J A Carney

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. pmc Adrenal cortical adenoma: the fourth component of the Carney triad and an association with subclinical Cushing syndrome
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Am J Surg Pathol 37:1140-9. 2013
  2. doi request reprint Carney triad
    J Aidan Carney
    Department of Laboratory Medicine and Pathology and College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Front Horm Res 41:92-110. 2013
  3. pmc Massive neonatal adrenal enlargement due to cytomegaly, persistence of the transient cortex, and hyperplasia of the permanent cortex: findings in Cushing syndrome associated with hemihypertrophy
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 36:1452-63. 2012
  4. doi request reprint Carney triad: a syndrome featuring paraganglionic, adrenocortical, and possibly other endocrine tumors
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Clin Endocrinol Metab 94:3656-62. 2009
  5. doi request reprint Hyalinizing trabecular tumors of the thyroid gland are almost all benign
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 32:1877-89. 2008
  6. ncbi request reprint Familial multiple endocrine neoplasia: the first 100 years
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 29:254-74. 2005
  7. doi request reprint Hyalinizing trabecular tumors of the thyroid gland: quadruply described but not by the discoverer
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 32:622-34. 2008
  8. doi request reprint Gastric mucosal lymphoid follicles: histology, distribution, frequency, and etiologic features
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Surg Pathol 34:1019-24. 2010
  9. doi request reprint Primary bimorphic adrenocortical disease: cause of hypercortisolism in McCune-Albright syndrome
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Division of Endocrinology, Diabetes, Nutrition and Metabolism, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Surg Pathol 35:1311-26. 2011
  10. pmc Virilizing ovarian stromal tumor in a young woman with Carney complex
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Am J Surg Pathol 35:1592-9. 2011

Detail Information

Publications51

  1. pmc Adrenal cortical adenoma: the fourth component of the Carney triad and an association with subclinical Cushing syndrome
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Am J Surg Pathol 37:1140-9. 2013
    ..None of the tumors recurred or metastasized. Fourteen additional patients had unilateral or bilateral adrenal tumors consistent with adenomas detected by imaging studies. ..
  2. doi request reprint Carney triad
    J Aidan Carney
    Department of Laboratory Medicine and Pathology and College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Front Horm Res 41:92-110. 2013
    ..Among the 79 affected patients described in 1999 (average follow-up 8 years, 64 were alive, 19 were apparently free of tumors, 45 had residual or metastatic disease, and 15 were dead (10 died of causes related to the syndrome)...
  3. pmc Massive neonatal adrenal enlargement due to cytomegaly, persistence of the transient cortex, and hyperplasia of the permanent cortex: findings in Cushing syndrome associated with hemihypertrophy
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 36:1452-63. 2012
    ..The pathologic findings were most likely the result of the genetic mutation identified in 1 patient and of an unknown mutation in the remaining 2 patients...
  4. doi request reprint Carney triad: a syndrome featuring paraganglionic, adrenocortical, and possibly other endocrine tumors
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Clin Endocrinol Metab 94:3656-62. 2009
    ..Two young women, each with paraganglioma and gastric stromal tumor, were encountered in the middle 1970s. One also had an adrenal cortical adenoma and the other pulmonary chondroma...
  5. doi request reprint Hyalinizing trabecular tumors of the thyroid gland are almost all benign
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 32:1877-89. 2008
    ..We conclude that the overwhelming majority of hyalinizing trabecular tumors of the thyroid behave as benign neoplasms and that, at this time, hyalinizing trabecular adenoma is the most appropriate title for them...
  6. ncbi request reprint Familial multiple endocrine neoplasia: the first 100 years
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 29:254-74. 2005
    ....
  7. doi request reprint Hyalinizing trabecular tumors of the thyroid gland: quadruply described but not by the discoverer
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 32:622-34. 2008
    ..Hyalinizing trabecular carcinoma is a very rare tumor...
  8. doi request reprint Gastric mucosal lymphoid follicles: histology, distribution, frequency, and etiologic features
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Surg Pathol 34:1019-24. 2010
    ..The follicles were most frequent in the patients with multiple stromal sarcomas (1 follicle/8 mm of mucosa) and least frequent in pediatric patients...
