James Cerhan

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. pmc A pooled analysis of waist circumference and mortality in 650,000 adults
    James R Cerhan
    Division of Epidemiology, Mayo Clinic, Rochester, MN Electronic address
    Mayo Clin Proc 89:335-45. 2014
  2. pmc Residential proximity to industrial combustion facilities and risk of non-Hodgkin lymphoma: a case-control study
    Anjoeka Pronk
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD, USA
    Environ Health 12:20. 2013
  3. pmc A two-stage evaluation of genetic variation in immune and inflammation genes with risk of non-Hodgkin lymphoma identifies new susceptibility locus in 6p21.3 region
    James R Cerhan
    Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 21:1799-806. 2012
  4. pmc LIM domain only 2 protein expression, LMO2 germline genetic variation, and overall survival in diffuse large B-cell lymphoma in the pre-rituximab era
    James R Cerhan
    College of Medicine, Mayo Clinic, Rochester, MN, USA
    Leuk Lymphoma 53:1105-12. 2012
  5. pmc Spatial-temporal analysis of non-Hodgkin lymphoma in the NCI-SEER NHL case-control study
    David C Wheeler
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Bethesda, MD, USA
    Environ Health 10:63. 2011
  6. pmc Genetic variation in stromal proteins decorin and lumican with breast cancer: investigations in two case-control studies
    Linda E Kelemen
    Department of Population Health Research, Alberta Cancer Board, 1331 29th Street NW, Calgary, AB T2N 4N2, Canada
    Breast Cancer Res 10:R98. 2008
  7. pmc Genetic variation in tumor necrosis factor and the nuclear factor-kappaB canonical pathway and risk of non-Hodgkin's lymphoma
    James R Cerhan
    Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 1st Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 17:3161-9. 2008
  8. ncbi Association of aspirin and other non-steroidal anti-inflammatory drug use with incidence of non-Hodgkin lymphoma
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Int J Cancer 106:784-8. 2003
  9. ncbi Anthropometrics, physical activity, related medical conditions, and the risk of non-hodgkin lymphoma
    James R Cerhan
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Cancer Causes Control 16:1203-14. 2005
  10. ncbi Family history and prostate cancer risk in a population-based cohort of Iowa men
    J R Cerhan
    Department of Preventive Medicine, The University of Iowa College of Medicine, Iowa City 52242, USA
    Cancer Epidemiol Biomarkers Prev 8:53-60. 1999

Research Grants

  1. Immunogenetics of Non-Hodgkin Lymphoma Survival
    James Cerhan; Fiscal Year: 2002
  2. Molecular Epidemiology of NHL and CLL
    James R Cerhan; Fiscal Year: 2010
  3. Molecular Epidemiology of non-Hodgkin Lymphoma Survival
    James R Cerhan; Fiscal Year: 2010
  4. Molecular Epidemiology of NHL and CLL
    James Cerhan; Fiscal Year: 2009
  5. Molecular Epidemiology of non-Hodgkin Lymphoma Survival
    James Cerhan; Fiscal Year: 2009
  6. Molecular Epidemiology of NHL and CLL
    James Cerhan; Fiscal Year: 2007
  7. Immunogenetics of Non-Hodgkin Lymphoma Survival
    James Cerhan; Fiscal Year: 2006
  8. Molecular Epidemiology of NHL and CLL
    James Cerhan; Fiscal Year: 2006
  9. Immunogenetics of Non-Hodgkin Lymphoma Survival
    James Cerhan; Fiscal Year: 2005
  10. Molecular Epidemiology of NHL and CLL
    James Cerhan; Fiscal Year: 2005

Detail Information

Publications95

  1. pmc A pooled analysis of waist circumference and mortality in 650,000 adults
    James R Cerhan
    Division of Epidemiology, Mayo Clinic, Rochester, MN Electronic address
    Mayo Clin Proc 89:335-45. 2014
    ..To assess the independent effect of waist circumference on mortality across the entire body mass index (BMI) range and to estimate the loss in life expectancy related to a higher waist circumference...
  2. pmc Residential proximity to industrial combustion facilities and risk of non-Hodgkin lymphoma: a case-control study
    Anjoeka Pronk
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD, USA
    Environ Health 12:20. 2013
    ..The aim of our study was to evaluate residence near industrial combustion facilities and estimates of dioxin emissions in relation to NHL risk in the United States...
  3. pmc A two-stage evaluation of genetic variation in immune and inflammation genes with risk of non-Hodgkin lymphoma identifies new susceptibility locus in 6p21.3 region
    James R Cerhan
    Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 21:1799-806. 2012
    ..Non-Hodgkin lymphoma (NHL) is a malignancy of lymphocytes, and there is growing evidence for a role of germline genetic variation in immune genes in NHL etiology...
  4. pmc LIM domain only 2 protein expression, LMO2 germline genetic variation, and overall survival in diffuse large B-cell lymphoma in the pre-rituximab era
    James R Cerhan
    College of Medicine, Mayo Clinic, Rochester, MN, USA
    Leuk Lymphoma 53:1105-12. 2012
    ..In conclusion, germline genetic variation in LMO2 was associated with DLBCL prognosis and provided slightly stronger predictive ability relative to LMO2 IHC status...
