Research Topics
| S T ChariSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Pancreatic mucinous cystic neoplasm defined by ovarian stroma: demographics, clinical features, and prevalence of cancerRaghuram P Reddy
Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, Minnesota, USA
Clin Gastroenterol Hepatol 2:1026-31. 2004..These observations suggest that ovarian stroma should be used as the defining criterion for diagnosing MCN...
Diagnosis of autoimmune pancreatitis using its five cardinal features: introducing the Mayo Clinic's HISORt criteriaSuresh T Chari
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN, 55905, USA
J Gastroenterol 42:39-41. 2007..A combination of the HISORt criteria can be used to definitively diagnose a wide spectrum of manifestations of AIP...
Immunoglobulin G4-associated cholangitis: clinical profile and response to therapyAmaar Ghazale
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Gastroenterology 134:706-15. 2008..We describe clinical features, treatment response, and predictors of relapse in IAC and compare relapse rates in IAC with intrapancreatic vs proximal bile duct strictures...
Diabetes and pancreatic cancerT Muniraj
Yale University School of Medicine, New Haven, CT, USA
Minerva Gastroenterol Dietol 58:331-45. 2012..However, to screen new-onset diabetes for pancreatic cancer, additional markers are needed that can distinguish pancreatic cancer-associated diabetes from type 2 diabetes...
Islet amyloid polypeptide is not a satisfactory marker for detecting pancreatic cancerS T Chari
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
Gastroenterology 121:640-5. 2001....
Probability of pancreatic cancer following diabetes: a population-based studySuresh T Chari
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Rochester, Minnesota 55905, USA
Gastroenterology 129:504-11. 2005..Although diabetes occurs frequently in pancreatic cancer, the value of new-onset diabetes as a marker of underlying pancreatic cancer is unknown...
Is magnetic resonance cholangiography of clinical value in the diagnosis and treatment of gallstone pancreatitis?Suresh T Chari
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA
Nat Clin Pract Gastroenterol Hepatol 2:170-1. 2005
A diagnostic strategy to distinguish autoimmune pancreatitis from pancreatic cancerSuresh T Chari
Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Clin Gastroenterol Hepatol 7:1097-103. 2009..Autoimmune pancreatitis (AIP) and pancreatic cancer (PaC) have similar presentations; a diagnostic strategy is needed to distinguish the 2 diseases...
Pancreatic cancer-associated diabetes mellitus: prevalence and temporal association with diagnosis of cancerSuresh T Chari
Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Gastroenterology 134:95-101. 2008..The temporal association between diabetes mellitus and pancreatic cancer is poorly understood. We compared temporal patterns in diabetes prevalence in pancreatic cancer and controls...
Detecting early pancreatic cancer: problems and prospectsSuresh T Chari
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Semin Oncol 34:284-94. 2007..Although much work still needs to be done, the developments in the field provide us with hope that screening for early pancreatic cancer could become a reality in the not-so-distant future...
Histopathologic and clinical subtypes of autoimmune pancreatitis: the Honolulu consensus documentSuresh T Chari
Mayo Clinic, Rochester, MN, USA
Pancreas 39:549-54. 2010..Whereas most experts agreed that the entities should be referred to as type 1 and type 2 AIP, respectively, others had concerns regarding use of the term "autoimmune" to describe IDCP...
Histopathologic and clinical subtypes of autoimmune pancreatitis: the honolulu consensus documentSuresh T Chari
Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Pancreatology 10:664-72. 2010..While most experts agreed that the entities should be referred to as type 1 and type 2 AIP, respectively, others had concerns regarding use of the term 'autoimmune' to describe IDCP. and IAP...
Study of recurrence after surgical resection of intraductal papillary mucinous neoplasm of the pancreasSuresh T Chari
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
Gastroenterology 123:1500-7. 2002....
Beta-cell function and insulin resistance evaluated by HOMA in pancreatic cancer subjects with varying degrees of glucose intoleranceSuresh T Chari
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA
Pancreatology 5:229-33. 2005..To gain insights into pathogenesis of pancreatic cancer-associated diabetes...
Branch duct intraductal papillary mucinous neoplasm of the pancreas in solid organ transplant recipientsKanwar Rupinder S Gill
Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida 32224, USA
Am J Gastroenterol 104:1256-61. 2009..Recent studies show that IPMN-Br without consensus indications for resection (CIR) can be followed conservatively. We analyzed the course of IPMN-Br in patients with and without solid organ transplant...