  9. doi request reprint Primary bimorphic adrenocortical disease: cause of hypercortisolism in McCune-Albright syndrome
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Division of Endocrinology, Diabetes, Nutrition and Metabolism, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Surg Pathol 35:1311-26. 2011
    ..The findings are different from those in inherited or other forms of genetically caused Cushing syndrome. The ninth patient, aged 17 years, had an adrenal adenoma and diffuse cortical hyperplasia in each adrenal gland...
  10. pmc Virilizing ovarian stromal tumor in a young woman with Carney complex
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Am J Surg Pathol 35:1592-9. 2011
    ..Immunocytochemically, the tumor cells were positive for vimentin, synaptophysin, inhibin-A, and calrenin. Because of the clinical setting in which the neoplasm occurred, it is likely that is occurrence was related to Carney complex...
  11. doi request reprint Familial micronodular adrenocortical disease, Cushing syndrome, and mutations of the gene encoding phosphodiesterase 11A4 (PDE11A)
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Surg Pathol 34:547-55. 2010
    ..In the remaining patient, the glands were slightly enlarged primarily owing to a diffuse hyperplasia of the superficial cortex that extended into the epi-adrenal fat...
  12. ncbi request reprint Familial paraganglioma and gastric stromal sarcoma: a new syndrome distinct from the Carney triad
    J Aidan Carney
    Department of Laboratory Medicine and Pathology Emeritus member, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Am J Med Genet 108:132-9. 2002
    ....
  13. ncbi request reprint Familial multiple endocrine neoplasia syndromes: components, classification, and nomenclature
    J A Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Intern Med 243:425-32. 1998
    ..To regard these conditions as MEN syndromes would require an inappropriate demotion of their predominant nonendocrine manifestations. The role of nonendocrine disorders in MEN syndromes needs reappraisal...
  14. pmc Stromal, fibrous, and fatty gastrointestinal tumors in a patient with a PDGFRA gene mutation
    J Aidan Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 32:1412-20. 2008
    ..The patient is currently asymptomatic; radiologic study in June 2007 revealed postoperative changes only. None of the patient's primary relatives have had similar tumors...
  15. ncbi request reprint Prevalence and incidence of cytoplasmic yellow bodies in thyroid neoplasms
    Harold J Rothenberg
    Division of Anatomic Pathology, Mayo Clinic, Rochester, Minn 55905, USA
    Arch Pathol Lab Med 127:715-7. 2003
    ..Cytoplasmic yellow bodies are a common and frequent histologic finding in hyalinizing trabecular adenoma of the thyroid gland, a morphologically distinctive neoplasm, and are visible in fine-needle aspiration biopsy of the tumor...
  16. ncbi request reprint Association of Peutz-Jeghers-like mucocutaneous pigmentation with breast and gynecologic carcinomas in women
    L A Boardman
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Medicine (Baltimore) 79:293-8. 2000
    ..In particular, the relative risk for cancer in females with IMMP was significantly increased, as is true in females with PJS. However, LKB1 mutations did not contribute to the development of IMMP in the patients tested...
  17. ncbi request reprint An immunophenotypic comparison of metanephric metaplasia of Bowman capsular epithelium with metanephric adenoma, Wilms tumor, and renal development: a case report and review of the literature
    Edgar G Fischer
    Department of Laboratory Medicine, Mayo Foundation, Rochester, MN 55905, USA
    Am J Clin Pathol 121:850-6. 2004
    ..This immunophenotype parallels that of metanephric adenoma, Wilms tumor, and nephrogenic rests and overlaps with antigen expression in certain periods of renal development...
  18. ncbi request reprint Hyalinizing trabecular adenoma of the thyroid gland: cytologic features in 29 cases
    Mary B Casey
    Department of Pathology and Laboratory Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 28:859-67. 2004
    ....