  5. pmc Spatial-temporal analysis of non-Hodgkin lymphoma in the NCI-SEER NHL case-control study
    David C Wheeler
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Bethesda, MD, USA
    Environ Health 10:63. 2011
    ..Little is known about the etiology of non-Hodgkin lymphoma (NHL), or the latency period that might be relevant for environmental exposures, and there are no published spatial-temporal cluster studies of NHL...
  6. pmc Genetic variation in stromal proteins decorin and lumican with breast cancer: investigations in two case-control studies
    Linda E Kelemen
    Department of Population Health Research, Alberta Cancer Board, 1331 29th Street NW, Calgary, AB T2N 4N2, Canada
    Breast Cancer Res 10:R98. 2008
    ..Altered expression of decorin and lumican is associated with breast tumors. We hypothesized that genetic variation in the decorin (DCN) and lumican (LUM) genes may contribute to breast cancer...
  7. pmc Genetic variation in tumor necrosis factor and the nuclear factor-kappaB canonical pathway and risk of non-Hodgkin's lymphoma
    James R Cerhan
    Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 1st Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 17:3161-9. 2008
    ....
  8. ncbi Association of aspirin and other non-steroidal anti-inflammatory drug use with incidence of non-Hodgkin lymphoma
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Int J Cancer 106:784-8. 2003
    ..These data suggest that use of NSAIDs, either aspirin or other non-aspirin NSAIDs, are associated positively with risk of NHL, and that this association is independent of RA history...
  9. ncbi Anthropometrics, physical activity, related medical conditions, and the risk of non-hodgkin lymphoma
    James R Cerhan
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Cancer Causes Control 16:1203-14. 2005
    ..Physical inactivity increases the risk of obesity and of type 2 diabetes, but there are few data on the association of physical activity with risk of NHL...
  10. ncbi Family history and prostate cancer risk in a population-based cohort of Iowa men
    J R Cerhan
    Department of Preventive Medicine, The University of Iowa College of Medicine, Iowa City 52242, USA
    Cancer Epidemiol Biomarkers Prev 8:53-60. 1999
    ..These data also support the idea that a family history of breast cancer may also be a prostate cancer risk factor...
  11. ncbi Interaction of adolescent anthropometric characteristics and family history on breast cancer risk in a Historical Cohort Study of 426 families (USA)
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Cancer Causes Control 15:1-9. 2004
    ..To determine whether the association of adolescent anthropometric characteristics with breast cancer is modified by a family history of the disease...
  12. pmc Blood transfusion, anesthesia, surgery and risk of non-Hodgkin lymphoma in a population-based case-control study
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 5905, USA
    Int J Cancer 123:888-94. 2008
    ..Multiple surgical procedures and/or repeated administration of anesthesia have not been previously reported to be associated with risk of NHL and these exposures warrant further evaluation...
  13. ncbi Adherence to the AICR cancer prevention recommendations and subsequent morbidity and mortality in the Iowa Women's Health Study cohort
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 13:1114-20. 2004
    ....
  14. pmc Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival
    James R Cerhan
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Blood 109:5439-46. 2007
    ..Common variation in host immune genes warrants further evaluation as a promising class of prognostic factors in follicular lymphoma...
  15. ncbi Prenatal and perinatal correlates of adult mammographic breast density
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 14:1502-8. 2005
    ..We examined the hypothesis that those factors associated with higher levels of estrogen during pregnancy or shortly after birth are associated with higher mammographic breast density in adulthood...
  16. pmc Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma
    James R Cerhan
    Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Blood 110:4455-63. 2007
    ....
  17. pmc Risk of non-Hodgkin lymphoma in association with germline variation in complement genes
    James R Cerhan
    Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Br J Haematol 145:614-23. 2009
    ..015; OR = 0.68; 95% 0.56-0.84) remained noteworthy. Associations were similar for the common NHL subtypes. In summary, we provide evidence for a role of genetic variation in complement genes, particularly C5 and C9, and NHL risk...
  18. ncbi Antioxidant micronutrients and risk of rheumatoid arthritis in a cohort of older women
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Am J Epidemiol 157:345-54. 2003
    ..Intake of certain antioxidant micronutrients, particularly beta-cryptoxanthin and supplemental zinc, and possibly diets high in fruits and cruciferous vegetables, may be protective against the development of rheumatoid arthritis...
  19. ncbi Hormone replacement therapy and risk of non-hodgkin lymphoma and chronic lymphocytic leukemia
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 11:1466-71. 2002
    ..For diffuse NHL, 64% of the cases were nodal, and there was no association of HRT with either nodal or extra-nodal sites. These data suggest that HRT is a risk factor for follicular NHL but not for diffuse or small lymphocyte NHL or CLL...