Disconnected pancreatic duct syndrome in severe acute pancreatitis: clinical and imaging characteristics and outcomes in a cohort of 31 casesMario Pelaez-Luna
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Gastrointest Endosc 68:91-7. 2008..Information regarding the natural history, clinical characteristics, and outcomes of disconnected pancreatic duct syndrome (DPDS) is limited...
IgG4-positive plasma cell infiltration in the diagnosis of autoimmune pancreatitisLizhi Zhang
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
Mod Pathol 20:23-8. 2007..We rarely see IgG4 staining in patients with chronic alcoholic pancreatitis and pancreatic ductal adenocarcinoma. IgG4-positive plasma cells are a useful marker for the tissue diagnosis of autoimmune pancreatitis...
Update on the diagnosis and treatment of autoimmune pancreatitisAmaar H Ghazale
Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA
Curr Gastroenterol Rep 10:115-21. 2008..This in turn has resulted in the avoidance of unnecessary surgical procedures for suspected malignancy. This article reviews recent updates in the diagnosis and treatment of autoimmune pancreatitis...
Misdiagnosis of autoimmune pancreatitis: a caution to cliniciansTimothy B Gardner
Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Gastroenterol 104:1620-3. 2009..Our purpose is to highlight this growing clinical problem and to reinforce the use of published guidelines for the diagnosis and management of AIP...
Autoimmune pancreatitisRahul Pannala
Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Curr Opin Gastroenterol 24:591-6. 2008..Autoimmune pancreatitis (AIP) is an increasingly recognized clinical condition. Our objective is to provide a concise review of the advances in the past year in our understanding of AIP...
Dual-phase CT of autoimmune pancreatitis: a multireader studyNaoki Takahashi
Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
AJR Am J Roentgenol 190:280-6. 2008..The purpose of this study was to identify findings that aid in differentiating autoimmune pancreatitis from pancreatic carcinoma using dual-phase CT...
Initial evaluation of the efficacy and safety of endoscopic ultrasound-guided direct Ganglia neurolysis and blockMichael J Levy
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Am J Gastroenterol 103:98-103. 2008..The recent recognition that celiac ganglia can be visualized by endoscopic ultrasound (EUS) now allows direct injection into celiac ganglia for neurolysis (CGN) and block (CGB)...
Resectability of presymptomatic pancreatic cancer and its relationship to onset of diabetes: a retrospective review of CT scans and fasting glucose values prior to diagnosisMario Pelaez Luna
Department of Internal Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Am J Gastroenterol 102:2157-63. 2007..It is unclear if the cancer is resectable at the onset of diabetes. We (a) determined the resectability of pancreatic cancer on abdominal CT scans done prior to clinical diagnosis and (b) correlated resectability with onset of diabetes...
Autoimmune pancreatitis: differentiation from pancreatic carcinoma and normal pancreas on the basis of enhancement characteristics at dual-phase CTNaoki Takahashi
Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
AJR Am J Roentgenol 193:479-84. 2009..The purposes of this study were to define the pancreatic enhancement of autoimmune pancreatitis at dual-phase CT and to compare it with that of pancreatic carcinoma and a normal pancreas...
Diagnosis and treatment of autoimmune pancreatitisAravind Sugumar
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55901, USA
Curr Opin Gastroenterol 26:513-8. 2010..To summarize the existing knowledge of autoimmune pancreatitis (AIP) and to review the progress made in the diagnosis and treatment of AIP in the past year...
The effect of age on hospital outcomes in severe acute pancreatitisTimothy B Gardner
Pancreas Clinic, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minn, USA
Pancreatology 8:265-70. 2008..We evaluated clinical outcomes, including in-hospital mortality and long-term disease stigmata, in elderly patients admitted with severe acute pancreatitis...
Calcifying obstructive pancreatitis: a study of intraductal papillary mucinous neoplasm associated with pancreatic calcificationMauricio Zapiach
Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, Rochester, Minnesota 55905, USA
Clin Gastroenterol Hepatol 2:57-63. 2004....
Autoimmune pancreatitisLuis P Lara
Department of Internal Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Curr Gastroenterol Rep 7:101-6. 2005..Here we review the clinical, serologic, radiologic, and histologic features of autoimmune pancreatitis...