  19. ncbi request reprint The clinical conundrum of corticotropin-independent autonomous cortisol secretion in patients with bilateral adrenal masses
    William F Young
    Division of Endocrinology, Department of Radiology, Mayo Clinic Rochester, 200 First Street SW, Rochester, Minnesota 55905, USA
    World J Surg 32:856-62. 2008
    ..We report our experience with adrenal venous sampling (AVS) in the evaluation of 10 patients with bilateral masses who had ACTH-independent CS or subclinical CS...
  20. ncbi request reprint Achlorhydria, parietal cell hyperplasia, and multiple gastric carcinoids: a new disorder
    Susan C Abraham
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 29:969-75. 2005
    ....
  21. ncbi request reprint Epithelioid gastric stromal tumors (leiomyoblastomas): a study of fifty-five cases
    J S Lee
    Division of Gastroenterologic and General Surgery, Mayo Clinic, Rochester, MN 55905, USA
    Surgery 118:653-60; discussion 660-1. 1995
    ..01). Proximal lesions were more likely to be malignant. Extent of surgical treatment had no effect on survival...
  22. ncbi request reprint Pulmonary chondroma: a tumor associated with Carney triad and different from pulmonary hamartoma
    Fausto J Rodriguez
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 31:1844-53. 2007
    ..They differ pathologically from pulmonary cartilaginous hamartomas on the basis of the presence of a thin fibrous pseudocapsule, frequent bone metaplasia, and calcification, and also the absence of entrapped epithelium and fat...
  23. ncbi request reprint Hyalinizing trabecular adenoma of the thyroid gland identification through MIB-1 staining of fine-needle aspiration biopsy smears
    Mary B Casey
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Clin Pathol 122:506-10. 2004
    ..Hyalinizing trabecular adenoma can be distinguished reliably from other thyroid neoplasms by MIB-1 staining of destained cells from FNA biopsy specimens...
  24. ncbi request reprint Osteochondromyxoma of bone: a congenital tumor associated with lentigines and other unusual disorders
    J A Carney
    Department of Laboratory Medicine and Pathology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Am J Surg Pathol 25:164-76. 2001
    ..No tumor metastasized...
  25. ncbi request reprint Functioning paraganglioma and gastrointestinal stromal tumor of the jejunum in three women: syndrome or coincidence
    Colin G Perry
    Department of Medicine Endocrinology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Surg Pathol 30:42-9. 2006
    ..The paraganglioma-jejunal GIST combination may be the harbinger of a rare genetic syndrome, a variant of the Carney triad or the paraganglioma-gastric stromal sarcoma syndrome, or be coincidental...
  26. ncbi request reprint Pituitary adenoma in Carney complex: an immunohistochemical, ultrastructural, and immunoelectron microscopic study
    O Kurtkaya-Yapicier
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Ultrastruct Pathol 26:345-53. 2002
    ..The lack of morphologic similarity between the 2 adenomas indicatesthat pituitary tumors in patients with Carney complex may not exhibit the same phenotype...
  27. doi request reprint Surgery for Cushing's syndrome: an historical review and recent ten-year experience
    John R Porterfield
    Department of Surgery, Mayo Clinic and Mayo Foundation, 200 First Street, S W, Rochester, MN 55905, USA
    World J Surg 32:659-77. 2008
    ....
  28. ncbi request reprint Galectin-3 expression in hyalinizing trabecular tumors of the thyroid gland
    Robyn L Gaffney
    Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Surg Pathol 27:494-8. 2003
    ..Our study suggests that the variable pattern of galectin-3 expression may reflect a difference in biologic behavior between HTT and papillary thyroid carcinoma...
  29. ncbi request reprint RASSF1A and NORE1A methylation and BRAFV600E mutations in thyroid tumors
    Nobuki Nakamura
    Department of Laboratory Medicine and Pathology, Mayo Clinic Medical College, Rochester, MN 55905, USA
    Lab Invest 85:1065-75. 2005
    ..BRAF mutation occurs later in thyroid tumor progression and is restricted mainly to PTC and anaplastic thyroid carcinoma...