  20. pmc Host genetics in follicular lymphoma
    James R Cerhan
    Division of Epidemiology, College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Best Pract Res Clin Haematol 24:121-34. 2011
    ..While the use of host genetics to identify individuals at high risk of FL or to predict FL treatment response and prognosis appears to be very promising, it is not yet ready for the clinic...
  21. ncbi Tea consumption and risk of cancer of the colon and rectum
    J R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Nutr Cancer 41:33-40. 2001
    ..0, 1.0, 1.1, and 0.4; P for trend = 0.3). These data do not support an overall association, either positive or negative, between tea consumption and risk of colon or rectal cancer in this Mid-western US population...
  22. ncbi Blood transfusion, alcohol use, and anthropometric risk factors for rheumatoid arthritis in older women
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Rheumatol 29:246-54. 2002
    ..To evaluate whether blood transfusion, alcohol use, or anthropometric characteristics are risk factors for rheumatoid arthritis (RA) in older women...
  23. ncbi Blood transfusions and risk of non-Hodgkin's lymphoma subtypes and chronic lymphocytic leukemia
    J R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 10:361-8. 2001
    ..Through 1997, 229 cases of NHL and 57 cases of CLL in the cohort were identified through linkage to the Iowa Surveillance, Epidemiology and End Results Cancer..
  24. ncbi Anthropometric characteristics, physical activity, and risk of non-Hodgkin's lymphoma subtypes and B-cell chronic lymphocytic leukemia: a prospective study
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Am J Epidemiol 156:527-35. 2002
    ..The opposite associations of body mass index with small lymphocytic lymphoma versus B-CLL may be a chance finding but, if confirmed, would suggest different etiologies for these malignancies...
  25. ncbi Twinship and risk of postmenopausal breast cancer
    J R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    J Natl Cancer Inst 92:261-5. 2000
    ..e., belonging to a twin pair) and the risk of breast cancer...
  26. ncbi Menstrual and reproductive factors and risk of non-Hodgkin lymphoma: the Iowa women's health study (United States)
    James R Cerhan
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Cancer Causes Control 13:131-6. 2002
    ..Endogenous sex hormones, particularly estrogens, modulate the immune system, and non-Hodgkin lymphoma (NHL) is a tumor that is related to immunologic status...
  27. pmc Evaluation of associations between common variation in mitotic regulatory pathways and risk of overall and high grade breast cancer
    Kristen N Stevens
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Breast Cancer Res Treat 129:617-22. 2011
    ..Further investigation in breast and other cancers are needed to understand the influence of inherited variation in mitotic genes on tumor grade and cancer risk...
  28. ncbi Postmenopausal cancer risk after self-reported endometriosis diagnosis in the Iowa Women's Health Study
    Janet E Olson
    Mayo Foundation, Health Sciences Research, Rochester, Minnesota 55905, USA
    Cancer 94:1612-8. 2002
    ..A recent study reported that women with a hospital discharge diagnosis of endometriosis were at increased risk of cancer at any site, breast cancer, ovarian cancer, and hematopoietic malignancies, especially non-Hodgkin lymphoma (NHL)...
  29. pmc Vegetables- and antioxidant-related nutrients, genetic susceptibility, and non-Hodgkin lymphoma risk
    Linda E Kelemen
    Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN, 55905, USA
    Cancer Causes Control 19:491-503. 2008
    ..Although most associations have not been examined previously with NHL, our results suggest the examined polymorphisms are not modifiers of the association between vegetable and zinc intakes and NHL risk...
  30. ncbi Does folate intake decrease risk of postmenopausal breast cancer among women with a family history?
    Thomas A Sellers
    Mayo Clinic Cancer Center, Rochester, MN 55905, USA
    Cancer Causes Control 15:113-20. 2004
    ..We examined whether the putative benefit extends to women with a family history (FH) of breast cancer using a cohort of 33,552 postmenopausal women aged 55-69 years in 1986...
  31. pmc No interaction of body mass index and smoking on diabetes mellitus risk in elderly women
    Michael W Cullen
    Nicotine Dependence Center, Primary Care Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Prev Med 48:74-8. 2009
    ..We sought to assess the interaction of smoking and body mass index (BMI) on diabetes risk...
  32. pmc Cigarette smoking and colorectal cancer risk by molecularly defined subtypes
    David Limsui
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Natl Cancer Inst 102:1012-22. 2010
    ..Because colorectal carcinogenesis is a heterogeneous process, we investigated whether cigarette smoking is differentially associated with molecularly defined subtypes of colorectal cancer...
  33. pmc Antioxidant intake from fruits, vegetables and other sources and risk of non-Hodgkin's lymphoma: the Iowa Women's Health Study
    Carrie A Thompson
    Department of Medicine, College of Medicine Mayo Clinic, Rochester, MN, USA
    Int J Cancer 126:992-1003. 2010
    ..In conclusion, these results support a role for vegetables, and perhaps fruits and associated antioxidants from food sources, as protective factors against the development of NHL and follicular lymphoma in particular...