Value of serum IgG4 in the diagnosis of autoimmune pancreatitis and in distinguishing it from pancreatic cancerAmaar Ghazale
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Am J Gastroenterol 102:1646-53. 2007..To determine the sensitivity and specificity of elevated serum IgG4 level for the diagnosis of autoimmune pancreatitis (AIP) and its ability to distinguish AIP from pancreatic cancer, its main differential diagnosis...
Low mortality and high morbidity in severe acute pancreatitis without organ failure: a case for revising the Atlanta classification to include "moderately severe acute pancreatitis"Santhi Swaroop Vege
Department of Medicine, Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Gastroenterol 104:710-5. 2009..Organ failure (OF) is a main cause of death in severe acute pancreatitis (SAP). Our primary aim was to evaluate the morbidity and mortality of patients admitted with SAP with no OF (NOF), single OF (SOF), and multiple (> or =2) OF (MOF)...
Possible association between IgG4-associated systemic disease with or without autoimmune pancreatitis and non-Hodgkin lymphomaNaoki Takahashi
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
Pancreas 38:523-6. 2009..IgG4-associated systemic disease (ISD) is a multiorgan fibroinflammatory disorder whose pancreatic manifestation is called autoimmune pancreatitis (AIP). We describe 3 patients who developed non-Hodgkin lymphoma during the follow-up of ISD...
Endoscopic ultrasound-guided trucut biopsy of the cyst wall for diagnosing cystic pancreatic tumorsMichael J Levy
Division of Gastroenterology and Hepatology, Mayo Clinic School of Medicine, Rochester, Minnesota 55905, USA
Clin Gastroenterol Hepatol 3:974-9. 2005..The aim of this study was to determine whether the tissue obtained by endoscopic ultrasound-guided trucut biopsy (EUS TCB) is sufficient for histologic diagnosis of cystic pancreatic tumors (CPTs)...
Severe acute pancreatitisVege Santhi Swaroop
Division of General Internal Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
JAMA 291:2865-8. 2004
EUS-guided trucut biopsy in establishing autoimmune pancreatitis as the cause of obstructive jaundiceMichael J Levy
Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Gastrointest Endosc 61:467-72. 2005..Doing so helps guide management and may help to avoid unnecessary surgery. Prospective studies are needed to verify these findings and to more clearly define the role of EUS TCB in these patients...
Experience with 208 resections for intraductal papillary mucinous neoplasm of the pancreasThomas Schnelldorfer
Division of Gastroenterologic and General Surgery, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Arch Surg 143:639-46; discussion 646. 2008..Intraductal papillary mucinous neoplasm (IPMN) is an increasingly recognized disease of the pancreas. We report our experience with pancreatic resection for IPMN...
Rituximab therapy for refractory biliary strictures in immunoglobulin G4-associated cholangitisMark Topazian
Miles and Shirley Fiterman Center for Digestive Diseases, Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55906, USA
Clin Gastroenterol Hepatol 6:364-6. 2008..Biliary strictures occur in a third of patients with autoimmune pancreatitis and have been termed immunoglobulin G subclass 4 (IgG4) associated cholangitis (IAC). IAC often responds to steroid therapy...
Endoscopic retrograde cholangiopancreatography-induced severe acute pancreatitisSanthi Swaroop Vege
Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
Pancreatology 6:527-30. 2006..Compared to other causes, higher morbidity and mortality have been reported in ERCP-induced acute pancreatitis. We undertook this study to determine the differences between ESAP and SAP due to other causes (OSAP)...
Outcomes of intra-abdominal fungal vs. bacterial infections in severe acute pancreatitisSanthi Swaroop Vege
Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
Am J Gastroenterol 104:2065-70. 2009..We aimed to compare the morbidity and mortality of IFI compared with intra-abdominal bacterial infection (IBI) and no intra-abdominal infection (NII) in patients with SAP...
Intraductal papillary mucinous neoplasm: did it exist prior to 1980?Matthew K Tollefson
Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA
Pancreas 26:e55-8. 2003..Intraductal papillary mucinous neoplasm (IPMN) of the pancreas was first reported in 1982. It is not clear whether the appearance of this neoplasm is a new epidemic or an old disease previously overlooked...
Distinguishing pancreatic cancer from autoimmune pancreatitisAravind Sugumar
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Curr Gastroenterol Rep 12:91-7. 2010..The two strategies reflect differences in clinical practice and local preferences in the use of certain diagnostic tests. However, both strategies require thorough familiarity with the diseases and the tests being used...