  30. pmc Gastric stromal tumors in Carney triad are different clinically, pathologically, and behaviorally from sporadic gastric gastrointestinal stromal tumors: findings in 104 cases
    Lizhi Zhang
    Department of Laboratory Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 34:53-64. 2010
    ..Thus, the Carney triad gastric stromal tumor is different clinically, pathologically, and behaviorally from sporadic gastric GIST...
  31. ncbi request reprint Thyroid gland: international case conference
    Kennichi Kakudo
    Deparmtent of Pathology, Wakayama Medical University, Kimiidera, Wakayama, Japan
    Endocr Pathol 13:131-4. 2002
    ..In this article, we present two of the cases, attempt to explain the reason for disagreement in their diagnoses, and propose what should be done to obtain better consensus in diagnosis...
  32. ncbi request reprint Cyclical Cushing syndrome presenting in infancy: an early form of primary pigmented nodular adrenocortical disease, or a new entity?
    Daniel F Gunther
    Section on Endocrinology and Genetics, Developmental Endocrinology Branch, National Institute of Child Health and Human Development NIH, Building 10, Room 10N262, 10 Center Drive MSC 1862, Bethesda, MD 20892 1862, USA
    J Clin Endocrinol Metab 89:3173-82. 2004
    ....
  33. ncbi request reprint Multiple gastrointestinal stromal and other tumors caused by platelet-derived growth factor receptor alpha gene mutations: a case associated with a germline V561D defect
    Barbara Pasini
    Department of Genetics, Biology, and Biochemistry, University of Turin, Turin, Italy
    J Clin Endocrinol Metab 92:3728-32. 2007
    ....
  34. ncbi request reprint Genetics of carney triad: recurrent losses at chromosome 1 but lack of germline mutations in genes associated with paragangliomas and gastrointestinal stromal tumors
    Ludmila Matyakhina
    Section on Endocrinology and Genetics, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Clin Endocrinol Metab 92:2938-43. 2007
    ....
  35. ncbi request reprint A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia
    Anelia Horvath
    Section on Endocrinology and Genetics, Developmental Endocrinology Branch, US National Institute of Child Health and Human Development, US National Institutes of Health, Bethesda, Maryland 20892, USA
    Nat Genet 38:794-800. 2006
    ....
  36. ncbi request reprint An asymptomatic, incidentally discovered pulmonary tumor in a 41-year-old woman
    Rajmohan Murali
    Department of Tissue Pathology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales, Australia
    Arch Pathol Lab Med 129:e191-4. 2005
  37. ncbi request reprint A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues
    Lawrence S Kirschner
    Human Cancer Genetics Program, and Division of Endocrinology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio 43210, USA
    Cancer Res 65:4506-14. 2005
    ....
  38. pmc Molecular analysis of the cyclic AMP-dependent protein kinase A (PKA) regulatory subunit 1A (PRKAR1A) gene in patients with Carney complex and primary pigmented nodular adrenocortical disease (PPNAD) reveals novel mutations and clues for pathophysiology:
    Lionel Groussin
    Departments of Endocrinology, Institut Cochin, INSERM U576, CNRS UMR 8104 IFR116, René Descartes Paris V University, France
    Am J Hum Genet 71:1433-42. 2002
    ....
  39. ncbi request reprint Observer variation of encapsulated follicular lesions of the thyroid gland
    Mitsuyoshi Hirokawa
    Department of Pathology, University of Tokushima School of Medicine, Japan
    Am J Surg Pathol 26:1508-14. 2002
    ..To reduce observer variation of encapsulated follicular lesions, it will be necessary to provide more explicit criteria for diagnosis...
  40. ncbi request reprint Carney complex
    J Aidan Carney
    Am J Surg Pathol 26:393. 2002
  41. ncbi request reprint Cytokeratin profile and neuroendocrine cells in the glandular component of cardiac myxoma
    Angela Pucci
    Department of Pathology, Regina Margherita Hospital, Torino, Italy
    Virchows Arch 443:618-24. 2003
    ....