  34. ncbi Association of aspirin and nonaspirin nonsteroidal anti-inflammatory drugs with cancer incidence and mortality
    Aditya Bardia
    Department of Internal Medicine, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
    J Natl Cancer Inst 99:881-9. 2007
    ..We evaluated associations between aspirin and nonaspirin NSAID use with cancer incidence and mortality stratified by smoking history in the Iowa Women's Health Study, a prospective cohort of postmenopausal women...
  35. ncbi Evaluation of genetic variations in the androgen and estrogen metabolic pathways as risk factors for sporadic and familial prostate cancer
    Julie M Cunningham
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 16:969-78. 2007
    ..Given that the point estimates for the odds ratio for each of these polymorphisms are <2.0, much larger sample sizes will be required for confirmation...
  36. ncbi Recreational physical activity and risk of postmenopausal breast cancer based on hormone receptor status
    Aditya Bardia
    Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Arch Intern Med 166:2478-83. 2006
    ..The objective of this study was to examine the association of physical activity with breast cancer incidence based on ER/PR status of the tumor...
  37. ncbi Vegetables, fruit, and antioxidant-related nutrients and risk of non-Hodgkin lymphoma: a National Cancer Institute-Surveillance, Epidemiology, and End Results population-based case-control study
    Linda E Kelemen
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Am J Clin Nutr 83:1401-10. 2006
    ..Factors related to DNA damage and altered immunologic responses, such as reactive oxygen species production, are associated with the risk of non-Hodgkin lymphoma (NHL)...
  38. pmc Texture features from mammographic images and risk of breast cancer
    Armando Manduca
    Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 1st Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 18:837-45. 2009
    ..However, simultaneous inclusion of these features in a model with PD did not significantly improve the ability to predict breast cancer...
  39. ncbi Cigarette smoking and colorectal cancer: long-term, subsite-specific risks in a cohort study of postmenopausal women
    Paul J Limburg
    Divisions of Gastroenterology and Hepatology and Epidemiology, Mayo Clinic Cancer Center, Rochester, Minnesota, USA
    Clin Gastroenterol Hepatol 1:202-10. 2003
    ..However, long-term CRC risk estimates among female smokers remain limited and inconsistent. The goal of this prospective study was to assess cigarette smoking and CRC risk, overall and by anatomic subsite, among postmenopausal women...
  40. ncbi Evaluation of familial clustering of breast and prostate cancer in the Minnesota Breast Cancer Family Study
    Dawn M Grabrick
    Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Cancer Detect Prev 27:30-6. 2003
    ..8, 95% C.I.: 0.5-1.2). These results provide little evidence that male relatives in high-risk breast cancer families are at increased risk of prostate cancer...
  41. ncbi High expression levels of insulin-like growth factor-I receptor predict poor survival among women with clear-cell renal cell carcinomas
    Alexander S Parker
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Hum Pathol 33:801-5. 2002
    ....
  42. ncbi Association of correlates of endogenous hormonal exposure with breast cancer risk in 426 families (United States)
    Dawn M Grabrick
    Mayo Clinic, Department of Health Sciences Research, Rochester, Minnesota 55905, USA
    Cancer Causes Control 13:333-41. 2002
    ..We examined whether a family history of breast cancer modifies the association between correlates of endogenous hormonal exposures and breast cancer in a study of 426 families ascertained through breast cancer probands...
  43. pmc Association of genetic variation in genes implicated in the beta-catenin destruction complex with risk of breast cancer
    Xianshu Wang
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Stabile 2 42, 200 First Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 17:2101-8. 2008
    ....
  44. ncbi High-folate diets and breast cancer survival in a prospective cohort study
    Thomas A Sellers
    Department of Health Sciences Research, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, MN 55905, USA
    Nutr Cancer 44:139-44. 2002
    ..These findings, although preliminary, afford some reassurance that folate supplementation is unlikely to have a significant adverse effect on survival after chemotherapy for breast cancer...
  45. pmc Polymorphisms in mitochondrial genes and prostate cancer risk
    Liang Wang
    Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 17:3558-66. 2008
    ..Overall, these results suggest that polymorphisms in the mitochondrial genome and those in the nuclear-encoded mitochondrial genes evaluated are not substantial risk factors for prostate cancer...
  46. pmc Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era
    Thomas M Habermann
    Mayo Clinic College of Medicine, Rochester, MN, USA
    Blood 112:2694-702. 2008
    ..These data support a role for germ line variation in immune genes, particularly genes associated with a proinflammatory state, as predictors of late survival in DLBCL...
  47. ncbi Role of the Nijmegen breakage syndrome 1 gene in familial and sporadic prostate cancer
    Scott J Hebbring
    Mayo Clinic Rochester, 200 First Street Southwest, 920 Hilton Building, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 15:935-8. 2006
    ..However, our data does suggest that mutations within NBS1, and in particular, 657del5, do not significantly contribute to the overall prostate cancer burden within our patient samples...
  48. pmc Factors associated with breast cancer prevention communication between mothers and daughters
    Pamela S Sinicrope
    Behavioral Health Program, Mayo Clinic Rochester College of Medicine, Rochester, Minnesota 55905, USA
    J Womens Health (Larchmt) 17:1017-23. 2008
    ..We examined the degree to which mothers reported providing advice on breast cancer prevention to their daughters, the content of such advice, and correlates of providing such advice...
