:716-9. 2005
    ..We evaluated the association of tumor thrombus level and fat invasion with outcome to determine if further subclassification would improve the prognostic accuracy of the current classification...
  77. ncbi request reprint pT2 classification for renal cell carcinoma. Can its accuracy be improved?
    Igor Frank
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 173:380-4. 2005
    ..In this study we determined whether a size cutoff point exists within pT2 tumors and whether such subclassification would further improve the accuracy of the current tumor classification...
  78. ncbi request reprint Prognostic value of p53 and MIB-1 in transitional cell carcinoma of the urinary bladder with regional lymph node involvement
    Igor Frank
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer 101:1803-8. 2004
    ..The objective of this study was to assess the ability of these markers to predict disease-associated outcomes and response to chemotherapy in a cohort of patients with LN-positive TCC...
  79. ncbi request reprint Contralateral adrenal metastasis of renal cell carcinoma: treatment, outcome and a review
    W K Lau
    Department of Urology, Mayo Clinic, Rochester, Minnesota, USA
    BJU Int 91:775-9. 2003
    ..5% of patients with metastatic RCC at autopsy, and the role of resecting metastatic RCC at this site is not well defined...
  80. ncbi request reprint Juxtaglomerular cell tumor: a clinicopathologic study of four cases and review of the literature
    S A Martin
    Department of Pathology and Laboratory Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Am J Clin Pathol 116:854-63. 2001
    ..There were no recurrences or metastases. The characteristic clinical and morphologic features of juxtaglomerular cell tumor permit distinction from renal hemangiopericytoma and other renal tumors...
  81. ncbi request reprint Associations with contralateral recurrence following nephrectomy for renal cell carcinoma using a cohort of 2,352 patients
    Ahmad H Bani-Hani
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 173:391-4. 2005
    ..We determined the incidence of and factors associated with the development of renal cell carcinoma (RCC) in the contralateral kidney after nephrectomy for localized RCC...
  82. ncbi request reprint PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of Bcl-2 expression
    H Huang
    Department of Urology Research, Mayo Foundation, Rochester, Minnesota 55905, USA
    J Biol Chem 276:38830-6. 2001
    ..These findings suggest that the PTEN gene and its regulated pathway are potential therapeutic targets in prostate cancer...
  83. ncbi request reprint Transitional cell carcinoma of the bladder mimicking recurrent paget's disease of the vulva: report of two cases, with one occurring in a myocutaneous flap
    C H Boardman
    Department of Obstetrics and Gynecology, Division of Anatomic Pathology, 200 First Street SW, Rochester, Minnesota, 55905, USA
    Gynecol Oncol 82:200-4. 2001
    ..CONCLUSION: If the history of the patient includes transitional cell carcinoma of the bladder and vulvar Paget's disease, histologic evaluation is needed for accurate diagnosis and proper treatment...
  84. pmc Comparison of digital image analysis versus visual assessment to assess survivin expression as an independent predictor of survival for patients with clear cell renal cell carcinoma
    Alexander S Parker
    Department of Urology, Mayo Clinic College of Medicine, Jacksonville, FL 32224, USA
    Hum Pathol 39:1176-84. 2008
    ..Thus, visual assessment represents an economical, widely available, and reliable method to assess survivin as a predictor of clear cell renal cell carcinoma patient outcomes...
  85. ncbi request reprint Comparison of presentation and outcome for patients 18 to 40 and 60 to 70 years old with solid renal masses
    Michael D Gillett
    Division of Urology, Southern Illinois University, Springfield, Illinois, USA
    J Urol 173:1893-6. 2005
    ..These factors likely contributed to improved cancer specific survival for younger patients...
  86. ncbi request reprint Tumor-infiltrating Foxp3-CD4+CD25+ T cells predict poor survival in renal cell carcinoma
    Sameer A Siddiqui
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Clin Cancer Res 13:2075-81. 2007
    ..We tested for the presence of putative Tregs within renal cell carcinoma (RCC) tumors...
  87. ncbi request reprint Surgical resection provides excellent outcomes for patients with cystic clear cell renal cell carcinoma
    W Scott Webster
    Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Urology 70:900-4; discussion 904. 2007
    ..However, long-term outcome data are lacking. We reviewed our experience with RCC and report on pathologic features and patient outcome associated with the cystic variant...
  88. ncbi request reprint Radical nephrectomy for pT1a renal masses may be associated with decreased overall survival compared with partial nephrectomy
    R Houston Thompson
    Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota, USA
    J Urol 179:468-71; discussion 472-3. 2008
    ..We reviewed our surgical experience with small renal tumors, comparing overall survival in patients treated with radical and partial nephrectomy...
  89. ncbi request reprint Frequent microsatellite instability in sporadic tumors of the upper urinary tract
    Arndt Hartmann
    Institute of Pathology, University of Regensburg, 93042 Regensburg, Germany
    Cancer Res 62:6796-802. 2002
    ....
  90. ncbi request reprint Expression of insulin-like growth factor I receptor and survival in patients with clear cell renal cell carcinoma
    Alexander Parker
    Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Urol 170:420-4. 2003
    ..Recent studies suggest that the insulin-like growth factor-I receptor (IGF-IR) may have prognostic value for patients with CC-RCC...
  91. doi request reprint Re: Location of extrarenal tumor extension does not impact survival of patients with pT3a renal cell carcinoma. V. Margulis, P. Tamboli, S. F. Matin, M. Meisner, D. A. Swanson and C. G. Wood. J Urol 2007; 178: 1878-1882
    R Houston Thompson
    J Urol 180:409; author reply 409-10. 2008
  92. ncbi request reprint Multiple ipsilateral renal tumors discovered at planned nephron sparing surgery: importance of tumor histology and risk of metachronous recurrence
    Michael L Blute
    Department of Urology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Urol 170:760-3. 2003
    ..We determined the outcome for patients treated with NSS or radical nephrectomy (RN)...