  42. ncbi request reprint Pigmented epithelioid melanocytoma: a low-grade melanocytic tumor with metastatic potential indistinguishable from animal-type melanoma and epithelioid blue nevus
    Artur Zembowicz
    Dermatopathology Unit, Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 28:31-40. 2004
    ..We suggest that PEM be considered as a provisional histologic entity encompassing both animal-type melanoma and epithelioid blue nevus...
  43. ncbi request reprint Carney triad: case report and molecular analysis of gastric tumor
    Judith Diment
    Department of Pathology, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy
    Hum Pathol 36:112-6. 2005
    ..The molecular analysis of the GIST, the first reported in a gastric tumor from the triad, showed a wild-type KIT and PDGFRA genes...
  44. ncbi request reprint A PRKAR1A mutation associated with primary pigmented nodular adrenocortical disease in 12 kindreds
    Lionel Groussin
    Institut National de la Santé et de la Recherche Médicale U 567, Centre National de la Recherche Scientifique Unite Mixte de Recherche 8104, Universite Rene Descartes, Paris 5, 75014 Paris, France
    J Clin Endocrinol Metab 91:1943-9. 2006
    ..Germline PRKAR1A-inactivating mutations have been observed in both CNC and iPPNAD, but with no apparent genotype-phenotype correlation...
  45. ncbi request reprint Adrenal hyperplasia and adenomas are associated with inhibition of phosphodiesterase 11A in carriers of PDE11A sequence variants that are frequent in the population
    Anelia Horvath
    Section on Endocrinology and Genetics, Developmental Endocrinology Branch, National Institute of Child Health and Human Resources, NIH, Bethesda, MD 20892, USA
    Cancer Res 66:11571-5. 2006
    ..We speculate that PDE11A genetic defects may be associated with adrenal pathology in a wider than previously suspected clinical spectrum that includes asymptomatic individuals...
  46. ncbi request reprint Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD
    Barbara Pasini
    Department of Genetics, Biology and Biochemistry, University of Torino, Turin, Italy
    Eur J Hum Genet 16:79-88. 2008
    ..We conclude that succinate dehydrogenase deficiency may be the cause of a subgroup of GISTs and this offers a therapeutic target for GISTs that may not respond to STI571 and its analogs...
  47. ncbi request reprint Mutation of perinatal myosin heavy chain
    Constantine A Stratakis
    N Engl J Med 351:2556-8; author reply 2556-8. 2004
  48. ncbi request reprint Hypodense nodularity on computed tomography: novel imaging and pathology of micronodular adrenocortical hyperplasia associated with myelolipomatous changes
    Nickolas A Courcoutsakis
    Department of Diagnostic Radiology, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892 1862, USA
    J Clin Endocrinol Metab 89:3737-8. 2004
  49. ncbi request reprint Molecular profile of hyalinizing trabecular tumours of the thyroid: high prevalence of RET/PTC rearrangements and absence of B-raf and N-ras point mutations
    Giuliana Salvatore
    Istituto di Endocrinologia ed Oncologia Sperimentale del CNR, c o Dipartimento di Biologia e Patologia Cellulare e Molecolare, University Federico II, Via S Pansini 5, 80131 Naples, Italy
    Eur J Cancer 41:816-21. 2005
    ..Thus, in clinical practice, the detection of B-raf mutations in a thyroid follicular tumour may prove to be a valuable tool, supplementing histological examination, and allowing a differential diagnosis between PTC and HTT...
  50. ncbi request reprint Pathology and molecular genetics of the pituitary gland in patients with the 'complex of spotty skin pigmentation, myxomas, endocrine overactivity and schwannomas' (Carney complex)
    Constantine A Stratakis
    Section on Endocrinology and Genetics, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, MD 20892 1862, USA
    Front Horm Res 32:253-64. 2004
    ....
  51. doi request reprint Large deletions of the PRKAR1A gene in Carney complex
    Anelia Horvath
    Section on Endocrinology and Genetics and Pediatric Endocrinology Training Program, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892, USA
    Clin Cancer Res 14:388-95. 2008
    ..Although a few families map to chromosome 2, it is possible that current sequencing techniques do not detect larger gene changes in PRKAR1A -- mutation-negative individuals with Carney complex...