IgG4+ plasma cell infiltrates in liver explants with primary sclerosing cholangitisLizhi Zhang
Department of Laboratory Medicine, Mayo Clinic, Rochester, MN 55905, USA
Am J Surg Pathol 34:88-94. 2010..PSC with tissue IgG4 positivity has a more aggressive clinical course manifested by shorter time to transplant and a higher likelihood of recurrence than IgG4 negative PSC...
Diagnosis of autoimmune pancreatitis: the Mayo Clinic experienceSuresh T Chari
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Clin Gastroenterol Hepatol 4:1010-6; quiz 934. 2006..AIP has unique histologic features associated with infiltration of tissues of affected organs with abundant IgG4-positive cells. We propose expanded diagnostic criteria for AIP with a cohort of histologically confirmed AIP...
Renal involvement in patients with autoimmune pancreatitis: CT and MR imaging findingsNaoki Takahashi
Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Radiology 242:791-801. 2007..To retrospectively evaluate computed tomographic (CT) and magnetic resonance (MR) imaging renal findings at clinical presentation, during treatment, and at follow-up in patients with autoimmune pancreatitis (AIP)...
Treatment options for hepatobiliary and pancreatic cancerSteven R Alberts
Division of Medical Oncology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Mayo Clin Proc 82:628-37. 2007..For pancreatic cancer, surgery, radiation, and systemic therapy all have potential roles. This review provides an updated summary of diagnosis and assessment together with treatment options for this group of cancers...
Chronic pancreatitis: focal pancreatitis or cancer? Is there a role for FNA/biopsy? Autoimmune pancreatitisM J Levy
Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Endoscopy 38:S30-5. 2006
Inflammatory bowel disease in the setting of autoimmune pancreatitisKarthik Ravi
Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
Inflamm Bowel Dis 15:1326-30. 2009..Despite scattered case reports, the prevalence of inflammatory bowel disease (IBD) in patients with autoimmune pancreatitis (AIP) is unknown. We sought to better characterize the putative association between the conditions...
75-year-old man with abdominal pain and weight lossMichael D Leise
Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Mayo Clin Proc 83:1161-4. 2008
Idiopathic tumefactive chronic pancreatitis: clinical profile, histology, and natural history after resectionDhiraj Yadav
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA
Clin Gastroenterol Hepatol 1:129-35. 2003..Resection of mass prevents recurrence of symptoms in idiopathic TCP...
Eosinophilia and allergic disorders in autoimmune pancreatitisRaghuwansh P Sah
Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA
Am J Gastroenterol 105:2485-91. 2010..In autoimmune pancreatitis (AIP), the prevalence, interrelationships, and significance of peripheral eosinophilia, allergic disorders, and eosinophil infiltration in the pancreas remain unclear...
New-onset diabetes: a potential clue to the early diagnosis of pancreatic cancerRahul Pannala
Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, Rochester, MN, USA
Lancet Oncol 10:88-95. 2009....
Autoimmune pancreatitis: pancreatic and extrapancreatic imaging findingsKale D Bodily
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
AJR Am J Roentgenol 192:431-7. 2009..It is important for radiologists to understand both the pancreatic and extrapancreatic imaging findings of autoimmune pancreatitis to make accurate and timely diagnoses...
Prevalence, diagnosis, and profile of autoimmune pancreatitis presenting with features of acute or chronic pancreatitisRaghuwansh P Sah
Fiterman Center for Digestive Diseases, Mayo Clinic, Rochester, Minnesota, USA
Clin Gastroenterol Hepatol 8:91-6. 2010..We explored the clinical profiles and relationship between these diseases...
Distinctive pulmonary histopathology with increased IgG4-positive plasma cells in patients with autoimmune pancreatitis: report of 6 and 12 cases with similar histopathologyBijayee Shrestha
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
Am J Surg Pathol 33:1450-62. 2009..The significance of increased IgG4+ cells in high proportion of RD cases merits further study as does overlap of RD and IgG4 disease...
Temporal association of changes in fasting blood glucose and body mass index with diagnosis of pancreatic cancerRahul Pannala
Department of Gastroenterology and Hepatology, Fiterman Center for Digestive Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Gastroenterol 104:2318-25. 2009..Although the association between diabetes mellitus (DM) and pancreatic cancer is well described, temporal patterns of changes in fasting blood glucose (FBG) and body mass index (BMI) before pancreatic cancer diagnosis are not known...