  49. ncbi History of urinary tract infection and risk of renal cell carcinoma
    Alexander S Parker
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Am J Epidemiol 159:42-8. 2004
    ..Results suggest a positive association of UTI history with RCC development, with elevated risks most notable for males with a history of smoking...
  50. ncbi Microarray and microfluidic methodology for genotyping cytokine gene polymorphisms
    Youvraj R Sohni
    Mayo Clinic Cancer Center Microarray Shared Resource, Rochester, MN 55905, USA
    Hum Immunol 64:990-7. 2003
    ..Comprehensive genotyping can be achieved for clinical epidemiologic studies on cytokine gene polymorphisms using this approach...
  51. pmc Prospective evaluation of trans-fatty acid intake and colorectal cancer risk in the Iowa Women's Health Study
    Paul J Limburg
    Mayo Clinic Cancer Center, Rochester, MN 55905, USA
    Int J Cancer 123:2717-9. 2008
    ..Multivariable adjustment yielded slightly attenuated risk estimates, but the observed associations were not meaningfully altered. Given these findings, tFA intake does not appear to be a major CRC risk factor, at least among older women...
  52. ncbi Smoking cessation and renal cell carcinoma
    Alexander S Parker
    Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Ann Epidemiol 13:245-51. 2003
    ..Furthermore, conclusions from previous investigations have been hampered by unstable risk estimates, broad exposure categories and/or insufficient adjustment for the inverse correlation of cessation years with lifetime smoking exposure...
  53. ncbi Susceptibility genes and B-chronic lymphocytic leukaemia
    Susan L Slager
    Division of Biostatistics, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, USA
    Br J Haematol 139:762-71. 2007
    ..The challenge of future studies of this type will be overcoming study design issues, including definition of CLL, sample size limitations and multiple testing issues...
  54. pmc Association of genetic variation in mitotic kinases with breast cancer risk
    Xianshu Wang
    Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Breast Cancer Res Treat 119:453-62. 2010
    ..006) genes. Although requiring replication, these findings suggest that genetic polymorphisms in mitotic kinases that have been implicated in chromosome instability and aneuploidy may contribute to the development of breast cancer...
  55. pmc Genome-wide transcriptional profiling reveals microRNA-correlated genes and biological processes in human lymphoblastoid cell lines
    Liang Wang
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    PLoS ONE 4:e5878. 2009
    ..However, past studies have focused on the miRNA target genes and used loss- or gain-of-function approach that may not reflect natural association between miRNA and mRNAs...
  56. ncbi Interaction of waist/hip ratio and family history on the risk of hormone receptor-defined breast cancer in a prospective study of postmenopausal women
    Thomas A Sellers
    Department of Health Sciences Research, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, MN 55905, USA
    Am J Epidemiol 155:225-33. 2002
    ..9, 5.8). Thus, the previously reported interaction between family history and waist/hip ratio is still (weakly) evident and appears to reflect risk for progesterone receptor-negative tumors...
  57. ncbi Gender, alcohol consumption, and renal cell carcinoma
    Alexander S Parker
    Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Epidemiol 155:455-62. 2002
    ..These findings suggest an inverse association of alcohol consumption and RCC development among women but not among men...
  58. pmc Elevated serum free light chains are associated with event-free and overall survival in two independent cohorts of patients with diffuse large B-cell lymphoma
    Matthew J Maurer
    Mayo Clinic College of Medicine and Mayo Foundation, Rochester, MN 55905, USA
    J Clin Oncol 29:1620-6. 2011
    ..This assay has prognostic value in plasma cell proliferative disorders. There are limited data on serum FLC in B-cell malignancies...
  59. pmc Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL
    Susan L Slager
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Blood 117:1911-6. 2011
    ..Our findings support the hypothesis that familial CLL cases have additional genetic variants not seen in sporadic CLL. Additional loci among familial CLL cases may be identified through larger studies...
  60. pmc Smoking, alcohol use, obesity, and overall survival from non-Hodgkin lymphoma: a population-based study
    Susan M Geyer
    Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Cancer 116:2993-3000. 2010
    ..Smoking, alcohol use, and obesity appear to increase the risk of developing non-Hodgkin lymphoma (NHL), but to the authors' knowledge, few studies to date have assessed their impact on NHL prognosis...
  61. pmc Genetic susceptibility variants for chronic lymphocytic leukemia
    Susan L Slager
    Mayo Clinic College of Medicine, 200 1st Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 19:1098-102. 2010
    ..A recent genome-wide association study of CLL identified seven genetic variants that increased the risk of CLL within a European population...
  62. pmc Statin use and prognosis in patients with diffuse large B-cell lymphoma and follicular lymphoma in the rituximab era
    Grzegorz S Nowakowski
    Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 28:412-7. 2010
    ..The clinical impact of statin use on the outcome of lymphoma patients treated with a rituximab-containing regimen is unknown...
