J A Carney


Affiliation: Mayo Clinic
Country: USA


  1. Carney J, Stratakis C. Stromal, fibrous, and fatty gastrointestinal tumors in a patient with a PDGFRA gene mutation. Am J Surg Pathol. 2008;32:1412-20 pubmed publisher
    ..The patient is currently asymptomatic; radiologic study in June 2007 revealed postoperative changes only. None of the patient's primary relatives have had similar tumors. ..
  2. Carney J, Young W, Stratakis C. Primary bimorphic adrenocortical disease: cause of hypercortisolism in McCune-Albright syndrome. Am J Surg Pathol. 2011;35:1311-26 pubmed publisher
    ..The findings are different from those in inherited or other forms of genetically caused Cushing syndrome. The ninth patient, aged 17 years, had an adrenal adenoma and diffuse cortical hyperplasia in each adrenal gland. ..
  3. Carney J, Stratakis C. Virilizing ovarian stromal tumor in a young woman with Carney complex. Am J Surg Pathol. 2011;35:1592-9 pubmed publisher
    ..Immunocytochemically, the tumor cells were positive for vimentin, synaptophysin, inhibin-A, and calrenin. Because of the clinical setting in which the neoplasm occurred, it is likely that is occurrence was related to Carney complex. ..
  4. Carney J, Ho J, Kitsuda K, Young W, Stratakis C. Massive neonatal adrenal enlargement due to cytomegaly, persistence of the transient cortex, and hyperplasia of the permanent cortex: findings in Cushing syndrome associated with hemihypertrophy. Am J Surg Pathol. 2012;36:1452-63 pubmed publisher
    ..The pathologic findings were most likely the result of the genetic mutation identified in 1 patient and of an unknown mutation in the remaining 2 patients. ..
  5. Carney J, Stratakis C, Young W. Adrenal cortical adenoma: the fourth component of the Carney triad and an association with subclinical Cushing syndrome. Am J Surg Pathol. 2013;37:1140-9 pubmed publisher
    ..None of the tumors recurred or metastasized. Fourteen additional patients had unilateral or bilateral adrenal tumors consistent with adenomas detected by imaging studies. ..
  6. Carney J, Lyssikatos C, Lodish M, Stratakis C. Germline PRKACA amplification leads to Cushing syndrome caused by 3 adrenocortical pathologic phenotypes. Hum Pathol. 2015;46:40-9 pubmed publisher
    ..Catenin stained the cell membrane, cytoplasm, and nuclei of the adenoma. The patients were well at follow-up (1-23 years); 24-hour urinary cortisol excretion was elevated in the patient who had unilateral adrenalectomy. ..
  7. Carney J, Gaillard R, Bertherat J, Stratakis C. Familial micronodular adrenocortical disease, Cushing syndrome, and mutations of the gene encoding phosphodiesterase 11A4 (PDE11A). Am J Surg Pathol. 2010;34:547-55 pubmed publisher
    ..In the remaining patient, the glands were slightly enlarged primarily owing to a diffuse hyperplasia of the superficial cortex that extended into the epi-adrenal fat. ..
  8. Carney J. Hyalinizing trabecular tumors of the thyroid gland: quadruply described but not by the discoverer. Am J Surg Pathol. 2008;32:622-34 pubmed publisher
    ..Hyalinizing trabecular carcinoma is a very rare tumor. ..
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    Carney J. Familial multiple endocrine neoplasia syndromes: components, classification, and nomenclature. J Intern Med. 1998;243:425-32 pubmed
    ..To regard these conditions as MEN syndromes would require an inappropriate demotion of their predominant nonendocrine manifestations. The role of nonendocrine disorders in MEN syndromes needs reappraisal...

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    Carney J. Familial multiple endocrine neoplasia: the first 100 years. Am J Surg Pathol. 2005;29:254-74 pubmed
  2. Carney J. Carney triad: a syndrome featuring paraganglionic, adrenocortical, and possibly other endocrine tumors. J Clin Endocrinol Metab. 2009;94:3656-62 pubmed publisher
    ..Two young women, each with paraganglioma and gastric stromal tumor, were encountered in the middle 1970s. One also had an adrenal cortical adenoma and the other pulmonary chondroma...