Acute pancreatitis in patients with Crohn's disease: clinical features and outcomesPicha Moolsintong
Department of Internal Medicine and Division of Gastroenterology and Hepatology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
Inflamm Bowel Dis 11:1080-4. 2005..A small proportion of patients remained idiopathic...
Prevalence and clinical profile of pancreatic cancer-associated diabetes mellitusRahul Pannala
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota
Gastroenterology 134:981-7. 2008..Information on the clinical profile of pancreatic cancer (PaC) associated diabetes (DM) is limited. We compared the prevalence and clinical characteristics of DM in subjects with and without PaC...
Recent advances in autoimmune pancreatitisD H Park
Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, Rochester, MN 55905, USA
Gut 58:1680-9. 2009..Recent development of animal models of AIP will help improve our understanding of the pathogenesis of these newly described forms of chronic pancreatitis...
Endoscopic ultrasonography and pancreatic cancerT B Gardner
Miles and Shirley Fiterman Centre for Digestive Diseases, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Minerva Gastroenterol Dietol 54:161-76. 2008..Finally, exciting new developments suggest the potential of EUS as a therapeutic tool, both for the management of pain from pancreatic cancer and as a novel therapeutic-delivery device...
Chronic pancreatitis: classification, relationship to acute pancreatitis, and early diagnosisSuresh T Chari
Division of Gastroenterology and Hepatology, 200 First St SW, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Gastroenterol 42:58-9. 2007
Quality-of-life after total pancreatectomy: is it really that bad on long-term follow-up?Brian J Billings
Department of Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
J Gastrointest Surg 9:1059-66; discussion 1066-7. 2005..QoL after TP is decreased compared with age- and gender-matched controls but not with diabetes from other causes; however, the changes are not overwhelming. TP should remain a viable option but in selected patients...
Do consensus indications for resection in branch duct intraductal papillary mucinous neoplasm predict malignancy? A study of 147 patientsMario Pelaez-Luna
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Am J Gastroenterol 102:1759-64. 2007..Among a cohort of patients with IPMN-Br we determined if the consensus IR (CIR), presence of multifocal IPMN-Br, or growth of cyst size on follow-up predict malignancy...
Distinguishing pancreatic cancer from autoimmune pancreatitis: a comparison of two strategiesAravind Sugumar
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55901, USA
Clin Gastroenterol Hepatol 7:S59-62. 2009..Additionally, differences in clinical practice and local preference in the use of certain diagnostic tests need to be considered while adopting either strategy...
Autoimmune pancreatitisTimothy B Gardner
Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, Rochester, MN 55905, USA
Gastroenterol Clin North Am 37:439-60, vii. 2008..Although still a rare disease, autoimmune pancreatitis is increasingly becoming recognized clinically, leading to evolution in the understanding of its prognosis, clinical characteristics, and treatment...
Asymptomatic solid pseudopapillary neoplasm of the pancreasFerga C Gleeson
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Clin Gastroenterol Hepatol 6:A22. 2008
Optimising corticosteroid treatment for autoimmune pancreatitisAmaar Ghazale
Division of Gastroenterology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Gut 56:1650-2. 2007
Long-term survival and prognostic indicators in small (<or=2 cm) pancreatic cancerSupot Pongprasobchai
Division of Gastroenterology, Mayo Clinic, Rochester, MN 55905, USA
Pancreatology 8:587-92. 2008..In a matched analysis, we investigated clinical, histopathological, and survival characteristics of small (<or=2 cm) pancreatic cancer (PaC) as compared to large PaC...
Immunoglobulin G4 associated cholangitis: description of an emerging clinical entity based on review of the literatureEinar Bjornsson
Department of Internal Medicine, Division of Gastroenterology and Hepatology, Sahlgrenska University Hospital, SE 413 45 Gothenburg, Sweden
Hepatology 45:1547-54. 2007
Conservative management of infected necrosis complicating severe acute pancreatitisDouglas G Adler
Department of Internal Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55901, USA
Am J Gastroenterol 98:98-103. 2003..High risk necrosectomy can, in some instances, be delayed or avoided entirely...