  63. pmc Gene networks and microRNAs implicated in aggressive prostate cancer
    Liang Wang
    Department of Laboratory Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Cancer Res 69:9490-7. 2009
    ....
  64. ncbi Interaction of dietary folate intake, alcohol, and risk of hormone receptor-defined breast cancer in a prospective study of postmenopausal women
    Thomas A Sellers
    Department of Health Sciences Research, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, Minnesota 55905, USA
    Cancer Epidemiol Biomarkers Prev 11:1104-7. 2002
    ....
  65. ncbi Association of parity and ovarian cancer risk by family history of breast or ovarian cancer in a population-based study of postmenopausal women
    Celine M Vachon
    Department of Health Sciences Research, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    Epidemiology 13:66-71. 2002
    ..Nulliparity may be more strongly associated with an increased risk of ovarian cancer among women with a family history of breast or ovarian cancer, compared with women who do not have a family history of those cancers...
  66. pmc The association of alcohol consumption with coronary heart disease mortality and cancer incidence varies by smoking history
    Jon O Ebbert
    Nicotine Research Center, Division of Community Internal Medicine, Rochester, MN 55905, USA
    J Gen Intern Med 20:14-20. 2005
    ..To evaluate the effect of alcohol on coronary heart disease (CHD), cancer incidence, and cancer mortality by smoking history...
  67. ncbi Associations of dietary protein with disease and mortality in a prospective study of postmenopausal women
    Linda E Kelemen
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Am J Epidemiol 161:239-49. 2005
    ..07, 1.86) when substituted for servings per 1,000 kcal (4.2 MJ) of carbohydrate foods. Long-term adherence to high-protein diets, without discrimination toward protein source, may have potentially adverse health consequences...
  68. ncbi Association of folate and alcohol with risk of ovarian cancer in a prospective study of postmenopausal women
    Linda E Kelemen
    Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Cancer Causes Control 15:1085-93. 2004
    ..These findings suggest that alcohol consumption is inversely related to postmenopausal ovarian cancer, and that the association of folate with ovarian cancer may vary by the amount of alcohol consumed...
  69. pmc Polyunsaturated fatty acids and reduced odds of MCI: the Mayo Clinic Study of Aging
    Rosebud O Roberts
    Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    J Alzheimers Dis 21:853-65. 2010
    ..In this study, higher intake of PUFA and MUFA was associated with a reduced likelihood of MCI among elderly persons in the population-based setting...
  70. ncbi Alcohol intake in adolescence and mammographic density
    Celine M Vachon
    Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Int J Cancer 117:837-41. 2005
    ..0-23.4%). However, these associations were not statistically significant (p = 0.27 and p = 0.22, respectively). In summary, there was no evidence that adolescent alcohol use was associated with large and persistent effects on adult PD...
  71. pmc Insulin, glucose, insulin resistance, and incident colorectal cancer in male smokers
    Paul J Limburg
    Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Clin Gastroenterol Hepatol 4:1514-21. 2006
    ..To date, few studies have directly examined serum insulin as an indicator of CRC risk, and none have reported associations on the basis of HOMA-IR...
  72. ncbi Oral contraceptive use and risk of breast cancer
    Petra M Casey
    Department of Obstetrics and Gynecology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Mayo Clin Proc 83:86-90; quiz 90-1. 2008
    ..We also have a better understanding of how estrogen affects breast carcinogenesis; research on this topic is ongoing and has the goal of decreasing breast cancer incidence and mortality...
  73. ncbi Pathologic T1 clear cell renal cell carcinoma: insulin-like growth factor-I receptor expression and disease-specific survival
    Alexander S Parker
    Department of Urology, Mayo College of Medicine, Jacksonville, Florida 32224, USA
    Cancer 100:2577-82. 2004
    ..The authors conducted a case-cohort investigation to examine the association of insulin-like growth factor I receptor (IGF-IR) expression and disease-specific survival in patients who underwent surgery for pT1 CC-RCC...
  74. pmc Relative weight at age 12 and risk of postmenopausal breast cancer
    Aditya Bardia
    Department of Internal Medicine, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, MN 55905, USA
    Cancer Epidemiol Biomarkers Prev 17:374-8. 2008
    ....
  75. ncbi Prepregnancy exposure to cigarette smoking and subsequent risk of postmenopausal breast cancer
    Janet E Olson
    Division of Epidemiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 80:1423-8. 2005
    ..To examine the association of cigarette smoking before first pregnancy with risk of postmenopausal breast cancer in a large population-based cohort...
  76. pmc Body size and incident colorectal cancer: a prospective study of older women
    Amy S Oxentenko
    College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Cancer Prev Res (Phila) 3:1608-20. 2010
    ..e., early adulthood versus later adulthood) might also be informative, particularly with respect to defining subsite-specific pathways of colorectal carcinogenesis...
  77. pmc Risk factors for meningioma in postmenopausal women: results from the Iowa Women's Health Study
    Derek R Johnson
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Neuro Oncol 13:1011-9. 2011
    ..The positive association with height suggests a role for early life influences on risk, whereas the associations with BMI and physical activity suggest a role for modifiable factors later in life...
  78. ncbi Cigarette smoking and the risk of rheumatoid arthritis among postmenopausal women: results from the Iowa Women's Health Study
    Lindsey A Criswell
    Rosalind Russell Medical Research Center for Arthritis LAC, University of California, San Francisco, USA
    Am J Med 112:465-71. 2002
    ..To determine whether cigarette smoking increases the risk of rheumatoid arthritis among postmenopausal women...
  79. ncbi Risk of non-Hodgkin lymphoma and nitrate and nitrite from drinking water and diet
    Mary H Ward
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, Bethesda, MD 20892, USA
    Epidemiology 17:375-82. 2006
    ..Nitrate and nitrite are precursors in the in vivo formation of N-nitroso compounds, potent animal carcinogens...
  80. ncbi Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph Consortium
    Nathaniel Rothman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Lancet Oncol 7:27-38. 2006
    ..We aimed to test this hypothesis using previously unpublished data from eight European, Canadian, and US case-control studies of the International Lymphoma Epidemiology Consortium (InterLymph)...
  81. pmc Asthma history, occupational exposure to pesticides and the risk of non-Hodgkin's lymphoma
    Won Jin Lee
    Department of Preventive Medicine, College of Medicine, Korea University, Seoul
    Int J Cancer 118:3174-6. 2006
    ..2-29.0) or daily medication for asthma (OR = infinite) than those among asthmatics who did not have such histories. Our results support the previous finding that the risk of NHL from pesticide exposure may be greater among asthmatics...
  82. ncbi Hormone replacement therapy is not associated with an increased risk of leukemia (United States)
    Julie A Ross
    Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    Cancer Causes Control 16:483-8. 2005
    ..Since estrogen receptors are expressed on certain hematopoietic cells, it is possible that HRT use may also increase the risk of leukemia...
  83. ncbi Anthropometric characteristics and risk of multiple myeloma
    Cindy K Blair
    Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA
    Epidemiology 16:691-4. 2005
    ..Few studies have examined obesity and risk for multiple myeloma, and the results are inconsistent. Laboratory evidence suggests mechanisms through which obesity could influence carcinogenesis of this hematopoietic malignancy...
  84. pmc Dietary flavonoid intake and non-Hodgkin lymphoma risk
    Cara L Frankenfeld
    Division of Cancer, Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
    Am J Clin Nutr 87:1439-45. 2008
    ..Dietary flavonoids are polyphenolic compounds proposed to be anticarcinogenic. Flavonoids are well-characterized antioxidants and metal chelators, and certain flavonoids exhibit antiproliferative and antiestrogenic effects...
  85. ncbi Polymorphisms in oxidative stress genes and risk for non-Hodgkin lymphoma
    Sophia S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA
    Carcinogenesis 27:1828-34. 2006
    ....
  86. ncbi Dietary carotenoids and risk of lung cancer in a pooled analysis of seven cohort studies
    Satu Mannisto
    Harvard School of Public Health, Department of Nutrition, Boston, Massachusetts, USA
    Cancer Epidemiol Biomarkers Prev 13:40-8. 2004
    ..Although smoking is the strongest risk factor for lung cancer, greater intake of foods high in beta-cryptoxanthin, such as citrus fruit, may modestly lower the risk...
  87. ncbi Sun exposure, vitamin D receptor gene polymorphisms and risk of non-Hodgkin lymphoma
    Mark P Purdue
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 8009, Rockville, MD 20892, USA
    Cancer Causes Control 18:989-99. 2007
    ....
  88. ncbi Risk of non-Hodgkin's lymphoma and family history of lymphatic, hematologic, and other cancers
    Nilanjan Chatterjee
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 13:1415-21. 2004
    ..An elevated risk of developing non-Hodgkin's lymphoma (NHL) has been associated with a family history of NHL and several other malignancies, but the magnitude of risks and mechanisms are uncertain...
  89. pmc Family history of hematopoietic malignancies and risk of non-Hodgkin lymphoma (NHL): a pooled analysis of 10 211 cases and 11 905 controls from the International Lymphoma Epidemiology Consortium (InterLymph)
    Sophia S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Blood 109:3479-88. 2007
    ..0; 95% CI = 1.6-5.6). The pattern of NHL heritability appeared to be uniform across NHL subtypes, but risk patterns differed by specific hematopoietic malignancies and the sex of the relative, revealing critical clues to disease etiology...
  90. ncbi Meat and meat-mutagen intake and risk of non-Hodgkin lymphoma: results from a NCI-SEER case-control study
    Amanda J Cross
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20892, USA
    Carcinogenesis 27:293-7. 2006
    ..39 (0.22-0.70); P trend = 0.004]. Overall, our study suggests that consumption of meat, whether or not it is well-done, does not increase the risk of NHL. Furthermore, neither HCAs nor B[a]P from meat increase the risk of NHL...