Endoscopic retrograde pancreatography criteria to diagnose autoimmune pancreatitis: an international multicentre studyAravind Sugumar
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Gut 60:666-70. 2011..Characteristic pancreatic duct changes on endoscopic retrograde pancreatography (ERP) have been described in autoimmune pancreatitis (AIP). The performance characteristics of ERP to diagnose AIP were determined...
Natural history of endocrine failure in tropical chronic pancreatitis: a longitudinal follow-up studyViswanathan Mohan
Madras Diabetes Research Foundation and Dr Mohans M V Diabetes Specialities Center, Gopalapuram, Chennai, India
J Gastroenterol Hepatol 20:1927-34. 2005..The aim of the present study was to determine the natural history of endocrine failure in TCP subjects without diabetes at baseline...
Current concepts in the treatment of autoimmune pancreatitisSuresh T Chari
JOP 8:1-3. 2007..The inflammatory component of the disease appears to resolve with steroid treatment, though relapses do occur. Here we briefly discuss the role of steroid therapy in the management of autoimmune pancreatitis...
Controversies in clinical pancreatology: management of acute idiopathic recurrent pancreatitisWilliam M Steinberg
Department of Medicine, George Washington University Medical Center, Washington, DC, USA
Pancreas 27:103-17. 2003
Can histopathology be the "Gold Standard" for diagnosing autoimmune pancreatitis?Suresh T Chari
Gastroenterology 129:2118-20; discussion 2120. 2005
Autoimmune pancreatitis, Part II: the relapseSuresh T Chari
Gastroenterology 134:625-8. 2008
Cyst fluid analysis to diagnose pancreatic cystic lesions: an as yet unfulfilled promiseMario Pelaez-Luna
Gastroenterology 130:1007-9; discussion 1009. 2006
Management of pancreatic massesDaniel Wolfson
Department of Medicine, George Washington University Medical Center, Washington, DC, USA
Pancreas 31:203-17. 2005
Time interval between abnormalities seen on CT and the clinical diagnosis of pancreatic cancer: retrospective review of CT scans obtained before diagnosisSumana Gangi
University of Medicine and Dentistry of New Jersey, Newark, NJ, USA
AJR Am J Roentgenol 182:897-903. 2004..Pancreatic duct dilatation and cutoff are early findings associated with the development of pancreatic cancer and can be detected on CT with a high degree of reproducibility...
Expression and regulatory role of GAIP-interacting protein GIPC in pancreatic adenocarcinomaMichael H Muders
Department of Biochemistry and Molecular Biology, Mayo Clinic Cancer Center, Rochester, Minnesota 55905, USA
Cancer Res 66:10264-8. 2006..Taken together, our data suggest that GIPC is a central molecule for the stability of IGF-IR and could be a target for future therapy...
Diagnosis of pancreatic cancer using serum proteomic profilingSudeepa Bhattacharyya
Center for Orthopaedic Research, Department of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA
Neoplasia 6:674-86. 2004..These results suggest that high-throughput proteomics profiling has the capacity to provide new biomarkers for the early detection and diagnosis of PCa...
Controversies in clinical pancreatology: autoimmune pancreatitis: does it exist?Randall K Pearson
Department of Medicine, George Washington University Medical Center, Washington, DC, USA
Pancreas 27:1-13. 2003
Aberrant nuclear accumulation of glycogen synthase kinase-3beta in human pancreatic cancer: association with kinase activity and tumor dedifferentiationAndrei V Ougolkov
Division of Oncology Research, Gastrointestinal Unit, Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Clin Cancer Res 12:5074-81. 2006....
Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesisMartin E Fernandez-Zapico
Gastroenterology Research Unit, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Cancer Cell 7:39-49. 2005..Thus, the discovery of prooncogenic pathways regulated by Vav1 makes it an attractive target for therapeutic intervention...
Defective DNA mismatch repair in long-term (> or =3 years) survivors with pancreatic cancerJohn T Maple
Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, MN 55905, USA
Pancreatology 5:220-7; discussion 227-8. 2005..To determine if long-term survival in pancreatic cancer could be attributed to defective DNA MMR, we ascertained its prevalence in 35 pancreatic cancer patients who survived > or =3 years after surgery...
Research Grants
- Does Hyperglycemia Predict Pancreatic Cancer Diagnosis?Suresh Chari; Fiscal Year: 2006..The research described in this application is 100% relevant to pancreatic cancer. ..