  91. ncbi Association of gain and loss of weight before and after menopause with risk of postmenopausal breast cancer in the Iowa women's health study
    Michelle Harvie
    Univeristy Department of Medical Oncology, Christie Hospital, Manchester, United Kingdom
    Cancer Epidemiol Biomarkers Prev 14:656-61. 2005
    ..These data suggest prevention of weight gain between age 18 years and menopause or weight loss and maintenance during these years reduces risk of postmenopausal breast cancer...
  92. ncbi Dietary carotenoids and risk of colorectal cancer in a pooled analysis of 11 cohort studies
    Satu Mannisto
    National Public Health Institute, Helsinki, Finland
    Am J Epidemiol 165:246-55. 2007
    ..00). The associations observed were generally similar across studies, for both sexes, and for colon cancer and rectal cancer. These pooled data did not suggest that carotenoids play an important role in the etiology of colorectal cancer...
  93. ncbi No association between 25-hydroxyvitamin D and mammographic density
    Julia A Knight
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 5th Floor, 60 Murray Street, Toronto, Ontario, Canada M5G 1X5
    Cancer Epidemiol Biomarkers Prev 15:1988-92. 2006
    ..Unlike some previous reports, vitamin D does not seem to be related to mammographic density in this cohort...
  94. ncbi Common genetic variants in proinflammatory and other immunoregulatory genes and risk for non-Hodgkin lymphoma
    Sophia S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20892 7234, USA
    Cancer Res 66:9771-80. 2006
    ..Our results require replication but potentially provide important clues for investigating common genetic variants as susceptibility factors and in disease outcomes, treatment responses, and immunotherapy targets...
  95. ncbi GSTM1 and GSTT1 polymorphisms and postmenopausal breast cancer risk
    Wei Zheng
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA
    Breast Cancer Res Treat 74:9-16. 2002
    ..3, 95% CI = 0.4-4.1). This study suggests that certain null GST genotypes may be associated with an elevated risk of breast cancer and the association may be modified by charred meat intake and cigarette smoking...

Research Grants16

  1. Immunogenetics of Non-Hodgkin Lymphoma Survival
    James Cerhan; Fiscal Year: 2002
    ..abstract_text> ..
  2. Molecular Epidemiology of NHL and CLL
    James R Cerhan; Fiscal Year: 2010
    ....
  3. Molecular Epidemiology of non-Hodgkin Lymphoma Survival
    James R Cerhan; Fiscal Year: 2010
    ..Host genetics may also lead to a better understanding of NHL pathophysiology that could lead to new approaches to improve the survival of NHL patients. ..
  4. Molecular Epidemiology of NHL and CLL
    James Cerhan; Fiscal Year: 2009
    ....
  5. Molecular Epidemiology of non-Hodgkin Lymphoma Survival
    James Cerhan; Fiscal Year: 2009
    ..Host genetics may also lead to a better understanding of NHL pathophysiology that could lead to new approaches to improve the survival of NHL patients. ..
  6. Molecular Epidemiology of NHL and CLL
    James Cerhan; Fiscal Year: 2007
    ..In summary, we will evaluate critical hypotheses regarding environmental and genetic risk factors for NHL and CLL, and should greatly contribute to our understanding the causes and possible prevention of these cancers. ..
  7. Immunogenetics of Non-Hodgkin Lymphoma Survival
    James Cerhan; Fiscal Year: 2006
    ..abstract_text> ..
  8. Molecular Epidemiology of NHL and CLL
    James Cerhan; Fiscal Year: 2006
    ..In summary, we will evaluate critical hypotheses regarding environmental and genetic risk factors for NHL and CLL, and should greatly contribute to our understanding the causes and possible prevention of these cancers. ..
  9. Immunogenetics of Non-Hodgkin Lymphoma Survival
    James Cerhan; Fiscal Year: 2005
    ..abstract_text> ..
  10. Molecular Epidemiology of NHL and CLL
    James Cerhan; Fiscal Year: 2005
    ..In summary, we will evaluate critical hypotheses regarding environmental and genetic risk factors for NHL and CLL, and should greatly contribute to our understanding the causes and possible prevention of these cancers. ..
  11. Immunogenetics of Non-Hodgkin Lymphoma Survival
    James Cerhan; Fiscal Year: 2004
    ..abstract_text> ..
  12. Molecular Epidemiology of NHL and CLL
    James Cerhan; Fiscal Year: 2004
    ..In summary, we will evaluate critical hypotheses regarding environmental and genetic risk factors for NHL and CLL, and should greatly contribute to our understanding the causes and possible prevention of these cancers. ..
  13. Immunogenetics of Non-Hodgkin Lymphoma Survival
    James Cerhan; Fiscal Year: 2003
    ..abstract_text> ..
  14. Molecular Epidemiology of NHL and CLL
    James Cerhan; Fiscal Year: 2003
    ..In summary, we will evaluate critical hypotheses regarding environmental and genetic risk factors for NHL and CLL, and should greatly contribute to our understanding the causes and possible prevention of these cancers. ..
  15. Molecular Epidemiology of NHL and CLL
    James Cerhan; Fiscal Year: 2009
    ....